1.0 2026-08-17 23:29:54 UTC 2026-08-17 23:29:54 UTC (5s)-1-methyl-5-pyridin-3-ylpyrrolidin-2-one SmallMolecule (5s)-1-methyl-5-pyridin-3-ylpyrrolidin-2-one belongs to the pyrrolidinylpyridines, a subclass of pyridines and derivatives within the organic compounds. This organoheterocyclic compound has the formula C10H12N2O and an average molecular weight of 176.21 g/mol. It serves as a biological metabolite (PMC12312644, PMC7908579, PMC9025817, PMC9214275, PMC9357114) and a biological biomarker (PMC11157951, PMC7140578). The compound is found in or released from six recorded sources, including tobacco pipes, tobacco product cases, other smoking requisites, pipe accessories, non electric simulated smoking devices, and household cleaning & consumer products. The compound is associated with several health effects, including headache (PMC12255647), depression (PMC11157951), and lung cancer (PMC2891118). It is linked to an increase in blood pressure (PMC8713646), an increase in overweight (PMC10035292), and an increase in obesity (PMC10035292), as well as obesity generally (PMC10035292). Additionally, it is associated with a decrease in low birth weight (PMC12321497). In clinical observations, levels of (5s)-1-methyl-5-pyridin-3-ylpyrrolidin-2-one are elevated in the blood of individuals with asthma (PMC11282223). C10H12N2O 176.21 176.094963 486-56-6 InChI=1S/C10H12N2O/c1-12-9(4-5-10(12)13)8-3-2-6-11-7-8/h2-3,6-7,9H,4-5H2,1H3/t9-/m0/s1 UIKROCXWUNQSPJ-VIFPVBQESA-N Detected and Not Quantified logp -0.3 average_mass 176.21 ChemAxon mono_mass 176.094963 ChemAxon formula C10H12N2O ChemAxon inchi InChI=1S/C10H12N2O/c1-12-9(4-5-10(12)13)8-3-2-6-11-7-8/h2-3,6-7,9H,4-5H2,1H3/t9-/m0/s1 ChemAxon inchikey UIKROCXWUNQSPJ-VIFPVBQESA-N ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f7226d17aa0> 854019