Diazinon (CED0000040)

Record Information

Version

1.0

Creation Date

2009-03-06 18:58:00 UTC

Update Date

2026-08-18 20:16:55 UTC

Accession Number

CHEM000052

Identification

Common Name

Diazinon

Class

Small Molecule

Description

Diazinon (C12H21N2O3PS) is an exogenous liquid with an average molecular weight of 304.35 g/mol. Diazinon belongs to the thiophosphoric acid esters, a subclass of organic thiophosphoric acids and derivatives within the organic compounds. It is utilized as an agrochemical, acaricide, nematicide, and pesticide (PMC11940157, PMC4439093). Industrially, it is classified as a biocide, a degradant or impurity, and an organophosphate or organophosphorus insecticide (PMC10451336, PMC8348328, PMC4227495, PMC10039801). Biologically, it functions as an insecticide (PMC12694732, PMC3013756, PMC7768353, PMC3108137) and acts as an inhibitor of cholinesterase (EC 3.1.1.8) and acetylcholinesterase (EC 3.1.1.7). The compound has been recorded in 37 sources, including pesticides in agriculture and land management, drinking water, food contact materials, and various electronic equipment, building materials, and household cleaning products. Exposure occurs via touch, oral ingestion, and inhalation (PMC4025031). Diazinon targets several proteins, including the aryl hydrocarbon receptor (AHR), C-C motif chemokine 2 (CCL2), Cytochrome P450 1A1 (CYP1A1), and Cytochrome P450 1A2 (CYP1A2). Its main toxic intermediate, diazoxon, inhibits liver kynurenine formamidase and acetylcholinesterase in the peripheral and central nervous systems. This inhibition leads to acetylcholine accumulation, causing hyperpolarization, receptor desensitization, and excessive stimulation of cholinergic fibers in the central nervous system, neuromuscular junctions of skeletal muscles, and postganglionic parasympathetic nerve endings, resulting in nicotinic, muscarinic, and CNS effects. Health effects associated with diazinon include inflammation (PMC5220052), increased blood pressure (PMC9358881), weight gain (PMC5325319), dizziness, respiratory paralysis, and brain cancer (PMC8623664), as well as cancer (PMC11757986) and non-Hodgkin lymphoma (PMC11664077).

Contaminant Type

Food Toxin
Household Toxin
Human Neurotoxin
Insecticide
Metabolite
Organic Compound
Organophosphate
Pesticide
Synthetic Compound

Chemical Structure

MOL SDF PDB SMILES InChI

Synonyms

Value	Source
Dimpylate	ChEBI
O,O-Diethyl 2-isopropyl-4-methylpyrimidyl-6-thiophosphate	ChEBI
O,O-Diethyl O-(2-isopropyl-4-methyl-6-pyrimidyl) thionophosphate	ChEBI
O,O-Diethyl O-(2-isopropyl-6-methyl-4-pyrimidinyl) phosphorothioate	ChEBI
O,O-Diethyl O-[6-methyl-2-(1-methylethyl)pyrimidin-4-yl] thiophosphate	ChEBI
Phosphorothioic acid, O,O-diethyl O-(6-methyl-2-(1-methylethyl)-4-pyrimidinyl) ester	ChEBI
New Z diazinon	Kegg
Optimizer insecticide	Kegg
Dimpylic acid	Generator
O,O-Diethyl 2-isopropyl-4-methylpyrimidyl-6-thiophosphoric acid	Generator
O,O-Diethyl O-(2-isopropyl-4-methyl-6-pyrimidyl) thionophosphoric acid	Generator
O,O-Diethyl O-(2-isopropyl-6-methyl-4-pyrimidinyl) phosphorothioic acid	Generator
O,O-Diethyl O-[6-methyl-2-(1-methylethyl)pyrimidin-4-yl] thiophosphoric acid	Generator
Phosphorothioate, O,O-diethyl O-(6-methyl-2-(1-methylethyl)-4-pyrimidinyl) ester	Generator
Bazudine	MeSH
Neocidol	MeSH
Neotsidol	MeSH
Agridin 60	HMDB
Alfa-tox	HMDB
Antigal	HMDB
Antlak	HMDB
Bassadinon	HMDB
Basudin	HMDB
Bazuden	HMDB
Bazudin	HMDB
Ciazinon	HMDB
Compass	HMDB
Dacutox	HMDB
Dassitox	HMDB
Dazzel	HMDB
Delzinon	HMDB
Diagran	HMDB
Dianon	HMDB
Diazide	HMDB
Diazinone	HMDB
Diazitol	HMDB
Diazol	HMDB
Dicid	HMDB
Diethyl 2-isopropyl-4-methyl-6-pyrimidyl thionophosphate	HMDB
Diethyl dimpylatum	HMDB
Dimpylate, inn	HMDB
Dipofene	HMDB
Disonex	HMDB
Dizictol	HMDB
Diziktol	HMDB
Dizinil	HMDB
Dizinon	HMDB
Drawizon	HMDB
Dyzol	HMDB
Ektoband	HMDB
Exodin	HMDB
Fezudin	HMDB
Flytrol	HMDB
Galesan	HMDB
Gardentox	HMDB
Isopropylmethylpyrimidyl diethyl thiophosphate	HMDB
Kayazinon	HMDB
Kayazol	HMDB
Knox-out	HMDB
Meodinon	HMDB
Nedcidol	HMDB
Neodinon	HMDB
Nipsan	HMDB
Nucidol	HMDB
Oleodiazinon	HMDB
Optimizer	HMDB
Root guard	HMDB
Sarolex	HMDB
Spectracide	HMDB
Spertacide	HMDB
Srolex	HMDB
Terminator	HMDB

Chemical Formula

C₁₂H₂₁N₂O₃PS

Average Molecular Mass

304.346 g/mol

Monoisotopic Mass

304.101 g/mol

CAS Registry Number

333-41-5

IUPAC Name

O,O-diethyl O-6-methyl-2-(propan-2-yl)pyrimidin-4-yl phosphorothioate

Traditional Name

diazinon

SMILES

CCOP(=S)(OCC)OC1=NC(=NC(C)=C1)C(C)C

InChI Identifier

InChI=1S/C12H21N2O3PS/c1-6-15-18(19,16-7-2)17-11-8-10(5)13-12(14-11)9(3)4/h8-9H,6-7H2,1-5H3

InChI Key

FHIVAFMUCKRCQO-UHFFFAOYSA-N

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as pyrimidinyl phosphorothioates. These are organic compounds containing the thiophosphoric acid functional group or a derivative thereof, with the general structure ROP(OR')(OR'')=S, where R= pyrimidine, R' = organyl group , and R\" = any atom.

Kingdom

Organic compounds

Super Class

Organic acids and derivatives

Class

Organic thiophosphoric acids and derivatives

Sub Class

Thiophosphoric acid esters

Direct Parent

Pyrimidinyl phosphorothioates

Alternative Parents

Substituents

Pyrimidinyl phosphorothioate
Thiophosphate triester
Pyrimidine
Heteroaromatic compound
Azacycle
Organoheterocyclic compound
Organic nitrogen compound
Organic oxygen compound
Organopnictogen compound
Hydrocarbon derivative
Organooxygen compound
Organonitrogen compound
Aromatic heteromonocyclic compound

Molecular Framework

Aromatic heteromonocyclic compounds

External Descriptors

pyrimidines (CHEBI:34682 )
organic thiophosphate (CHEBI:34682 )
Organophosphorus insecticides (C14324 )
a small molecule (CPD-8965 )

Biological Properties

Status

Detected and Not Quantified

Origin

Exogenous

Cellular Locations

Membrane

Biofluid Locations

Not Available

Tissue Locations

Not Available

Applications

Biological Roles

Chemical Roles

Organoleptic Effects

Not Available

Physical Properties

State

Liquid

Appearance

Colorless oil (pure) or pale to dark brown liquid (technical).

Experimental Properties

Property	Value
Melting Point	< 25°C
Boiling Point	Not Available
Solubility	0.04 mg/mL at 25°C

Predicted Properties

Property	Value	Source
Water Solubility	0.035 g/L	ALOGPS
logP	4.45	ALOGPS
logP	4.19	ChemAxon
logS	-3.9	ALOGPS
pKa (Strongest Basic)	4.19	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	2	ChemAxon
Hydrogen Donor Count	0	ChemAxon
Polar Surface Area	53.47 Å²	ChemAxon
Rotatable Bond Count	7	ChemAxon
Refractivity	80.76 m³·mol⁻¹	ChemAxon
Polarizability	31.48 Å³	ChemAxon
Number of Rings	1	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	Yes	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

Spectra

Spectrum Type	Description	Splash Key	Deposition Date	View
GC-MS	GC-MS Spectrum	splash10-0ufr-3931000000-a70584cb463b92093849	Not Available	View Spectrum
GC-MS	GC-MS Spectrum	splash10-0ufr-3931000000-a70584cb463b92093849	Not Available	View Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum	splash10-03g1-2390000000-64dc2c6900828222f0d0	Not Available	View Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum	Not Available	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-0a4i-0009000000-d239df985b8529964c59	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-0ldi-0915000000-ced91e8448a6f8b1969d	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-0gb9-0900000000-48faf44580abfbba15e2	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-0gb9-0900000000-109fa8436bb829f5f481	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-0gb9-0900000000-49a403503b8e1237dddc	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-0gb9-0900000000-373a091bd4e337f273ac	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-0a4i-0009000000-25cf20e874bc51155b11	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-0pvi-0905000000-89807ca393822677be3e	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-0gb9-0900000000-95716b221cd9e83e7d05	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-0gb9-1900000000-3772ba2a27f51803e58a	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-0uxs-4900000000-ce1c6d19b36209036e3a	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-0w2a-6900000000-8011c485731c42bd49f7	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-0a4i-0009000000-e92acd83cf908233bd11	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-0aor-0905000000-54dc7dc28ca7ec93789e	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-0gb9-0900000000-cf4033176e3d7c36c589	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-0gb9-1900000000-cb95f2a89d6871b4c0f5	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-0uxs-3900000000-8d43918e6bdf5a791827	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-0w2a-7900000000-37289512a80be0d06b70	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-0gb9-0900000000-c242d24704a15f911a56	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-0gb9-1900000000-fde2fd32fffda1ea9300	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-0uxs-3900000000-45cba0af187739d41594	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-0gb9-0900000000-092c7381e77775c2bc1b	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-0gb9-4900000000-331cd31f4c4183b8f4e9	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-0aor-0906000000-f67144c408283733b2f3	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-0gb9-1900000000-d4cd9b399d1f5fe8018b	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-0gb9-0900000000-23caa51263fb2d1f1f9e	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-0uxs-3900000000-5f37200ecde5e6e03522	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-0a4i-0009000000-0def909dfd1a34688c6f	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-0ldi-0915000000-16d76f0dea1f587c2f15	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-0gb9-0900000000-7d84184cd4de06f02378	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-0gb9-0900000000-71a59f07cef5df275d08	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-0gb9-0900000000-2f7c8c621d6148af67dc	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-0gb9-0900000000-caf13a2f9a28966fd1f4	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-0pvi-0905000000-9e479b4f966d66375095	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-0a4i-0009000000-25cf20e874bc51155b11	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-0gb9-1900000000-3cdcd3790d140e3fb637	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-0uxs-4900000000-8dfdb14ebbe07dc65c78	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-0gb9-0900000000-a3a9e7c943e099f33275	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-0gb9-0900000000-013edcdd5d1a97ed7c74	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-0aor-0905000000-03abd1b09a6f68336eac	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-0w2a-6900000000-8011c485731c42bd49f7	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-0a4i-0009000000-872a393708f6ae285f4e	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-0aor-0906000000-933b4457ff574563bdbf	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-0gb9-0900000000-7101d86decc6c087bc16	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-0w2a-7900000000-37289512a80be0d06b70	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-0gb9-0900000000-f955cfa8f0726f4b2dfe	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-0uxs-3900000000-45cba0af187739d41594	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-0gb9-1900000000-af399bab883fb0b55715	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-0a4i-2398000000-292315df845ad237142a	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-002k-2490000000-b8c16809eaddcd92f2fb	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-00ko-9410000000-169637cf10237dcb2a0f	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-0ufr-0694000000-cdcbf19ad7bf249fbdb6	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-00fs-0890000000-0b16a5fb1c0467d0de87	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-000b-0980000000-0e6aa8e81cb45755aac9	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-0a4i-0309000000-c6d2c987ccf4215926a9	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-0udi-0932000000-0a25f121466362ef83b4	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-000i-5900000000-f2072aa2400458deb12c	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-0udi-0229000000-f7f2aaf02aae24e840c0	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-000i-0910000000-45417aaa50f0c35af06a	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-000i-0900000000-5356c8a1372bb3bde484	Not Available	View Spectrum
MS	MS Spectrum	splash10-0fbi-7920000000-dce70eb9e413a5f2e1a2	Not Available	View Spectrum

Toxicity Profile

Mechanism of Toxicity

Diazinon is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinesterase. Because of its essential function, chemicals that interfere with the action of acetylcholinesterase are potent neurotoxins, causing excessive salivation and eye-watering in low doses, followed by muscle spasms and ultimately death. Nerve gases and many substances used in insecticides have been shown to act by binding a serine in the active site of acetylcholine esterase, inhibiting the enzyme completely. Acetylcholine esterase breaks down the neurotransmitter acetylcholine, which is released at nerve and muscle junctions, in order to allow the muscle or organ to relax. The result of acetylcholine esterase inhibition is that acetylcholine builds up and continues to act so that any nerve impulses are continually transmitted and muscle contractions do not stop. Among the most common acetylcholinesterase inhibitors are phosphorus-based compounds, which are designed to bind to the active site of the enzyme. The structural requirements are a phosphorus atom bearing two lipophilic groups, a leaving group (such as a halide or thiocyanate), and a terminal oxygen.

Carcinogenicity (IARC Classification)

Spraying and application of nonarsenical insecticides entail exposures that are probably carcinogenic to humans (Group 2A). (4)

Minimum Risk Level

Intermediate Inhalation: 0.01 mg/m3 (3) Acute Oral: 0.006 mg/kg/day (3) Intermediate Oral: 0.002 mg/kg/day (3) Chronic Oral: 0.0007 mg/kg/day (3)

Symptoms

The symptoms associated with diazinon poisoning in humans include weakness, headaches, tightness in the chest, blurred vision, nonreactive pinpoint pupils, excessive salivation, difficulty breathing, sweating, nausea, vomiting, diarrhea, abdominal cramps, and slurred speech. (6)

Treatment

If the compound has been ingested, rapid gastric lavage should be performed using 5% sodium bicarbonate. For skin contact, the skin should be washed with soap and water. If the compound has entered the eyes, they should be washed with large quantities of isotonic saline or water. In serious cases, atropine and/or pralidoxime should be administered. Anti-cholinergic drugs work to counteract the effects of excess acetylcholine and reactivate AChE. Atropine can be used as an antidote in conjunction with pralidoxime or other pyridinium oximes (such as trimedoxime or obidoxime), though the use of '-oximes' has been found to be of no benefit, or possibly harmful, in at least two meta-analyses. Atropine is a muscarinic antagonist, and thus blocks the action of acetylcholine peripherally.

Toxicity Values

Toxicity Value	Unit	Value Range	Organism	Dose Descriptor	Route of Exposure	Predicted or Experimental	Reference
66.0	mg/kg	Not Available	Rat	LD50	Oral	experimental	T14
180.0	mg/kg	Not Available	Rat	LD50	Dermal	experimental	T14
65.0	mg/kg	Not Available	Rat	LD50	Intraperitoneal	experimental	T14
58.0	mg/kg	Not Available	Mouse	LD50	Subcutaneous	experimental	T14
180.0	mg/kg	Not Available	Mouse	LD50	Intravenous	experimental	T14

Health Effects

Health Effect	Relationship	Direction	Reference
blood pressure	associated_with	increase	PMC9358881
inflammation	associated_with	increase	PMC5220052
inflammation	associated_with	Not Available	PMC5220052
cancer	associated_with	Not Available	PMC11757986
dizziness	associated_with	Not Available	PMC8623664
weight gain	associated_with	increase	PMC5325319
non-Hodgkin lymphoma	associated_with	Not Available	PMC11664077
brain cancer	associated_with	Not Available	PMC8623664
respiratory paralysis	associated_with	Not Available	PMC8623664

Exposure Sources

Source ID	Source	Sector	Reference
7	Pesticides	Agriculture & land management	Not Available
10	Insecticides	Agriculture & land management	Not Available
115	Drinking water	Drinking water & water supply	Not Available
233	Brushes	Personal care & cosmetics	Not Available
494	Food contact materials	Food, food processing & cookware	Not Available
499	Roofs	Building & Construction	Not Available
501	Sunshades Awnings Or Outside Screens	Building & Construction	Not Available
502	Sunshades Awnings Or Outside Screens	Building & Construction	Not Available
503	Tents Or Canopies	Building & Construction	Not Available
505	Amplifiers	Electrical & Electronic Equipment	Not Available
506	Antennas	Electrical & Electronic Equipment	Not Available
508	Coils	Electrical & Electronic Equipment	Not Available
509	Colour Television Systems	Electrical & Electronic Equipment	Not Available
511	Conductors Or Conductive Bodies Characterised By The Conductive Materials	Electrical & Electronic Equipment	Not Available
514	Discharge Lamps	Electrical & Electronic Equipment	Not Available
516	Electric Hearing Aids	Electrical & Electronic Equipment	Not Available
517	Electric Switches	Electrical & Electronic Equipment	Not Available
518	Electrically Stimulated Smoking Devices	Electrical & Electronic Equipment	Not Available
519	Electrodes	Electrical & Electronic Equipment	Not Available
520	Emergency Protective Devices	Electrical & Electronic Equipment	Not Available
521	Fixed Capacitors And Their Manufacture	Electrical & Electronic Equipment	Not Available
524	Hybrid Capacitors	Electrical & Electronic Equipment	Not Available
525	Line Transmission Systems	Electrical & Electronic Equipment	Not Available
527	Magnets	Electrical & Electronic Equipment	Not Available
528	Microphones	Electrical & Electronic Equipment	Not Available
529	Power Cables	Electrical & Electronic Equipment	Not Available
530	Radio Transmission Systems	Electrical & Electronic Equipment	Not Available
531	Relays	Electrical & Electronic Equipment	Not Available
532	Selectors	Electrical & Electronic Equipment	Not Available
537	Television Systems	Electrical & Electronic Equipment	Not Available
539	Video Games	Electrical & Electronic Equipment	Not Available
544	Fermentation Processes For Beer	Food, food processing & cookware	Not Available
545	Food Preservation	Food, food processing & cookware	Not Available
547	Preparation Of Malt	Food, food processing & cookware	Not Available
551	Processing Fish	Food, food processing & cookware	Not Available
556	Cigar Cigarettes	Household cleaning & consumer products	Not Available
561	Perfumes Within Detergents And Soaps	Household cleaning & consumer products	Not Available
563	Soap Detergents	Household cleaning & consumer products	Not Available
569	Tobacco Smoke Filters	Household cleaning & consumer products	Not Available
579	Manufacture Of Iron Or Steel	Industrial manufacturing & chemical processing	Not Available
580	Manufacture Preparation Of Tobacco Products	Industrial manufacturing & chemical processing	Not Available
581	Paper Making Machines	Industrial manufacturing & chemical processing	Not Available
583	Anchoring Equipment	Marine, shipping & aquaculture	Not Available
584	Buoys	Marine, shipping & aquaculture	Not Available
589	Life Buoys	Marine, shipping & aquaculture	Not Available
590	Lifeboat Equipment	Marine, shipping & aquaculture	Not Available
592	Marine Propulsion Or Steering	Marine, shipping & aquaculture	Not Available
596	Acaricides	Agriculture & land management	Not Available
597	Chemosterilants	Agriculture & land management	Not Available
598	Fertiliser Distributors	Agriculture & land management	Not Available
600	Herbicides And Algicides	Agriculture & land management	Not Available
601	Lawn Mowers	Agriculture & land management	Not Available
602	Molluscicides	Agriculture & land management	Not Available
603	Nematocides	Agriculture & land management	Not Available
604	Pest Attractants	Agriculture & land management	Not Available
605	Pest Repellants	Agriculture & land management	Not Available
606	Plant Growth Regulators	Agriculture & land management	Not Available
607	Rodenticides(1)	Agriculture & land management	Not Available
608	Rodenticides	Agriculture & land management	Not Available
609	Aftershave	Personal care & cosmetics	Not Available
610	Aftersun Products	Personal care & cosmetics	Not Available
611	Anti Perspirants Or Body Deoderants	Personal care & cosmetics	Not Available
612	Body Washing Or Cleaning Implements	Personal care & cosmetics	Not Available
613	Depilatories	Personal care & cosmetics	Not Available
614	Essential Oils Or Perfumes	Personal care & cosmetics	Not Available
615	Eye Makeup Products	Personal care & cosmetics	Not Available
617	Lip Care Products	Personal care & cosmetics	Not Available
618	Lip Makeup Products	Personal care & cosmetics	Not Available
624	Merry Go Rounds	Recreation & sports surfaces	Not Available
630	Toys	Recreation & sports surfaces	Not Available
632	Apparel	Textiles, leather & furnishings	Not Available
633	Azo Dyes	Textiles, leather & furnishings	Not Available
634	Buckles	Textiles, leather & furnishings	Not Available
642	Footwear	Textiles, leather & furnishings	Not Available
643	Headwear	Textiles, leather & furnishings	Not Available
648	Nitro Dyes	Textiles, leather & furnishings	Not Available
650	Purses Luggage Hand Bags	Textiles, leather & furnishings	Not Available
652	Ropes	Textiles, leather & furnishings	Not Available
653	Sewing	Textiles, leather & furnishings	Not Available
655	Slide Fasteners	Textiles, leather & furnishings	Not Available
662	Yarns Or Threads	Textiles, leather & furnishings	Not Available

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this synthetic chemical

Targets

Structure	Protein	UniProt ID	Organism	Relationship	Details
Click to view 3D structure	Acetylcholinesterase	K4JQ36	Laodelphax striatella	Predicted (SEA)	0.155698
Click to view 3D structure	Carbonic anhydrase 9	Q16790	Humans	Predicted (SEA)	4381.98
Click to view 3D structure	Carbonic anhydrase 12	O43570	Humans	Predicted (SEA)	4176.61
Click to view 3D structure	Carbonic anhydrase 7	P43166	Humans	Predicted (SEA)	3780.12
Click to view 3D structure	Carbonic anhydrase 14	Q9ULX7	Humans	Predicted (SEA)	3045.7
Click to view 3D structure	Carbonic anhydrase 5B, mitochondrial	Q9Y2D0	Humans	Predicted (SEA)	2775.64
Click to view 3D structure	Carbonic anhydrase 6	P23280	Humans	Predicted (SEA)	3097.39
Click to view 3D structure	Carbonic anhydrase 4	P22748	Humans	Predicted (SEA)	3743.61
Click to view 3D structure	Monoglyceride lipase	O35678	Mus musculus	Predicted (SEA)	1310.05
Click to view 3D structure	Fatty-acid amide hydrolase 1	O08914	Mus musculus	Predicted (SEA)	2172.46
Click to view 3D structure	Cannabinoid receptor 1	P47746	Mus musculus	Predicted (SEA)	1340.25
Click to view 3D structure	Acetylcholinesterase	P21836	Mus musculus	Predicted (SEA)	2700.98
Click to view 3D structure	Mitogen-activated protein kinase 8	P45983	Humans	Predicted (SEA)	7330.36
Click to view 3D structure	Carbonic anhydrase 5A, mitochondrial	P35218	Humans	Predicted (SEA)	4288.4
Click to view 3D structure	Cholinesterase	P06276	Humans	Predicted (SEA)	5826.78
Click to view 3D structure	Carbonic anhydrase 3	P07451	Humans	Predicted (SEA)	2875.13
Click to view 3D structure	Corticotropin-releasing factor receptor 1	P34998	Humans	Predicted (SEA)	268.191
Click to view 3D structure	Acetylcholinesterase	P22303	Humans	Predicted (SEA)	6913.01
Click to view 3D structure	Serine/threonine-protein kinase D3	O94806	Humans	Predicted (SEA)	7295.25
Click to view 3D structure	Corticotropin-releasing factor receptor 1	P35353	Rattus norvegicus	Predicted (SEA)	200.384
Click to view 3D structure	Streptokinase A	P10520	Streptococcus pyogenes serotype M1	Predicted (SEA)	6785.49
Click to view 3D structure	Carbonic anhydrase 13	Q8N1Q1	Humans	Predicted (SEA)	3632.52
Click to view 3D structure	Carbonic anhydrase 2	P00918	Humans	Predicted (SEA)	6543.62
Click to view 3D structure	Mitogen-activated protein kinase 9	P45984	Humans	Predicted (SEA)	7390.46
Click to view 3D structure	Carbonic anhydrase 1	P00915	Humans	Predicted (SEA)	6290.84
Click to view 3D structure	Acetylcholinesterase	P22303	Humans	Known	Diazoxon the main toxic intermediate of diazinon, inhibits acetylcholinesterase in the central and peripheral nervous system. This results in the accumulation of acetylcholine, causing excessive stimulation of cholinergic fibers in the postganglionic parasympathetic nerve endings, neuromuscular junctions of the skeletal muscles, and cells of the central nervous system that results in hyperpolarization and receptor desensitization. This produces muscarinic, nicotinic, and CNS effects. (L162)
Click to view 3D structure	Cholinesterase	P06276	Humans	Known	Not Available
Click to view 3D structure	Cytochrome P450 1A2	P05177	Humans	Known	Not Available
Click to view 3D structure	Cytochrome P450 3A4	P08684	Humans	Known	Not Available
Click to view 3D structure	Cytochrome P450 2B6	P20813	Humans	Known	Not Available
Click to view 3D structure	C-C motif chemokine 2	P13500	Humans	Known	Not Available
Click to view 3D structure	Cytochrome P450 1A1	P04798	Humans	Known	Not Available
Click to view 3D structure	Aryl hydrocarbon receptor	P35869	Humans	Known	Not Available
Click to view 3D structure	Sulfotransferase 2A1	Q06520	Humans	Known	Not Available
Click to view 3D structure	Cytochrome P450 2C19	P33261	Humans	Known	Not Available
Click to view 3D structure	UDP-glucuronosyltransferase 1A1	P22309	Humans	Known	Not Available