2,4-Dichlorophenoxyacetic acid (CED0003331)

Record Information

Version

1.0

Creation Date

2009-03-06 18:58:22 UTC

Update Date

2026-08-24 21:49:50 UTC

Accession Number

CHEM000217

Identification

Common Name

2,4-Dichlorophenoxyacetic acid

Class

Small Molecule

Description

2,4-Dichlorophenoxyacetic acid (C8H6Cl2O3) is a solid at room temperature with an average molecular weight of 221.04 g/mol. It is an exogenous compound. 2,4-Dichlorophenoxyacetic acid belongs to the phenoxyacetic acid derivatives, a subclass of benzene and substituted derivatives within the organic compounds. This compound serves several roles and uses, acting as a synthetic auxin, herbicide (PMC10620202, PMC9147642, PMC9419126), pesticide (PMC10004630, PMC11359687), and biocide (PMC10620202, PMC9147642, PMC9419126). It is further utilized as an agrochemical, defoliant (PMC10620202, PMC9147642, PMC9419126), insecticide (PMC4025031), and industrial degradant or impurity (PMC10620202, PMC9147642, PMC9419126). Biologically, it functions as an EC 1.1.1.25 (shikimate dehydrogenase) inhibitor (PMC10620202, PMC9147642, PMC9419126). It is identified as an environmental contaminant (PMC11596083). The compound is found in or released from 57 recorded sources, including drinking water, household items such as rosaries and credit card holders, building and construction materials like roofs, floors, and ceilings, and food processing activities including the preparation of wine, beer, and malt. It is also associated with electrical and electronic equipment and various household cleaning and consumer products. The recorded route of exposure is oral. At a molecular level, 2,4-Dichlorophenoxyacetic acid has seven recorded protein targets, including Cytochrome P450 2B6 (CYP2B6), Interleukin-1 alpha (IL1A), Sex hormone-binding globulin (SHBG), and Urokinase plasminogen activator surface receptor (PLAUR). Health effects associated with the compound include cancer (PMC4782969), as well as non-Hodgkin lymphoma and prostate cancer (PMC3734498).

Contaminant Type

Aromatic Hydrocarbon
Ether
Household Toxin
Human Neurotoxin
Industrial/Workplace Toxin
Metabolite
Organic Compound
Organochloride
Pesticide
Pollutant
Synthetic Compound

Chemical Structure

MOL SDF PDB SMILES InChI

Synonyms

Value	Source
(2,4-Dichlorphenoxy)essigsaeure	ChEBI
2,4-D acid	ChEBI
2,4-Dichlorophenoxyacetate	ChEBI
2,4-Dichlorphenoxyessigsaeure	ChEBI
Acide 2,4-dichloro phenoxyacetique	ChEBI
Hedonal	ChEBI
Trinoxol	ChEBI
2,4-D	Kegg
(2, 4-Dichlorophenoxy)acetic acid	HMDB
(2,4-Dichloor-fenoxy)-azijnzuur	HMDB
(2,4-Dichlor-phenoxy)-essigsaeure	HMDB
(2,4-Dichlorophenoxy)-acetic acid	HMDB
(2,4-Dichlorophenoxy)acetic acid	HMDB
(2,4-Dichlorophenoxy)acetic acid (acd/name 4.0)	HMDB
(2,4-Dichlorophenyloxy)acetic acid	HMDB
(2,4-Dichlorphenoxy)acetic acid	HMDB
(2,4-Dichlorphenoxy)essigsaure	HMDB
(Dichlorophenoxy)acetic acid	HMDB
2,4-D Mecoprop	HMDB
2,4-Dichlorophenoxyethanoic acid	HMDB
2,4-Dichlorphenoxyessigsaure	HMDB
2,4-Dwuchlorofenoksyoctowy kwas	HMDB
Acido(2,4-dicloro-fenossi)-acetico	HMDB
Acme amine 4	HMDB
Acme butyl ester 4	HMDB
Acme LV 4	HMDB
Agrotect	HMDB
Amidox	HMDB
Aminopielik 50Sl	HMDB
Amoxone	HMDB
Aqua-kleen	HMDB
Atlas D	HMDB
b-Selektonon	HMDB
Barrage HF	HMDB
Brush-rhap	HMDB
Chipco turf herbicide D	HMDB
Chipco turf herbicide quot dquot	HMDB
Chloroxone	HMDB
Crop rider	HMDB
Crotilin	HMDB
Dacamine	HMDB
Debroussaillant 600	HMDB
Decamine	HMDB
Ded-weed	HMDB
Ded-weed LV-69	HMDB
Desormone	HMDB
Dezormon	HMDB
Diclordon	HMDB
Dicopur	HMDB
Dicotox	HMDB
Dinoxol	HMDB
DMA-4	HMDB
Dormone	HMDB
Emulsamine BK	HMDB
Emulsamine e-3	HMDB
Envert 171	HMDB
Envert DT	HMDB
Esteron	HMDB
Esteron 44 weed killer	HMDB
Esteron 76 be	HMDB
Esteron 99	HMDB
Esteron 99 concentrate	HMDB
Esteron brush killer	HMDB
Esterone	HMDB
Esterone four	HMDB
Estone	HMDB
Farmco	HMDB
Fernesta	HMDB
Fernimine	HMDB
Fernoxone	HMDB
Ferxone	HMDB
Foredex 75	HMDB
Formula 40	HMDB
Hedonal (the herbicide)	HMDB
Hedonal, herbicide	HMDB
Herbidal	HMDB
Huragan	HMDB
Ipaner	HMDB
Krotiline	HMDB
Kwas 2,4-dwuchlorofenoksyoctowy	HMDB
Kwasu 2,4-dwuchlorofenoksyoctowego	HMDB
Kyselina 2,4-dichlorfenoxyoctova	HMDB
Lawn-keep	HMDB
Macrondray	HMDB
Miracle	HMDB
Monosan	HMDB
Mota maskros	HMDB
Moxone	HMDB
Netagrone	HMDB
Netagrone 600	HMDB
Pennamine	HMDB
Pennamine D	HMDB
Phenox	HMDB
Pielik	HMDB
Planotox	HMDB
Plantgard	HMDB
RCRA waste number u240	HMDB
Rhodia	HMDB
Salvo	HMDB
Spontox	HMDB
Spritz-hormin/2,4-D	HMDB
Spritz-hormit/2,4-D	HMDB
Super D weedone	HMDB
Superormone concentre	HMDB
Tiller S	HMDB
Transamine	HMDB
Tributon	HMDB
Uniso	HMDB
Vergemaster	HMDB
Verton	HMDB
Verton 2-D	HMDB
Verton 2D	HMDB
Verton D	HMDB
Vertron 2D	HMDB
Vidon 638	HMDB
Visko-rhap	HMDB
Visko-rhap low drift herbicides	HMDB
Visko-rhap low volatile 4l	HMDB
Weed tox	HMDB
Weed-ag-bar	HMDB
Weed-b-gon	HMDB
Weed-rhap	HMDB
Weedar	HMDB
Weedar-64	HMDB
Weedatul	HMDB
Weedez wonder bar	HMDB
Weedone	HMDB
Weedone LV4	HMDB
Weedtrol	HMDB
2,4-Dichlorophenoxyacetic acid, potassium salt	HMDB
2,4-Dichlorophenoxyacetic acid, ammonium salt	HMDB
2,4-Dichlorophenoxyacetic acid, lithium salt	HMDB
2,4-Dichlorophenoxyacetic acid, sodium salt	HMDB
2,4 Dichlorophenoxyacetic acid	HMDB
2,4-Dichlorophenoxyacetic acid	ChEBI

Chemical Formula

C₈H₆Cl₂O₃

Average Molecular Mass

221.037 g/mol

Monoisotopic Mass

219.969 g/mol

CAS Registry Number

94-75-7

IUPAC Name

2-(2,4-dichlorophenoxy)acetic acid

Traditional Name

rhodia

SMILES

OC(=O)COC1=C(Cl)C=C(Cl)C=C1

InChI Identifier

InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12)

InChI Key

OVSKIKFHRZPJSS-UHFFFAOYSA-N

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as chlorophenoxyacetates. Chlorophenoxyacetates are compounds containing a phenoxyacetate that carries one or more chlorine atoms on the benzene ring.

Kingdom

Organic compounds

Super Class

Benzenoids

Class

Benzene and substituted derivatives

Sub Class

Phenoxyacetic acid derivatives

Direct Parent

Chlorophenoxyacetates

Alternative Parents

Substituents

Chlorophenoxyacetate
Phenoxy compound
1,3-dichlorobenzene
Phenol ether
Alkyl aryl ether
Chlorobenzene
Halobenzene
Aryl chloride
Aryl halide
Monocarboxylic acid or derivatives
Ether
Carboxylic acid
Carboxylic acid derivative
Organochloride
Organohalogen compound
Organic oxygen compound
Carbonyl group
Organooxygen compound
Organic oxide
Hydrocarbon derivative
Aromatic homomonocyclic compound

Molecular Framework

Aromatic homomonocyclic compounds

External Descriptors

dichlorobenzene (CHEBI:28854 )
chlorophenoxyacetic acid (CHEBI:28854 )
Phenoxy herbicides (C03664 )

Biological Properties

Status

Detected and Not Quantified

Origin

Exogenous

Cellular Locations

Membrane

Biofluid Locations

Not Available

Tissue Locations

Not Available

Applications

Biological Roles

Chemical Roles

EC 1.1.1.25 (shikimate dehydrogenase) inhibitor

Organoleptic Effects

Not Available

Physical Properties

State

Solid

Appearance

White to yellow powder. (11)

Experimental Properties

Property	Value
Melting Point	140.5°C
Boiling Point	160 °C (0.4 mm Hg)
Solubility	0.677 mg/mL at 25°C

Predicted Properties

Property	Value	Source
Water Solubility	0.55 g/L	ALOGPS
logP	2.82	ALOGPS
logP	2.5	ChemAxon
logS	-2.6	ALOGPS
pKa (Strongest Acidic)	2.81	ChemAxon
pKa (Strongest Basic)	-4.9	ChemAxon
Physiological Charge	-1	ChemAxon
Hydrogen Acceptor Count	3	ChemAxon
Hydrogen Donor Count	1	ChemAxon
Polar Surface Area	46.53 Å²	ChemAxon
Rotatable Bond Count	3	ChemAxon
Refractivity	48.22 m³·mol⁻¹	ChemAxon
Polarizability	19.28 Å³	ChemAxon
Number of Rings	1	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

Spectra

Spectrum Type	Description	Splash Key	Deposition Date	View
Predicted GC-MS	Predicted GC-MS Spectrum	splash10-008c-5930000000-9e18343a9f7af8f4a0e7	Not Available	View Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum	splash10-00di-9220000000-a032ac9bac05d35c0263	Not Available	View Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum	Not Available	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-03di-0900000000-c5992eb4929bea0caa6f	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-03di-0920000000-3876fd4c2b58b792ae17	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-03di-0900000000-f62223c14a643777c106	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-03di-0900000000-d29595def934a65b4542	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-03di-0900000000-d18ea65f7c9d27efe5a0	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-03di-0900000000-12b2f23aca41aae72df5	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-03k9-1900000000-a0b74f1e7d9731547b09	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-03di-0910000000-43f63558efefe96b63ae	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-03di-0900000000-be8426feb3ff30050b90	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-03di-0900000000-8d1371b31d25aec0cee0	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-03di-0900000000-1256ac189274e190c88c	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-03di-0900000000-47d5448d947385bed9c7	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-03k9-1900000000-4ec7a7637e246c888d26	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-03di-0900000000-c301b58f9c0c131183b2	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-03di-0900000000-6e3b873d7e2075a6278c	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-03k9-1900000000-4ec7a7637e246c888d26	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-03di-0900000000-918b0eab0ce642175a9f	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-03di-0910000000-929b2d2c324a765328bd	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-03di-0900000000-47d5448d947385bed9c7	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-03di-0900000000-c301b58f9c0c131183b2	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-03di-0900000000-6e3b873d7e2075a6278c	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-03di-0900000000-1256ac189274e190c88c	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-03di-0900000000-c5992eb4929bea0caa6f	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-03k9-1900000000-a0b74f1e7d9731547b09	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-03di-0900000000-d18ea65f7c9d27efe5a0	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-03di-0900000000-12b2f23aca41aae72df5	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-03di-0900000000-7a070b99636431c633a4	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-03di-0920000000-fcad4bdb1d1ef1addd04	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-03di-0900000000-c94a12035214125e271c	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-03di-0900000000-e9b0d6314e8f95d8097f	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-03di-0900000000-ce9e487c39d285dfd379	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-022i-3900000000-454f9873ef438032c22a	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-03di-0900000000-da5ca0735c3a473426d2	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-03di-0900000000-d29595def934a65b4542	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-03di-0900000000-f62223c14a643777c106	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-03k9-0900000000-b98d3537cefd0dc56ae8	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-00di-0090000000-65c3456a76900ddcdf95	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-0fk9-0090000000-a8795ac49517985dafc3	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-0002-3930000000-16586343387743da8ed4	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-014i-0190000000-fb5ffe9f68edbfbd545d	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-014i-0390000000-c164f3f3990c2d027cdf	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-0fkc-3930000000-173e8bfc603e92ae9c83	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-01b9-0590000000-838e47827204f23917b3	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-0g4i-0590000000-c53a0a7fe0fd9f362d5d	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-001i-8900000000-b22f389a751f6579fc34	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-0fk9-0090000000-2bd9c031c0459158cf07	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-0uk9-4390000000-5285ff61921dfeecd1fe	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-0002-2900000000-ef44d9355208ee602564	Not Available	View Spectrum
MS	MS Spectrum	splash10-03di-2920000000-124d727a3888770108bf	Not Available	View Spectrum

Toxicity Profile

Mechanism of Toxicity

2,4-Dichlorophenoxyacetic acid is a strong oxidant and is known to cause lipid peroxidation and the generation of free radicals that can modify lipids and proteins. It is also known to inhibit glutathione S transferase which leads to a depletion of ATP, NADPH and glutathione (5, 6). These actions can cause cell toxicity and apopotosis among metabolically active cells. Some of the endocrine effects of 2,4-D may be mediated by the 2,4-D mediated displacement of sex hormones from the sex hormone binding globulin or the 2,4-D mediated blocking or OAT6 transport proteins that are needed for the transport of functional organic ions and dicarboxylates (including estrone sulfate).

Carcinogenicity (IARC Classification)

2B, possibly carcinogenic to humans. (10)

Minimum Risk Level

Not Available

Symptoms

Symptoms of acute oral exposure include vomiting, diarrhea, headache, confusion, aggressive or bizarre behavior, hypotension and muscle twitching. Skeletal muscle injury and renal failure may also occur. Prolonged dermal exposure may include skin irritation, whereas prolonged inhalation exposure may lead to coughing and burning sensations in the upper respiratory tract and chest.

Treatment

The general treatment of acute chlorophenoxy herbicide poisoning consists of decontamination of the gastrointestinal tract, resuscitation and supportive care. For severe, acute oral poisoning by 2,4-D forced alkaline diuresis appears to be most effective (9). Forced alkaline diuresis is often used to increase the excretion of acidic drugs like salicylates and phenobarbitone. For forced alkaline diuresis, a diuretic like furosemide is given intravenously and sodium bicarbonate is added to the infusion fluid to make blood and, in turn, urine alkaline. Potassium replacement becomes of utmost importance during the process because potassium is usually lost in urine. If blood levels of potassium are depleted below normal levels, then hypokalemia occurs, which promotes bicarbonate ion retention and prevents bicarbonate excretion, thus interfering with the alkalinization of the urine.

Toxicity Values

Toxicity Value	Unit	Value Range	Organism	Dose Descriptor	Route of Exposure	Predicted or Experimental	Reference
1400.0	mg/kg	Not Available	Rabbit	LD50	Dermal	experimental	T14
469.0	mg/kg	Not Available	Guinea pig	LD50	Oral	experimental	Not Available
639.0	mg/kg	Not Available	Rat	LD50	Oral	experimental	L1982
138.0	mg/kg	Not Available	Mouse	LD50	Oral	experimental	L1982

Health Effects

Health Effect	Relationship	Direction	Reference
cancer	associated_with	Not Available	PMC4782969
Prostate cancer	associated_with	Not Available	PMC3734498
non-Hodgkin lymphoma	associated_with	Not Available	PMC3734498

Exposure Sources

Source ID	Source	Sector	Reference
10	Insecticides	Agriculture & land management	Not Available
115	Drinking water	Drinking water & water supply	Not Available
233	Brushes	Personal care & cosmetics	Not Available
495	Ceilings	Building & Construction	Not Available
496	Fencing	Building & Construction	Not Available
497	Floors	Building & Construction	Not Available
499	Roofs	Building & Construction	Not Available
500	Stairs And Ramps	Building & Construction	Not Available
501	Sunshades Awnings Or Outside Screens	Building & Construction	Not Available
502	Sunshades Awnings Or Outside Screens	Building & Construction	Not Available
503	Tents Or Canopies	Building & Construction	Not Available
504	Adjustable Resistors	Electrical & Electronic Equipment	Not Available
505	Amplifiers	Electrical & Electronic Equipment	Not Available
506	Antennas	Electrical & Electronic Equipment	Not Available
507	Auxiliary Devices	Electrical & Electronic Equipment	Not Available
508	Coils	Electrical & Electronic Equipment	Not Available
509	Colour Television Systems	Electrical & Electronic Equipment	Not Available
510	Communication Cables Or Conductors	Electrical & Electronic Equipment	Not Available
511	Conductors Or Conductive Bodies Characterised By The Conductive Materials	Electrical & Electronic Equipment	Not Available
512	Contacts	Electrical & Electronic Equipment	Not Available
513	Cores Yokes Or Armatures	Electrical & Electronic Equipment	Not Available
514	Discharge Lamps	Electrical & Electronic Equipment	Not Available
516	Electric Hearing Aids	Electrical & Electronic Equipment	Not Available
517	Electric Switches	Electrical & Electronic Equipment	Not Available
519	Electrodes	Electrical & Electronic Equipment	Not Available
520	Emergency Protective Devices	Electrical & Electronic Equipment	Not Available
521	Fixed Capacitors And Their Manufacture	Electrical & Electronic Equipment	Not Available
524	Hybrid Capacitors	Electrical & Electronic Equipment	Not Available
525	Line Transmission Systems	Electrical & Electronic Equipment	Not Available
526	Loudspeakers	Electrical & Electronic Equipment	Not Available
527	Magnets	Electrical & Electronic Equipment	Not Available
529	Power Cables	Electrical & Electronic Equipment	Not Available
530	Radio Transmission Systems	Electrical & Electronic Equipment	Not Available
531	Relays	Electrical & Electronic Equipment	Not Available
532	Selectors	Electrical & Electronic Equipment	Not Available
533	Sparking Plugs	Electrical & Electronic Equipment	Not Available
535	Superconducting Magnets And Superconducting Coils	Electrical & Electronic Equipment	Not Available
536	Superconductive Or Hyperconductive Conductors Cables Or Transmission Lines	Electrical & Electronic Equipment	Not Available
537	Television Systems	Electrical & Electronic Equipment	Not Available
538	Thin Magnetic Films	Electrical & Electronic Equipment	Not Available
539	Video Games	Electrical & Electronic Equipment	Not Available
544	Fermentation Processes For Beer	Food, food processing & cookware	Not Available
545	Food Preservation	Food, food processing & cookware	Not Available
547	Preparation Of Malt	Food, food processing & cookware	Not Available
549	Preparation Of Wine Or Sparkling Wine	Food, food processing & cookware	Not Available
550	Preparation Of Wort	Food, food processing & cookware	Not Available
552	Processing Meats	Food, food processing & cookware	Not Available
555	Bleaching Agents	Household cleaning & consumer products	Not Available
556	Cigar Cigarettes	Household cleaning & consumer products	Not Available
560	Other Smoking Requisites	Household cleaning & consumer products	Not Available
561	Perfumes Within Detergents And Soaps	Household cleaning & consumer products	Not Available
562	Pipe Accessories	Household cleaning & consumer products	Not Available
563	Soap Detergents	Household cleaning & consumer products	Not Available
564	Soap Dispensers	Household cleaning & consumer products	Not Available
566	Tobacco Pipes	Household cleaning & consumer products	Not Available
568	Tobacco Product Moisture Control	Household cleaning & consumer products	Not Available
569	Tobacco Smoke Filters	Household cleaning & consumer products	Not Available
572	Credit Card Holders	Household items	Not Available
575	Rosaries	Household items	Not Available
578	Making Cigars	Industrial manufacturing & chemical processing	Not Available
579	Manufacture Of Iron Or Steel	Industrial manufacturing & chemical processing	Not Available
580	Manufacture Preparation Of Tobacco Products	Industrial manufacturing & chemical processing	Not Available
581	Paper Making Machines	Industrial manufacturing & chemical processing	Not Available
583	Anchoring Equipment	Marine, shipping & aquaculture	Not Available
584	Buoys	Marine, shipping & aquaculture	Not Available
592	Marine Propulsion Or Steering	Marine, shipping & aquaculture	Not Available
596	Acaricides	Agriculture & land management	Not Available
597	Chemosterilants	Agriculture & land management	Not Available
598	Fertiliser Distributors	Agriculture & land management	Not Available
600	Herbicides And Algicides	Agriculture & land management	Not Available
601	Lawn Mowers	Agriculture & land management	Not Available
602	Molluscicides	Agriculture & land management	Not Available
603	Nematocides	Agriculture & land management	Not Available
604	Pest Attractants	Agriculture & land management	Not Available
605	Pest Repellants	Agriculture & land management	Not Available
606	Plant Growth Regulators	Agriculture & land management	Not Available
607	Rodenticides(1)	Agriculture & land management	Not Available
608	Rodenticides	Agriculture & land management	Not Available
609	Aftershave	Personal care & cosmetics	Not Available
610	Aftersun Products	Personal care & cosmetics	Not Available
611	Anti Perspirants Or Body Deoderants	Personal care & cosmetics	Not Available
612	Body Washing Or Cleaning Implements	Personal care & cosmetics	Not Available
613	Depilatories	Personal care & cosmetics	Not Available
614	Essential Oils Or Perfumes	Personal care & cosmetics	Not Available
615	Eye Makeup Products	Personal care & cosmetics	Not Available
616	Face Mask Cosmetics	Personal care & cosmetics	Not Available
617	Lip Care Products	Personal care & cosmetics	Not Available
618	Lip Makeup Products	Personal care & cosmetics	Not Available
619	Manicure Pedicure	Personal care & cosmetics	Not Available
620	Card Games	Recreation & sports surfaces	Not Available
630	Toys	Recreation & sports surfaces	Not Available
632	Apparel	Textiles, leather & furnishings	Not Available
633	Azo Dyes	Textiles, leather & furnishings	Not Available
634	Buckles	Textiles, leather & furnishings	Not Available
638	Decorating Textiles	Textiles, leather & furnishings	Not Available
642	Footwear	Textiles, leather & furnishings	Not Available
643	Headwear	Textiles, leather & furnishings	Not Available
650	Purses Luggage Hand Bags	Textiles, leather & furnishings	Not Available
651	Purses Money Bags Wallets	Textiles, leather & furnishings	Not Available
652	Ropes	Textiles, leather & furnishings	Not Available
653	Sewing	Textiles, leather & furnishings	Not Available
655	Slide Fasteners	Textiles, leather & furnishings	Not Available
657	Surface Finishing Of Leather	Textiles, leather & furnishings	Not Available
658	Touch Fasteners	Textiles, leather & furnishings	Not Available
659	Transfer Printing	Textiles, leather & furnishings	Not Available
661	Umbrellas	Textiles, leather & furnishings	Not Available
662	Yarns Or Threads	Textiles, leather & furnishings	Not Available
663	Sanitary Equipment	Wastewater, sanitation & biosolids	Not Available

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this synthetic chemical

Targets

Structure	Protein	UniProt ID	Organism	Relationship	Details
Click to view 3D structure	Prostaglandin E2 receptor EP2 subtype	P43116	Humans	Predicted (SEA)	9.73115
Click to view 3D structure	Cytochrome P450 3A4	P08684	Humans	Predicted (SEA)	393.061
Click to view 3D structure	Thromboxane A2 receptor	P21731	Humans	Predicted (SEA)	11.5995
Click to view 3D structure	Enoyl-acyl-carrier protein reductase	Q965D5	Plasmodium falciparum	Predicted (SEA)	4.51525
Click to view 3D structure	Cytochrome P450 2C19	P33261	Humans	Predicted (SEA)	173.215
Click to view 3D structure	Cytochrome P450 2D6	P10635	Humans	Predicted (SEA)	322.218
Click to view 3D structure	Cytochrome P450 1A2	P05177	Humans	Predicted (SEA)	237.907
Click to view 3D structure	Carbonic anhydrase 2	P00918	Humans	Predicted (SEA)	174.849
Click to view 3D structure	Aldo-keto reductase family 1 member B1	P07943	Rattus norvegicus	Predicted (SEA)	21.8756
Click to view 3D structure	Enoyl-acyl carrier reductase	Q6UCJ9	Toxoplasma gondii	Predicted (SEA)	0.778492
Click to view 3D structure	Streptokinase A	P10520	Streptococcus pyogenes serotype M1	Predicted (SEA)	73.6454
Click to view 3D structure	Coagulation factor VIII	P00451	Humans	Predicted (SEA)	1.86838
Click to view 3D structure	Carbonic anhydrase 12	O43570	Humans	Predicted (SEA)	173.37
Click to view 3D structure	Phospholipase A2, membrane associated	P14555	Humans	Predicted (SEA)	8.32987
Click to view 3D structure	Phospholipase A2	P04054	Humans	Predicted (SEA)	5.99439
Click to view 3D structure	Prostaglandin E2 receptor EP1 subtype	P34995	Humans	Predicted (SEA)	27.5586
Click to view 3D structure	Small ubiquitin-related modifier 1	P63165	Humans	Predicted (SEA)	21.0971
Click to view 3D structure	Transthyretin	P02766	Humans	Predicted (SEA)	24.5225
Click to view 3D structure	Metabotropic glutamate receptor 4	P31423	Rattus norvegicus	Predicted (SEA)	20.3186
Click to view 3D structure	Prostaglandin E2 receptor EP3 subtype	P43115	Humans	Predicted (SEA)	30.8283
Click to view 3D structure	Prostaglandin D2 receptor 2	Q9Y5Y4	Humans	Predicted (SEA)	2.17978
Click to view 3D structure	Cytochrome P450 2C9	P11712	Humans	Predicted (SEA)	71.777
Click to view 3D structure	Prostaglandin D2 receptor	Q13258	Humans	Predicted (SEA)	4.12601
Click to view 3D structure	Sigma intracellular receptor 2	Q8VD00	Mus musculus	Predicted (SEA)	0.311397
Click to view 3D structure	Prostaglandin D2 receptor 2	Q9Z2J6	Mus musculus	Predicted (SEA)	1.71268
Click to view 3D structure	Glutathione S-transferase P	P09211	Humans	Known	Not Available
Click to view 3D structure	Glutathione peroxidase 2	P18283	Humans	Known	Not Available
Click to view 3D structure	Sex hormone-binding globulin	P04278	Humans	Known	Not Available
Click to view 3D structure	Nuclear receptor subfamily 1 group I member 2	O75469	Humans	Known	Not Available
Click to view 3D structure	Cytochrome P450 2B6	P20813	Humans	Known	Not Available
Click to view 3D structure	Interleukin-1 alpha	P01583	Humans	Known	Not Available
Click to view 3D structure	Urokinase plasminogen activator surface receptor	Q03405	Humans	Known	Not Available