Mirex (CED0007792)

Record Information
Version1.0
Creation Date2009-06-09 17:20:39 UTC
Update Date2026-08-17 20:56:54 UTC
SynCED IDCED0007792
Secondary Accession Numbers
  • CHEM000740
  • T3D0855
Identification
Common NameMirex
ClassSmall Molecule
Description
Mirex belongs to the monoterpenoids, a subclass of prenol lipids within the organic compounds. With an average molecular weight of 545.54 g/mol, Mirex is a heavy molecule. This exogenous compound has the formula C10Cl12 and exists as a solid at room temperature. It has been utilized as an industrial organochlorine insecticide (PMC6842667 ), a pesticide for industrial and biological use (PMC7614514 , PMC9908711 ), and an industrial flame retardant (PMC7830114 ). It is classified as a persistent organic pollutant (PMC7614514 , PMC9908711 ) and has been used in polyamide plastics. Recorded sources of the compound include food processing and cookware, such as the preparation of malt and fermentation processes for beer, as well as electrical and electronic equipment, including antennas, communication cables or conductors, coils, cores yokes or armatures, and auxiliary devices. Mirex acts on 32 recorded protein targets. It inhibits Ca2+ and Mg2+ ATPase and Na+/K+ ATPase, including the alpha-1, alpha-2, alpha-3, and gamma subunits, which disrupts calcium transport across membranes and leads to intracellular free calcium ion accumulation, neurotransmitter release, and the propagation of stimuli throughout the central nervous system. Additionally, it antagonizes the neurotransmitter gamma-aminobutyric acid (GABA) at GABA-A receptors, including the alpha-1, alpha-2, alpha-3, and alpha-4 subunits, blocking chloride ion uptake and causing central nervous system hyperexcitability. Mirex also causes endocrine disruption in humans by binding to and inhibiting estrogen receptor alpha (ESR1) and beta (ESR2). Health effects associated with the compound include endometriosis (PMC9908711 ) and hyperactivity (PMC8692415 ).
Contaminant Type
  • Human Neurotoxin
  • Metabolite
  • Organic Compound
  • Organochloride
  • Pesticide
  • Pollutant
  • Synthetic Compound
Chemical Structure
Synonyms
ValueSource
1,2,3,4,5,5,6,7,8,9,10,10-Dodecachloropentacyclo[5.3.0.0(2,6).0(3,9).0(4,8)]decaneChEBI
CG-1283ChEBI
DechloraneChEBI
Dodecachlorooctahydro-1,3,4-metheno-2H-cyclobuta[CD]pentaleneChEBI
PerchlorodihomocubaneChEBI
Perchloropentacyclo[5.2.1.0(2,6).0(3,9).0(5,8)]decaneChEBI
PerchloropentacyclodecaneChEBI
Chemical FormulaC10Cl12
Average Molecular Mass545.543 g/mol
Monoisotopic Mass539.626 g/mol
CAS Registry Number2385-85-5
IUPAC Namedodecachloropentacyclo[5.3.0.0²,⁶.0³,⁹.0⁴,⁸]decane
Traditional Namemirex
SMILESClC12C3(Cl)C4(Cl)C5(Cl)C(Cl)(C1(Cl)C4(Cl)Cl)C2(Cl)C(Cl)(Cl)C35Cl
InChI IdentifierInChI=1S/C10Cl12/c11-1-2(12)7(17)4(14)3(13,5(1,15)9(7,19)20)6(1,16)10(21,22)8(2,4)18
InChI KeyGVYLCNUFSHDAAW-UHFFFAOYSA-N
Chemical Taxonomy
Description Belongs to the class of organic compounds known as monoterpenoids. Monoterpenoids are compounds containing a chain of two isoprene units.
KingdomOrganic compounds
Super ClassLipids and lipid-like molecules
ClassPrenol lipids
Sub ClassMonoterpenoids
Direct ParentMonoterpenoids
Alternative Parents
Substituents
  • Norbornane monoterpenoid
  • Monoterpenoid
  • Hydrocarbon derivative
  • Organochloride
  • Organohalogen compound
  • Alkyl halide
  • Alkyl chloride
  • Aliphatic homopolycyclic compound
Molecular FrameworkAliphatic homopolycyclic compounds
External Descriptors
Biological Properties
StatusDetected and Not Quantified
OriginExogenous
Cellular Locations
  • Membrane
Biofluid LocationsNot Available
Tissue LocationsNot Available
ApplicationsNot Available
Biological Roles
Chemical Roles
Organoleptic EffectsNot Available
Physical Properties
StateSolid
AppearanceWhite crystals.
Experimental Properties
PropertyValue
Melting Point485°C
Boiling PointNot Available
Solubility8.5e-05 mg/mL at 25°C [YALKOWSKY,SH & HE,Y (2003)]
Predicted Properties
PropertyValueSource
Water Solubility0.00022 g/LALOGPS
logP6.61ALOGPS
logP7.63ChemAxon
logS-6.4ALOGPS
Physiological Charge0ChemAxon
Hydrogen Acceptor Count0ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area0 ŲChemAxon
Rotatable Bond Count0ChemAxon
Refractivity92.36 m³·mol⁻¹ChemAxon
Polarizability39.41 ųChemAxon
Number of Rings5ChemAxon
BioavailabilityNoChemAxon
Rule of FiveNoChemAxon
Ghose FilterNoChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleNoChemAxon
Spectra
Spectra
Spectrum TypeDescriptionSplash KeyDeposition DateView
Predicted GC-MSPredicted GC-MS Spectrumsplash10-0005-0000090000-3558aeafbee19bed3d18Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-0006-0000090000-fa7b7b7c7b445363fb85Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-0006-0000090000-fa7b7b7c7b445363fb85Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-0006-0000090000-fa7b7b7c7b445363fb85Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-000i-0000090000-1eb028a3dd3ed0f97602Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-000i-0000090000-1eb028a3dd3ed0f97602Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-000i-0000090000-1eb028a3dd3ed0f97602Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-0006-0000090000-717ca6e697afa5fefef6Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-0006-0000090000-717ca6e697afa5fefef6Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-0006-0000090000-717ca6e697afa5fefef6Not AvailableView Spectrum
MSMS Spectrumsplash10-00di-0191000000-15214d51523ee39f2af2Not AvailableView Spectrum
Toxicity Profile
Toxicity Values
Toxicity ValueOrganismDose DescriptorRoute of ExposurePredicted or ExperimentalToxicity RatingReference
306.0 mg/kg RatLD50OralexperimentalNot Available6
800.0 mg/kg RabbitLD50SubcutaneousexperimentalNot Available6
2000.0 mg/kg RabbitLD50DermalexperimentalNot Available7
365.0 mg/kg RatLD50IntraperitonealexperimentalNot Available7
228.0 Log mg/kg [130:410]RatLD50oralpredictedNot AvailableNot Available
25.0 mg/kg-day MouseLOELoralexperimentalNot AvailableECOTOX - EPA ORD
25.0 mg/kg-day MouseLOELoralexperimentalNot AvailableECOTOX - EPA ORD
1.5 mg/kg-day MouseLOELoralexperimentalNot AvailableECOTOX - EPA ORD
6.0 mg/kg-day MouseLOELoralexperimentalNot AvailableECOTOX - EPA ORD
3.0 mg/kg-day MouseNOELoralexperimentalNot AvailableECOTOX - EPA ORD
6.0 mg/kg-day MouseNOELoralexperimentalNot AvailableECOTOX - EPA ORD
9.0 mg/kg-day MouseLOELoralexperimentalNot AvailableECOTOX - EPA ORD
30.0 ppm RatLOELoralexperimentalNot AvailableECOTOX - EPA ORD
20.0 ppm RatLOELoralexperimentalNot AvailableECOTOX - EPA ORD
30.0 ppm RatNOELoralexperimentalNot AvailableECOTOX - EPA ORD
30.0 ppm RatNOELoralexperimentalNot AvailableECOTOX - EPA ORD
10.0 ppm RatLOELoralexperimentalNot AvailableECOTOX - EPA ORD
10.0 ppm RatNOELoralexperimentalNot AvailableECOTOX - EPA ORD
40.0 ppm RatLOELoralexperimentalNot AvailableECOTOX - EPA ORD
10.0 ppm RatLOELoralexperimentalNot AvailableECOTOX - EPA ORD
40.0 ppm RatLOELoralexperimentalNot AvailableECOTOX - EPA ORD
20.0 ppm RatLOELoralexperimentalNot AvailableECOTOX - EPA ORD
20.0 ppm RatNOELoralexperimentalNot AvailableECOTOX - EPA ORD
10.0 ppm RatNOELoralexperimentalNot AvailableECOTOX - EPA ORD
120.0 mg/kg-day MouseNOELoralexperimentalNot AvailableECOTOX - EPA ORD
10.0 mg/kg-day MouseNOELoralexperimentalNot AvailableECOTOX - EPA ORD
10.0 mg/kg-day MouseLOELoralexperimentalNot AvailableECOTOX - EPA ORD
10.0 mg/kg-day MouseLOELoralexperimentalNot AvailableECOTOX - EPA ORD
50.0 mg/kg-day MouseLOELoralexperimentalNot AvailableECOTOX - EPA ORD
10.0 mg/kg-day RatNOELoralexperimentalNot AvailableECOTOX - EPA ORD
2.5 mg/kg-day RatLOELoralexperimentalNot AvailableECOTOX - EPA ORD
1.0 mg/kg-day RatNOELoralexperimentalNot AvailableECOTOX - EPA ORD
9.5 mg/kg-day RatLOELoralexperimentalNot AvailableECOTOX - EPA ORD
19.0 mg/kg-day RatNOELoralexperimentalNot AvailableECOTOX - EPA ORD
19.0 mg/kg-day RatLOELoralexperimentalNot AvailableECOTOX - EPA ORD
7.0 mg/kg-day RatLOELoralexperimentalNot AvailableECOTOX - EPA ORD
5.0 mg/kg-day RatNOELoralexperimentalNot AvailableECOTOX - EPA ORD
38.0 mg/kg-day RatNOELoralexperimentalNot AvailableECOTOX - EPA ORD
7.0 mg/kg-day RatLOELoralexperimentalNot AvailableECOTOX - EPA ORD
5.0 mg/kg-day RatNOELoralexperimentalNot AvailableECOTOX - EPA ORD
9.5 mg/kg-day RatLOELoralexperimentalNot AvailableECOTOX - EPA ORD
7.0 mg/kg-day RatNOELoralexperimentalNot AvailableECOTOX - EPA ORD
38.0 mg/kg-day RatNOELoralexperimentalNot AvailableECOTOX - EPA ORD
9.5 mg/kg-day RatNOELoralexperimentalNot AvailableECOTOX - EPA ORD
7.0 mg/kg-day RatNOELoralexperimentalNot AvailableECOTOX - EPA ORD
6.0 mg/kg-day RatLOELoralexperimentalNot AvailableECOTOX - EPA ORD
6.0 mg/kg-day RatLOELoralexperimentalNot AvailableECOTOX - EPA ORD
Toxicity / Toxin ClassNot Available
Mechanism of ToxicityMirex inhibits sodium/potassium-transporting ATPases, producing neurotoxic effects and impairing energy-dependent cellular processes. (1)
Carcinogenicity (IARC Classification)2B, possibly carcinogenic to humans. (3)
Minimum Risk LevelChronic Oral: 0.0008 mg/kg/day (2)
SymptomsNot Available
TreatmentNot Available
Health Effects
Health EffectRelationshipDirectionDescriptionReference
polycystic ovary syndromeAssociated With?increaseA syndrome characterized by hyperandrogenism, polycystic ovaries, hirsutism, oligomenorrhea or amenorrhea, anovulation and excessive body weight. (DO)PMC13466750
diabetes mellitusAssociated With?Not AvailableA glucose metabolism disease characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both. (DO)PMC3701910 , PMC5741159
hypoglycemiaAssociated With?Not AvailableA disorder characterized by laboratory test results that indicate a low concentration of glucose in the blood. (NCI CTCAE)PMC11964802
EndometriosisAssociated With?Not AvailableEndometriosis is a condition that affects women in which cells similar to those in the endometrium, the layer of tissue that normally covers the inside of the uterus, grow outside the uterus (mainly in the ovaries and fallopian tubes). The main symptoms are pelvic pain and infertility, although 20-25% of women are asymptomatic. Pain during sexual intercourse is also common. Other symptoms include diarrhea or constipation, chronic fatigue, nausea and vomiting, headaches, low-grade fevers, heavy and/or irregular periods, and hypoglycemia. Endometriosis is a common condition. About 6–10% of women are affected. Endometriosis is most common in those in their thirties and forties; however, it can begin in girls as early as eight years old.PMC9908711
EndometriosisAssociated With?increaseEndometriosis is a condition that affects women in which cells similar to those in the endometrium, the layer of tissue that normally covers the inside of the uterus, grow outside the uterus (mainly in the ovaries and fallopian tubes). The main symptoms are pelvic pain and infertility, although 20-25% of women are asymptomatic. Pain during sexual intercourse is also common. Other symptoms include diarrhea or constipation, chronic fatigue, nausea and vomiting, headaches, low-grade fevers, heavy and/or irregular periods, and hypoglycemia. Endometriosis is a common condition. About 6–10% of women are affected. Endometriosis is most common in those in their thirties and forties; however, it can begin in girls as early as eight years old.PMC13466750 , PMC5747985
hyperactivityAssociated With?Not AvailableA condition characterized by increased movement, impulsive actions, and a shorter attention span, and being easily distracted.PMC8692415
hepatic steatosisAssociated With?Not AvailableNot AvailablePMC5664782
cryptorchidismAssociated With?Not AvailableNot AvailablePMC6029725
hypospadiasAssociated With?Not AvailableNot AvailablePMC6029725
autoimmune diseaseAssociated With?Not AvailableAn autoimmune disease is a condition arising from an abnormal immune response to a functioning body part. There are at least 80 types of autoimmune diseases. Nearly any body part can be involved. Common symptoms include low grade fever and feeling tired. Some autoimmune diseases such as lupus run in families, and certain cases may be triggered by infections or other environmental factors. Some common diseases that are generally considered autoimmune include celiac disease, diabetes mellitus type 1, Graves' disease, inflammatory bowel disease, multiple sclerosis, psoriasis, rheumatoid arthritis, and systemic lupus erythematosus. About 24 million (7%) people in the United States are affected by an autoimmune disease. Women are more commonly affected than men.PMC2813917
pancreatic adenocarcinomaAssociated With?increaseNot AvailablePMC11497671
Congenital AbnormalitiesAssociated With?increaseNot AvailablePMC8530230
hyperlipidemiaAssociated With?Not AvailableNot AvailablePMC11964802
Exposure Sources
Source IDSourceSectorReference
CEDs000010Insecticides?Insecticides are synthetic chemicals designed to control or eliminate insect pests that threaten crops and other agricultural products.Agriculture & land managementPubChem
CEDs000013Soil?Soil serves as a critical medium for plant growth and sustains various ecological functions; however, it can become a reservoir for synthetic chemical contamination.Agriculture & land managementPMC7056722 , PMC7056722
CEDs000070Stormwater runoff?Stormwater runoff refers to the flow of rainwater or melted snow that does not soak into the ground and instead collects pollutants as it travels over impervious surfaces such as roads and parking lots.Automotive & urban infrastructurePubChem
CEDs000506Antennas?Antennas, commonly used in communication technologies, can be a source of synthetic chemical contamination through the materials and coatings used in their construction.Electrical & Electronic EquipmentPubChem
CEDs000507Auxiliary Devices?Auxiliary devices, such as capacitors, transformers, and circuit breakers, are integral components in various electronic systems.Electrical & Electronic EquipmentPubChem
CEDs000508Coils?Coils are components used in various electrical and electronic applications, such as transformers, inductors, and motors.Electrical & Electronic EquipmentPubChem
CEDs000510Communication Cables Or Conductors?Communication cables or conductors are essential components in the transmission of data and signals in various applications, including telecommunications and networking.Electrical & Electronic EquipmentPubChem
CEDs000511Conductors Or Conductive Bodies Characterised By The Conductive Materials?Conductors, or conductive bodies, are materials that allow the flow of electrical current, typically made from metals such as copper, aluminum, or silver.Electrical & Electronic EquipmentPubChem
CEDs000513Cores Yokes Or Armatures?Cores, yokes, or armatures are components commonly found in electrical devices, used to facilitate the magnetic and electrical functions within motors, transformers, and generators.Electrical & Electronic EquipmentPubChem
CEDs000514Discharge Lamps?Discharge lamps, including fluorescent and high-intensity discharge (HID) lamps, are commonly used for lighting applications due to their energy efficiency and brightness.Electrical & Electronic EquipmentPubChem
CEDs000518Electrically Stimulated Smoking Devices?Electrically stimulated smoking devices, commonly known as e-cigarettes or vape pens, utilize electrical components to heat a liquid solution, often containing nicotine, flavorings, and other additives, to produce an aerosol for inhalation.Electrical & Electronic EquipmentPubChem
CEDs000519Electrodes?Electrodes, used in various electrical and electronic applications, can be a source of synthetic chemical contamination due to the materials from which they are constructed and the processes involved in their manufacturing.Electrical & Electronic EquipmentPubChem
CEDs000521Fixed Capacitors And Their Manufacture?Fixed capacitors are passive electronic components used to store and release electrical energy, playing a critical role in various circuits.Electrical & Electronic EquipmentPubChem
CEDs000524Hybrid Capacitors?Hybrid capacitors are energy storage devices that combine the properties of electrolytic and supercapacitors, utilizing a combination of electrochemical principles to achieve higher energy density and power density.Electrical & Electronic EquipmentPubChem
CEDs000527Magnets?Magnets, commonly used in various electrical and electronic applications, can be a source of synthetic chemical contamination due to the materials used in their production.Electrical & Electronic EquipmentPubChem
CEDs000529Power Cables?Power cables are used to transmit electrical energy and are typically composed of conductive materials, insulation, and protective coatings.Electrical & Electronic EquipmentPubChem
CEDs000544Fermentation Processes For Beer?Fermentation processes for beer involve the conversion of sugars into alcohol and carbon dioxide by yeast.Food, food processing & cookwarePubChem
CEDs000545Food Preservation?Food preservation often involves the use of synthetic chemicals, such as preservatives, flavor enhancers, and color additives, to extend shelf life and enhance the sensory qualities of food products.Food, food processing & cookwarePubChem
CEDs000547Preparation Of Malt?Malt preparation involves the germination and drying of cereal grains, primarily barley, to produce malt for brewing and food products.Food, food processing & cookwarePubChem
CEDs000561Perfumes Within Detergents And Soaps?Perfumes within detergents and soaps are synthetic fragrance compounds added to enhance the sensory experience of cleaning products.Household cleaning & consumer productsPubChem
CEDs000580Manufacture Preparation Of Tobacco Products?The manufacture and preparation of tobacco products involve various processes that can result in the introduction of synthetic chemicals into the environment.Industrial manufacturing & chemical processingPubChem
CEDs000583Anchoring Equipment?Anchoring equipment, commonly used in marine applications, can be a source of synthetic chemical contamination due to the materials and coatings utilized in their manufacturing.Marine, shipping & aquaculturePubChem
CEDs000596Acaricides?Acaricides are synthetic chemicals specifically designed to target and control mite populations that can damage crops and plants.Agriculture & land managementPubChem
CEDs000597Chemosterilants?Chemosterilants are synthetic chemicals designed to induce sterility in target pest populations, thereby controlling their reproduction and mitigating damage to crops.Agriculture & land managementPubChem
CEDs000598Fertiliser Distributors?Fertiliser distributors play a critical role in the supply of synthetic fertilizers, which are widely used to enhance soil fertility and crop yield.Agriculture & land managementPubChem
CEDs000600Herbicides And Algicides?Herbicides and algicides are synthetic chemicals primarily used to control unwanted plants and algae in various environments.Agriculture & land managementPubChem
CEDs000601Lawn Mowers?Lawn mowers, particularly those powered by gasoline, can be a source of synthetic chemical contamination due to the combustion of fossil fuels and the use of engine oils.Agriculture & land managementPubChem
CEDs000602Molluscicides?Molluscicides are synthetic chemicals specifically designed to control and eliminate mollusks, such as snails and slugs, which can be detrimental to crops and agricultural productivity.Agriculture & land managementPubChem
CEDs000603Nematocides?Nematocides are synthetic chemicals specifically designed to control nematodes, which are microscopic roundworms that can cause significant damage to crops and plants.Agriculture & land managementPubChem
CEDs000604Pest Attractants?Pest attractants are synthetic chemicals designed to lure specific pests for monitoring or control purposes.Agriculture & land managementPubChem
CEDs000605Pest Repellants?Pest repellents, often formulated from synthetic chemicals, are widely used to protect crops from insect infestations and other pests.Agriculture & land managementPubChem
CEDs000606Plant Growth Regulators?Plant Growth Regulators (PGRs) are synthetic chemicals designed to influence the growth and development of plants.Agriculture & land managementPubChem
CEDs000607Rodenticides(1)?Rodenticides are synthetic chemicals specifically formulated to control rodent populations, serving as a crucial tool in managing pests that can damage crops and spread diseases.Agriculture & land managementPubChem
CEDs000608Rodenticides?Rodenticides are chemical substances specifically designed to control rodent populations by causing death through various mechanisms, including anticoagulation or neurotoxicity.Agriculture & land managementPubChem
CEDs000611Anti Perspirants Or Body Deoderants?Antiperspirants and body deodorants commonly contain synthetic chemicals such as aluminum compounds, parabens, and synthetic fragrances.Personal care & cosmeticsPubChem
CEDs000614Essential Oils Or Perfumes?Essential oils and perfumes are complex mixtures of volatile compounds derived from natural or synthetic sources, commonly used for their aromatic properties.Personal care & cosmeticsPubChem
CEDs000615Eye Makeup Products?Eye makeup products, including mascaras, eyeliners, and eyeshadows, often contain a variety of synthetic chemicals such as pigments, preservatives, and film-forming agents.Personal care & cosmeticsPubChem
CEDs000618Lip Makeup Products?Lip makeup products, such as lipsticks, lip glosses, and lip liners, often contain a variety of synthetic chemicals, including pigments, preservatives, and emollients.Personal care & cosmeticsPubChem
CEDs000632Apparel?Apparel production often involves the use of various synthetic chemicals, including dyes, finishing agents, and preservatives.Textiles, leather & furnishingsPubChem
CEDs000642Footwear?Footwear production often involves the use of various synthetic chemicals, such as adhesives, dyes, and treatments, which can contribute to environmental contamination.Textiles, leather & furnishingsPubChem
CEDs000653Sewing?Sewing processes often involve the use of various synthetic chemicals, which can become sources of contamination in the environment.Textiles, leather & furnishingsPubChem
CEDs000657Surface Finishing Of Leather?Surface finishing of leather often involves the use of various synthetic chemicals, including dyes, resins, and finishing agents.Textiles, leather & furnishingsPubChem
CEDs000662Yarns Or Threads?Yarns or threads used in textiles can be a source of synthetic chemical contamination due to the production processes and treatments they undergo.Textiles, leather & furnishingsPubChem
CEDs000665Fire Extinguishers?Fire extinguishers contain various synthetic chemicals designed to suppress flames and prevent the spread of fire.Fire suppression systems & agentsPubChem
CEDs000670Solid Fire Fighting Substances?Solid fire fighting substances, such as certain types of dry chemical powders, are used in fire suppression applications to extinguish flames and prevent fire spread.Fire suppression systems & agentsPubChem
CEDs000678Nitrogenous Fertilisers?Nitrogenous fertilizers are synthetic chemical compounds primarily used to enhance plant growth by supplying essential nitrogen, a crucial nutrient for photosynthesis and protein synthesis.Agriculture & land managementPubChem
CEDs000679Phosphatic Fertilisers?Phosphatic fertilizers are synthetic chemical products primarily composed of phosphorus, which is essential for plant growth.Agriculture & land managementPubChem
CEDs000684Cements?Cements are a composite material primarily used as a binding agent in construction applications, formed by the calcination of limestone and clay minerals at high temperatures.Building & ConstructionPubChem
CEDs000689Glass Fibres?Glass fibres are composed of fine strands of glass, commonly utilized for their tensile strength and lightweight properties.Building & ConstructionPubChem
CEDs000693Silica Glass?Silica glass, primarily composed of silicon dioxide (SiO2), is widely used in various applications, including windows, glass facades, and insulation materials.Building & ConstructionPubChem
CEDs000696Nanotechnology?Nanotechnology involves the manipulation of materials at the molecular or atomic level, typically within the range of 1 to 100 nanometers.Industrial manufacturing & chemical processingPubChem
CEDs000734Coating Compositions?Coating compositions, which include paints, sealants, and varnishes, are formulated with a variety of synthetic chemicals such as solvents, resins, pigments, and additives.Building & ConstructionPubChem
CEDs000735Explosives?Explosives are chemical compounds or mixtures designed to undergo rapid decomposition, releasing energy in the form of gas and heat.Defense & military infrastructurePubChem
CEDs000736Fuses?Fuses are safety devices designed to protect electrical circuits by breaking the circuit when excessive current flows through.Electrical & Electronic EquipmentPubChem
CEDs000738Cooling Circuit Water?Cooling circuit water is utilized in various industrial processes to absorb and dissipate heat generated during operations.Industrial manufacturing & chemical processingPubChem
CEDs000739Inks?Inks are complex mixtures composed of pigments or dyes, solvents, resins, and additives used primarily for printing and writing applications.Paper, pulp & fiber productsPubChem
CEDs000740Paper?Paper production involves the processing of wood fibers and the use of various chemicals, which can lead to synthetic chemical contamination.Paper, pulp & fiber productsPubChem
CEDs000741Pigment Pastes?Pigment pastes are concentrated dispersions of pigments used to impart color and properties to materials.Paper, pulp & fiber productsPubChem
CEDs000743Sludge Treatment?Sludge treatment involves the processing of waste materials generated from wastewater treatment plants, which often contain a variety of organic and inorganic substances.Wastewater, sanitation & biosolidsPubChem
CEDs000744Water, Wastewater, & Sewage Treatment?Water, wastewater, and sewage treatment processes are critical for managing and mitigating pollutants in water systems.Wastewater, sanitation & biosolidsPubChem
CEDs00804Karst SoilsAgriculture & land managementPMC13114842
CEDs00903Karst SoilAgriculture & land managementPMC8582917
CEDs01016OrchardAgriculture & land managementPMC8582917
CEDs01144FoodFood, food processing & cookwarePMC12777023
CEDs01148MilkFood, food processing & cookwarePMC7830114
CEDs01162Dairy ProductsFood, food processing & cookwarePMC7830114
CEDs01170EggsFood, food processing & cookwarePMC11525409
CEDs01171MeatFood, food processing & cookwarePMC12386664
CEDs01390ShellfishFood, food processing & cookwarePMC6684575
CEDs02257WatersAquatic systems & sedimentsPMC12999716
CEDs02264SedimentAquatic systems & sedimentsPMC7056722 , PMC7056722
CEDs02291Sediment SamplesAquatic systems & sedimentsPMC12999716
CEDs02387Sediment CoresAquatic systems & sedimentsPMC3751231
Pathways
0 pathwaysPathway Source: PathBank

No pathways found

No metabolic pathways have been associated with this synthetic chemical

Targets
StructureProteinUniProt IDOrganismRelationshipDetails
histidine kinase structureClick to view 3D structurehistidine kinaseO32393Arthrospira platensisPredicted (SEA)
Prediction Confidence Score
0.095
Applicability Domain
0.095 Low confidence
Statistical Significance
0.3238
Supporting Reference Compounds
1
E-value
2520.68
Click to view 3D structureGABA receptor subunitQ75NA5Musca domesticaPredicted (SEA)
Prediction Confidence Score
0.091
Applicability Domain
0.138 Low confidence
Statistical Significance
0.2306
Supporting Reference Compounds
2
E-value
1794.97
D(2) dopamine receptor structureClick to view 3D structureD(2) dopamine receptorP14416HumansPredicted (SEA)
Prediction Confidence Score
0.068
Applicability Domain
0.095 Low confidence
Statistical Significance
1.0
Supporting Reference Compounds
1103
E-value
7784.61
Sigma non-opioid intracellular receptor 1 structureClick to view 3D structureSigma non-opioid intracellular receptor 1Q99720HumansPredicted (SEA)
Prediction Confidence Score
0.066
Applicability Domain
0.095 Low confidence
Statistical Significance
1.0
Supporting Reference Compounds
562
E-value
7784.69
5-hydroxytryptamine receptor 1A structureClick to view 3D structure5-hydroxytryptamine receptor 1AP08908HumansPredicted (SEA)
Prediction Confidence Score
0.061
Applicability Domain
0.077 Low confidence
Statistical Significance
1.0
Supporting Reference Compounds
953
E-value
7784.61
5-hydroxytryptamine receptor 2A structureClick to view 3D structure5-hydroxytryptamine receptor 2AP28223HumansPredicted (SEA)
Prediction Confidence Score
0.06
Applicability Domain
0.077 Low confidence
Statistical Significance
1.0
Supporting Reference Compounds
955
E-value
7784.61
Click to view 3D structurePhenylalanine--tRNA ligase alpha subunitQ8P1K1Streptococcus pyogenes serotype M18 (strain MGAS8232)Predicted (SEA)
Prediction Confidence Score
0.06
Applicability Domain
0.06 Low confidence
Statistical Significance
0.9176
Supporting Reference Compounds
1
E-value
7143.13
Gamma-aminobutyric acid receptor subunit beta-3 structureClick to view 3D structureGamma-aminobutyric acid receptor subunit beta-3P28472HumansPredicted (SEA)
Prediction Confidence Score
0.06
Applicability Domain
0.138 Low confidence
Statistical Significance
0.9322
Supporting Reference Compounds
3
E-value
7257.03
5-hydroxytryptamine receptor 2C structureClick to view 3D structure5-hydroxytryptamine receptor 2CP28335HumansPredicted (SEA)
Prediction Confidence Score
0.059
Applicability Domain
0.077 Low confidence
Statistical Significance
1.0
Supporting Reference Compounds
823
E-value
7784.69
Acetylcholinesterase structureClick to view 3D structureAcetylcholinesteraseP22303HumansPredicted (SEA)
Prediction Confidence Score
0.056
Applicability Domain
0.063 Low confidence
Statistical Significance
1.0
Supporting Reference Compounds
406
E-value
7784.69
Carbonic anhydrase 7 structureClick to view 3D structureCarbonic anhydrase 7P43166HumansPredicted (SEA)
Prediction Confidence Score
0.056
Applicability Domain
0.069 Low confidence
Statistical Significance
1.0
Supporting Reference Compounds
242
E-value
7784.61
Carbonic anhydrase 1 structureClick to view 3D structureCarbonic anhydrase 1P00915HumansPredicted (SEA)
Prediction Confidence Score
0.056
Applicability Domain
0.069 Low confidence
Statistical Significance
1.0
Supporting Reference Compounds
407
E-value
7784.92
5-hydroxytryptamine receptor 7 structureClick to view 3D structure5-hydroxytryptamine receptor 7P34969HumansPredicted (SEA)
Prediction Confidence Score
0.055
Applicability Domain
0.077 Low confidence
Statistical Significance
1.0
Supporting Reference Compounds
565
E-value
7784.61
D(3) dopamine receptor structureClick to view 3D structureD(3) dopamine receptorP35462HumansPredicted (SEA)
Prediction Confidence Score
0.055
Applicability Domain
0.077 Low confidence
Statistical Significance
1.0
Supporting Reference Compounds
861
E-value
7784.69
Alpha-2B adrenergic receptor structureClick to view 3D structureAlpha-2B adrenergic receptorP18089HumansPredicted (SEA)
Prediction Confidence Score
0.055
Applicability Domain
0.059 Low confidence
Statistical Significance
1.0
Supporting Reference Compounds
340
E-value
7784.69
D(4) dopamine receptor structureClick to view 3D structureD(4) dopamine receptorP21917HumansPredicted (SEA)
Prediction Confidence Score
0.055
Applicability Domain
0.077 Low confidence
Statistical Significance
1.0
Supporting Reference Compounds
524
E-value
7784.61
Tyrosyl-DNA phosphodiesterase 2 structureClick to view 3D structureTyrosyl-DNA phosphodiesterase 2O95551HumansPredicted (SEA)
Prediction Confidence Score
0.055
Applicability Domain
0.065 Low confidence
Statistical Significance
0.9998
Supporting Reference Compounds
60
E-value
7783.44
Alpha-2A adrenergic receptor structureClick to view 3D structureAlpha-2A adrenergic receptorP08913HumansPredicted (SEA)
Prediction Confidence Score
0.055
Applicability Domain
0.059 Low confidence
Statistical Significance
1.0
Supporting Reference Compounds
487
E-value
7784.69
Cytochrome P450 2C19 structureClick to view 3D structureCytochrome P450 2C19P33261HumansPredicted (SEA)
Prediction Confidence Score
0.054
Applicability Domain
0.061 Low confidence
Statistical Significance
1.0
Supporting Reference Compounds
825
E-value
7784.69
D(1A) dopamine receptor structureClick to view 3D structureD(1A) dopamine receptorP21728HumansPredicted (SEA)
Prediction Confidence Score
0.054
Applicability Domain
0.077 Low confidence
Statistical Significance
1.0
Supporting Reference Compounds
425
E-value
7784.69
Voltage-gated inwardly rectifying potassium channel KCNH2 structureClick to view 3D structureVoltage-gated inwardly rectifying potassium channel KCNH2Q12809HumansPredicted (SEA)
Prediction Confidence Score
0.054
Applicability Domain
0.058 Low confidence
Statistical Significance
1.0
Supporting Reference Compounds
1498
E-value
7784.69
Alpha-2C adrenergic receptor structureClick to view 3D structureAlpha-2C adrenergic receptorP18825HumansPredicted (SEA)
Prediction Confidence Score
0.054
Applicability Domain
0.059 Low confidence
Statistical Significance
1.0
Supporting Reference Compounds
386
E-value
7784.69
Click to view 3D structureSigma intracellular receptor 2Q5BJF2HumansPredicted (SEA)
Prediction Confidence Score
0.053
Applicability Domain
0.068 Low confidence
Statistical Significance
1.0
Supporting Reference Compounds
308
E-value
7784.69
Click to view 3D structureAlpha-1B adrenergic receptorP35368HumansPredicted (SEA)
Prediction Confidence Score
0.053
Applicability Domain
0.059 Low confidence
Statistical Significance
1.0
Supporting Reference Compounds
298
E-value
7784.69
Click to view 3D structureSodium-dependent serotonin transporterP31652Rattus norvegicusPredicted (SEA)
Prediction Confidence Score
0.053
Applicability Domain
0.056 Low confidence
Statistical Significance
1.0
Supporting Reference Compounds
297
E-value
7784.61
Estrogen receptor structureClick to view 3D structureEstrogen receptorP03372HumansKnownCauses endocrine disruption in humans by binding to and inhibiting the estrogen receptor. (A590)
Estrogen receptor beta structureClick to view 3D structureEstrogen receptor betaQ92731HumansKnownCauses endocrine disruption in humans by binding to and inhibiting the estrogen receptor. (A590)
Calcium-transporting ATPase type 2C member 1 structureClick to view 3D structureCalcium-transporting ATPase type 2C member 1P98194HumansKnownThis organochloride inhibits Na+/K+ ATPase and Ca2+ and Mg2+ ATPase, which are essential for the transport of calcium across membranes. This results in the accumulation of intracellular free calcium ions, which promotes release of neurotransmitters from storage vesicles, the subsequent depolarization of adjacent neurons, and the propagation of stimuli throughout the central nervous system. (T10)
Gamma-aminobutyric acid receptor subunit alpha-1 structureClick to view 3D structureGamma-aminobutyric acid receptor subunit alpha-1P14867HumansKnownThis organochloride antagonizes the action of the neurotransmitter gamma-aminobutyric acid (GABA) acting at the GABA-A receptors, effectively blocking the GABA-induced uptake of chloride ions and causing hyperexcitability of the central nervous system. (T10)
Gamma-aminobutyric acid receptor subunit alpha-2 structureClick to view 3D structureGamma-aminobutyric acid receptor subunit alpha-2P47869HumansKnownThis organochloride antagonizes the action of the neurotransmitter gamma-aminobutyric acid (GABA) acting at the GABA-A receptors, effectively blocking the GABA-induced uptake of chloride ions and causing hyperexcitability of the central nervous system. (T10)
Gamma-aminobutyric acid receptor subunit alpha-3 structureClick to view 3D structureGamma-aminobutyric acid receptor subunit alpha-3P34903HumansKnownThis organochloride antagonizes the action of the neurotransmitter gamma-aminobutyric acid (GABA) acting at the GABA-A receptors, effectively blocking the GABA-induced uptake of chloride ions and causing hyperexcitability of the central nervous system. (T10)
Gamma-aminobutyric acid receptor subunit alpha-4 structureClick to view 3D structureGamma-aminobutyric acid receptor subunit alpha-4P48169HumansKnownThis organochloride antagonizes the action of the neurotransmitter gamma-aminobutyric acid (GABA) acting at the GABA-A receptors, effectively blocking the GABA-induced uptake of chloride ions and causing hyperexcitability of the central nervous system. (T10)
Gamma-aminobutyric acid receptor subunit alpha-5 structureClick to view 3D structureGamma-aminobutyric acid receptor subunit alpha-5P31644HumansKnownThis organochloride antagonizes the action of the neurotransmitter gamma-aminobutyric acid (GABA) acting at the GABA-A receptors, effectively blocking the GABA-induced uptake of chloride ions and causing hyperexcitability of the central nervous system. (T10)
Click to view 3D structureGamma-aminobutyric acid receptor subunit alpha-6Q16445HumansKnownThis organochloride antagonizes the action of the neurotransmitter gamma-aminobutyric acid (GABA) acting at the GABA-A receptors, effectively blocking the GABA-induced uptake of chloride ions and causing hyperexcitability of the central nervous system. (T10)
Gamma-aminobutyric acid receptor subunit beta-1 structureClick to view 3D structureGamma-aminobutyric acid receptor subunit beta-1P18505HumansKnownThis organochloride antagonizes the action of the neurotransmitter gamma-aminobutyric acid (GABA) acting at the GABA-A receptors, effectively blocking the GABA-induced uptake of chloride ions and causing hyperexcitability of the central nervous system. (T10)
Gamma-aminobutyric acid receptor subunit beta-2 structureClick to view 3D structureGamma-aminobutyric acid receptor subunit beta-2P47870HumansKnownThis organochloride antagonizes the action of the neurotransmitter gamma-aminobutyric acid (GABA) acting at the GABA-A receptors, effectively blocking the GABA-induced uptake of chloride ions and causing hyperexcitability of the central nervous system. (T10)
Gamma-aminobutyric acid receptor subunit beta-3 structureClick to view 3D structureGamma-aminobutyric acid receptor subunit beta-3P28472HumansKnownThis organochloride antagonizes the action of the neurotransmitter gamma-aminobutyric acid (GABA) acting at the GABA-A receptors, effectively blocking the GABA-induced uptake of chloride ions and causing hyperexcitability of the central nervous system. (T10)
Gamma-aminobutyric acid receptor subunit delta structureClick to view 3D structureGamma-aminobutyric acid receptor subunit deltaO14764HumansKnownThis organochloride antagonizes the action of the neurotransmitter gamma-aminobutyric acid (GABA) acting at the GABA-A receptors, effectively blocking the GABA-induced uptake of chloride ions and causing hyperexcitability of the central nervous system. (T10)
Click to view 3D structureGamma-aminobutyric acid receptor subunit epsilonP78334HumansKnownThis organochloride antagonizes the action of the neurotransmitter gamma-aminobutyric acid (GABA) acting at the GABA-A receptors, effectively blocking the GABA-induced uptake of chloride ions and causing hyperexcitability of the central nervous system. (T10)
Click to view 3D structureGamma-aminobutyric acid receptor subunit gamma-1Q8N1C3HumansKnownThis organochloride antagonizes the action of the neurotransmitter gamma-aminobutyric acid (GABA) acting at the GABA-A receptors, effectively blocking the GABA-induced uptake of chloride ions and causing hyperexcitability of the central nervous system. (T10)
Gamma-aminobutyric acid receptor subunit gamma-2 structureClick to view 3D structureGamma-aminobutyric acid receptor subunit gamma-2P18507HumansKnownThis organochloride antagonizes the action of the neurotransmitter gamma-aminobutyric acid (GABA) acting at the GABA-A receptors, effectively blocking the GABA-induced uptake of chloride ions and causing hyperexcitability of the central nervous system. (T10)
Click to view 3D structureGamma-aminobutyric acid receptor subunit gamma-3Q99928HumansKnownThis organochloride antagonizes the action of the neurotransmitter gamma-aminobutyric acid (GABA) acting at the GABA-A receptors, effectively blocking the GABA-induced uptake of chloride ions and causing hyperexcitability of the central nervous system. (T10)
Gamma-aminobutyric acid receptor subunit pi structureClick to view 3D structureGamma-aminobutyric acid receptor subunit piO00591HumansKnownThis organochloride antagonizes the action of the neurotransmitter gamma-aminobutyric acid (GABA) acting at the GABA-A receptors, effectively blocking the GABA-induced uptake of chloride ions and causing hyperexcitability of the central nervous system. (T10)
Gamma-aminobutyric acid receptor subunit rho-1 structureClick to view 3D structureGamma-aminobutyric acid receptor subunit rho-1P24046HumansKnownThis organochloride antagonizes the action of the neurotransmitter gamma-aminobutyric acid (GABA) acting at the GABA-A receptors, effectively blocking the GABA-induced uptake of chloride ions and causing hyperexcitability of the central nervous system. (T10)
Click to view 3D structureGamma-aminobutyric acid receptor subunit rho-2P28476HumansKnownThis organochloride antagonizes the action of the neurotransmitter gamma-aminobutyric acid (GABA) acting at the GABA-A receptors, effectively blocking the GABA-induced uptake of chloride ions and causing hyperexcitability of the central nervous system. (T10)
Click to view 3D structureGamma-aminobutyric acid receptor subunit rho-3A8MPY1HumansKnownThis organochloride antagonizes the action of the neurotransmitter gamma-aminobutyric acid (GABA) acting at the GABA-A receptors, effectively blocking the GABA-induced uptake of chloride ions and causing hyperexcitability of the central nervous system. (T10)
Click to view 3D structureGamma-aminobutyric acid receptor subunit thetaQ9UN88HumansKnownThis organochloride antagonizes the action of the neurotransmitter gamma-aminobutyric acid (GABA) acting at the GABA-A receptors, effectively blocking the GABA-induced uptake of chloride ions and causing hyperexcitability of the central nervous system. (T10)
Click to view 3D structureSarcoplasmic/endoplasmic reticulum calcium ATPase 1O14983HumansKnownThis organochloride inhibits Na+/K+ ATPase and Ca2+ and Mg2+ ATPase, which are essential for the transport of calcium across membranes. This results in the accumulation of intracellular free calcium ions, which promotes release of neurotransmitters from storage vesicles, the subsequent depolarization of adjacent neurons, and the propagation of stimuli throughout the central nervous system. (T10)
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 structureClick to view 3D structureSarcoplasmic/endoplasmic reticulum calcium ATPase 2P16615HumansKnownThis organochloride inhibits Na+/K+ ATPase and Ca2+ and Mg2+ ATPase, which are essential for the transport of calcium across membranes. This results in the accumulation of intracellular free calcium ions, which promotes release of neurotransmitters from storage vesicles, the subsequent depolarization of adjacent neurons, and the propagation of stimuli throughout the central nervous system. (T10)
Sodium/potassium-transporting ATPase subunit alpha-1 structureClick to view 3D structureSodium/potassium-transporting ATPase subunit alpha-1P05023HumansKnownThis organochloride inhibits Na+/K+ ATPase and Ca2+ and Mg2+ ATPase, which are essential for the transport of calcium across membranes. This results in the accumulation of intracellular free calcium ions, which promotes release of neurotransmitters from storage vesicles, the subsequent depolarization of adjacent neurons, and the propagation of stimuli throughout the central nervous system. (T10)
Click to view 3D structureSodium/potassium-transporting ATPase subunit alpha-2P50993HumansKnownThis organochloride inhibits Na+/K+ ATPase and Ca2+ and Mg2+ ATPase, which are essential for the transport of calcium across membranes. This results in the accumulation of intracellular free calcium ions, which promotes release of neurotransmitters from storage vesicles, the subsequent depolarization of adjacent neurons, and the propagation of stimuli throughout the central nervous system. (T10)
Sodium/potassium-transporting ATPase subunit alpha-3 structureClick to view 3D structureSodium/potassium-transporting ATPase subunit alpha-3P13637HumansKnownThis organochloride inhibits Na+/K+ ATPase and Ca2+ and Mg2+ ATPase, which are essential for the transport of calcium across membranes. This results in the accumulation of intracellular free calcium ions, which promotes release of neurotransmitters from storage vesicles, the subsequent depolarization of adjacent neurons, and the propagation of stimuli throughout the central nervous system. (T10)
Sodium/potassium-transporting ATPase subunit alpha-4 structureClick to view 3D structureSodium/potassium-transporting ATPase subunit alpha-4Q13733HumansKnownThis organochloride inhibits Na+/K+ ATPase and Ca2+ and Mg2+ ATPase, which are essential for the transport of calcium across membranes. This results in the accumulation of intracellular free calcium ions, which promotes release of neurotransmitters from storage vesicles, the subsequent depolarization of adjacent neurons, and the propagation of stimuli throughout the central nervous system. (T10)
Sodium/potassium-transporting ATPase subunit beta-1 structureClick to view 3D structureSodium/potassium-transporting ATPase subunit beta-1P05026HumansKnownThis organochloride inhibits Na+/K+ ATPase and Ca2+ and Mg2+ ATPase, which are essential for the transport of calcium across membranes. This results in the accumulation of intracellular free calcium ions, which promotes release of neurotransmitters from storage vesicles, the subsequent depolarization of adjacent neurons, and the propagation of stimuli throughout the central nervous system. (T10)
Click to view 3D structureSodium/potassium-transporting ATPase subunit beta-2P14415HumansKnownThis organochloride inhibits Na+/K+ ATPase and Ca2+ and Mg2+ ATPase, which are essential for the transport of calcium across membranes. This results in the accumulation of intracellular free calcium ions, which promotes release of neurotransmitters from storage vesicles, the subsequent depolarization of adjacent neurons, and the propagation of stimuli throughout the central nervous system. (T10)
Click to view 3D structureSodium/potassium-transporting ATPase subunit beta-3P54709HumansKnownThis organochloride inhibits Na+/K+ ATPase and Ca2+ and Mg2+ ATPase, which are essential for the transport of calcium across membranes. This results in the accumulation of intracellular free calcium ions, which promotes release of neurotransmitters from storage vesicles, the subsequent depolarization of adjacent neurons, and the propagation of stimuli throughout the central nervous system. (T10)
Sodium/potassium-transporting ATPase subunit gamma structureClick to view 3D structureSodium/potassium-transporting ATPase subunit gammaP54710HumansKnownThis organochloride inhibits Na+/K+ ATPase and Ca2+ and Mg2+ ATPase, which are essential for the transport of calcium across membranes. This results in the accumulation of intracellular free calcium ions, which promotes release of neurotransmitters from storage vesicles, the subsequent depolarization of adjacent neurons, and the propagation of stimuli throughout the central nervous system. (T10)
Concentrations
Not Available
External Links
DrugBank IDNot Available
HMDB IDHMDB0059573
FooDB IDNot Available
Phenol Explorer IDNot Available
KNApSAcK IDNot Available
BiGG IDNot Available
BioCyc IDNot Available
METLIN IDNot Available
PDB IDNot Available
Wikipedia LinkMirex
Chemspider ID16054
ChEBI ID34852
PubChem Compound ID16945
Kegg Compound IDC14184
YMDB IDNot Available
ECMDB IDNot Available
References
Synthesis ReferenceNot Available
MSDSNot Available
General References
  1. Mehendale HM, Ho IK, Desaiah D: Possible molecular mechanism of mirex-induced hepatobiliary dysfunction. Drug Metab Dispos. 1979 Jan-Feb;7(1):28-33. [PubMed: 35323]
  2. ATSDR - Agency for Toxic Substances and Disease Registry (2001). Minimal Risk Levels (MRLs) for Hazardous Substances. U.S. Public Health Service in collaboration with U.S. Environmental Protection Agency (EPA). - http://www.atsdr.cdc.gov/mrls/
  3. International Agency for Research on Cancer (2014). IARC Monographs on the Evaluation of Carcinogenic Risks to Humans. - http://monographs.iarc.fr/index.php
  4. ATSDR - Agency for Toxic Substances and Disease Registry (1996). Toxicological profile for mirex and chlordecone. U.S. Public Health Service in collaboration with U.S. Environmental Protection Agency (EPA). - http://www.atsdr.cdc.gov/tfacts66.html
  5. Wikipedia. Mirex. Last Updated 24 May 2009. - http://en.wikipedia.org/wiki/Mirex
  6. Meister RT and Sine C (2006). Crop Protection Handbook. Volume 92. Willoughby, OH: Meister Publishing Company.
  7. WHO (1984). Environmental Health Criteria: Mirex.