Click to view 3D structure | histidine kinase | O32393 | Arthrospira platensis | Predicted (SEA) | - Prediction Confidence Score
- 0.095
- Applicability Domain
- 0.095 Low confidence
- Statistical Significance
- 0.3238
- Supporting Reference Compounds
- 1
- E-value
- 2520.68
|
Click to view 3D structure | GABA receptor subunit | Q75NA5 | Musca domestica | Predicted (SEA) | - Prediction Confidence Score
- 0.091
- Applicability Domain
- 0.138 Low confidence
- Statistical Significance
- 0.2306
- Supporting Reference Compounds
- 2
- E-value
- 1794.97
|
Click to view 3D structure | D(2) dopamine receptor | P14416 | Humans | Predicted (SEA) | - Prediction Confidence Score
- 0.068
- Applicability Domain
- 0.095 Low confidence
- Statistical Significance
- 1.0
- Supporting Reference Compounds
- 1103
- E-value
- 7784.61
|
Click to view 3D structure | Sigma non-opioid intracellular receptor 1 | Q99720 | Humans | Predicted (SEA) | - Prediction Confidence Score
- 0.066
- Applicability Domain
- 0.095 Low confidence
- Statistical Significance
- 1.0
- Supporting Reference Compounds
- 562
- E-value
- 7784.69
|
Click to view 3D structure | 5-hydroxytryptamine receptor 1A | P08908 | Humans | Predicted (SEA) | - Prediction Confidence Score
- 0.061
- Applicability Domain
- 0.077 Low confidence
- Statistical Significance
- 1.0
- Supporting Reference Compounds
- 953
- E-value
- 7784.61
|
Click to view 3D structure | 5-hydroxytryptamine receptor 2A | P28223 | Humans | Predicted (SEA) | - Prediction Confidence Score
- 0.06
- Applicability Domain
- 0.077 Low confidence
- Statistical Significance
- 1.0
- Supporting Reference Compounds
- 955
- E-value
- 7784.61
|
Click to view 3D structure | Phenylalanine--tRNA ligase alpha subunit | Q8P1K1 | Streptococcus pyogenes serotype M18 (strain MGAS8232) | Predicted (SEA) | - Prediction Confidence Score
- 0.06
- Applicability Domain
- 0.06 Low confidence
- Statistical Significance
- 0.9176
- Supporting Reference Compounds
- 1
- E-value
- 7143.13
|
Click to view 3D structure | Gamma-aminobutyric acid receptor subunit beta-3 | P28472 | Humans | Predicted (SEA) | - Prediction Confidence Score
- 0.06
- Applicability Domain
- 0.138 Low confidence
- Statistical Significance
- 0.9322
- Supporting Reference Compounds
- 3
- E-value
- 7257.03
|
Click to view 3D structure | 5-hydroxytryptamine receptor 2C | P28335 | Humans | Predicted (SEA) | - Prediction Confidence Score
- 0.059
- Applicability Domain
- 0.077 Low confidence
- Statistical Significance
- 1.0
- Supporting Reference Compounds
- 823
- E-value
- 7784.69
|
Click to view 3D structure | Acetylcholinesterase | P22303 | Humans | Predicted (SEA) | - Prediction Confidence Score
- 0.056
- Applicability Domain
- 0.063 Low confidence
- Statistical Significance
- 1.0
- Supporting Reference Compounds
- 406
- E-value
- 7784.69
|
Click to view 3D structure | Carbonic anhydrase 7 | P43166 | Humans | Predicted (SEA) | - Prediction Confidence Score
- 0.056
- Applicability Domain
- 0.069 Low confidence
- Statistical Significance
- 1.0
- Supporting Reference Compounds
- 242
- E-value
- 7784.61
|
Click to view 3D structure | Carbonic anhydrase 1 | P00915 | Humans | Predicted (SEA) | - Prediction Confidence Score
- 0.056
- Applicability Domain
- 0.069 Low confidence
- Statistical Significance
- 1.0
- Supporting Reference Compounds
- 407
- E-value
- 7784.92
|
Click to view 3D structure | 5-hydroxytryptamine receptor 7 | P34969 | Humans | Predicted (SEA) | - Prediction Confidence Score
- 0.055
- Applicability Domain
- 0.077 Low confidence
- Statistical Significance
- 1.0
- Supporting Reference Compounds
- 565
- E-value
- 7784.61
|
Click to view 3D structure | D(3) dopamine receptor | P35462 | Humans | Predicted (SEA) | - Prediction Confidence Score
- 0.055
- Applicability Domain
- 0.077 Low confidence
- Statistical Significance
- 1.0
- Supporting Reference Compounds
- 861
- E-value
- 7784.69
|
Click to view 3D structure | Alpha-2B adrenergic receptor | P18089 | Humans | Predicted (SEA) | - Prediction Confidence Score
- 0.055
- Applicability Domain
- 0.059 Low confidence
- Statistical Significance
- 1.0
- Supporting Reference Compounds
- 340
- E-value
- 7784.69
|
Click to view 3D structure | D(4) dopamine receptor | P21917 | Humans | Predicted (SEA) | - Prediction Confidence Score
- 0.055
- Applicability Domain
- 0.077 Low confidence
- Statistical Significance
- 1.0
- Supporting Reference Compounds
- 524
- E-value
- 7784.61
|
Click to view 3D structure | Tyrosyl-DNA phosphodiesterase 2 | O95551 | Humans | Predicted (SEA) | - Prediction Confidence Score
- 0.055
- Applicability Domain
- 0.065 Low confidence
- Statistical Significance
- 0.9998
- Supporting Reference Compounds
- 60
- E-value
- 7783.44
|
Click to view 3D structure | Alpha-2A adrenergic receptor | P08913 | Humans | Predicted (SEA) | - Prediction Confidence Score
- 0.055
- Applicability Domain
- 0.059 Low confidence
- Statistical Significance
- 1.0
- Supporting Reference Compounds
- 487
- E-value
- 7784.69
|
Click to view 3D structure | Cytochrome P450 2C19 | P33261 | Humans | Predicted (SEA) | - Prediction Confidence Score
- 0.054
- Applicability Domain
- 0.061 Low confidence
- Statistical Significance
- 1.0
- Supporting Reference Compounds
- 825
- E-value
- 7784.69
|
Click to view 3D structure | D(1A) dopamine receptor | P21728 | Humans | Predicted (SEA) | - Prediction Confidence Score
- 0.054
- Applicability Domain
- 0.077 Low confidence
- Statistical Significance
- 1.0
- Supporting Reference Compounds
- 425
- E-value
- 7784.69
|
Click to view 3D structure | Voltage-gated inwardly rectifying potassium channel KCNH2 | Q12809 | Humans | Predicted (SEA) | - Prediction Confidence Score
- 0.054
- Applicability Domain
- 0.058 Low confidence
- Statistical Significance
- 1.0
- Supporting Reference Compounds
- 1498
- E-value
- 7784.69
|
Click to view 3D structure | Alpha-2C adrenergic receptor | P18825 | Humans | Predicted (SEA) | - Prediction Confidence Score
- 0.054
- Applicability Domain
- 0.059 Low confidence
- Statistical Significance
- 1.0
- Supporting Reference Compounds
- 386
- E-value
- 7784.69
|
Click to view 3D structure | Sigma intracellular receptor 2 | Q5BJF2 | Humans | Predicted (SEA) | - Prediction Confidence Score
- 0.053
- Applicability Domain
- 0.068 Low confidence
- Statistical Significance
- 1.0
- Supporting Reference Compounds
- 308
- E-value
- 7784.69
|
Click to view 3D structure | Alpha-1B adrenergic receptor | P35368 | Humans | Predicted (SEA) | - Prediction Confidence Score
- 0.053
- Applicability Domain
- 0.059 Low confidence
- Statistical Significance
- 1.0
- Supporting Reference Compounds
- 298
- E-value
- 7784.69
|
Click to view 3D structure | Sodium-dependent serotonin transporter | P31652 | Rattus norvegicus | Predicted (SEA) | - Prediction Confidence Score
- 0.053
- Applicability Domain
- 0.056 Low confidence
- Statistical Significance
- 1.0
- Supporting Reference Compounds
- 297
- E-value
- 7784.61
|
Click to view 3D structure | Estrogen receptor | P03372 | Humans | Known | Causes endocrine disruption in humans by binding to and inhibiting the estrogen receptor. (A590) |
Click to view 3D structure | Estrogen receptor beta | Q92731 | Humans | Known | Causes endocrine disruption in humans by binding to and inhibiting the estrogen receptor. (A590) |
Click to view 3D structure | Calcium-transporting ATPase type 2C member 1 | P98194 | Humans | Known | This organochloride inhibits Na+/K+ ATPase and Ca2+ and Mg2+ ATPase, which are essential for the transport of calcium across membranes. This results in the accumulation of intracellular free calcium ions, which promotes release of neurotransmitters from storage vesicles, the subsequent depolarization of adjacent neurons, and the propagation of stimuli throughout the central nervous system. (T10) |
Click to view 3D structure | Gamma-aminobutyric acid receptor subunit alpha-1 | P14867 | Humans | Known | This organochloride antagonizes the action of the neurotransmitter gamma-aminobutyric acid (GABA) acting at the GABA-A receptors, effectively blocking the GABA-induced uptake of chloride ions and causing hyperexcitability of the central nervous system. (T10) |
Click to view 3D structure | Gamma-aminobutyric acid receptor subunit alpha-2 | P47869 | Humans | Known | This organochloride antagonizes the action of the neurotransmitter gamma-aminobutyric acid (GABA) acting at the GABA-A receptors, effectively blocking the GABA-induced uptake of chloride ions and causing hyperexcitability of the central nervous system. (T10) |
Click to view 3D structure | Gamma-aminobutyric acid receptor subunit alpha-3 | P34903 | Humans | Known | This organochloride antagonizes the action of the neurotransmitter gamma-aminobutyric acid (GABA) acting at the GABA-A receptors, effectively blocking the GABA-induced uptake of chloride ions and causing hyperexcitability of the central nervous system. (T10) |
Click to view 3D structure | Gamma-aminobutyric acid receptor subunit alpha-4 | P48169 | Humans | Known | This organochloride antagonizes the action of the neurotransmitter gamma-aminobutyric acid (GABA) acting at the GABA-A receptors, effectively blocking the GABA-induced uptake of chloride ions and causing hyperexcitability of the central nervous system. (T10) |
Click to view 3D structure | Gamma-aminobutyric acid receptor subunit alpha-5 | P31644 | Humans | Known | This organochloride antagonizes the action of the neurotransmitter gamma-aminobutyric acid (GABA) acting at the GABA-A receptors, effectively blocking the GABA-induced uptake of chloride ions and causing hyperexcitability of the central nervous system. (T10) |
Click to view 3D structure | Gamma-aminobutyric acid receptor subunit alpha-6 | Q16445 | Humans | Known | This organochloride antagonizes the action of the neurotransmitter gamma-aminobutyric acid (GABA) acting at the GABA-A receptors, effectively blocking the GABA-induced uptake of chloride ions and causing hyperexcitability of the central nervous system. (T10) |
Click to view 3D structure | Gamma-aminobutyric acid receptor subunit beta-1 | P18505 | Humans | Known | This organochloride antagonizes the action of the neurotransmitter gamma-aminobutyric acid (GABA) acting at the GABA-A receptors, effectively blocking the GABA-induced uptake of chloride ions and causing hyperexcitability of the central nervous system. (T10) |
Click to view 3D structure | Gamma-aminobutyric acid receptor subunit beta-2 | P47870 | Humans | Known | This organochloride antagonizes the action of the neurotransmitter gamma-aminobutyric acid (GABA) acting at the GABA-A receptors, effectively blocking the GABA-induced uptake of chloride ions and causing hyperexcitability of the central nervous system. (T10) |
Click to view 3D structure | Gamma-aminobutyric acid receptor subunit beta-3 | P28472 | Humans | Known | This organochloride antagonizes the action of the neurotransmitter gamma-aminobutyric acid (GABA) acting at the GABA-A receptors, effectively blocking the GABA-induced uptake of chloride ions and causing hyperexcitability of the central nervous system. (T10) |
Click to view 3D structure | Gamma-aminobutyric acid receptor subunit delta | O14764 | Humans | Known | This organochloride antagonizes the action of the neurotransmitter gamma-aminobutyric acid (GABA) acting at the GABA-A receptors, effectively blocking the GABA-induced uptake of chloride ions and causing hyperexcitability of the central nervous system. (T10) |
Click to view 3D structure | Gamma-aminobutyric acid receptor subunit epsilon | P78334 | Humans | Known | This organochloride antagonizes the action of the neurotransmitter gamma-aminobutyric acid (GABA) acting at the GABA-A receptors, effectively blocking the GABA-induced uptake of chloride ions and causing hyperexcitability of the central nervous system. (T10) |
Click to view 3D structure | Gamma-aminobutyric acid receptor subunit gamma-1 | Q8N1C3 | Humans | Known | This organochloride antagonizes the action of the neurotransmitter gamma-aminobutyric acid (GABA) acting at the GABA-A receptors, effectively blocking the GABA-induced uptake of chloride ions and causing hyperexcitability of the central nervous system. (T10) |
Click to view 3D structure | Gamma-aminobutyric acid receptor subunit gamma-2 | P18507 | Humans | Known | This organochloride antagonizes the action of the neurotransmitter gamma-aminobutyric acid (GABA) acting at the GABA-A receptors, effectively blocking the GABA-induced uptake of chloride ions and causing hyperexcitability of the central nervous system. (T10) |
Click to view 3D structure | Gamma-aminobutyric acid receptor subunit gamma-3 | Q99928 | Humans | Known | This organochloride antagonizes the action of the neurotransmitter gamma-aminobutyric acid (GABA) acting at the GABA-A receptors, effectively blocking the GABA-induced uptake of chloride ions and causing hyperexcitability of the central nervous system. (T10) |
Click to view 3D structure | Gamma-aminobutyric acid receptor subunit pi | O00591 | Humans | Known | This organochloride antagonizes the action of the neurotransmitter gamma-aminobutyric acid (GABA) acting at the GABA-A receptors, effectively blocking the GABA-induced uptake of chloride ions and causing hyperexcitability of the central nervous system. (T10) |
Click to view 3D structure | Gamma-aminobutyric acid receptor subunit rho-1 | P24046 | Humans | Known | This organochloride antagonizes the action of the neurotransmitter gamma-aminobutyric acid (GABA) acting at the GABA-A receptors, effectively blocking the GABA-induced uptake of chloride ions and causing hyperexcitability of the central nervous system. (T10) |
Click to view 3D structure | Gamma-aminobutyric acid receptor subunit rho-2 | P28476 | Humans | Known | This organochloride antagonizes the action of the neurotransmitter gamma-aminobutyric acid (GABA) acting at the GABA-A receptors, effectively blocking the GABA-induced uptake of chloride ions and causing hyperexcitability of the central nervous system. (T10) |
Click to view 3D structure | Gamma-aminobutyric acid receptor subunit rho-3 | A8MPY1 | Humans | Known | This organochloride antagonizes the action of the neurotransmitter gamma-aminobutyric acid (GABA) acting at the GABA-A receptors, effectively blocking the GABA-induced uptake of chloride ions and causing hyperexcitability of the central nervous system. (T10) |
Click to view 3D structure | Gamma-aminobutyric acid receptor subunit theta | Q9UN88 | Humans | Known | This organochloride antagonizes the action of the neurotransmitter gamma-aminobutyric acid (GABA) acting at the GABA-A receptors, effectively blocking the GABA-induced uptake of chloride ions and causing hyperexcitability of the central nervous system. (T10) |
Click to view 3D structure | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | O14983 | Humans | Known | This organochloride inhibits Na+/K+ ATPase and Ca2+ and Mg2+ ATPase, which are essential for the transport of calcium across membranes. This results in the accumulation of intracellular free calcium ions, which promotes release of neurotransmitters from storage vesicles, the subsequent depolarization of adjacent neurons, and the propagation of stimuli throughout the central nervous system. (T10) |
Click to view 3D structure | Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 | P16615 | Humans | Known | This organochloride inhibits Na+/K+ ATPase and Ca2+ and Mg2+ ATPase, which are essential for the transport of calcium across membranes. This results in the accumulation of intracellular free calcium ions, which promotes release of neurotransmitters from storage vesicles, the subsequent depolarization of adjacent neurons, and the propagation of stimuli throughout the central nervous system. (T10) |
Click to view 3D structure | Sodium/potassium-transporting ATPase subunit alpha-1 | P05023 | Humans | Known | This organochloride inhibits Na+/K+ ATPase and Ca2+ and Mg2+ ATPase, which are essential for the transport of calcium across membranes. This results in the accumulation of intracellular free calcium ions, which promotes release of neurotransmitters from storage vesicles, the subsequent depolarization of adjacent neurons, and the propagation of stimuli throughout the central nervous system. (T10) |
Click to view 3D structure | Sodium/potassium-transporting ATPase subunit alpha-2 | P50993 | Humans | Known | This organochloride inhibits Na+/K+ ATPase and Ca2+ and Mg2+ ATPase, which are essential for the transport of calcium across membranes. This results in the accumulation of intracellular free calcium ions, which promotes release of neurotransmitters from storage vesicles, the subsequent depolarization of adjacent neurons, and the propagation of stimuli throughout the central nervous system. (T10) |
Click to view 3D structure | Sodium/potassium-transporting ATPase subunit alpha-3 | P13637 | Humans | Known | This organochloride inhibits Na+/K+ ATPase and Ca2+ and Mg2+ ATPase, which are essential for the transport of calcium across membranes. This results in the accumulation of intracellular free calcium ions, which promotes release of neurotransmitters from storage vesicles, the subsequent depolarization of adjacent neurons, and the propagation of stimuli throughout the central nervous system. (T10) |
Click to view 3D structure | Sodium/potassium-transporting ATPase subunit alpha-4 | Q13733 | Humans | Known | This organochloride inhibits Na+/K+ ATPase and Ca2+ and Mg2+ ATPase, which are essential for the transport of calcium across membranes. This results in the accumulation of intracellular free calcium ions, which promotes release of neurotransmitters from storage vesicles, the subsequent depolarization of adjacent neurons, and the propagation of stimuli throughout the central nervous system. (T10) |
Click to view 3D structure | Sodium/potassium-transporting ATPase subunit beta-1 | P05026 | Humans | Known | This organochloride inhibits Na+/K+ ATPase and Ca2+ and Mg2+ ATPase, which are essential for the transport of calcium across membranes. This results in the accumulation of intracellular free calcium ions, which promotes release of neurotransmitters from storage vesicles, the subsequent depolarization of adjacent neurons, and the propagation of stimuli throughout the central nervous system. (T10) |
Click to view 3D structure | Sodium/potassium-transporting ATPase subunit beta-2 | P14415 | Humans | Known | This organochloride inhibits Na+/K+ ATPase and Ca2+ and Mg2+ ATPase, which are essential for the transport of calcium across membranes. This results in the accumulation of intracellular free calcium ions, which promotes release of neurotransmitters from storage vesicles, the subsequent depolarization of adjacent neurons, and the propagation of stimuli throughout the central nervous system. (T10) |
Click to view 3D structure | Sodium/potassium-transporting ATPase subunit beta-3 | P54709 | Humans | Known | This organochloride inhibits Na+/K+ ATPase and Ca2+ and Mg2+ ATPase, which are essential for the transport of calcium across membranes. This results in the accumulation of intracellular free calcium ions, which promotes release of neurotransmitters from storage vesicles, the subsequent depolarization of adjacent neurons, and the propagation of stimuli throughout the central nervous system. (T10) |
Click to view 3D structure | Sodium/potassium-transporting ATPase subunit gamma | P54710 | Humans | Known | This organochloride inhibits Na+/K+ ATPase and Ca2+ and Mg2+ ATPase, which are essential for the transport of calcium across membranes. This results in the accumulation of intracellular free calcium ions, which promotes release of neurotransmitters from storage vesicles, the subsequent depolarization of adjacent neurons, and the propagation of stimuli throughout the central nervous system. (T10) |