Antimony trichloride (CED0010540)

Record Information

Version

1.0

Creation Date

2009-06-16 18:48:55 UTC

Update Date

2026-08-17 20:48:02 UTC

SynCED ID

CED0010540

Secondary Accession Numbers

CHEM000751
T3D0874

Identification

Common Name

Antimony trichloride

Class

Small Molecule

Description

Antimony trichloride is an exogenous inorganic compound with the chemical formula Cl3Sb and an average molecular weight of 228.12 g/mol. It exists as a solid at room temperature. Antimony trichloride belongs to the metalloid chlorides, a subclass of metalloid salts within the inorganic compounds. In chemical and applied contexts, it serves as a Lewis acid and a colorimetric reagent, while biologically it acts as an apoptosis inducer. The compound is released from 18 recorded sources. These include electrical and electronic equipment such as amplifiers, antennas, auxiliary devices, coils, and communication cables or conductors, among eight others. It is also found in building and construction materials like roofs, tents, or canopies, as well as in household cleaning and consumer products including non-electric simulated smoking devices and other smoking requisites. Additionally, it is associated with food, food processing, and cookware, specifically within fermentation processes for beer. Antimony trichloride has 19 recorded protein targets, including glutathione S-transferase A1 (GSTA1), glutathione S-transferase A2 (GSTA2), glutathione S-transferase A3 (GSTA3), and glutathione S-transferase Mu 4 (GSTM4). Trivalent antimony inhibits glutathione-S-transferases from human erythrocytes, which reduces their detoxification ability.

Contaminant Type

Antimony Compound
Food Toxin
Inorganic Compound
Pollutant
Synthetic Compound

Chemical Structure

MOL SDF PDB SMILES InChI

Synonyms

Value	Source
Antimontrichlorid	ChEBI
Antimony chloride	ChEBI
Antimony(III) chloride	ChEBI
Antimony(III) trichloride	ChEBI
Chlorure antimonieux	ChEBI
SB2CL6	ChEBI
SBCL3	ChEBI
Trichlorostibine	ChEBI
Trichlorure d'antimoine	ChEBI

Chemical Formula

Cl₃Sb

Average Molecular Mass

228.120 g/mol

Monoisotopic Mass

225.810 g/mol

CAS Registry Number

10025-91-9

IUPAC Name

trichlorostibane

Traditional Name

antimony trichloride

SMILES

Cl[Sb](Cl)Cl

InChI Identifier

InChI=1S/3ClH.Sb/h3*1H;/q;;;+3/p-3

InChI Key

FAPDDOBMIUGHIN-UHFFFAOYSA-K

Chemical Taxonomy

Description

Belongs to the class of inorganic compounds known as metalloid chlorides. These are inorganic compounds in which the largest halogen atom is Chlorine, and the heaviest metal atom is a metalloid.

Kingdom

Inorganic compounds

Super Class

Mixed metal/non-metal compounds

Class

Metalloid salts

Sub Class

Metalloid chlorides

Direct Parent

Metalloid chlorides

Alternative Parents

Substituents

Metalloid chloride
Inorganic antimony salt
Inorganic chloride salt
Inorganic salt

Molecular Framework

Not Available

External Descriptors

inorganic chloride (CHEBI:74856 )
antimony molecular entity (CHEBI:74856 )

Biological Properties

Status

Detected and Not Quantified

Origin

Exogenous

Cellular Locations

Cytoplasm
Extracellular

Biofluid Locations

Not Available

Tissue Locations

Not Available

Applications

colorimetric reagent

Biological Roles

apoptosis inducer ?

Chemical Roles

Lewis acid ?

Organoleptic Effects

Not Available

Physical Properties

State

Solid

Appearance

White powder.

Experimental Properties

Property	Value
Melting Point	73°C
Boiling Point	Not Available
Solubility	Not Available

Predicted Properties

Property	Value	Source
logP	1.91	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	0	ChemAxon
Hydrogen Donor Count	0	ChemAxon
Polar Surface Area	0 Å²	ChemAxon
Rotatable Bond Count	0	ChemAxon
Refractivity	18.41 m³·mol⁻¹	ChemAxon
Polarizability	9.7 Å³	ChemAxon
Number of Rings	0	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	Yes	ChemAxon
MDDR-like Rule	No	ChemAxon

Spectra

Spectrum Type	Description	Splash Key	Deposition Date	View
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-001i-0090000000-415dd9b9b72c31bc9dfe	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-001i-0090000000-415dd9b9b72c31bc9dfe	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-001i-0090000000-415dd9b9b72c31bc9dfe	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-001i-0090000000-3f6f7d16f8f123b01f56	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-001i-0090000000-3f6f7d16f8f123b01f56	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-001i-0090000000-3f6f7d16f8f123b01f56	Not Available	View Spectrum

Toxicity Profile

Toxicity Values

Toxicity Value	Organism	Dose Descriptor	Route of Exposure	Predicted or Experimental	Toxicity Rating	Reference
525.0 mg/kg	Rat	LD50	Oral	experimental	Not Available	5
74.0 mg/kg	Guinea pig	LD50	Oral	experimental	Not Available	5

Toxicity / Toxin Class

Not Available

Mechanism of Toxicity

The inhalation data suggest that the myocardium is a target of antimony toxicity. It is possible that antimony affects circulating glucose by interfering with enzymes of the glycogenolysis and gluconeogenesis pathways. The mechanism of action of antimony remains unclear. However, some studies suggest that antimony combines with sulfhydryl groups including those in several enzymes important for tissue respiration. The antidotal action of BAL depends on its ability to prevent or break the union between antimony and vital enzymes. Moreover, the The cause of death is believed to be essentially the same as that in acute arsenic poisoning. (6, 3, 1)

Carcinogenicity (IARC Classification)

No indication of carcinogenicity (not listed by IARC). (2)

Minimum Risk Level

Not Available

Symptoms

Abdominal pain, vomiting, diarrhea can result from inhalation of antimony. Dyspnea, headache, vomiting,cough, conjunctivitis, and bloody purulent discharge from nose can result from inhalation exposure. Skin or eye contact can cause pain and redness of the exposed surface. (8, 3)

Treatment

Following oral exposure to antimony, administer charcoal as a slurry (240 mL water/30 g charcoal). Following inhalation exposure, move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with inhaled beta2 agonist and oral or parenteral corticosteroids. In case of eye exposure, irrigate exposed eyes with copious amounts of room temperature water for at least 15 minutes. Following dermal exposure, remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician may need to examine the area if irritation or pain persists. (7)

Health Effects

Health Effect	Relationship	Direction	Reference

Exposure Sources

Source ID	Source	Sector	Reference
CEDs000181	Ballast water?Ballast water, taken on by ships to maintain stability and balance, often contains a diverse array of microorganisms, including bacteria, viruses, and plankton.	Marine, shipping & aquaculture	Not Available
CEDs000182	Bilge water?Bilge water is a byproduct generated from the accumulation of water in the lowest part of a ship's hull, which may include a mixture of seawater, oil, fuel residues, and various contaminants.	Marine, shipping & aquaculture	Not Available
CEDs000499	Roofs?Roofs can be a significant source of synthetic chemical contamination due to the materials used in their construction and maintenance.	Building & Construction	Not Available
CEDs000503	Tents Or Canopies?Tents and canopies used in various applications can be a source of synthetic chemical contamination primarily due to the materials from which they are made.	Building & Construction	Not Available
CEDs000505	Amplifiers?Amplifiers, commonly used in various electronic devices to enhance signal strength, can be a source of synthetic chemical contamination due to the materials and processes involved in their production and disposal.	Electrical & Electronic Equipment	Not Available
CEDs000506	Antennas?Antennas, commonly used in communication technologies, can be a source of synthetic chemical contamination through the materials and coatings used in their construction.	Electrical & Electronic Equipment	Not Available
CEDs000507	Auxiliary Devices?Auxiliary devices, such as capacitors, transformers, and circuit breakers, are integral components in various electronic systems.	Electrical & Electronic Equipment	Not Available
CEDs000508	Coils?Coils are components used in various electrical and electronic applications, such as transformers, inductors, and motors.	Electrical & Electronic Equipment	Not Available
CEDs000510	Communication Cables Or Conductors?Communication cables or conductors are essential components in the transmission of data and signals in various applications, including telecommunications and networking.	Electrical & Electronic Equipment	Not Available
CEDs000511	Conductors Or Conductive Bodies Characterised By The Conductive Materials?Conductors, or conductive bodies, are materials that allow the flow of electrical current, typically made from metals such as copper, aluminum, or silver.	Electrical & Electronic Equipment	Not Available
CEDs000513	Cores Yokes Or Armatures?Cores, yokes, or armatures are components commonly found in electrical devices, used to facilitate the magnetic and electrical functions within motors, transformers, and generators.	Electrical & Electronic Equipment	Not Available
CEDs000514	Discharge Lamps?Discharge lamps, including fluorescent and high-intensity discharge (HID) lamps, are commonly used for lighting applications due to their energy efficiency and brightness.	Electrical & Electronic Equipment	Not Available
CEDs000517	Electric Switches?Electric switches, integral components in numerous devices, can be a source of synthetic chemical contamination due to the materials and manufacturing processes involved in their production.	Electrical & Electronic Equipment	Not Available
CEDs000518	Electrically Stimulated Smoking Devices?Electrically stimulated smoking devices, commonly known as e-cigarettes or vape pens, utilize electrical components to heat a liquid solution, often containing nicotine, flavorings, and other additives, to produce an aerosol for inhalation.	Electrical & Electronic Equipment	Not Available
CEDs000519	Electrodes?Electrodes, used in various electrical and electronic applications, can be a source of synthetic chemical contamination due to the materials from which they are constructed and the processes involved in their manufacturing.	Electrical & Electronic Equipment	Not Available
CEDs000520	Emergency Protective Devices?Emergency protective devices, such as circuit breakers and surge protectors, are essential components in electrical systems designed to prevent damage from overcurrent and surges.	Electrical & Electronic Equipment	Not Available
CEDs000521	Fixed Capacitors And Their Manufacture?Fixed capacitors are passive electronic components used to store and release electrical energy, playing a critical role in various circuits.	Electrical & Electronic Equipment	Not Available
CEDs000523	Gas Filled Discharge Tubes With Solid Cathode?Gas Filled Discharge Tubes with Solid Cathodes are electrical components that facilitate the flow of current by ionizing gas within a sealed tube.	Electrical & Electronic Equipment	Not Available
CEDs000524	Hybrid Capacitors?Hybrid capacitors are energy storage devices that combine the properties of electrolytic and supercapacitors, utilizing a combination of electrochemical principles to achieve higher energy density and power density.	Electrical & Electronic Equipment	Not Available
CEDs000529	Power Cables?Power cables are used to transmit electrical energy and are typically composed of conductive materials, insulation, and protective coatings.	Electrical & Electronic Equipment	Not Available
CEDs000544	Fermentation Processes For Beer?Fermentation processes for beer involve the conversion of sugars into alcohol and carbon dioxide by yeast.	Food, food processing & cookware	Not Available
CEDs000545	Food Preservation?Food preservation often involves the use of synthetic chemicals, such as preservatives, flavor enhancers, and color additives, to extend shelf life and enhance the sensory qualities of food products.	Food, food processing & cookware	Not Available
CEDs000559	Non Electric Simulated Smoking Devices?Non-electric simulated smoking devices, often designed to mimic the experience of smoking without combustion, can be sources of synthetic chemical contamination due to the materials and chemicals used in their construction and operation.	Household cleaning & consumer products	Not Available
CEDs000560	Other Smoking Requisites?Other smoking requisites, including items such as lighters, matches, and rolling papers, can introduce synthetic chemical contamination through various components and additives.	Household cleaning & consumer products	Not Available
CEDs000561	Perfumes Within Detergents And Soaps?Perfumes within detergents and soaps are synthetic fragrance compounds added to enhance the sensory experience of cleaning products.	Household cleaning & consumer products	Not Available
CEDs000563	Soap Detergents?Soap detergents are synthetic surfactants designed to enhance the cleaning efficacy of water by reducing surface tension, allowing for better interaction with dirt and grease.	Household cleaning & consumer products	Not Available
CEDs000579	Manufacture Of Iron Or Steel?The manufacture of iron or steel involves various processes, including smelting, refining, and alloying, which can result in the release of synthetic chemicals and contaminants.	Industrial manufacturing & chemical processing	Not Available
CEDs000581	Paper Making Machines?Paper making machines utilize various synthetic chemicals throughout the production process, including additives, coatings, and bleaching agents.	Industrial manufacturing & chemical processing	Not Available
CEDs000600	Herbicides And Algicides?Herbicides and algicides are synthetic chemicals primarily used to control unwanted plants and algae in various environments.	Agriculture & land management	Not Available
CEDs000603	Nematocides?Nematocides are synthetic chemicals specifically designed to control nematodes, which are microscopic roundworms that can cause significant damage to crops and plants.	Agriculture & land management	Not Available
CEDs000606	Plant Growth Regulators?Plant Growth Regulators (PGRs) are synthetic chemicals designed to influence the growth and development of plants.	Agriculture & land management	Not Available
CEDs000611	Anti Perspirants Or Body Deoderants?Antiperspirants and body deodorants commonly contain synthetic chemicals such as aluminum compounds, parabens, and synthetic fragrances.	Personal care & cosmetics	Not Available
CEDs000614	Essential Oils Or Perfumes?Essential oils and perfumes are complex mixtures of volatile compounds derived from natural or synthetic sources, commonly used for their aromatic properties.	Personal care & cosmetics	Not Available
CEDs000615	Eye Makeup Products?Eye makeup products, including mascaras, eyeliners, and eyeshadows, often contain a variety of synthetic chemicals such as pigments, preservatives, and film-forming agents.	Personal care & cosmetics	Not Available
CEDs000617	Lip Care Products?Lip care products, including lipsticks, balms, and glosses, often contain a variety of synthetic chemicals such as parabens, phthalates, and synthetic fragrances.	Personal care & cosmetics	Not Available
CEDs000618	Lip Makeup Products?Lip makeup products, such as lipsticks, lip glosses, and lip liners, often contain a variety of synthetic chemicals, including pigments, preservatives, and emollients.	Personal care & cosmetics	Not Available
CEDs000619	Manicure Pedicure?Manicure and pedicure procedures often involve the use of various synthetic chemicals, including solvents, nail polishes, and nail adhesives.	Personal care & cosmetics	Not Available
CEDs000632	Apparel?Apparel production often involves the use of various synthetic chemicals, including dyes, finishing agents, and preservatives.	Textiles, leather & furnishings	Not Available
CEDs000642	Footwear?Footwear production often involves the use of various synthetic chemicals, such as adhesives, dyes, and treatments, which can contribute to environmental contamination.	Textiles, leather & furnishings	Not Available
CEDs000643	Headwear?Headwear made from synthetic materials often incorporates chemicals used in the manufacturing and finishing processes, such as dyes, flame retardants, and water repellents.	Textiles, leather & furnishings	Not Available
CEDs000650	Purses Luggage Hand Bags?Purses, luggage, and handbags are often manufactured using synthetic materials such as polyvinyl chloride (PVC), polyurethane, and various types of nylon.	Textiles, leather & furnishings	Not Available
CEDs000652	Ropes?Ropes manufactured from synthetic fibers, such as polypropylene, nylon, and polyester, are widely used in various applications, including marine, construction, and outdoor activities.	Textiles, leather & furnishings	Not Available
CEDs000662	Yarns Or Threads?Yarns or threads used in textiles can be a source of synthetic chemical contamination due to the production processes and treatments they undergo.	Textiles, leather & furnishings	Not Available
CEDs000664	Fire Fighting Gels?Fire fighting gels are synthetic chemical formulations designed to enhance fire suppression effectiveness by creating a protective barrier against heat and flames.	Fire suppression systems & agents	Not Available
CEDs000667	Gaseous Fire Fighting?Gaseous fire fighting systems utilize synthetic chemicals, such as halocarbons and inert gases, to suppress fires through chemical and physical processes.	Fire suppression systems & agents	Not Available
CEDs000670	Solid Fire Fighting Substances?Solid fire fighting substances, such as certain types of dry chemical powders, are used in fire suppression applications to extinguish flames and prevent fire spread.	Fire suppression systems & agents	Not Available
CEDs000678	Nitrogenous Fertilisers?Nitrogenous fertilizers are synthetic chemical compounds primarily used to enhance plant growth by supplying essential nitrogen, a crucial nutrient for photosynthesis and protein synthesis.	Agriculture & land management	Not Available
CEDs000679	Phosphatic Fertilisers?Phosphatic fertilizers are synthetic chemical products primarily composed of phosphorus, which is essential for plant growth.	Agriculture & land management	Not Available
CEDs000684	Cements?Cements are a composite material primarily used as a binding agent in construction applications, formed by the calcination of limestone and clay minerals at high temperatures.	Building & Construction	Not Available
CEDs000685	Ceramics?Ceramics can be a source of synthetic chemical contamination through various additives and processing agents used in their production.	Building & Construction	Not Available
CEDs000686	Clay Wares?Clay wares are ceramic products made from natural clay, often utilized in various construction applications such as tiles, bricks, and sanitary ware.	Building & Construction	Not Available
CEDs000688	Glass Coatings?Glass coatings are synthetic chemical formulations applied to glass surfaces to enhance properties such as durability, UV resistance, and aesthetic appeal.	Building & Construction	Not Available
CEDs000691	Non Oxide Glass?Non-oxide glass refers to a category of glasses primarily composed of materials other than silicon dioxide, such as boron oxide or phosphorous oxide.	Building & Construction	Not Available
CEDs000692	Silica Free Oxide Glass?Silica Free Oxide Glass is a type of glass that is produced using alternative materials to traditional silica-based formulations.	Building & Construction	Not Available
CEDs000693	Silica Glass?Silica glass, primarily composed of silicon dioxide (SiO2), is widely used in various applications, including windows, glass facades, and insulation materials.	Building & Construction	Not Available
CEDs000696	Nanotechnology?Nanotechnology involves the manipulation of materials at the molecular or atomic level, typically within the range of 1 to 100 nanometers.	Industrial manufacturing & chemical processing	Not Available
CEDs000734	Coating Compositions?Coating compositions, which include paints, sealants, and varnishes, are formulated with a variety of synthetic chemicals such as solvents, resins, pigments, and additives.	Building & Construction	Not Available
CEDs000735	Explosives?Explosives are chemical compounds or mixtures designed to undergo rapid decomposition, releasing energy in the form of gas and heat.	Defense & military infrastructure	Not Available
CEDs000736	Fuses?Fuses are safety devices designed to protect electrical circuits by breaking the circuit when excessive current flows through.	Electrical & Electronic Equipment	Not Available
CEDs000738	Cooling Circuit Water?Cooling circuit water is utilized in various industrial processes to absorb and dissipate heat generated during operations.	Industrial manufacturing & chemical processing	Not Available
CEDs000739	Inks?Inks are complex mixtures composed of pigments or dyes, solvents, resins, and additives used primarily for printing and writing applications.	Paper, pulp & fiber products	Not Available
CEDs000740	Paper?Paper production involves the processing of wood fibers and the use of various chemicals, which can lead to synthetic chemical contamination.	Paper, pulp & fiber products	Not Available
CEDs000741	Pigment Pastes?Pigment pastes are concentrated dispersions of pigments used to impart color and properties to materials.	Paper, pulp & fiber products	Not Available
CEDs000743	Sludge Treatment?Sludge treatment involves the processing of waste materials generated from wastewater treatment plants, which often contain a variety of organic and inorganic substances.	Wastewater, sanitation & biosolids	Not Available
CEDs000744	Water, Wastewater, & Sewage Treatment?Water, wastewater, and sewage treatment processes are critical for managing and mitigating pollutants in water systems.	Wastewater, sanitation & biosolids	Not Available

Pathways

0 pathwaysPathway Source: PathBank

No pathways found

No metabolic pathways have been associated with this synthetic chemical

Targets

Structure	Protein	UniProt ID	Organism	Relationship	Details
Click to view 3D structure	Type IV secretion-like conjugative transfer relaxase protein TraI	B1LRJ1	Escherichia coli (strain SMS-3-5 / SECEC)	Predicted (SEA)	Prediction Confidence Score 0.067 Applicability Domain 0.067 Low confidence Statistical Significance 0.0442 Supporting Reference Compounds 1 E-value 344.094
Click to view 3D structure	NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial	P25708	Bos taurus	Predicted (SEA)	Prediction Confidence Score 0.067 Applicability Domain 0.067 Low confidence Statistical Significance 0.958 Supporting Reference Compounds 1 E-value 7457.72
Click to view 3D structure	Acetylcholinesterase	P22303	Humans	Predicted (SEA)	Prediction Confidence Score 0.055 Applicability Domain 0.083 Low confidence Statistical Significance 1.0 Supporting Reference Compounds 406 E-value 7784.69
Click to view 3D structure	Sphingosine 1-phosphate receptor 4	O95977	Humans	Predicted (SEA)	Prediction Confidence Score 0.053 Applicability Domain 0.069 Low confidence Statistical Significance 1.0 Supporting Reference Compounds 117 E-value 7784.61
Click to view 3D structure	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, chloroplastic	P69834	Arabidopsis thaliana	Predicted (SEA)	Prediction Confidence Score 0.053 Applicability Domain 0.053 Low confidence Statistical Significance 0.9744 Supporting Reference Compounds 1 E-value 7585.47
Click to view 3D structure	Liver carboxylesterase 1	P23141	Humans	Predicted (SEA)	Prediction Confidence Score 0.052 Applicability Domain 0.083 Low confidence Statistical Significance 0.9999 Supporting Reference Compounds 55 E-value 7784.22
Click to view 3D structure	Cholinesterase	P06276	Humans	Predicted (SEA)	Prediction Confidence Score 0.052 Applicability Domain 0.083 Low confidence Statistical Significance 1.0 Supporting Reference Compounds 234 E-value 7784.61
Click to view 3D structure	DEP domain-containing mTOR-interacting protein	Q8TB45	Humans	Predicted (SEA)	Prediction Confidence Score 0.051 Applicability Domain 0.063 Low confidence Statistical Significance 0.5215 Supporting Reference Compounds 2 E-value 4059.91
Click to view 3D structure	Protein RecA	P9WHJ3	Mycobacterium tuberculosis	Predicted (SEA)	Prediction Confidence Score 0.051 Applicability Domain 0.061 Low confidence Statistical Significance 1.0 Supporting Reference Compounds 296 E-value 7784.69
Click to view 3D structure	G-protein coupled receptor 35	Q9HC97	Humans	Predicted (SEA)	Prediction Confidence Score 0.05 Applicability Domain 0.073 Low confidence Statistical Significance 1.0 Supporting Reference Compounds 115 E-value 7784.69
Click to view 3D structure	DNA damage-inducible transcript 3 protein	P35639	Mus musculus	Predicted (SEA)	Prediction Confidence Score 0.05 Applicability Domain 0.069 Low confidence Statistical Significance 1.0 Supporting Reference Compounds 226 E-value 7784.61
Click to view 3D structure	X-box-binding protein 1	P17861	Humans	Predicted (SEA)	Prediction Confidence Score 0.05 Applicability Domain 0.069 Low confidence Statistical Significance 1.0 Supporting Reference Compounds 227 E-value 7784.61
Click to view 3D structure	Cytochrome P450 14alpha-demethylase	A1XG20	Penicillium digitatum	Predicted (SEA)	Prediction Confidence Score 0.05 Applicability Domain 0.05 Low confidence Statistical Significance 0.9946 Supporting Reference Compounds 3 E-value 7742.57
Click to view 3D structure	Replicase polyprotein 1ab	P0DTD1	SARS-CoV-2	Predicted (SEA)	Prediction Confidence Score 0.049 Applicability Domain 0.083 Low confidence Statistical Significance 1.0 Supporting Reference Compounds 215 E-value 7784.69
Click to view 3D structure	Acetylcholinesterase	Q9DDE3	Danio rerio	Predicted (SEA)	Prediction Confidence Score 0.049 Applicability Domain 0.049 Low confidence Statistical Significance 0.9769 Supporting Reference Compounds 1 E-value 7605.01
Click to view 3D structure	D(4) dopamine receptor	P21917	Humans	Predicted (SEA)	Prediction Confidence Score 0.048 Applicability Domain 0.049 Low confidence Statistical Significance 1.0 Supporting Reference Compounds 524 E-value 7784.61
Click to view 3D structure	Heat shock factor protein 1	P38532	Mus musculus	Predicted (SEA)	Prediction Confidence Score 0.048 Applicability Domain 0.069 Low confidence Statistical Significance 1.0 Supporting Reference Compounds 166 E-value 7784.61
Click to view 3D structure	5-hydroxytryptamine receptor 2A	P14842	Rattus norvegicus	Predicted (SEA)	Prediction Confidence Score 0.047 Applicability Domain 0.049 Low confidence Statistical Significance 1.0 Supporting Reference Compounds 380 E-value 7784.61
Click to view 3D structure	D(3) dopamine receptor	P35462	Humans	Predicted (SEA)	Prediction Confidence Score 0.047 Applicability Domain 0.049 Low confidence Statistical Significance 1.0 Supporting Reference Compounds 861 E-value 7784.69
Click to view 3D structure	ATP-dependent molecular chaperone HSP82	C4YTQ8	Candida albicans (strain WO-1) (Yeast)	Predicted (SEA)	Prediction Confidence Score 0.047 Applicability Domain 0.073 Low confidence Statistical Significance 1.0 Supporting Reference Compounds 205 E-value 7784.69
Click to view 3D structure	D(2) dopamine receptor	P61169	Rat	Predicted (SEA)	Prediction Confidence Score 0.047 Applicability Domain 0.049 Low confidence Statistical Significance 1.0 Supporting Reference Compounds 528 E-value 7784.61
Click to view 3D structure	5-hydroxytryptamine receptor 1A	P19327	Rattus norvegicus	Predicted (SEA)	Prediction Confidence Score 0.046 Applicability Domain 0.049 Low confidence Statistical Significance 1.0 Supporting Reference Compounds 541 E-value 7784.69
Click to view 3D structure	Histone acetyltransferase KAT2B	Q92831	Humans	Predicted (SEA)	Prediction Confidence Score 0.045 Applicability Domain 0.05 Low confidence Statistical Significance 0.9999 Supporting Reference Compounds 43 E-value 7784.3
Click to view 3D structure	Coenzyme A biosynthesis bifunctional protein CoaBC	P9WNZ1	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	Predicted (SEA)	Prediction Confidence Score 0.044 Applicability Domain 0.044 Low confidence Statistical Significance 0.9881 Supporting Reference Compounds 1 E-value 7692.28
Click to view 3D structure	Tyrosine-protein kinase Lck	P06239	Humans	Predicted (SEA)	Prediction Confidence Score 0.044 Applicability Domain 0.051 Low confidence Statistical Significance 1.0 Supporting Reference Compounds 1130 E-value 7784.69
Click to view 3D structure	Glutathione S-transferase A1	P08263	Humans	Known	Trivalent antimony inhibits glutathione-S-transferases from human erythrocytes, reducing their detoxification ability. (L137)
Click to view 3D structure	Glutathione S-transferase A2	P09210	Humans	Known	Trivalent antimony inhibits glutathione-S-transferases from human erythrocytes, reducing their detoxification ability. (L137)
Click to view 3D structure	Glutathione S-transferase A3	Q16772	Humans	Known	Trivalent antimony inhibits glutathione-S-transferases from human erythrocytes, reducing their detoxification ability. (L137)
Click to view 3D structure	Glutathione S-transferase A5	Q7RTV2	Humans	Known	Trivalent antimony inhibits glutathione-S-transferases from human erythrocytes, reducing their detoxification ability. (L137)
Click to view 3D structure	Glutathione S-transferase Mu 1	P09488	Humans	Known	Trivalent antimony inhibits glutathione-S-transferases from human erythrocytes, reducing their detoxification ability. (L137)
Click to view 3D structure	Glutathione S-transferase Mu 2	P28161	Humans	Known	Trivalent antimony inhibits glutathione-S-transferases from human erythrocytes, reducing their detoxification ability. (L137)
Click to view 3D structure	Glutathione S-transferase Mu 3	P21266	Humans	Known	Trivalent antimony inhibits glutathione-S-transferases from human erythrocytes, reducing their detoxification ability. (L137)
Click to view 3D structure	Glutathione S-transferase Mu 4	Q03013	Humans	Known	Trivalent antimony inhibits glutathione-S-transferases from human erythrocytes, reducing their detoxification ability. (L137)
Click to view 3D structure	Glutathione S-transferase Mu 5	P46439	Humans	Known	Trivalent antimony inhibits glutathione-S-transferases from human erythrocytes, reducing their detoxification ability. (L137)
Click to view 3D structure	Glutathione S-transferase P	P09211	Humans	Known	Trivalent antimony inhibits glutathione-S-transferases from human erythrocytes, reducing their detoxification ability. (L137)
Click to view 3D structure	Glutathione S-transferase kappa 1	Q9Y2Q3	Humans	Known	Trivalent antimony inhibits glutathione-S-transferases from human erythrocytes, reducing their detoxification ability. (L137)
Click to view 3D structure	Glutathione S-transferase omega-1	P78417	Humans	Known	Trivalent antimony inhibits glutathione-S-transferases from human erythrocytes, reducing their detoxification ability. (L137)
Click to view 3D structure	Glutathione S-transferase omega-2	Q9H4Y5	Humans	Known	Trivalent antimony inhibits glutathione-S-transferases from human erythrocytes, reducing their detoxification ability. (L137)
Click to view 3D structure	Glutathione S-transferase theta-1	P30711	Humans	Known	Trivalent antimony inhibits glutathione-S-transferases from human erythrocytes, reducing their detoxification ability. (L137)
Click to view 3D structure	Glutathione S-transferase theta-2	P0CG29	Humans	Known	Trivalent antimony inhibits glutathione-S-transferases from human erythrocytes, reducing their detoxification ability. (L137)
Click to view 3D structure	Maleylacetoacetate isomerase	O43708	Humans	Known	Trivalent antimony inhibits glutathione-S-transferases from human erythrocytes, reducing their detoxification ability. (L137)
Click to view 3D structure	Microsomal glutathione S-transferase 1	P10620	Humans	Known	Trivalent antimony inhibits glutathione-S-transferases from human erythrocytes, reducing their detoxification ability. (L137)
Click to view 3D structure	Microsomal glutathione S-transferase 2	Q99735	Humans	Known	Trivalent antimony inhibits glutathione-S-transferases from human erythrocytes, reducing their detoxification ability. (L137)
Click to view 3D structure	Glutathione S-transferase 3, mitochondrial	O14880	Humans	Known	Trivalent antimony inhibits glutathione-S-transferases from human erythrocytes, reducing their detoxification ability. (L137)

Concentrations

Not Available

External Links

DrugBank ID

Not Available

HMDB ID

Not Available

FooDB ID

Not Available

Phenol Explorer ID

Not Available

KNApSAcK ID

Not Available

BiGG ID

Not Available

BioCyc ID

Not Available

METLIN ID

Not Available

PDB ID

Not Available

Wikipedia Link

Antimony trichloride

Chemspider ID

Not Available

ChEBI ID

74856

PubChem Compound ID

24814

Kegg Compound ID

C15235

YMDB ID

Not Available

ECMDB ID

Not Available

References

Synthesis Reference

Not Available

MSDS

Not Available

General References

Poon R, Chu I, Lecavalier P, Valli VE, Foster W, Gupta S, Thomas B: Effects of antimony on rats following 90-day exposure via drinking water. Food Chem Toxicol. 1998 Jan;36(1):21-35. [PubMed: 9487361]
International Agency for Research on Cancer (2014). IARC Monographs on the Evaluation of Carcinogenic Risks to Humans. - http://monographs.iarc.fr/index.php
ATSDR - Agency for Toxic Substances and Disease Registry (1992). Toxicological profile for antimony. U.S. Public Health Service in collaboration with U.S. Environmental Protection Agency (EPA). - http://www.atsdr.cdc.gov/toxprofiles/tp23.html
Wikipedia. Antimony trichloride. Last Updated 16 June 2009. - http://en.wikipedia.org/wiki/Antimony_trichloride
The Physical and Theoretical Chemistry Laboratory of Oxford University (2005). Material Safety Data Sheet (MSDS) for antimony Tichloride. - http://msds.chem.ox.ac.uk/AN/antimony_III_chloride.html
Hayes WJ Jr. and Laws ER Jr. (eds) (1991). Handbook of Pesticide Toxicology. Volume 3. Classes of Pesticides. New York, NY: Academic Press, Inc.
Rumack BH (2009). POISINDEX(R) Information System. Englewood, CO: Micromedex, Inc. CCIS Volume 141, edition expires Aug, 2009.
Hamilton A and Hardy HL (1974). Industrial Toxicology. 3rd ed. Acton, MA: Publishing Sciences Group, Inc.

Antimony trichloride (CED0010540)

Structure for CHEM000751: Antimony trichloride

No pathways found

Structure