Pyridoxine (CED0001865)

Pyridoxine belongs to the pyridoxines, a subclass of pyridines and derivatives within the organic compounds. This endogenous human metabolite has the formula C8H11NO3 and an average molecular weight of 169.18 g/mol. At room temperature, the compound exists as a solid. It is detected in the liver and erythrocyte tissues and functions as a biological cofactor (PMC10573427). Pyridoxine is one of the compounds that can be called vitamin B6, a collective term that also includes pyridoxal and pyridoxamine, as well as their phosphorylated derivatives: pyridoxine 5'-phosphate, pyridoxal 5'-phosphate, and pyridoxamine 5'-phosphate. In the body, pyridoxine is converted to pyridoxal 5-phosphate, which serves as a coenzyme for the synthesis of sphingolipids, aminolevulinic acid, amino acids, and neurotransmitters such as norepinephrine and serotonin. Recorded protein targets for pyridoxine include Chronophin (PDXP), Pyridoxal kinase (PDXK), Cystathionine beta-synthase (CBS), and Phosphoserine aminotransferase (PSAT1), and it acts as a cofactor of Aromatic-L-amino-acid decarboxylase (DDC). Pyridoxine is found in vitamins and is recorded in various other sources, including food processing and cookware (such as the preparation of vinegar, food preservation, and fermentation processes for beer), household cleaning and consumer products (including perfumes within detergents and soaps, bleaching agents, and cigar cigarettes), building and construction materials (such as tents or canopies and ceilings), and electrical and electronic equipment (including amplifiers, antennas, and discharge lamps). Exposure routes include oral, intravenous, intramuscular, topical, transdermal, cutaneous, ophthalmic, and dental.