Econazole (CED0005931)

Econazole is an exogenous solid compound with the formula C18H15Cl3N2O and an average molecular weight of 381.68 g/mol. Econazole belongs to the benzylethers, a subclass of benzene and substituted derivatives within the organic compounds. It serves as an antifungal agent for biological application. The compound is found in 17 recorded sources, including healthcare, pharmaceuticals, and veterinary products such as antibiotics, gynecologicals, and antifungals for dermatological use. It is also present in food preservation, floors, and various household cleaning and consumer products, including soap detergents, perfumes within detergents and soaps, bleaching agents, cigar cigarettes, and other smoking requisites. Additionally, it is found in electrical and electronic equipment, including electrodes, hybrid capacitors, electric hearing aids, electrically stimulated smoking devices, and conductors or conductive bodies characterised by the conductive materials. Recorded exposure routes for the compound include oral, topical, vaginal, and inhalation. Econazole interacts with six recorded protein targets. These include lanosterol 14-alpha demethylase (CYP51A1), steroid 17-alpha-hydroxylase/17,20 lyase (CYP17A1), malate dehydrogenase, cytoplasmic (MDH1), and it acts as an antagonist/partial agonist of cytochrome P450 3A4 (CYP3A4), along with two other proteins.