Nitrous oxide (CED0001356)

Record Information
Version1.0
Creation Date2014-09-05 17:11:43 UTC
Update Date2026-05-14 18:22:54 UTC
SynCED IDCED0001356
Secondary Accession Numbers
  • CHEM003551
  • T3D4591
Identification
Common NameNitrous oxide
ClassSmall Molecule
Description
Nitrous oxide (N2O) is an inorganic gas with an average molecular weight of 44.01 g/mol. Nitrous oxide belongs to the other non-metal nitrides, a subclass of other non-metal organides within the inorganic compounds. This exogenous compound is utilized as a general anaesthetic, inhalation anaesthetic, vasodilator agent, and analgesic (PMC12500755 ). Biologically, it functions as an NMDA receptor antagonist, a bacterial metabolite, and an antidepressant (PMC12500755 ). It is used in the treatment of pain (PMC8017698 ) and depression (PMC12500755 ), showing a therapeutic effect on major depressive disorder (PMC12500755 ). However, it is associated with neuropathy (PMC1492602 ). Industrially, nitrous oxide serves as a reagent, an oxidising agent (PMC12175049 ), a refrigerant, and a non-motive propellant used as a blowing agent. It is used as a food propellant, a food packaging gas, a raising agent, and as a flavouring and nutrient (PMC12175049 ). In plastics, it is used in Polyamide. Environmentally, it is classified as a greenhouse gas (PMC10073400 , PMC12500755 ). Nitrous oxide is released from 34 recorded sources, including anesthetics in healthcare; fermentation processes for beer, food preservation, and the preparation of wine, sparkling wine, or wort in food processing; household cleaning products such as bleaching agents, soap detergents, and perfumes; electrical equipment including discharge lamps and antennas; and building materials like tents or canopies. Recorded exposure routes include rectal and respiratory, with inhalation supported by literature (PMC12161451 , PMC12500755 ).
Contaminant Type
  • Aerosol Spray Component
  • Flavouring Agent
  • Food Additive
  • Food Toxin
  • Household Toxin
  • Human Neurotoxin
  • Inorganic Compound
  • Metabolite
  • Non-Metal
  • Synthetic Compound
Chemical Structure
Synonyms
ValueSource
Diazyne 1-oxideChEBI
Dinitrogen monoxideChEBI
DistickstoffmonoxidChEBI
e942ChEBI
Factitious airChEBI
Gaz hilarantChEBI
LachgasChEBI
Laughing gasChEBI
N2OChEBI
Nitrogen protoxideChEBI
Nitrogenium oxydulatumChEBI
NNOChEBI
Oxyde nitreuxChEBI
Protoxyde d'azoteChEBI
R-744aChEBI
Stickstoff(I)-oxidChEBI
Dinitrogen oxideKegg
FEMA 2779HMDB
Gas, laughingHMDB
Hyponitrous acid anhydrideHMDB
NitralHMDB
Nitrogen hypoxideHMDB
Nitrogen monoxideHMDB
Nitrogen oxide (N2O)HMDB
Nitrous oxide (JP15/usp)HMDB
Nitrous oxide, compressedHMDB
Nitrous oxide, jan, usanHMDB
Nitrous oxide, refrigerated liquidHMDB
Nitrous-oxideHMDB
Oxide, nitrousHMDB
oxido NitrosoHMDB
Oxidodinitrogen(N--N)HMDB
StickdioxydHMDB
Nitrous oxideChEBI
Chemical FormulaN2O
Average Molecular Mass44.013 g/mol
Monoisotopic Mass44.001 g/mol
CAS Registry Number10024-97-2
IUPAC Namediazooxidane
Traditional Namenitrous oxide
SMILES[O-][N+]#N
InChI IdentifierInChI=1S/N2O/c1-2-3
InChI KeyGQPLMRYTRLFLPF-UHFFFAOYSA-N
Chemical Taxonomy
Description Belongs to the class of inorganic compounds known as other non-metal nitrides. These are inorganic compounds of nitrogen where nitrogen has a formal oxidation state of -3, and the heaviest atom bonded to it belongs to the class of 'other non-metals'.
KingdomInorganic compounds
Super ClassHomogeneous non-metal compounds
ClassOther non-metal organides
Sub ClassOther non-metal nitrides
Direct ParentOther non-metal nitrides
Alternative Parents
Substituents
  • Other non-metal nitride
  • Inorganic nitride
  • Inorganic oxide
Molecular FrameworkNot Available
External Descriptors
Biological Properties
StatusDetected and Not Quantified
OriginExogenous
Cellular Locations
  • Cytoplasm
  • Extracellular
Biofluid LocationsNot Available
Tissue LocationsNot Available
Applications
Biological Roles
Chemical Roles
  • greenhouse gas ?A chemical substance in gaseous form, which is released to the atmosphere and contributes to the greenhouse effect by absorbing and emitting radiation within the thermal infrared range.
Organoleptic Effects
  • colorless colour ?
  • sweet odour ?
  • offensive odor odour ?
Physical Properties
StateGas
AppearanceNot Available
Experimental Properties
PropertyValue
Melting Point-90.6 °C
Boiling Point-88.48°C (184.67°K)
SolubilityNot Available
Predicted Properties
PropertyValueSource
logP-0.021ChemAxon
pKa (Strongest Basic)-6.8ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count3ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area54.46 ŲChemAxon
Rotatable Bond Count0ChemAxon
Refractivity27.67 m³·mol⁻¹ChemAxon
Polarizability2.54 ųChemAxon
Number of Rings0ChemAxon
BioavailabilityYesChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon
Spectra
Spectra
Spectrum TypeDescriptionSplash KeyDeposition DateView
Predicted GC-MSPredicted GC-MS Spectrumsplash10-0006-9000000000-eb7b02e9ea0e132b0a58Not AvailableView Spectrum
Predicted GC-MSPredicted GC-MS SpectrumNot AvailableNot AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-0002-9000000000-2eee7435817186856ef7Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-001j-9000000000-d1a5381e3dd214cad7abNot AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-000t-9000000000-3ae2e01e3d626729760bNot AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-004l-9000000000-c53ff0d270e0310b3375Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-004i-9000000000-c8b9d8f80d3f41ad7f54Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-002f-9000000000-12c3fe456373daff732eNot AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-0002-9000000000-f78d84fc2eb278e7bb4dNot AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-0002-9000000000-f78d84fc2eb278e7bb4dNot AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-0002-9000000000-f78d84fc2eb278e7bb4dNot AvailableView Spectrum
Toxicity Profile
Toxicity ValuesNot Available
Toxicity / Toxin ClassNot Available
Mechanism of ToxicityNot Available
Carcinogenicity (IARC Classification)No indication of carcinogenicity to humans (not listed by IARC).
Minimum Risk LevelNot Available
SymptomsNot Available
TreatmentNot Available
Health Effects
Health EffectRelationshipDirectionDescriptionReference
lung cancerAssociated With?Not AvailableA respiratory system cancer that is located in the lung. (DO)PMC6612795
lung cancerAssociated With?increaseA respiratory system cancer that is located in the lung. (DO)PMC5981873
asthmaAssociated With?increaseA bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has symptom recurring periods of wheezing (a whistling sound while breathing), has symptom chest tightness, has symptom shortness of breath, has symptom mucus production and has symptom coughing. The symptoms appear due to a variety of triggers such as allergens, irritants, respiratory infections, weather changes, exercise, stress, reflux disease, medications, foods and emotional anxiety. (DO)PMC5981873
asthmaAssociated With?Not AvailableA bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has symptom recurring periods of wheezing (a whistling sound while breathing), has symptom chest tightness, has symptom shortness of breath, has symptom mucus production and has symptom coughing. The symptoms appear due to a variety of triggers such as allergens, irritants, respiratory infections, weather changes, exercise, stress, reflux disease, medications, foods and emotional anxiety. (DO)PMC12121063
painNot AvailableNot AvailableA disorder characterized by the sensation of marked discomfort, distress or agony. (NCI CTCAE)PMC8017698
painHas Therapeutic Effect OnNot AvailableA disorder characterized by the sensation of marked discomfort, distress or agony. (NCI CTCAE)PMC7850687 , PMC7850687
depressionNot AvailableNot AvailableNot AvailablePMC12500755
psoriasisAssociated With?Not AvailableA disorder characterized by a quicker life span of skin cells causing cells to build up rapidly on the surface of the skin.PMC13219715
psoriasisAssociated With?increaseA disorder characterized by a quicker life span of skin cells causing cells to build up rapidly on the surface of the skin.PMC13219715
COVID-19Associated With?Not AvailableNot AvailablePMC9157479 , PMC9157479
nauseaAssociated With?Not AvailableA disorder characterized by a queasy sensation and/or the urge to vomit. (NCI CTCAE)PMC7449136
vomitingAssociated With?Not AvailableA disorder characterized by the reflexive act of ejecting the contents of the stomach through the mouth. (NCI CTCAE)PMC7449136
heart failureAssociated With?Not AvailableA disorder characterized by the inability of the heart to pump blood at an adequate volume to meet tissue metabolic requirements, or, the ability to do so only at an elevation in the filling pressure. (NCI CTCAE)PMC12121063
goutAssociated With?increaseAn arthritis that has material basis in uric acid crystal deposits located in joint. (DO)PMC13307085
heart diseaseAssociated With?Not AvailableA cardiovascular system disease that involves the heart. (DO)PMC6068494
neuropathyAssociated With?Not AvailableA nervous system disease that is located in nerves or nerve cells. (do).PMC1492602
dermatitisAssociated With?Not AvailableNot AvailablePMC8702460
Chronic Obstructive Pulmonary DiseaseAssociated With?increaseA disorder characterized by long-term breathing problems and poor airflow, commonly attributed to smoking.PMC5981873
miscarriageAssociated With?Not AvailableA natural death of an embryo or fetus before it is able to survive independently.PMC7038808
arrhythmiaAssociated With?Not AvailableNot AvailablePMC12121063
acute myocardial infarctionAssociated With?Not AvailableNot AvailablePMC12121063
major depressive disorderHas Therapeutic Effect OnNot AvailableAn endogenous depression that is characterized by an all-encompassing low mood accompanied by low self-esteem, and by loss of interest or pleasure in normally enjoyable activities. (DO)PMC12500755
major depressive disorderNot AvailableNot AvailableAn endogenous depression that is characterized by an all-encompassing low mood accompanied by low self-esteem, and by loss of interest or pleasure in normally enjoyable activities. (DO)PMC12500755
allergic asthmaAssociated With?increaseNot AvailablePMC8215519
basal cell carcinomaNot AvailableNot AvailableA skin carcinoma affecting basal cells.PMC9275133
meningococcal meningitisAssociated With?increaseNot AvailablePMC12751527
kidney cancerAssociated With?Not AvailableA urinary system cancer that is located in the kidney. (DO)PMC12986066
varicoceleAssociated With?Not AvailableNot AvailablePMC4770490
cardiovascular disorderAssociated With?increaseNot AvailablePMC13470788 , PMC12121063
MortalityAssociated With?Not AvailableNot AvailablePMC11223482 , PMC11223482
MortalityAssociated With?decreaseNot AvailablePMC3673189
DeathAssociated With?decreaseNot AvailablePMC3673189
depressive disorderNot AvailableNot AvailableNot AvailablePMC12500755
PoisoningAssociated With?Not AvailableNot AvailablePMC10537912
AnesthesiaNot AvailableNot AvailableNot AvailablePMC7850687
fetal growth restrictionAssociated With?increaseNot AvailablePMC12753933
Anesthesia, GeneralAssociated With?Not AvailableNot AvailablePMC13456389
Respiratory Tract InfectionsAssociated With?increaseNot AvailablePMC5981873
pain agnosiaAssociated With?Not AvailableNot AvailablePMC13456389
respiratory system disorderAssociated With?Not AvailableNot AvailablePMC6068494
Respiratory Distress SyndromeAssociated With?increaseNot AvailablePMC12753933
AsphyxiaAssociated With?Not AvailableNot AvailablePMC10537912 , PMC12500755
IncidenceAssociated With?increaseNot AvailablePMC8215519
EmbolismAssociated With?Not AvailableNot AvailablePMC12121063
LaughterAssociated With?Not AvailableNot AvailablePMC12500755
Arterial thrombosisAssociated With?Not AvailableNot AvailablePMC12121063
scrub typhusAssociated With?Not AvailableNot AvailablePMC12121197 , PMC12121197
Procedural SedationAssociated With?Not AvailableNot AvailablePMC13456389
Carcinoma, Squamous CellNot AvailableNot AvailableNot AvailablePMC9275133
Exposure Sources
Source IDSourceSectorReference
CEDs000001Manure?Manure, a byproduct of livestock farming, is commonly used as a fertilizer in agricultural practices.Agriculture & land managementPMC5945976 , PMC13071492
CEDs000010Insecticides?Insecticides are synthetic chemicals designed to control or eliminate insect pests that threaten crops and other agricultural products.Agriculture & land managementPubChem
CEDs000013Soil?Soil serves as a critical medium for plant growth and sustains various ecological functions; however, it can become a reservoir for synthetic chemical contamination.Agriculture & land managementPMC149861 , PMC8397574
CEDs000014Compost?Compost, while primarily used as an organic soil amendment to enhance fertility and improve soil structure, can become a source of synthetic chemical contamination.Agriculture & land managementPMC9077033 , PMC9077033
CEDs000050Groundwater?Groundwater serves as a vital resource for drinking water and agricultural irrigation but is increasingly susceptible to contamination from synthetic chemicals.Aquatic systems & sedimentsPMC8024649 , PMC4374930
CEDs000051Surface water?Surface water can serve as a significant vector for the introduction of synthetic chemical contaminants into aquatic ecosystems.Aquatic systems & sedimentsPMC4374930
CEDs000070Stormwater runoff?Stormwater runoff refers to the flow of rainwater or melted snow that does not soak into the ground and instead collects pollutants as it travels over impervious surfaces such as roads and parking lots.Automotive & urban infrastructurePubChem
CEDs000181Ballast water?Ballast water, taken on by ships to maintain stability and balance, often contains a diverse array of microorganisms, including bacteria, viruses, and plankton.Marine, shipping & aquaculturePubChem
CEDs000182Bilge water?Bilge water is a byproduct generated from the accumulation of water in the lowest part of a ship's hull, which may include a mixture of seawater, oil, fuel residues, and various contaminants.Marine, shipping & aquaculturePubChem
CEDs000233Brushes?Brushes used in personal care and cosmetics can be a source of synthetic chemical contamination due to the materials and coatings used in their manufacturing.Personal care & cosmeticsPubChem
CEDs000369Anesthetics?Anesthetics are synthetic chemicals used to induce loss of sensation or consciousness in patients undergoing medical procedures.Healthcare, pharmaceuticals & veterinary productsNot Available
CEDs000469Sewage sludge?Sewage sludge is a byproduct generated during the treatment of wastewater in municipal and industrial processes.Wastewater, sanitation & biosolidsPMC8830992
CEDs000484Activated sludge?Activated sludge refers to a mixture of microorganisms and organic matter used in the biological treatment of wastewater.Wastewater, sanitation & biosolidsPMC8280996
CEDs000490Personal care & cosmeticsNot Available
CEDs000503Tents Or Canopies?Tents and canopies used in various applications can be a source of synthetic chemical contamination primarily due to the materials from which they are made.Building & ConstructionPubChem
CEDs000506Antennas?Antennas, commonly used in communication technologies, can be a source of synthetic chemical contamination through the materials and coatings used in their construction.Electrical & Electronic EquipmentPubChem
CEDs000508Coils?Coils are components used in various electrical and electronic applications, such as transformers, inductors, and motors.Electrical & Electronic EquipmentPubChem
CEDs000511Conductors Or Conductive Bodies Characterised By The Conductive Materials?Conductors, or conductive bodies, are materials that allow the flow of electrical current, typically made from metals such as copper, aluminum, or silver.Electrical & Electronic EquipmentPubChem
CEDs000514Discharge Lamps?Discharge lamps, including fluorescent and high-intensity discharge (HID) lamps, are commonly used for lighting applications due to their energy efficiency and brightness.Electrical & Electronic EquipmentPubChem
CEDs000516Electric Hearing Aids?Electric hearing aids are small electronic devices designed to amplify sound for individuals with hearing loss.Electrical & Electronic EquipmentPubChem
CEDs000517Electric Switches?Electric switches, integral components in numerous devices, can be a source of synthetic chemical contamination due to the materials and manufacturing processes involved in their production.Electrical & Electronic EquipmentPubChem
CEDs000518Electrically Stimulated Smoking Devices?Electrically stimulated smoking devices, commonly known as e-cigarettes or vape pens, utilize electrical components to heat a liquid solution, often containing nicotine, flavorings, and other additives, to produce an aerosol for inhalation.Electrical & Electronic EquipmentPubChem
CEDs000519Electrodes?Electrodes, used in various electrical and electronic applications, can be a source of synthetic chemical contamination due to the materials from which they are constructed and the processes involved in their manufacturing.Electrical & Electronic EquipmentPubChem
CEDs000521Fixed Capacitors And Their Manufacture?Fixed capacitors are passive electronic components used to store and release electrical energy, playing a critical role in various circuits.Electrical & Electronic EquipmentPubChem
CEDs000524Hybrid Capacitors?Hybrid capacitors are energy storage devices that combine the properties of electrolytic and supercapacitors, utilizing a combination of electrochemical principles to achieve higher energy density and power density.Electrical & Electronic EquipmentPubChem
CEDs000529Power Cables?Power cables are used to transmit electrical energy and are typically composed of conductive materials, insulation, and protective coatings.Electrical & Electronic EquipmentPubChem
CEDs000530Radio Transmission Systems?Radio transmission systems utilize a variety of synthetic chemicals in their manufacturing and maintenance processes.Electrical & Electronic EquipmentPubChem
CEDs000531Relays?Relays are electromechanical switches used to control circuits and manage electrical loads.Electrical & Electronic EquipmentPubChem
CEDs000533Sparking Plugs?Spark plugs are critical components in internal combustion engines, facilitating the ignition of fuel-air mixtures by generating a spark.Electrical & Electronic EquipmentPubChem
CEDs000534Still Video Cameras?Still video cameras, which capture images in digital format, can be a source of synthetic chemical contamination due to the materials and components used in their production and operation.Electrical & Electronic EquipmentPubChem
CEDs000536Superconductive Or Hyperconductive Conductors Cables Or Transmission Lines?Superconductive or hyperconductive conductors, including cables and transmission lines, are materials that exhibit zero electrical resistance under specific conditions, typically at low temperatures.Electrical & Electronic EquipmentPubChem
CEDs000537Television Systems?Television systems can be a source of synthetic chemical contamination due to the various materials and components used in their manufacture and operation.Electrical & Electronic EquipmentPubChem
CEDs000538Thin Magnetic Films?Thin magnetic films are layers of magnetic material ranging from a few nanometers to several micrometers in thickness, commonly used in applications such as magnetic sensors, data storage devices, and electronic components.Electrical & Electronic EquipmentPubChem
CEDs000539Video Games?Video games, through their production and disposal processes, can be a source of synthetic chemical contamination.Electrical & Electronic EquipmentPubChem
CEDs000544Fermentation Processes For Beer?Fermentation processes for beer involve the conversion of sugars into alcohol and carbon dioxide by yeast.Food, food processing & cookwarePubChem
CEDs000545Food Preservation?Food preservation often involves the use of synthetic chemicals, such as preservatives, flavor enhancers, and color additives, to extend shelf life and enhance the sensory qualities of food products.Food, food processing & cookwarePubChem
CEDs000549Preparation Of Wine Or Sparkling Wine?The preparation of wine or sparkling wine involves various stages, including fermentation, aging, and bottling, which can introduce potential sources of synthetic chemical contamination.Food, food processing & cookwarePubChem
CEDs000550Preparation Of Wort?The preparation of wort involves the extraction of sugars from malted grains, a crucial step in the brewing process.Food, food processing & cookwarePubChem
CEDs000552Processing Meats?Processing meats can lead to synthetic chemical contamination primarily through the use of additives and preservatives.Food, food processing & cookwarePubChem
CEDs000553Treatment Of Hops?Hops, a key ingredient in brewing and food flavoring, can be a source of synthetic chemical contamination due to various agricultural practices.Food, food processing & cookwarePubChem
CEDs000555Bleaching Agents?Bleaching agents are chemical substances used to whiten or lighten materials, often employed in various cleaning products for their stain removal and disinfecting properties.Household cleaning & consumer productsPubChem
CEDs000556Cigar Cigarettes?Cigar cigarettes are a source of synthetic chemical contamination due to the combustion of various tobacco blends and additives.Household cleaning & consumer productsPubChem
CEDs000559Non Electric Simulated Smoking Devices?Non-electric simulated smoking devices, often designed to mimic the experience of smoking without combustion, can be sources of synthetic chemical contamination due to the materials and chemicals used in their construction and operation.Household cleaning & consumer productsPubChem
CEDs000561Perfumes Within Detergents And Soaps?Perfumes within detergents and soaps are synthetic fragrance compounds added to enhance the sensory experience of cleaning products.Household cleaning & consumer productsPubChem
CEDs000563Soap Detergents?Soap detergents are synthetic surfactants designed to enhance the cleaning efficacy of water by reducing surface tension, allowing for better interaction with dirt and grease.Household cleaning & consumer productsPubChem
CEDs000564Soap Dispensers?Soap dispensers, commonly used for dispensing liquid soaps and sanitizers, can become a source of synthetic chemical contamination due to the materials used in their construction and the products they dispense.Household cleaning & consumer productsPubChem
CEDs000569Tobacco Smoke Filters?Tobacco smoke filters are designed to reduce the inhalation of harmful substances in cigarette smoke, including tar and other particulate matter.Household cleaning & consumer productsPubChem
CEDs000578Making Cigars?The process of making cigars involves several steps, including the cultivation of tobacco, fermentation, and the application of various additives to enhance flavor and preservation.Industrial manufacturing & chemical processingPubChem
CEDs000579Manufacture Of Iron Or Steel?The manufacture of iron or steel involves various processes, including smelting, refining, and alloying, which can result in the release of synthetic chemicals and contaminants.Industrial manufacturing & chemical processingPubChem
CEDs000580Manufacture Preparation Of Tobacco Products?The manufacture and preparation of tobacco products involve various processes that can result in the introduction of synthetic chemicals into the environment.Industrial manufacturing & chemical processingPubChem
CEDs000581Paper Making Machines?Paper making machines utilize various synthetic chemicals throughout the production process, including additives, coatings, and bleaching agents.Industrial manufacturing & chemical processingPubChem
CEDs000583Anchoring Equipment?Anchoring equipment, commonly used in marine applications, can be a source of synthetic chemical contamination due to the materials and coatings utilized in their manufacturing.Marine, shipping & aquaculturePubChem
CEDs000589Life Buoys?Life buoys, commonly used in marine environments for safety and rescue operations, can be a source of synthetic chemical contamination due to the materials used in their production.Marine, shipping & aquaculturePubChem
CEDs000592Marine Propulsion Or Steering?Marine propulsion and steering systems often rely on various synthetic chemicals, including lubricants, fuels, and hydraulic fluids.Marine, shipping & aquaculturePubChem
CEDs000594Ship Hulls?Ship hulls are often treated with various synthetic chemicals to enhance durability, prevent corrosion, and inhibit the growth of marine organisms.Marine, shipping & aquaculturePubChem
CEDs000595Ships?Ships, as vehicles for international trade and transportation, can be significant sources of synthetic chemical contamination in marine environments.Marine, shipping & aquaculturePubChem
CEDs000598Fertiliser Distributors?Fertiliser distributors play a critical role in the supply of synthetic fertilizers, which are widely used to enhance soil fertility and crop yield.Agriculture & land managementPubChem
CEDs000606Plant Growth Regulators?Plant Growth Regulators (PGRs) are synthetic chemicals designed to influence the growth and development of plants.Agriculture & land managementPubChem
CEDs000610Aftersun Products?Aftersun products are designed to soothe and hydrate the skin after sun exposure, often containing various synthetic chemicals such as emollients, preservatives, and fragrances.Personal care & cosmeticsPubChem
CEDs000611Anti Perspirants Or Body Deoderants?Antiperspirants and body deodorants commonly contain synthetic chemicals such as aluminum compounds, parabens, and synthetic fragrances.Personal care & cosmeticsPubChem
CEDs000614Essential Oils Or Perfumes?Essential oils and perfumes are complex mixtures of volatile compounds derived from natural or synthetic sources, commonly used for their aromatic properties.Personal care & cosmeticsPubChem
CEDs000615Eye Makeup Products?Eye makeup products, including mascaras, eyeliners, and eyeshadows, often contain a variety of synthetic chemicals such as pigments, preservatives, and film-forming agents.Personal care & cosmeticsPubChem
CEDs000618Lip Makeup Products?Lip makeup products, such as lipsticks, lip glosses, and lip liners, often contain a variety of synthetic chemicals, including pigments, preservatives, and emollients.Personal care & cosmeticsPubChem
CEDs000620Card Games?Card games often utilize synthetic materials for playing cards and associated gaming equipment, which may contain various chemicals such as polyvinyl chloride (PVC), plastics, and dyes.Recreation & sports surfacesPubChem
CEDs000630Toys?Toys, particularly those made from synthetic materials such as plastics, can be a source of chemical contamination due to the presence of various additives and compounds used in their production.Recreation & sports surfacesPubChem
CEDs000632Apparel?Apparel production often involves the use of various synthetic chemicals, including dyes, finishing agents, and preservatives.Textiles, leather & furnishingsPubChem
CEDs000633Azo Dyes?Azo dyes are synthetic organic compounds characterized by the presence of one or more azo groups (-N=N-), which are widely used for coloring textiles, leather, and furnishings.Textiles, leather & furnishingsPubChem
CEDs000642Footwear?Footwear production often involves the use of various synthetic chemicals, such as adhesives, dyes, and treatments, which can contribute to environmental contamination.Textiles, leather & furnishingsPubChem
CEDs000643Headwear?Headwear made from synthetic materials often incorporates chemicals used in the manufacturing and finishing processes, such as dyes, flame retardants, and water repellents.Textiles, leather & furnishingsPubChem
CEDs000652Ropes?Ropes manufactured from synthetic fibers, such as polypropylene, nylon, and polyester, are widely used in various applications, including marine, construction, and outdoor activities.Textiles, leather & furnishingsPubChem
CEDs000657Surface Finishing Of Leather?Surface finishing of leather often involves the use of various synthetic chemicals, including dyes, resins, and finishing agents.Textiles, leather & furnishingsPubChem
CEDs000662Yarns Or Threads?Yarns or threads used in textiles can be a source of synthetic chemical contamination due to the production processes and treatments they undergo.Textiles, leather & furnishingsPubChem
CEDs000665Fire Extinguishers?Fire extinguishers contain various synthetic chemicals designed to suppress flames and prevent the spread of fire.Fire suppression systems & agentsPubChem
CEDs000666Flame Traps?Flame traps are devices designed to prevent the propagation of flames and explosions by allowing gases to escape while blocking flames.Fire suppression systems & agentsPubChem
CEDs000667Gaseous Fire Fighting?Gaseous fire fighting systems utilize synthetic chemicals, such as halocarbons and inert gases, to suppress fires through chemical and physical processes.Fire suppression systems & agentsPubChem
CEDs000671Airplanes And Helicopters?Airplanes and helicopters are significant sources of synthetic chemical contamination primarily through the use of aviation fuels, lubricants, and de-icing agents.Aviation & AerospacePubChem
CEDs000673Unmanned Aerial Vehicles?Unmanned Aerial Vehicles (UAVs), commonly known as drones, utilize various synthetic chemicals in their manufacturing, operation, and maintenance processes.Aviation & AerospacePubChem
CEDs000678Nitrogenous Fertilisers?Nitrogenous fertilizers are synthetic chemical compounds primarily used to enhance plant growth by supplying essential nitrogen, a crucial nutrient for photosynthesis and protein synthesis.Agriculture & land managementPubChem
CEDs000679Phosphatic Fertilisers?Phosphatic fertilizers are synthetic chemical products primarily composed of phosphorus, which is essential for plant growth.Agriculture & land managementPubChem
CEDs000684Cements?Cements are a composite material primarily used as a binding agent in construction applications, formed by the calcination of limestone and clay minerals at high temperatures.Building & ConstructionPubChem
CEDs000685Ceramics?Ceramics can be a source of synthetic chemical contamination through various additives and processing agents used in their production.Building & ConstructionPubChem
CEDs000686Clay Wares?Clay wares are ceramic products made from natural clay, often utilized in various construction applications such as tiles, bricks, and sanitary ware.Building & ConstructionPubChem
CEDs000688Glass Coatings?Glass coatings are synthetic chemical formulations applied to glass surfaces to enhance properties such as durability, UV resistance, and aesthetic appeal.Building & ConstructionPubChem
CEDs000693Silica Glass?Silica glass, primarily composed of silicon dioxide (SiO2), is widely used in various applications, including windows, glass facades, and insulation materials.Building & ConstructionPubChem
CEDs000695Treatment Of Milk Or Cream?The treatment of milk or cream involves various processes such as pasteurization, homogenization, and the addition of preservatives to enhance shelf life and safety.Food, food processing & cookwarePubChem
CEDs000696Nanotechnology?Nanotechnology involves the manipulation of materials at the molecular or atomic level, typically within the range of 1 to 100 nanometers.Industrial manufacturing & chemical processingPubChem
CEDs000697Submarines?Submarines, while essential for military and research purposes, can be a source of synthetic chemical contamination due to their use of various industrial chemicals.Marine, shipping & aquaculturePubChem
CEDs000698Jewellery?Jewellery production often involves the use of various synthetic chemicals during the extraction and processing of metals.Mining & metal processingPubChem
CEDs000699Mining Or Quarrying?Mining and quarrying operations can lead to synthetic chemical contamination through the release of various pollutants associated with the extraction and processing of minerals.Mining & metal processingPubChem
CEDs000701Ventilation Of Mines Or Tunnels?Ventilation in mines or tunnels is essential for maintaining air quality and ensuring the safety of workers.Mining & metal processingPubChem
CEDs000727Printing Machines Or Presses?Printing machines or presses commonly utilize synthetic chemicals such as inks, solvents, and cleaning agents.Paper, pulp & fiber productsPubChem
CEDs000729Stamps?Stamps, particularly those produced using synthetic inks and adhesives, can contribute to chemical contamination when disposed of improperly.Paper, pulp & fiber productsPubChem
CEDs000734Coating Compositions?Coating compositions, which include paints, sealants, and varnishes, are formulated with a variety of synthetic chemicals such as solvents, resins, pigments, and additives.Building & ConstructionPubChem
CEDs000735Explosives?Explosives are chemical compounds or mixtures designed to undergo rapid decomposition, releasing energy in the form of gas and heat.Defense & military infrastructurePubChem
CEDs000737Chemical Igniters?Chemical igniters are substances or devices designed to initiate combustion in various applications, often found in products like lighters, candles, and certain household cleaning agents.Household itemsPubChem
CEDs000738Cooling Circuit Water?Cooling circuit water is utilized in various industrial processes to absorb and dissipate heat generated during operations.Industrial manufacturing & chemical processingPubChem
CEDs000739Inks?Inks are complex mixtures composed of pigments or dyes, solvents, resins, and additives used primarily for printing and writing applications.Paper, pulp & fiber productsPubChem
CEDs000740Paper?Paper production involves the processing of wood fibers and the use of various chemicals, which can lead to synthetic chemical contamination.Paper, pulp & fiber productsPubChem
CEDs000741Pigment Pastes?Pigment pastes are concentrated dispersions of pigments used to impart color and properties to materials.Paper, pulp & fiber productsPubChem
CEDs000742Leather Tanning?Leather tanning is a process that transforms raw animal hides into durable leather through the application of various chemicals, including chromium salts, aldehydes, and vegetable tannins.Textiles, leather & furnishingsPubChem
CEDs000743Sludge Treatment?Sludge treatment involves the processing of waste materials generated from wastewater treatment plants, which often contain a variety of organic and inorganic substances.Wastewater, sanitation & biosolidsPubChem
CEDs000744Water, Wastewater, & Sewage Treatment?Water, wastewater, and sewage treatment processes are critical for managing and mitigating pollutants in water systems.Wastewater, sanitation & biosolidsPubChem
CEDs00753Agricultural SoilAgriculture & land managementPMC11694899 , PMC6064718
CEDs00754BiocharAgriculture & land managementPMC9077033 , PMC9077033
CEDs00758Agricultural FieldAgriculture & land managementPMC2679592
CEDs00764Surface SoilAgriculture & land managementPMC9908017
CEDs00767FertilizersAgriculture & land managementPMC12768322
CEDs00770Animal ManureAgriculture & land managementPMC12121197
CEDs00806Agricultural CropsAgriculture & land managementPMC8807015
CEDs00810CroplandsAgriculture & land managementPMC13071492 , PMC13071492
CEDs00845Arable SoilAgriculture & land managementPMC13162411 , PMC2935130
CEDs00850Soil ProfileAgriculture & land managementPMC4374930
CEDs00898Forest SoilAgriculture & land managementPMC12488026 , PMC12488026
CEDs00924AgricultureAgriculture & land managementPMC4374930 , PMC12488026
CEDs00925Paddy SoilsAgriculture & land managementPMC13071492
CEDs00967Grassland EcosystemAgriculture & land managementPMC12488026 , PMC12488026
CEDs00975Agricultural LandsAgriculture & land managementPMC9908017
CEDs00978Cattle ManureAgriculture & land managementPMC12874676
CEDs00981Soil SystemsAgriculture & land managementPMC7182530
CEDs01004FarmlandsAgriculture & land managementPMC8809956
CEDs01009CroplandAgriculture & land managementPMC13071492 , PMC13071492
CEDs01010Upland SoilAgriculture & land managementPMC13071492
CEDs01029Natural SoilAgriculture & land managementPMC12488026
CEDs01058Farm DamsAgriculture & land managementPMC12874676 , PMC12874676
CEDs01066Agricultural SystemsAgriculture & land managementPMC11579327
CEDs01348Rice StrawFood, food processing & cookwarePMC12197902
CEDs02067LandfillWaste management, landfill & incinerationPMC12608835
CEDs02069Solid WasteWaste management, landfill & incinerationPMC10182749
CEDs02073RefuseWaste management, landfill & incinerationPMC5264584
CEDs02074Animal WasteWaste management, landfill & incinerationPMC8807015
CEDs02079Plastic WasteWaste management, landfill & incinerationPMC8941171
CEDs02082Waste GasWaste management, landfill & incinerationPMC12309966 , PMC12309966
CEDs02106Municipal Solid WasteWaste management, landfill & incinerationPMC9088909
CEDs02181BiowastesWaste management, landfill & incinerationPMC9160353
CEDs02255WaterAquatic systems & sedimentsPMC7094828 , PMC11021396
CEDs02256Marine EnvironmentAquatic systems & sedimentsPMC4374930 , PMC4374930
CEDs02257WatersAquatic systems & sedimentsPMC12488026 , PMC12488026
CEDs02260Aquatic SystemsAquatic systems & sedimentsPMC2929206 , PMC12488026
CEDs02261Sea WaterAquatic systems & sedimentsPMC6923134
CEDs02264SedimentAquatic systems & sedimentsPMC11223495 , PMC8024649
CEDs02268Water SamplesAquatic systems & sedimentsPMC11745158 , PMC11523617
CEDs02270RiverAquatic systems & sedimentsPMC11745158 , PMC11745158
CEDs02272Open OceanAquatic systems & sedimentsPMC11324526
CEDs02280OceanAquatic systems & sedimentsPMC4374930 , PMC4374930
CEDs02286LakeAquatic systems & sedimentsPMC11745158
CEDs02289StreamAquatic systems & sedimentsPMC10061935
CEDs02293Fresh WaterAquatic systems & sedimentsPMC4374930 , PMC4374930
CEDs02298Aquatic EcosystemAquatic systems & sedimentsPMC7418111
CEDs02309Wetland EcosystemAquatic systems & sedimentsPMC7994627 , PMC9522034
CEDs02314Pacific OceanAquatic systems & sedimentsPMC6923134
CEDs02319Lake WaterAquatic systems & sedimentsPMC6923134
CEDs02341LagoonAquatic systems & sedimentsPMC7416595
CEDs02344MarineAquatic systems & sedimentsPMC4374930 , PMC4374930
CEDs02380EstuaryAquatic systems & sedimentsPMC7994627 , PMC7994627
CEDs02395Constructed WetlandsAquatic systems & sedimentsPMC10861785 , PMC5511289
CEDs02398Mangrove SedimentsAquatic systems & sedimentsPMC3358729
CEDs02431Estuarine SedimentAquatic systems & sedimentsPMC7994627
CEDs02435Coastal OceanAquatic systems & sedimentsPMC7360760
CEDs02441Freshwater SamplesAquatic systems & sedimentsPMC11745158
CEDs02454Coastal SedimentAquatic systems & sedimentsPMC11051833
CEDs02458Rhine RiverAquatic systems & sedimentsPMC11512915 , PMC11512915
CEDs02503Coastal ZonesAquatic systems & sedimentsPMC4374930 , PMC4374930
CEDs02567Coastal WetlandsAquatic systems & sedimentsPMC9522034
CEDs02589AirAir, dust & atmospheric transportPMC10548484 , PMC11083012
CEDs02591AtmosphereAir, dust & atmospheric transportPMC5264584 , PMC9082502
CEDs02596Ambient AirAir, dust & atmospheric transportPMC6612795 , PMC8237064
CEDs02597StratosphereAir, dust & atmospheric transportPMC4374930 , PMC12500755
CEDs02600SnowAir, dust & atmospheric transportPMC8282802
CEDs02603AtmosphericAir, dust & atmospheric transportPMC10030638 , PMC11324526
CEDs02606Air PollutionAir, dust & atmospheric transportPMC12753933 , PMC12753933
CEDs02607Polluted AirAir, dust & atmospheric transportPMC7035480
CEDs02613TroposphereAir, dust & atmospheric transportPMC7894209 , PMC7894209
CEDs02616TroposphericAir, dust & atmospheric transportPMC4374930 , PMC4374930
CEDs02617Free TroposphereAir, dust & atmospheric transportPMC7894209 , PMC7894209
CEDs02618Lower StratosphereAir, dust & atmospheric transportPMC6853249 , PMC6853249
CEDs02621Ambient Air PollutionAir, dust & atmospheric transportPMC12024188 , PMC11432464
CEDs02639Dry AirAir, dust & atmospheric transportPMC4744722
CEDs02652StratosphericAir, dust & atmospheric transportPMC4374930
CEDs02658Atmospheric Boundary LayerAir, dust & atmospheric transportPMC10820161
CEDs02676Workplace AirAir, dust & atmospheric transportPMC10964904
CEDs02678Air AtmosphereAir, dust & atmospheric transportPMC6427108
CEDs02681Secondary AerosolAir, dust & atmospheric transportPMC4191923
CEDs02703Marine AtmosphereAir, dust & atmospheric transportPMC10909991
CEDs02748Building MaterialsBuilding & ConstructionPMC8384485
CEDs02771Asphalt PavementBuilding & ConstructionPMC12113609
CEDs02932KitchenHousehold itemsPMC9402372
CEDs02954Fossil FuelsEnergy, oil & gasPMC9791684 , PMC12500755
CEDs02955DieselEnergy, oil & gasPMC10700620
CEDs02956CoalEnergy, oil & gasPMC8475335 , PMC10700620
CEDs02964Fuel OilEnergy, oil & gasPMC10700620
CEDs02973Fossil FuelEnergy, oil & gasPMC7430176 , PMC4374930
CEDs02983BiofuelEnergy, oil & gasPMC12488026
CEDs02986Power PlantEnergy, oil & gasPMC3673189
CEDs03009Waste WaterWastewater, sanitation & biosolidsPMC10053030 , PMC12089771
CEDs03014SewageWastewater, sanitation & biosolidsPMC4374930
CEDs03021Wastewater Treatment PlantWastewater, sanitation & biosolidsPMC4374930 , PMC8807015
CEDs03043WWTPsWastewater, sanitation & biosolidsPMC12089771 , PMC10716752
CEDs03072Urban WastewaterWastewater, sanitation & biosolidsPMC4374930 , PMC4374930
CEDs03217FurnishingsTextiles, leather & furnishingsPMC8384485
CEDs03273Exhaust GasAutomotive & urban infrastructurePMC8696848 , PMC10663487
CEDs03275Exhaust GasesAutomotive & urban infrastructurePMC9362473 , PMC9814107
CEDs03281Vehicle ExhaustAutomotive & urban infrastructurePMC6950242 , PMC12800077
CEDs03285Exhaust EmissionsAutomotive & urban infrastructurePMC9067409
CEDs03290Urban EnvironmentsAutomotive & urban infrastructurePMC7831994
CEDs03297ExhaustAutomotive & urban infrastructurePMC9067409
CEDs03302Urban AreasAutomotive & urban infrastructurePMC12944996
CEDs03304Automotive ExhaustAutomotive & urban infrastructurePMC6068494
CEDs03305Traffic EmissionsAutomotive & urban infrastructurePMC13211739
CEDs03306Motor VehicleAutomotive & urban infrastructurePMC3673189
Pathways
1 pathwayPathway Source: PathBank
Targets
StructureProteinUniProt IDOrganismRelationshipDetails
Flavohemoprotein structureClick to view 3D structureFlavohemoproteinP24232Escherichia coli (strain K12)KnownNot Available
Carbonic anhydrase 1 structureClick to view 3D structureCarbonic anhydrase 1P00915HumansPredicted (SEA)
Prediction Confidence Score
0.076
Applicability Domain
0.1 Low confidence
Statistical Significance
1.0
Supporting Reference Compounds
407
E-value
7784.84
Carbonic anhydrase 9 structureClick to view 3D structureCarbonic anhydrase 9Q16790HumansPredicted (SEA)
Prediction Confidence Score
0.067
Applicability Domain
0.1 Low confidence
Statistical Significance
1.0
Supporting Reference Compounds
372
E-value
7784.84
Acetylcholinesterase structureClick to view 3D structureAcetylcholinesteraseP07140Drosophila melanogasterPredicted (SEA)
Prediction Confidence Score
0.064
Applicability Domain
0.08 Low confidence
Statistical Significance
0.6596
Supporting Reference Compounds
2
E-value
5135.25
Click to view 3D structureHistidine biosynthesis bifunctional protein HisBP06987Escherichia coli O26:H11 str. CFSAN001629Predicted (SEA)
Prediction Confidence Score
0.059
Applicability Domain
0.059 Low confidence
Statistical Significance
0.7791
Supporting Reference Compounds
1
E-value
6065.39
Carbonic anhydrase 2 structureClick to view 3D structureCarbonic anhydrase 2P00918HumansPredicted (SEA)
Prediction Confidence Score
0.056
Applicability Domain
0.071 Low confidence
Statistical Significance
1.0
Supporting Reference Compounds
472
E-value
7784.77
Click to view 3D structureCarbonic anhydrase 5B, mitochondrialQ9Y2D0HumansPredicted (SEA)
Prediction Confidence Score
0.055
Applicability Domain
0.071 Low confidence
Statistical Significance
0.9999
Supporting Reference Compounds
157
E-value
7784.53
Click to view 3D structureCarbonic anhydrase 5A, mitochondrialP35218HumansPredicted (SEA)
Prediction Confidence Score
0.054
Applicability Domain
0.071 Low confidence
Statistical Significance
1.0
Supporting Reference Compounds
165
E-value
7784.61
Click to view 3D structureRas-related C3 botulinum toxin substrate 1P63001Mus musculusPredicted (SEA)
Prediction Confidence Score
0.053
Applicability Domain
0.053 Low confidence
Statistical Significance
0.9681
Supporting Reference Compounds
1
E-value
7536.89
Replicase polyprotein 1ab structureClick to view 3D structureReplicase polyprotein 1abP0DTD1SARS-CoV-2Predicted (SEA)
Prediction Confidence Score
0.051
Applicability Domain
0.067 Low confidence
Statistical Significance
1.0
Supporting Reference Compounds
215
E-value
7784.69
Click to view 3D structureCarbonic anhydrase 13Q9D6N1Mus musculusPredicted (SEA)
Prediction Confidence Score
0.05
Applicability Domain
0.091 Low confidence
Statistical Significance
0.9999
Supporting Reference Compounds
70
E-value
7784.46
Carbonic anhydrase 7 structureClick to view 3D structureCarbonic anhydrase 7P43166HumansPredicted (SEA)
Prediction Confidence Score
0.049
Applicability Domain
0.071 Low confidence
Statistical Significance
1.0
Supporting Reference Compounds
242
E-value
7784.61
Carbonic anhydrase 4 structureClick to view 3D structureCarbonic anhydrase 4P22748HumansPredicted (SEA)
Prediction Confidence Score
0.049
Applicability Domain
0.071 Low confidence
Statistical Significance
1.0
Supporting Reference Compounds
193
E-value
7784.69
Replicase polyprotein 1ab structureClick to view 3D structureReplicase polyprotein 1abK9N7C7Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012)Predicted (SEA)
Prediction Confidence Score
0.049
Applicability Domain
0.067 Low confidence
Statistical Significance
1.0
Supporting Reference Compounds
48
E-value
7784.61
Click to view 3D structureMitogen-activated protein kinase 2O42781Pneumocystis cariniiPredicted (SEA)
Prediction Confidence Score
0.045
Applicability Domain
0.045 Low confidence
Statistical Significance
0.9302
Supporting Reference Compounds
1
E-value
7241.77
Carbonic anhydrase 12 structureClick to view 3D structureCarbonic anhydrase 12O43570HumansPredicted (SEA)
Prediction Confidence Score
0.045
Applicability Domain
0.048 Low confidence
Statistical Significance
1.0
Supporting Reference Compounds
332
E-value
7784.69
Click to view 3D structureProstaglandin-H2 D-isomeraseO02853Bos taurusPredicted (SEA)
Prediction Confidence Score
0.044
Applicability Domain
0.044 Low confidence
Statistical Significance
0.9742
Supporting Reference Compounds
1
E-value
7584.23
Click to view 3D structureBeta-lactamase OXA-2P0A1V9Escherichia coliPredicted (SEA)
Prediction Confidence Score
0.044
Applicability Domain
0.044 Low confidence
Statistical Significance
0.924
Supporting Reference Compounds
1
E-value
7193.03
Click to view 3D structureBeta-lactamase pse-1Q2V0Y6Escherichia coliPredicted (SEA)
Prediction Confidence Score
0.044
Applicability Domain
0.044 Low confidence
Statistical Significance
0.924
Supporting Reference Compounds
1
E-value
7193.03
D(3) dopamine receptor structureClick to view 3D structureD(3) dopamine receptorP35462HumansPredicted (SEA)
Prediction Confidence Score
0.044
Applicability Domain
0.061 Low confidence
Statistical Significance
1.0
Supporting Reference Compounds
861
E-value
7784.69
Carbonic anhydrase structureClick to view 3D structureCarbonic anhydraseQ5AJ71Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)Predicted (SEA)
Prediction Confidence Score
0.044
Applicability Domain
0.047 Low confidence
Statistical Significance
1.0
Supporting Reference Compounds
68
E-value
7784.61
Endolysin structureClick to view 3D structureEndolysinP00720Enterobacteria phage T4Predicted (SEA)
Prediction Confidence Score
0.043
Applicability Domain
0.043 Low confidence
Statistical Significance
0.9418
Supporting Reference Compounds
1
E-value
7332.15
Toll-like receptor 9 structureClick to view 3D structureToll-like receptor 9Q9NR96HumansPredicted (SEA)
Prediction Confidence Score
0.043
Applicability Domain
0.048 Low confidence
Statistical Significance
1.0
Supporting Reference Compounds
111
E-value
7784.69
Click to view 3D structureCarbonic anhydraseQ6FTL6Candida glabrata CBS 138Predicted (SEA)
Prediction Confidence Score
0.043
Applicability Domain
0.047 Low confidence
Statistical Significance
1.0
Supporting Reference Compounds
46
E-value
7784.61
Vascular endothelial growth factor receptor 2 structureClick to view 3D structureVascular endothelial growth factor receptor 2P35968HumansPredicted (SEA)
Prediction Confidence Score
0.042
Applicability Domain
0.053 Low confidence
Statistical Significance
1.0
Supporting Reference Compounds
1660
E-value
7784.69
Induced myeloid leukemia cell differentiation protein Mcl-1 structureClick to view 3D structureInduced myeloid leukemia cell differentiation protein Mcl-1Q07820HumansPredicted (SEA)
Prediction Confidence Score
0.042
Applicability Domain
0.067 Low confidence
Statistical Significance
1.0
Supporting Reference Compounds
343
E-value
7784.69
Methionine synthase structureClick to view 3D structureMethionine synthaseP13009Escherichia coli (strain K12)KnownNot Available
Nitrous-oxide reductase structureClick to view 3D structureNitrous-oxide reductaseQ51705Paracoccus denitrificansKnownNot Available
Concentrations
Not Available
External Links
DrugBank IDDB06690
HMDB IDHMDB0035807
FooDB IDFDB014561
Phenol Explorer IDNot Available
KNApSAcK IDNot Available
BiGG IDNot Available
BioCyc IDNot Available
METLIN IDNot Available
PDB IDNot Available
Wikipedia LinkNitrous_oxide
Chemspider ID923
ChEBI ID17045
PubChem Compound ID948
Kegg Compound IDC00887
YMDB IDNot Available
ECMDB IDECMDB21255
References
Synthesis ReferenceNot Available
MSDSNot Available
General References
  1. Landauer B: [Anesthesia for ambulatory patients]. Fortschr Med. 1975 Nov 13;93(32):1573-80. [PubMed: 1220997]
  2. Niijima K, Seto A, Uehara H, Takenaka I, Kadoya T: [Anesthetic management for an adult patient with secundum atrial septal defect associated with a large left-to-right shunt]. Masui. 2000 Jun;49(6):646-8. [PubMed: 10885245]
  3. Erhardt W: [Anesthesia procedures in the rabbit]. Tierarztl Prax. 1984;12(3):391-402. [PubMed: 6388029]
  4. LICHTENSTEIN ME, METHOD H: Edmund Andrews, M.D., a biographical sketch with historical notes concerning nitrousoxide oxygen anesthesia. Q Bull Northwest Univ Med Sch. 1953;27(4):337-52. [PubMed: 13112367]
  5. Makkes PC, Jonker MJ, Turk T: [Nitrous-oxide sedation indispensable in the dental care of anxious people and the mentally impaired]. Ned Tijdschr Geneeskd. 2006 May 13;150(19):1055-8. [PubMed: 16733980]
  6. Lanz E, Zimmerschitt W: [Volume and pressure changes due to nitrousoxide diffusion in costumary and in low-pressure cuffs of endotracheal tubes (author's transl)]. Anaesthesist. 1976 Oct;25(10):491-8. [PubMed: 984380]
  7. Yannai, Shmuel. (2004) Dictionary of food compounds with CD-ROM: Additives, flavors, and ingredients. Boca Raton: Chapman & Hall/CRC.