Quercetin (CED0000907)

Record Information
Version1.0
Creation Date2014-09-11 05:15:10 UTC
Update Date2026-05-14 18:06:22 UTC
SynCED IDCED0000907
Secondary Accession Numbers
  • CHEM003715
  • T3D4758
Identification
Common NameQuercetin
ClassSmall Molecule
Description
Quercetin belongs to the flavones, a subclass of flavonoids within the organic compounds. It is an exogenous solid with the formula C15H10O7 and an average molecular weight of 302.24 g/mol. It is classified under the superclass of phenylpropanoids and polyketides. The compound serves several biological and industrial roles, acting as an antioxidant (PMC9618381 ), a polyphenol (PMC8615418 , PMC11480432 ), and a reducing agent (PMC11910587 , PMC12749255 ). Industrially, it is used as a stabilizer (PMC9918917 ) and a softener and conditioner. Biologically, it functions as a drug (PMC5096843 , PMC8997561 ), an inhibitor (PMC8997561 ), an agonist (PMC3515069 ), a chelator (PMC8382892 ), an iron chelator (PMC3998679 ), an electron donor (PMC6192653 ), and a protective agent (PMC6192653 ). It targets 34 proteins, including the Estrogen receptor beta (ESR2), Adenosine receptor A2a (ADORA2A), Tyrosine-protein kinase HCK, and Glycogen synthase kinase-3 beta (GSK3B), which it can activate or inhibit. Quercetin has therapeutic effects on blood pressure (PMC13406943 ), hemolysis (PMC4966721 ), atherosclerosis (PMC6515478 ), seizure (PMC10831359 ), anxiety (PMC10831359 ), cognitive impairment (PMC11478989 ), neurodegenerative disease (PMC10135842 , PMC6269759 ), glioblastoma (PMC12466395 ), breast cancer (PMC3533855 ), and cancer (PMC10671087 , PMC11910587 ), as well as inflammation (PMC10386393 , PMC10493311 ). It is used as a treatment for COVID-19 (PMC7833388 ), hypertension (PMC12693749 ), male infertility (PMC9996255 ), cervical cancer (PMC7698010 ), atherosclerosis (PMC8253632 ), breast cancer (PMC12021792 ), and cognitive impairment (PMC12709879 ). Additionally, it is associated with weight gain, diarrhea, and gastroesophageal reflux disease (PMC12008688 ), renal cell carcinoma (PMC6331815 ), and inflammation (PMC10812391 ), while showing an inverse association with squamous cell carcinoma and lung cancer (PMC5000748 ). Exposure may occur via inhalation, oral, or touch routes across sectors including medical devices, synthetic textiles, and electronic equipment.
Contaminant Type
  • Antioxidant
  • Ester
  • Food Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
  • PFAS
  • Phytotoxin
  • Plant Toxin
Chemical Structure
Synonyms
ValueSource
2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-oneChEBI
3,3',4',5,7-PentahydroxyflavoneChEBI
3,5,7,3',4'-PentahydroxyflavoneChEBI
SophoretinChEBI
XanthaurineChEBI
3,3',4,5,7-PentahydroxyflavoneKegg
DikvertinMeSH
2-(3,4-Dihydroxy-phenyl)-3,5,7-trihydroxy-chromen-4-oneHMDB
3',4',5,7-Tetrahydroxyflavan-3-olHMDB
3',4',5,7-Tetrahydroxyflavon-3-olHMDB
3,4',5,5',7-Pentahydroxy-flavoneHMDB
3,5,7-Trihydroxy-2-(3,4-dihydroxyphenyl)-4H-chromen-4-ONHMDB
Flavin meletinHMDB
MeletinHMDB
Quercetin dihydrateHMDB
QuercetolHMDB
QuertinHMDB
2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-benzopyran-4-onePhytoBank
3,3’,4’,5,7-PentahydroxyflavonePhytoBank
3,5,7,3’,4’-PentahydroxyflavonePhytoBank
3,5,7-Trihydroxy-2-(3,4-dihydroxyphenyl)-4H-chromen-4-onePhytoBank
3'-HydroxykaempferolPhytoBank
3’-HydroxykaempferolPhytoBank
QuercetinePhytoBank
QuertinePhytoBank
Chemical FormulaC15H10O7
Average Molecular Mass302.236 g/mol
Monoisotopic Mass302.043 g/mol
CAS Registry Number117-39-5
IUPAC Name2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-one
Traditional Namequercetin
SMILESOC1=CC2=C(C(O)=C1)C(=O)C(O)=C(O2)C1=CC=C(O)C(O)=C1
InChI IdentifierInChI=1S/C15H10O7/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6/h1-5,16-19,21H
InChI KeyREFJWTPEDVJJIY-UHFFFAOYSA-N
Chemical Taxonomy
Description Belongs to the class of organic compounds known as flavonols. Flavonols are compounds that contain a flavone (2-phenyl-1-benzopyran-4-one) backbone carrying a hydroxyl group at the 3-position.
KingdomOrganic compounds
Super ClassPhenylpropanoids and polyketides
ClassFlavonoids
Sub ClassFlavones
Direct ParentFlavonols
Alternative Parents
Substituents
  • 3-hydroxyflavone
  • 3'-hydroxyflavonoid
  • 3-hydroxyflavonoid
  • 4'-hydroxyflavonoid
  • 5-hydroxyflavonoid
  • 7-hydroxyflavonoid
  • Hydroxyflavonoid
  • Chromone
  • Benzopyran
  • 1-benzopyran
  • Catechol
  • 1-hydroxy-4-unsubstituted benzenoid
  • 1-hydroxy-2-unsubstituted benzenoid
  • Phenol
  • Pyranone
  • Benzenoid
  • Monocyclic benzene moiety
  • Pyran
  • Heteroaromatic compound
  • Vinylogous acid
  • Oxacycle
  • Organoheterocyclic compound
  • Polyol
  • Organic oxide
  • Organic oxygen compound
  • Hydrocarbon derivative
  • Organooxygen compound
  • Aromatic heteropolycyclic compound
Molecular FrameworkAromatic heteropolycyclic compounds
External Descriptors
Biological Properties
StatusDetected and Not Quantified
OriginExogenous
Cellular Locations
  • Membrane
Biofluid LocationsNot Available
Tissue LocationsNot Available
ApplicationsNot Available
Biological Roles
Chemical RolesNot Available
Organoleptic Effects
  • yellow colour ?
  • red colour ?
  • yellow-orange colour ?
  • bitter taste ?
  • brown colour ?
  • dark brown colour ?
  • yellowish colour ?
  • coarse touch ?
  • yellowish green colour ?
Physical Properties
StateSolid
AppearanceWhite powder.
Experimental Properties
PropertyValue
Melting Point316.5°C
Boiling PointNot Available
Solubility60 mg/L (at 16°C)
Predicted Properties
PropertyValueSource
Water Solubility0.26 g/LALOGPS
logP1.81ALOGPS
logP2.16ChemAxon
logS-3.1ALOGPS
pKa (Strongest Acidic)6.38ChemAxon
pKa (Strongest Basic)-4ChemAxon
Physiological Charge-1ChemAxon
Hydrogen Acceptor Count7ChemAxon
Hydrogen Donor Count5ChemAxon
Polar Surface Area127.45 ŲChemAxon
Rotatable Bond Count1ChemAxon
Refractivity76.86 m³·mol⁻¹ChemAxon
Polarizability28.54 ųChemAxon
Number of Rings3ChemAxon
BioavailabilityYesChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon
Spectra
Spectra
Spectrum TypeDescriptionSplash KeyDeposition DateView
GC-MSGC-MS Spectrumsplash10-0bt9-2611390000-f8e98c928a7ed82acda4Not AvailableView Spectrum
GC-MSGC-MS Spectrumsplash10-0bt9-2611390000-f8e98c928a7ed82acda4Not AvailableView Spectrum
Predicted GC-MSPredicted GC-MS Spectrumsplash10-0079-0591000000-2a146657da898ec9322eNot AvailableView Spectrum
Predicted GC-MSPredicted GC-MS Spectrumsplash10-00l2-2093078000-1de46637305246feffd2Not AvailableView Spectrum
Predicted GC-MSPredicted GC-MS SpectrumNot AvailableNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0009000000-d4689b76f41c73487399Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0967000000-613e61ec0c69ed0ee630Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0uy0-5910000000-ee816015eec26c8621b1Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0009000000-ec1cab852ed9f9f78fa4Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-1907000000-6f36df2733dadae380c2Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0309000000-976a99c106ceca16d73bNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0pi0-1900000000-b2e286366d41e47dd8fcNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0209000000-e891863ec110aeb660b0Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0940000000-aa52db00c1defe3ccf75Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0219000000-5ef285c4b6bfd220b8b1Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0219000000-547c83bb70e7da007d6cNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-1907000000-a59602c09f66e9656068Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0009000000-4416f39adf6c9b919bfaNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0019000000-eb14ec62fc2fb2f1da88Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0ufr-0910000000-0730bca525c17aac75c5Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-004i-0030290000-06238e4a98a4daad3265Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0039008002-9df3edfb34deb15f8474Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0039008002-9df3edfb34deb15f8474Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0uka-0193000000-3325ca1a080730a9c0bfNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-00di-0690000000-fc73e696aa7dda4ed068Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-00di-0690000000-fc73e696aa7dda4ed068Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-00di-0690000000-fc73e696aa7dda4ed068Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-00di-0690000000-fc73e696aa7dda4ed068Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-00di-0690000000-fc73e696aa7dda4ed068Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-00di-0690000000-fc73e696aa7dda4ed068Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0kmi-0920000000-2cd49ad40f2f08fee3abNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-00di-0090000000-6e7d9bd766aeac1e8423Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0039008002-9df3edfb34deb15f8474Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0f6t-0095000000-263e67f066235717bcedNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0uka-0193000000-3325ca1a080730a9c0bfNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-00di-0690000000-fc73e696aa7dda4ed068Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0uk9-0930000000-363b1bf4e9a6499fb535Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-014i-0900000000-845f3e731d2cccac16f9Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-014i-0900000000-9b75e80bd57dc444dda7Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-014i-0900000000-3d57664b65937f1fdbe8Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udj-0059000000-4569f9771af75819d4ffNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0f6t-0096000000-8e3b5b434e0a7ac4a6f2Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0kmi-0920000000-2cd49ad40f2f08fee3abNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0009000000-72d3757130f6362ef16dNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0409000000-a4dcf8e7bf7fc06c6095Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0911000000-26d2681925e713dea7c4Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0uk9-0900000000-5be8620fbd47ec2d1052Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0fk9-0900000000-8ac4420cd3971f9601a6Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0009000000-fb7dfb09272d435ea607Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0903000000-fd4be6f2614be7172a35Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0zmi-1900000000-9b0554a80fe8e8b94408Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0829-8900000000-d5a528d6e21b618ea2b1Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0915000000-7a3fb3aa5f4be69956d8Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0910000000-350f78e2382f3fecc61aNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0910000000-ddd05c50a7b3c03051a4Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-1907000000-5aa9a239adad90fab984Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0309000000-976a99c106ceca16d73bNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0pi0-1900000000-272962af7f0845810af5Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0209000000-e891863ec110aeb660b0Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-1907000000-a59602c09f66e9656068Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0ufr-0910000000-0730bca525c17aac75c5Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0912000000-7266f09b33299900ac8eNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0109000000-b493a0a82085432cebf6Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0019000000-c0d60f99f3eee7a22cd0Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-1149000000-3599b5960dcb4fc954ceNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0924000000-366e21015025ab5b67e3Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0ufr-0924000000-fc5bd30ed53f393e6bc1Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0fb9-0923000000-fe0fe51fc455246b02f1Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0ufr-0924000000-7ce36c0fa7ed55a80faaNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0fb9-0920000000-924a81fa0a3ac1416373Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0fb9-0920000000-5e828a169697753324edNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0009000000-4250e78673758d7495f7Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0009000000-c01afcb240931742dcf0Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-00di-0090000000-6e7d9bd766aeac1e8423Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0uka-0193000000-3325ca1a080730a9c0bfNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-00di-0690000000-fc73e696aa7dda4ed068Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0uk9-0930000000-363b1bf4e9a6499fb535Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-014i-0900000000-845f3e731d2cccac16f9Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-014i-0900000000-9b75e80bd57dc444dda7Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-014i-0900000000-3d57664b65937f1fdbe8Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udj-0059000000-4569f9771af75819d4ffNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0kmi-0920000000-2cd49ad40f2f08fee3abNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0009000000-928c8675170aaec9b91bNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0009000000-d6fa322373b1a4fa5481Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0119000000-240815bff9a5d73c6d37Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0972000000-4c22f12734e1fc833e7aNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0930000000-fc811aa14c3f21dd2d87Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0009000000-8653f7bcf5d38cee7445Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0009000000-f3f724fc952cbc28c800Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0ufr-0961000000-fb42c6414c6952f1e4b0Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0zi0-1910000000-86be3c6959d182874340Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0459000000-0d9988aa4ad6d4f3877fNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0972000000-03a26fc17df5ae92e2bcNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0ug0-0940000000-eab382a0773efbd9b2feNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0009000000-05f27218845a61a2bfe0Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0009000000-6db00d86c62d1532dd1fNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0029000000-1e32d3a4d88d86d283a2Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0229000000-c4a54f710dfb4852d57dNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0139000000-4ec0ac744a93b064c5d4Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0397000000-617019adfc8fd573e507Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0zi0-0393000000-acd8c0ff694dd2729721Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0940000000-08108f5a3b41c8cbfaa4Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0319000000-5ef285c4b6bfd220b8b1Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0219000000-547c83bb70e7da007d6cNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0ar9-0490000000-0d329f4c9007747360e0Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0ar9-0390000000-0c50e68e5a690203126bNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0as0-0390000000-6f746310e7a6571c58e5Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0009000000-73921279033638fe4d62Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0zg0-0393000000-c537b515119597ee9ce8Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-102i-0392000000-fc41fbc6d925de8102d1Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0as0-0290000000-4158af53d0ebb09e774fNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0ar9-0390000000-161921c02329eabfc797Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0bw9-0490000000-e5bf1722511e153aff65Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0bvr-0390000000-197d114a9278c0e2612aNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-00di-0069000000-6dd55093362f957e659eNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-00di-0069000000-b8c19af3c8a71771daf8Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0032-0001972000-01954ed9f56878d69e84Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0095-0002972000-7e43cd97850471788609Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0006-0009000000-d5a15ff9735e3c526282Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0006-0009000000-de714935daaf0eeba0ceNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0a4i-0390000000-87d30204432f9e209880Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0a6r-0390000000-5fe461c56b458083044fNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0129000000-7ce37e7933aa2c84cd6fNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0639000000-c7898f09f3583402c20cNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0a4i-0190000000-b6ecf156f50465603115Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0ar9-0390000000-1d9c9c7e160b0ef3b8caNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-056r-1900000000-b18ca51d0c809a244aa2Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0009000000-6ef0af3bd95b5a7034d8Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0009000000-980489cf8c266fb25034Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0961000000-87354522d30333a1714aNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0916000000-00830a80eaf36eeaed30Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0zmi-1910000000-3d33ea1d2c26c23b3235Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0029000000-2daaf63d538cf1985d9eNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0829-8900000000-d5a528d6e21b618ea2b1Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0zmi-1900000000-9b0554a80fe8e8b94408Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0009000000-82418d56a4182176a4f0Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0ufr-0951000000-65afbd13d66587b47326Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0109000000-69a999c383a9b200efcfNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0109000000-3946b78bf4a045cc81b6Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0009000000-af736fdeea5bc2e5e1c5Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0ufr-1592000000-4436fe1f52291cf8ed40Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0119000000-9378ea84ebdfa61de02dNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0009000000-4c26219d2d2f589ae910Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0009000000-4018f91a3272eb878481Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0zfr-1910000000-02c5fa55809ddb7d922dNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0916000000-00c3051ee25f48d3ed1dNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0961000000-a68a5a040816a09d7b9eNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0009000000-18d9feff293d5ced9171Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0119000000-2acbdcf7021ab78414ddNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-014i-9200000000-4d4fc1b7d5f26e6c8175Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0002-0890000000-76e75e7eaa08ad86a0f1Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0829-9800000000-7cdb4f81e1ed30580027Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0901000000-e27fbb889defc6f3246dNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-02t9-9500000000-76153dac3585a3a1a3ddNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-00di-0090000000-6e7d9bd766aeac1e8423Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0903000000-d68267b909112df72203Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0zi0-1910000000-a33ba8302f62dd20fe14Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0ufr-1592000000-0ce06a588d0fd1b11a41Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-014i-0900000000-845f3e731d2cccac16f9Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-00di-0690000000-fc73e696aa7dda4ed068Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0q29-5900000000-580a8066a6b08cec8446Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0409000000-7f8158b0d2538229fda0Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-1900000000-c9041b25e9801730a899Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udj-0059000000-4569f9771af75819d4ffNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0109000000-0c37266f656150ddda33Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0009000000-cc7fdeca5e77ae091a66Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0916000000-6e2117fce0fe33324745Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0109000000-01b990a31a6da92e670fNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0uk9-0930000000-363b1bf4e9a6499fb535Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-014i-0900000000-3d57664b65937f1fdbe8Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0903000000-05fe7a0198cfac0a9f91Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0209000000-c025cd96d950ee42cf7aNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0zi0-1910000000-31620106f89791b72329Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0912000000-7266f09b33299900ac8eNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0139000000-0cb3e6739eb705e820caNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0009000000-8653f7bcf5d38cee7445Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0zmi-1910000000-3f639b8c671b47811a21Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0zmi-1910000000-b674f7bbd1c9488aa378Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-014i-0900000000-9b75e80bd57dc444dda7Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0829-8900000000-55b7b2d2335f25fb7d0fNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0930000000-db4615c8318a76fb7a43Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0kmi-0920000000-2cd49ad40f2f08fee3abNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-05nf-6900000000-24b3b542a436f55a0c30Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0916000000-5006647ff020a895364eNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0930000000-fc811aa14c3f21dd2d87Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0397000000-886355f8519fd07f19deNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0009000000-f3f724fc952cbc28c800Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0109000000-27f857d6e279867eec0fNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0aor-2900000000-95544cf74d4226bbc783Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0fk9-0900000000-881c1412acf0164ade76Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0972000000-e5df659a5d7a43e7b18dNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0019000000-395be4e4647bf7e7baabNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0109000000-1bac87cd7b28fd5e74f0Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0927000000-bb9c127128546695da45Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0ufr-0961000000-138f143d62174882ddf9Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0zi0-0394000000-d6d72cba82f72a7a70b5Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0972000000-4c22f12734e1fc833e7aNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0916000000-da32954fc03a3807d6e1Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0fbc-0910000000-c653f2499fe45d875428Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0zmi-1900000000-9eb939d953ce79c00ec5Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0uk9-0900000000-c8cb569d79c85488afdbNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0uka-0193000000-3325ca1a080730a9c0bfNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-00gi-0900000000-528774d0f56ab8576300Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0209000000-5775cc0c20c91fabcc49Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0119000000-240815bff9a5d73c6d37Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0229000000-d20bb53f32485977f34bNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0009000000-928c8675170aaec9b91bNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0002-0890000000-fb0f8c4842a1426078b9Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-01c3-4900000000-9b24c84af65520012497Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0009000000-1817ec89cbb53d14e565Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0009000000-50cb12ee63eb836e6e9eNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0zfr-1910000000-49093a1c8d93be76ab5dNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0002-0490000000-23e4cd24aa0b50828a85Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0009000000-d6fa322373b1a4fa5481Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0zi0-1910000000-86be3c6959d182874340Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0911000000-26d2681925e713dea7c4Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0409000000-a4dcf8e7bf7fc06c6095Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-056r-2900000000-8d3319ba951d94cd8724Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0zmi-1910000000-f6fa26b28b0ec52c12e5Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0ufr-0960000000-e1712df55aaba6b62771Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0ufr-0961000000-9eb33346a7c755c7603bNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-1930000000-7d7b15f99f750f7f543aNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0009000000-cfbdeb49c0cd96b42340Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-056r-1900000000-19105141f6c2495b3295Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0109000000-6082916b9bcbb299507aNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0ufr-0951000000-c042bfa3675698a6bf3fNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0009000000-72d3757130f6362ef16dNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0009000000-993f0ec194dea4f966a3Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0927000000-4baa8f8da7e0be84fd35Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0209000000-f241e1f38cf7f1456ac9Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0fk9-0900000000-8ac4420cd3971f9601a6Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0ufr-0960000000-48ff858d3aa237d0798bNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0009000000-e70941f03a1f7058c402Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0uk9-0900000000-5be8620fbd47ec2d1052Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0q29-5900000000-346c54c0770b448cc127Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0kdi-1910000000-e47c9bbf08e26da8abdcNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0009000000-fb7dfb09272d435ea607Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0903000000-fd4be6f2614be7172a35Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0109000000-61f30592a9a57e75303fNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-02t9-9500000000-e55d54c2a97123ed0f26Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-0udi-0019000000-ee8570ac70818e8939bbNot AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-0udi-0279000000-71b5db7ef8322cc8b9e9Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-0zg0-7960000000-7edbb229853a642749acNot AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-0udi-0009000000-21580b9d8394d2eea3a5Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-0udi-0239000000-b77fcb9c0ce11dc515bfNot AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-0apr-5940000000-0590bdee504c5ed6ba36Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-0udi-0009000000-ee351f9e9fc725a3bf83Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-0udi-0619000000-c882e3e9fb5c0d5daab2Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-0zg0-1930000000-00e911ff7f9335cd0835Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-0udi-0009000000-83a0d85bdd6b793b4e43Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-0udi-0009000000-b2f55ae4e63b415a0950Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-0udi-1912000000-e9d3cb901e6e40959d88Not AvailableView Spectrum
1D NMR1H NMR Spectrum (1D, DMSO, experimental)Not AvailableNot AvailableView Spectrum
Toxicity Profile
Toxicity Values
Toxicity ValueOrganismDose DescriptorRoute of ExposurePredicted or ExperimentalToxicity RatingReference
2798.0 Log mg/kg [1600:5000]RatLD50oralpredictedNot AvailableNot Available
20.0 mg/kg-day RatLOELoralexperimentalNot AvailableECOTOX - EPA ORD
20.0 mg/kg-day RatNOELoralexperimentalNot AvailableECOTOX - EPA ORD
20.0 mg/kg-day RatNOELoralexperimentalNot AvailableECOTOX - EPA ORD
20.0 mg/kg-day RatNOELoralexperimentalNot AvailableECOTOX - EPA ORD
Toxicity / Toxin ClassNot Available
Mechanism of ToxicityQuercetin is a specific quinone reductase 2 (QR2) inhibitor, an enzyme (along with the human QR1 homolog) which catalyzes metabolism of toxic quinolines. Inhibition of QR2 in plasmodium may potentially cause lethal oxidative stress. The inhibition of antioxidant activity in plasmodium may contribute to killing the malaria causing parasites.
Carcinogenicity (IARC Classification)3, not classifiable as to its carcinogenicity to humans. (2)
Minimum Risk LevelNot Available
SymptomsNot Available
TreatmentNot Available
Health Effects
Health EffectRelationshipDirectionDescriptionReference
lung cancerAssociated With?inverseA respiratory system cancer that is located in the lung. (DO)PMC5000748 , PMC5000748
lung cancerHas Therapeutic Effect OnNot AvailableA respiratory system cancer that is located in the lung. (DO)PMC3703873
hypertensionNot AvailableNot AvailableA disorder characterized by a pathological increase in blood pressure; a repeatedly elevation in the blood pressure exceeding 140 over 90 mm Hg. (NCI CTCAE)PMC12693749
hypertensionHas Therapeutic Effect OnNot AvailableA disorder characterized by a pathological increase in blood pressure; a repeatedly elevation in the blood pressure exceeding 140 over 90 mm Hg. (NCI CTCAE)PMC11677590 , PMC12469104
blood pressureHas Therapeutic Effect OnNot AvailableNot AvailablePMC13406943
inflammationHas Therapeutic Effect OnNot AvailableNot AvailablePMC10386393 , PMC10493311
inflammationAssociated With?Not AvailableNot AvailablePMC10812391 , PMC12343168
inflammationNot AvailableNot AvailableNot AvailablePMC10607042 , PMC10146286
cancerHas Therapeutic Effect OnNot AvailableCancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. Possible signs and symptoms include a lump, abnormal bleeding, prolonged cough, unexplained weight loss, and a change in bowel movements. There are over 100 types of cancers affect humans. The risk of developing certain cancers can be reduced by not smoking, maintaining a healthy weight, not drinking too much alcohol, eating plenty of vegetables, fruits and whole grains, vaccination against certain infectious diseases, not eating too much processed and red meat and avoiding too much sunlight exposure. Cancer is often treated with some combination of radiation therapy, surgery, chemotherapy and targeted therapy. The majority of cancers, some 90–95% of cases, are due to genetic mutations from environmental and lifestyle factors. The remaining 5–10% are due to inherited genetics.PMC10671087 , PMC11910587
cancerNot AvailableNot AvailableCancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. Possible signs and symptoms include a lump, abnormal bleeding, prolonged cough, unexplained weight loss, and a change in bowel movements. There are over 100 types of cancers affect humans. The risk of developing certain cancers can be reduced by not smoking, maintaining a healthy weight, not drinking too much alcohol, eating plenty of vegetables, fruits and whole grains, vaccination against certain infectious diseases, not eating too much processed and red meat and avoiding too much sunlight exposure. Cancer is often treated with some combination of radiation therapy, surgery, chemotherapy and targeted therapy. The majority of cancers, some 90–95% of cases, are due to genetic mutations from environmental and lifestyle factors. The remaining 5–10% are due to inherited genetics.PMC10459502 , PMC9664067
cancerAssociated With?Not AvailableCancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. Possible signs and symptoms include a lump, abnormal bleeding, prolonged cough, unexplained weight loss, and a change in bowel movements. There are over 100 types of cancers affect humans. The risk of developing certain cancers can be reduced by not smoking, maintaining a healthy weight, not drinking too much alcohol, eating plenty of vegetables, fruits and whole grains, vaccination against certain infectious diseases, not eating too much processed and red meat and avoiding too much sunlight exposure. Cancer is often treated with some combination of radiation therapy, surgery, chemotherapy and targeted therapy. The majority of cancers, some 90–95% of cases, are due to genetic mutations from environmental and lifestyle factors. The remaining 5–10% are due to inherited genetics.PMC11646371 , PMC7288015
Alzheimer's diseaseHas Therapeutic Effect OnNot AvailableA neurodegenerative disease which causes neural atrophy, leading to dementia and memory loss.PMC12192584
breast cancerNot AvailableNot AvailableA breast cancer that has material basis in abnormally proliferating cells derives from epithelial cells. (DO)PMC12021792 , PMC10546754
breast cancerHas Therapeutic Effect OnNot AvailableA breast cancer that has material basis in abnormally proliferating cells derives from epithelial cells. (DO)PMC3533855 , PMC8360750
breast cancerAssociated With?Not AvailableA breast cancer that has material basis in abnormally proliferating cells derives from epithelial cells. (DO)PMC7412346
type 2 diabetes mellitusHas Therapeutic Effect OnNot AvailableNot AvailablePMC13200494 , PMC9352109
osteoporosisNot AvailableNot AvailableA disorder characterized by reduced bone mass, with a decrease in cortical thickness and in the number and size of the trabeculae of cancellous bone (but normal chemical composition), resulting in increased fracture incidence. (NCI CTCAE)PMC5297185
fatigueHas Therapeutic Effect OnNot AvailableA disorder characterized by a state of generalized weakness with a pronounced inability to summon sufficient energy to accomplish daily activities. (NCI CTCAE)PMC10220679
asthmaNot AvailableNot AvailableA bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has symptom recurring periods of wheezing (a whistling sound while breathing), has symptom chest tightness, has symptom shortness of breath, has symptom mucus production and has symptom coughing. The symptoms appear due to a variety of triggers such as allergens, irritants, respiratory infections, weather changes, exercise, stress, reflux disease, medications, foods and emotional anxiety. (DO)PMC3269694
asthmaHas Therapeutic Effect OnNot AvailableA bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has symptom recurring periods of wheezing (a whistling sound while breathing), has symptom chest tightness, has symptom shortness of breath, has symptom mucus production and has symptom coughing. The symptoms appear due to a variety of triggers such as allergens, irritants, respiratory infections, weather changes, exercise, stress, reflux disease, medications, foods and emotional anxiety. (DO)PMC7919894 , PMC12430178
diabetes mellitusNot AvailableNot AvailableA glucose metabolism disease characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both. (DO)PMC10646315 , PMC9785621
diabetes mellitusHas Therapeutic Effect OnNot AvailableA glucose metabolism disease characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both. (DO)PMC10375682 , PMC11184148
cervical cancerNot AvailableNot AvailableA female reproductive organ cancer that is located in the cervix. (DO)PMC7698010
rheumatoid arthritisHas Therapeutic Effect OnNot AvailableAn arthritis that is an autoimmune disease which attacks healthy cells and tissue located in joint. (DO)PMC10334012
rheumatoid arthritisNot AvailableNot AvailableAn arthritis that is an autoimmune disease which attacks healthy cells and tissue located in joint. (DO)PMC10458784
diarrheaAssociated With?Not AvailableA disorder characterized by an increase in frequency and/or loose or watery bowel movements. (NCI CTCAE)PMC12008688
diarrheaHas Therapeutic Effect OnNot AvailableA disorder characterized by an increase in frequency and/or loose or watery bowel movements. (NCI CTCAE)PMC8689231
diarrheaNot AvailableNot AvailableA disorder characterized by an increase in frequency and/or loose or watery bowel movements. (NCI CTCAE)PMC8689231
neuropathic painHas Therapeutic Effect OnNot AvailableNot AvailablePMC10556381
painHas Therapeutic Effect OnNot AvailableA disorder characterized by the sensation of marked discomfort, distress or agony. (NCI CTCAE)PMC5123821
hemolysisHas Therapeutic Effect OnNot AvailableNot AvailablePMC4966721
weight gainAssociated With?Not AvailableA finding characterized by an increase in overall body weight; for pediatrics, greater than the baseline growth curve. (NCI CTCAE)PMC12008688 , PMC12008688
Prostate cancerHas Therapeutic Effect OnNot AvailableA male reproductive organ cancer that is located in the prostate. (DO)PMC3703873 , PMC3670510
Prostate cancerAssociated With?Not AvailableA male reproductive organ cancer that is located in the prostate. (DO)PMC13175067
melanomaNot AvailableNot AvailableA cell type cancer that has material basis in abnormally proliferating cells derives from melanocytes which are found in skin, the bowel and the eye. (DO)PMC12157913
melanomaHas Therapeutic Effect OnNot AvailableA cell type cancer that has material basis in abnormally proliferating cells derives from melanocytes which are found in skin, the bowel and the eye. (DO)PMC12157913 , PMC5707660
Hepatocellular carcinomaHas Therapeutic Effect OnNot AvailableA liver carcinoma that has material basis in undifferentiated hepatocytes. (DO)PMC13363538
liver cancerHas Therapeutic Effect OnNot AvailableLiver cancer, also known as hepatic cancer and primary hepatic cancer, is cancer that starts in the liver. Cancer which has spread from elsewhere to the liver, known as liver metastasis, is more common than that which starts in the liver. Symptoms of liver cancer may include a lump or pain in the right side below the rib cage, swelling of the abdomen, yellowish skin, easy bruising, weight loss and weakness.("Adult Primary Liver Cancer Treatment (PDQ®)–Patient Version". NCI. 6 July 2016. Archived from the original on 2 October 2016. Retrieved 29 September 2016) The leading cause of liver cancer is cirrhosis due to hepatitis B, hepatitis C or alcohol.(PMID: 25530442) The most common types of liver cancer are hepatocellular carcinoma (HCC), which makes up 80% of cases, and cholangiocarcinoma.(World Cancer Report 2014. World Health Organization. 2014. pp. Chapter 5.6. ISBN 978-9283204299) Globally, as of 2010, liver cancer resulted in 754,000 deaths, up from 460,000 in 1990, making it the third leading cause of cancer death after lung and stomach.(PMID: 23245604) In 2012, it represented 7% of cancer diagnoses in men, the 5th most diagnosed cancer that year.(World Cancer Report 2014. International Agency for Research on Cancer, World Health Organization. 2014. ISBN 978-92-832-0432-9)PMC3703873
colon cancerHas Therapeutic Effect OnNot AvailableNot AvailablePMC8391949
colon cancerAssociated With?Not AvailableNot AvailablePMC7412346
leukemiaAssociated With?Not AvailableA cancer that affects the blood or bone marrow characterized by an abnormal proliferation of blood cells. (DO)PMC8434187
leukemiaHas Therapeutic Effect OnNot AvailableA cancer that affects the blood or bone marrow characterized by an abnormal proliferation of blood cells. (DO)PMC5147903
anxietyHas Therapeutic Effect OnNot AvailableA disorder characterized by apprehension of danger and dread accompanied by restlessness, tension, tachycardia, and dyspnea unattached to a clearly identifiable stimulus. (NCI CTCAE)PMC10831359
obesityHas Therapeutic Effect OnNot AvailableA disorder characterized by having a high amount of body fat. (NCI CTCAE)PMC11852089 , PMC12057057
obesityNot AvailableNot AvailableA disorder characterized by having a high amount of body fat. (NCI CTCAE)PMC8689231
atherosclerosisHas Therapeutic Effect OnNot AvailableA disorder involving build-up of fatty material and calcium deposition in the arterial wall. It results in partial or complete occlusion of the arterial lumen.PMC6515478 , PMC12583478
atherosclerosisNot AvailableNot AvailableA disorder involving build-up of fatty material and calcium deposition in the arterial wall. It results in partial or complete occlusion of the arterial lumen.PMC8253632
atherosclerosisAssociated With?Not AvailableA disorder involving build-up of fatty material and calcium deposition in the arterial wall. It results in partial or complete occlusion of the arterial lumen.PMC3269694
COVID-19Not AvailableNot AvailableNot AvailablePMC7833388 , PMC7837196
COVID-19Has Therapeutic Effect OnNot AvailableNot AvailablePMC8352144 , PMC9841859
COVID-19Associated With?decreaseNot AvailablePMC10607042
COVID-19Associated With?Not AvailableNot AvailablePMC9841859
glioblastomaHas Therapeutic Effect OnNot AvailableA type of brain tumor characterized by its aggressiveness and believed to originate from astrocytes.PMC12466395 , PMC12466395
glioblastomaNot AvailableNot AvailableA type of brain tumor characterized by its aggressiveness and believed to originate from astrocytes.PMC12466395
heart failureNot AvailableNot AvailableA disorder characterized by the inability of the heart to pump blood at an adequate volume to meet tissue metabolic requirements, or, the ability to do so only at an elevation in the filling pressure. (NCI CTCAE)PMC13102569
Allergic rhinitisNot AvailableNot AvailableA rhinitis that is an allergic inflammation and irritation of the nasal airways involving sneezing, runny nose, nasal congestion, itching and tearing of the eyes caused by exposure to an allergen such as pollen, dust, mold, animal dander and droppings of cockroaches or house dust mites.PMC3269694
Allergic rhinitisHas Therapeutic Effect OnNot AvailableA rhinitis that is an allergic inflammation and irritation of the nasal airways involving sneezing, runny nose, nasal congestion, itching and tearing of the eyes caused by exposure to an allergen such as pollen, dust, mold, animal dander and droppings of cockroaches or house dust mites.PMC6630427
seizureHas Therapeutic Effect OnNot AvailableNot AvailablePMC10831359 , PMC9143627
cognitive impairmentNot AvailableNot AvailableNot AvailablePMC12709879
cognitive impairmentHas Therapeutic Effect OnNot AvailableNot AvailablePMC11478989 , PMC11722824
heart diseaseHas Therapeutic Effect OnNot AvailableA cardiovascular system disease that involves the heart. (DO)PMC10386393
pneumoniaNot AvailableNot AvailableA lung disease that involves lung parenchyma or alveolar inflammation and abnormal alveolar filling with fluid (consolidation and exudation). It results from a variety of causes including infection with bacteria, viruses, fungi or parasites, and chemical or physical injury to the lungs. It is accompanied by fever, chills, cough, and difficulty in breathing. (DO)PMC7930397 , PMC7930397
male infertilityNot AvailableNot AvailableNot AvailablePMC9996255
renal cell carcinomaAssociated With?Not AvailableA renal carcinoma that has material basis in the lining of the proximal convoluted renal tubule of the kidney. (DO)PMC6331815
ischemiaHas Therapeutic Effect OnNot AvailableA disorder characterized by a decrease or absence of blood supply to an organ or tissue, caused by obstruction (thrombosis or embolism) of an artery. (NCI CTCAE)PMC3431881 , PMC9457803
thrombosisHas Therapeutic Effect OnNot AvailableA formation of a blood clot inside a blood vessel, obstructing the flow of blood through the circulatory system.PMC6262252
ovarian cancerHas Therapeutic Effect OnNot AvailableA female reproductive organ cancer that is located in the ovary. (DO)PMC10512719 , PMC12430178
ovarian cancerAssociated With?Not AvailableA female reproductive organ cancer that is located in the ovary. (DO)PMC8434187
coronary artery diseaseAssociated With?inverseAn artery disease that is characterized by plaque building up along the inner walls of the arteries of the heart resulting in a narrowing of the arteries and a reduced blood supply to the cardiac muscles. (DO)PMC2835915
coronary artery diseaseHas Therapeutic Effect OnNot AvailableAn artery disease that is characterized by plaque building up along the inner walls of the arteries of the heart resulting in a narrowing of the arteries and a reduced blood supply to the cardiac muscles. (DO)PMC12841722 , PMC11184148
atopic dermatitisHas Therapeutic Effect OnNot AvailableNot AvailablePMC12840945
chronic inflammationHas Therapeutic Effect OnNot AvailableChronic inflammation is a slow, long-term inflammation lasting for prolonged periods of several months to years. Chronic inflammation can damage healthy cells, tissues, and organs. The main causes of the chronic inflammation includes the untreated causes of acute inflammation, such as an infection or injury, an autoimmune disorder and a long-term exposure to irritants, such as industrial chemicals or polluted air.PMC12840945
miscarriageHas Therapeutic Effect OnNot AvailableA natural death of an embryo or fetus before it is able to survive independently.PMC3966338
epilepsyHas Therapeutic Effect OnNot AvailableA brain disease that is characterized by the occurrance of at least two unprovoked seizures resulting from a persistent epileptogenic abnormality of the brain that is able to spontaneously generate paroxysmal activity and typically manifested by sudden brief episodes of altered or diminished consciousness, involuntary movements, or convulsions. (DO)PMC9143627
Parkinson's diseaseNot AvailableNot AvailableA long-term degenerative disorder of the central nervous system that mainly affects the motor system. The symptoms generally come on slowly over time.PMC6244844
Parkinson's diseaseHas Therapeutic Effect OnNot AvailableA long-term degenerative disorder of the central nervous system that mainly affects the motor system. The symptoms generally come on slowly over time.PMC12430178
pancreatic cancerHas Therapeutic Effect OnNot AvailableAn endocrine gland cancer located in the pancreas. (DO)PMC10497166
vascular diseaseHas Therapeutic Effect OnNot AvailableA cardiovascular system disease that primarily affects the blood vessels which includes the arteries, veins and capillaries that carry blood to and from the heart. (DO)PMC10375682
gastroesophageal reflux diseaseAssociated With?Not AvailableNot AvailablePMC12008688
neurodegenerative diseaseHas Therapeutic Effect OnNot AvailableA central nervous system disease that results in the progressive deterioration of function or structure of neurons. (DO)PMC10135842 , PMC6269759
neurodegenerative diseaseNot AvailableNot AvailableA central nervous system disease that results in the progressive deterioration of function or structure of neurons. (DO)PMC11722824
esophageal cancerNot AvailableNot AvailableEsophageal cancer is cancer that occurs in the esophagus — a long, hollow tube that runs from the throat to the stomach. Esophageal cancer usually begins in the cells that line the inside of the esophagus. Esophageal cancer is the sixth most common cause of cancer deaths worldwide. Incidence rates vary within different geographic locations. In some regions, higher rates of esophageal cancer may be attributed to tobacco and alcohol use or particular nutritional habits and obesity. Signs and symptoms of esophageal cancer are weight loss and painful or difficult swallowing.PMC10512719
renal fibrosisHas Therapeutic Effect OnNot AvailableNot AvailablePMC7894453
renal fibrosisNot AvailableNot AvailableNot AvailablePMC9152215
squamous cell carcinomaAssociated With?inverseA carcinoma that derives from squamous epithelial cells. (DO)PMC5000748
myopathyHas Therapeutic Effect OnNot AvailableNot AvailablePMC12572074
neurological dysfunctionHas Therapeutic Effect OnNot AvailableNot AvailablePMC13249380
allergic diseaseNot AvailableNot AvailableAllergic diseases, also known as allergies, are a number of conditions caused by hypersensitivity of the immune system to typically harmless substances in the environment. These diseases include hay fever, food allergies, atopic dermatitis, allergic asthma, and anaphylaxis. Symptoms may include red eyes, an itchy rash, sneezing, a runny nose, shortness of breath, or swelling. Common allergens include pollen and certain foods. Metals and other substances may also cause allergies. Food, insect stings, and medications are common causes of severe allergic reactions. Allergies can be due to both genetic and environmental factors. The underlying mechanism involves immunoglobulin E antibodies (IgE) binding to an allergen and then to a receptor on mast cells or basophils where it triggers the release of inflammatory chemicals such as histamine. Allergies are among the most common conditions in the world. In the developed world, about 20% of people are affected by allergic rhinitis, about 6% of people have at least one food allergy, and about 20% have atopic dermatitis at some point in time.PMC9495708
allergic diseaseHas Therapeutic Effect OnNot AvailableAllergic diseases, also known as allergies, are a number of conditions caused by hypersensitivity of the immune system to typically harmless substances in the environment. These diseases include hay fever, food allergies, atopic dermatitis, allergic asthma, and anaphylaxis. Symptoms may include red eyes, an itchy rash, sneezing, a runny nose, shortness of breath, or swelling. Common allergens include pollen and certain foods. Metals and other substances may also cause allergies. Food, insect stings, and medications are common causes of severe allergic reactions. Allergies can be due to both genetic and environmental factors. The underlying mechanism involves immunoglobulin E antibodies (IgE) binding to an allergen and then to a receptor on mast cells or basophils where it triggers the release of inflammatory chemicals such as histamine. Allergies are among the most common conditions in the world. In the developed world, about 20% of people are affected by allergic rhinitis, about 6% of people have at least one food allergy, and about 20% have atopic dermatitis at some point in time.PMC9457803
Toxic encephalopathyHas Therapeutic Effect OnNot AvailableNot AvailablePMC9423984 , PMC11722824
brain edemaHas Therapeutic Effect OnNot AvailableNot AvailablePMC3431881
colitisHas Therapeutic Effect OnNot AvailableA disorder characterized by inflammation of the colon. (NCI CTCAE)PMC10182712 , PMC10135842
sinusitisNot AvailableNot AvailableA disorder characterized by an infectious process involving the mucous membranes of the paranasal sinuses. (NCI CTCAE)PMC3269694
triple-negative breast cancerAssociated With?Not AvailableNot AvailablePMC13305355
hepatic fibrosisHas Therapeutic Effect OnNot AvailableNot AvailablePMC13200494 , PMC6192653
hepatic fibrosisNot AvailableNot AvailableNot AvailablePMC10118378
nephritisHas Therapeutic Effect OnNot AvailableA kidney disease that is characterized by an inflammation of the kidneys. (DO)PMC7894453
breast carcinomaHas Therapeutic Effect OnNot AvailableNot AvailablePMC5147903
colorectal carcinomaHas Therapeutic Effect OnNot AvailableNot AvailablePMC9657835 , PMC5147903
familial adenomatous polyposisNot AvailableNot AvailableNot AvailablePMC13164702
cleft palateHas Therapeutic Effect OnNot AvailableNot AvailablePMC9229746
viral infectious diseaseHas Therapeutic Effect OnNot AvailableNot AvailablePMC9457803
viral infectious diseaseAssociated With?Not AvailableNot AvailablePMC11646371
urinary bladder cancerHas Therapeutic Effect OnNot AvailableNot AvailablePMC9738062
Cell DeathHas Therapeutic Effect OnNot AvailableNot AvailablePMC10556381 , PMC3920909
Cell DeathAssociated With?Not AvailableNot AvailablePMC8467150
abdominal obesity-metabolic syndromeHas Therapeutic Effect OnNot AvailableNot AvailablePMC4609638
Abnormality of mitochondrial metabolismHas Therapeutic Effect OnNot AvailableNot AvailablePMC12838884 , PMC10673502
Oxidative StressHas Therapeutic Effect OnNot AvailableNot AvailablePMC12838884 , PMC12466395
Oxidative StressAssociated With?Not AvailableNot AvailablePMC10812391 , PMC12343168
Oxidative StressNot AvailableNot AvailableNot AvailablePMC9623090
injuryHas Therapeutic Effect OnNot AvailableNot AvailablePMC11786020 , PMC9618381
cardiovascular disorderHas Therapeutic Effect OnNot AvailableNot AvailablePMC13316579 , PMC11184148
cardiovascular disorderAssociated With?decreaseNot AvailablePMC6154556
cardiovascular disorderNot AvailableNot AvailableNot AvailablePMC3005390 , PMC9623090
cardiovascular disorderAssociated With?Not AvailableNot AvailablePMC12343168
Chronic DiseaseHas Therapeutic Effect OnNot AvailableNot AvailablePMC11574241
Endoplasmic Reticulum StressHas Therapeutic Effect OnNot AvailableNot AvailablePMC9143627
DNA DamageHas Therapeutic Effect OnNot AvailableNot AvailablePMC4222091 , PMC12417715
DNA DamageAssociated With?Not AvailableNot AvailablePMC3236410
FibrosisHas Therapeutic Effect OnNot AvailableNot AvailablePMC11769711
inflammatory diseaseHas Therapeutic Effect OnNot AvailableNot AvailablePMC7919894
gliomaHas Therapeutic Effect OnNot AvailableNot AvailablePMC2712839
bacterial infectious diseaseAssociated With?Not AvailableNot AvailablePMC12838092
SepsisNot AvailableNot AvailableNot AvailablePMC12156943 , PMC12406335
disease of metabolismNot AvailableNot AvailableNot AvailablePMC9785621
disease of metabolismHas Therapeutic Effect OnNot AvailableNot AvailablePMC10135842
iron poisoningHas Therapeutic Effect OnNot AvailableNot AvailablePMC4698393
nervous system disorderHas Therapeutic Effect OnNot AvailableNot AvailablePMC12192584
Lung InjuryNot AvailableNot AvailableNot AvailablePMC12406335
depressive disorderHas Therapeutic Effect OnNot AvailableNot AvailablePMC9143627 , PMC9143627
liver disorderHas Therapeutic Effect OnNot AvailableNot AvailablePMC13316579
NeoplasmsHas Therapeutic Effect OnNot AvailableNot AvailablePMC11184148
HypertrophyHas Therapeutic Effect OnNot AvailableNot AvailablePMC12880219
MorbidityAssociated With?Not AvailableNot AvailablePMC5970065
infectious diseaseNot AvailableNot AvailableNot AvailablePMC8397081
NeuroinflammationHas Therapeutic Effect OnNot AvailableNot AvailablePMC13205055 , PMC11722824
Global developmental delayHas Therapeutic Effect OnNot AvailableNot AvailablePMC3931787
AgingHas Therapeutic Effect OnNot AvailableNot AvailablePMC5872761 , PMC11184148
Cell SurvivalHas Therapeutic Effect OnNot AvailableNot AvailablePMC12215884 , PMC12215884
Cell SurvivalAssociated With?decreaseNot AvailablePMC11499993 , PMC4609638
metabolic dysfunction-associated steatotic liver diseaseNot AvailableNot AvailableNot AvailablePMC9785621
metabolic dysfunction-associated steatotic liver diseaseHas Therapeutic Effect OnNot AvailableNot AvailablePMC13171745
NeurodegenerationNot AvailableNot AvailableNot AvailablePMC9423984
NeurodegenerationHas Therapeutic Effect OnNot AvailableNot AvailablePMC4697862 , PMC9143627
NeurodegenerationAssociated With?Not AvailableNot AvailablePMC12343168
Reperfusion InjuryHas Therapeutic Effect OnNot AvailableNot AvailablePMC11184148
CardiotoxicityHas Therapeutic Effect OnNot AvailableNot AvailablePMC11677910 , PMC7579684
Mental deteriorationHas Therapeutic Effect OnNot AvailableNot AvailablePMC9826852
ischemia reperfusion injuryHas Therapeutic Effect OnNot AvailableNot AvailablePMC12880219 , PMC7331709
PruritusHas Therapeutic Effect OnNot AvailableNot AvailablePMC12873061
FrailtyAssociated With?increaseNot AvailablePMC11478989
diabetic kidney diseaseHas Therapeutic Effect OnNot AvailableNot AvailablePMC13372820 , PMC7894453
Skin AgingHas Therapeutic Effect OnNot AvailableNot AvailablePMC11783858 , PMC11783858
SARS-CoV-2Not AvailableNot AvailableNot AvailablePMC7833388
hyperlipidemiaNot AvailableNot AvailableNot AvailablePMC9785621
HypoxiaHas Therapeutic Effect OnNot AvailableNot AvailablePMC3431881
Nitrosative StressHas Therapeutic Effect OnNot AvailableNot AvailablePMC12471183
Drug Resistance, MultipleHas Therapeutic Effect OnNot AvailableNot AvailablePMC6321468
Neutrophil InfiltrationHas Therapeutic Effect OnNot AvailableNot AvailablePMC9318041
fatty liver diseaseHas Therapeutic Effect OnNot AvailableNot AvailablePMC9136617
esophagus adenocarcinomaHas Therapeutic Effect OnNot AvailableNot AvailablePMC5147903
Esophageal Squamous Cell CarcinomaHas Therapeutic Effect OnNot AvailableNot AvailablePMC3703873
hematomaHas Therapeutic Effect OnNot AvailableNot AvailablePMC9495708
congestionHas Therapeutic Effect OnNot AvailableNot AvailablePMC12880219
AllodyniaHas Therapeutic Effect OnNot AvailableNot AvailablePMC10556381
Translocation, GeneticAssociated With?Not AvailableNot AvailablePMC3998679
AtrophyHas Therapeutic Effect OnNot AvailableNot AvailablePMC12880219
cytokine release syndromeHas Therapeutic Effect OnNot AvailableNot AvailablePMC12156943
Skeletal muscle atrophyHas Therapeutic Effect OnNot AvailableNot AvailablePMC12880219 , PMC9714227
cytopeniaHas Therapeutic Effect OnNot AvailableNot AvailablePMC12008688
thyroid gland papillary carcinomaHas Therapeutic Effect OnNot AvailableNot AvailablePMC12347630
Ovarian fibrosisHas Therapeutic Effect OnNot AvailableNot AvailablePMC13200494 , PMC13200494
spinal cord injuryNot AvailableNot AvailableNot AvailablePMC9289270 , PMC12466678
spinal cord injuryHas Therapeutic Effect OnNot AvailableNot AvailablePMC4697862 , PMC12466678
bone neoplasmNot AvailableNot AvailableNot AvailablePMC12734857
Glucose Metabolism DisordersHas Therapeutic Effect OnNot AvailableNot AvailablePMC13489198
rheumatic disorderHas Therapeutic Effect OnNot AvailableNot AvailablePMC12430178
nervous system diseaseNot AvailableNot AvailableNot AvailablePMC7837196
preneoplastic lesionHas Therapeutic Effect OnNot AvailableNot AvailablePMC6192653
monosomyAssociated With?Not AvailableNot AvailablePMC3998679
trisomyAssociated With?Not AvailableNot AvailablePMC3998679
mast cell activation syndromeNot AvailableNot AvailableNot AvailablePMC9228930
Spatial MemoryHas Therapeutic Effect OnNot AvailableNot AvailablePMC11429442
Heart InjuriesHas Therapeutic Effect OnNot AvailableNot AvailablePMC8434187
Synovial lining hyperplasiaHas Therapeutic Effect OnNot AvailableNot AvailablePMC10834829
Mouth AbnormalitiesAssociated With?Not AvailableNot AvailablePMC6864204
TherapeuticsAssociated With?Not AvailableNot AvailablePMC11983675
Evoked Potentials, SomatosensoryHas Therapeutic Effect OnNot AvailableNot AvailablePMC12466678
Evoked Potentials, MotorHas Therapeutic Effect OnNot AvailableNot AvailablePMC12466678
Exposure Sources
Source IDSourceSectorReference
CEDs000007Pesticides?Pesticides are synthetic chemicals designed to prevent, destroy, or control pests that threaten crops and agricultural productivity.Agriculture & land managementNot Available
CEDs000010Insecticides?Insecticides are synthetic chemicals designed to control or eliminate insect pests that threaten crops and other agricultural products.Agriculture & land managementPubChem
CEDs000019Indoor air?Indoor air can be a significant reservoir for synthetic chemical contaminants, which often originate from various sources within enclosed environments.Air, dust & atmospheric transportNot Available
CEDs000115Drinking water?Drinking water can be a medium for synthetic chemical contamination, often originating from various industrial processes and agricultural practices.Drinking water & water supplyPMC12747205
CEDs000120Wires and cables?Wires and cables are integral components in the transmission of electrical power and signals.Electrical & Electronic EquipmentNot Available
CEDs000121Printed circuit boards?Printed circuit boards (PCBs) are essential components in the manufacturing of electronic devices, serving as the backbone for electrical connections and circuit pathways.Electrical & Electronic EquipmentNot Available
CEDs000125Batteries?Batteries are devices that store and release electrical energy through electrochemical reactions.Electrical & Electronic EquipmentNot Available
CEDs000130Semiconductors?Semiconductors are materials that possess electrical conductivity between that of conductors and insulators, making them essential for various electronic applications, including transistors, diodes, and integrated circuits.Electrical & Electronic EquipmentNot Available
CEDs000138Lubricants?Lubricants are synthetic or petroleum-derived substances used to reduce friction between surfaces in machinery and equipment, enhancing operational efficiency and longevity.Energy, oil & gasNot Available
CEDs000147Food packaging?Food packaging often utilizes synthetic chemicals, such as plastics and coatings, to enhance durability, moisture resistance, and shelf life.Food, food processing & cookwareNot Available
CEDs000174Lubricants?Lubricants are synthetic or petroleum-based substances used to reduce friction and wear between moving parts in machinery and equipment.Industrial manufacturing & chemical processingNot Available
CEDs000233Brushes?Brushes used in personal care and cosmetics can be a source of synthetic chemical contamination due to the materials and coatings used in their manufacturing.Personal care & cosmeticsPubChem
CEDs000234Medical devices?Medical devices often incorporate synthetic chemicals in their manufacturing processes, which can contribute to contamination in healthcare settings.Healthcare, pharmaceuticals & veterinary productsNot Available
CEDs000451Carpets and Rugs?Carpets and rugs are commonly manufactured using synthetic fibers such as nylon, polyester, and polypropylene, which can be derived from petrochemical sources.Textiles, leather & furnishingsNot Available
CEDs000454Synthetic textiles?Synthetic textiles are materials derived from man-made fibers, such as polyester, nylon, and acrylic, which are produced through chemical processes involving petrochemicals.Textiles, leather & furnishingsNot Available
CEDs000490Personal care & cosmeticsNot Available
CEDs000492Cell phones?Cell phones contain a variety of synthetic chemicals and materials, including plastics, metals, and glass, which can contribute to environmental contamination.Electrical & Electronic EquipmentNot Available
CEDs000493Capacitors?Capacitors are electronic components that store and release electrical energy, often using dielectric materials that can include synthetic chemicals.Electrical & Electronic EquipmentNot Available
CEDs000496Fencing?Fencing materials, particularly those used in construction and landscaping, can be a source of synthetic chemical contamination due to the treatments and coatings applied for durability and weather resistance.Building & ConstructionPubChem
CEDs000506Antennas?Antennas, commonly used in communication technologies, can be a source of synthetic chemical contamination through the materials and coatings used in their construction.Electrical & Electronic EquipmentPubChem
CEDs000511Conductors Or Conductive Bodies Characterised By The Conductive Materials?Conductors, or conductive bodies, are materials that allow the flow of electrical current, typically made from metals such as copper, aluminum, or silver.Electrical & Electronic EquipmentPubChem
CEDs000513Cores Yokes Or Armatures?Cores, yokes, or armatures are components commonly found in electrical devices, used to facilitate the magnetic and electrical functions within motors, transformers, and generators.Electrical & Electronic EquipmentPubChem
CEDs000516Electric Hearing Aids?Electric hearing aids are small electronic devices designed to amplify sound for individuals with hearing loss.Electrical & Electronic EquipmentPubChem
CEDs000518Electrically Stimulated Smoking Devices?Electrically stimulated smoking devices, commonly known as e-cigarettes or vape pens, utilize electrical components to heat a liquid solution, often containing nicotine, flavorings, and other additives, to produce an aerosol for inhalation.Electrical & Electronic EquipmentPubChem
CEDs000519Electrodes?Electrodes, used in various electrical and electronic applications, can be a source of synthetic chemical contamination due to the materials from which they are constructed and the processes involved in their manufacturing.Electrical & Electronic EquipmentPubChem
CEDs000521Fixed Capacitors And Their Manufacture?Fixed capacitors are passive electronic components used to store and release electrical energy, playing a critical role in various circuits.Electrical & Electronic EquipmentPubChem
CEDs000524Hybrid Capacitors?Hybrid capacitors are energy storage devices that combine the properties of electrolytic and supercapacitors, utilizing a combination of electrochemical principles to achieve higher energy density and power density.Electrical & Electronic EquipmentPubChem
CEDs000539Video Games?Video games, through their production and disposal processes, can be a source of synthetic chemical contamination.Electrical & Electronic EquipmentPubChem
CEDs000543Cellar Tools?Cellar tools, commonly used in wine production and other fermentation processes, may pose a risk of synthetic chemical contamination if not properly maintained or if manufactured from substandard materials.Food, food processing & cookwarePubChem
CEDs000544Fermentation Processes For Beer?Fermentation processes for beer involve the conversion of sugars into alcohol and carbon dioxide by yeast.Food, food processing & cookwarePubChem
CEDs000545Food Preservation?Food preservation often involves the use of synthetic chemicals, such as preservatives, flavor enhancers, and color additives, to extend shelf life and enhance the sensory qualities of food products.Food, food processing & cookwarePubChem
CEDs000546Molasses And Treatment Of Molasses?Molasses is a thick, viscous byproduct of sugar production, derived from the extraction of sugar cane or sugar beet juice.Food, food processing & cookwarePubChem
CEDs000547Preparation Of Malt?Malt preparation involves the germination and drying of cereal grains, primarily barley, to produce malt for brewing and food products.Food, food processing & cookwarePubChem
CEDs000548Preparation Of Vinegar?Vinegar is produced through the fermentation of ethanol by acetic acid bacteria, resulting in a solution that typically contains 4-8% acetic acid.Food, food processing & cookwarePubChem
CEDs000549Preparation Of Wine Or Sparkling Wine?The preparation of wine or sparkling wine involves various stages, including fermentation, aging, and bottling, which can introduce potential sources of synthetic chemical contamination.Food, food processing & cookwarePubChem
CEDs000550Preparation Of Wort?The preparation of wort involves the extraction of sugars from malted grains, a crucial step in the brewing process.Food, food processing & cookwarePubChem
CEDs000551Processing Fish?Processing fish can lead to synthetic chemical contamination through various stages of production and preservation.Food, food processing & cookwarePubChem
CEDs000552Processing Meats?Processing meats can lead to synthetic chemical contamination primarily through the use of additives and preservatives.Food, food processing & cookwarePubChem
CEDs000553Treatment Of Hops?Hops, a key ingredient in brewing and food flavoring, can be a source of synthetic chemical contamination due to various agricultural practices.Food, food processing & cookwarePubChem
CEDs000555Bleaching Agents?Bleaching agents are chemical substances used to whiten or lighten materials, often employed in various cleaning products for their stain removal and disinfecting properties.Household cleaning & consumer productsPubChem
CEDs000556Cigar Cigarettes?Cigar cigarettes are a source of synthetic chemical contamination due to the combustion of various tobacco blends and additives.Household cleaning & consumer productsPubChem
CEDs000559Non Electric Simulated Smoking Devices?Non-electric simulated smoking devices, often designed to mimic the experience of smoking without combustion, can be sources of synthetic chemical contamination due to the materials and chemicals used in their construction and operation.Household cleaning & consumer productsPubChem
CEDs000560Other Smoking Requisites?Other smoking requisites, including items such as lighters, matches, and rolling papers, can introduce synthetic chemical contamination through various components and additives.Household cleaning & consumer productsPubChem
CEDs000561Perfumes Within Detergents And Soaps?Perfumes within detergents and soaps are synthetic fragrance compounds added to enhance the sensory experience of cleaning products.Household cleaning & consumer productsPubChem
CEDs000562Pipe Accessories?Pipe accessories, such as fittings, connectors, and seals, are components used in plumbing systems to facilitate the flow of liquids and gases.Household cleaning & consumer productsPubChem
CEDs000563Soap Detergents?Soap detergents are synthetic surfactants designed to enhance the cleaning efficacy of water by reducing surface tension, allowing for better interaction with dirt and grease.Household cleaning & consumer productsPubChem
CEDs000564Soap Dispensers?Soap dispensers, commonly used for dispensing liquid soaps and sanitizers, can become a source of synthetic chemical contamination due to the materials used in their construction and the products they dispense.Household cleaning & consumer productsPubChem
CEDs000566Tobacco Pipes?Tobacco pipes, often made from materials such as plastic, wood, or metal, can serve as sources of synthetic chemical contamination due to the residues left by tobacco products.Household cleaning & consumer productsPubChem
CEDs000567Tobacco Product Cases?Tobacco product cases can serve as a source of synthetic chemical contamination due to the presence of various additives and chemicals used in tobacco processing and product manufacturing.Household cleaning & consumer productsPubChem
CEDs000569Tobacco Smoke Filters?Tobacco smoke filters are designed to reduce the inhalation of harmful substances in cigarette smoke, including tar and other particulate matter.Household cleaning & consumer productsPubChem
CEDs000578Making Cigars?The process of making cigars involves several steps, including the cultivation of tobacco, fermentation, and the application of various additives to enhance flavor and preservation.Industrial manufacturing & chemical processingPubChem
CEDs000580Manufacture Preparation Of Tobacco Products?The manufacture and preparation of tobacco products involve various processes that can result in the introduction of synthetic chemicals into the environment.Industrial manufacturing & chemical processingPubChem
CEDs000581Paper Making Machines?Paper making machines utilize various synthetic chemicals throughout the production process, including additives, coatings, and bleaching agents.Industrial manufacturing & chemical processingPubChem
CEDs000596Acaricides?Acaricides are synthetic chemicals specifically designed to target and control mite populations that can damage crops and plants.Agriculture & land managementPubChem
CEDs000597Chemosterilants?Chemosterilants are synthetic chemicals designed to induce sterility in target pest populations, thereby controlling their reproduction and mitigating damage to crops.Agriculture & land managementPubChem
CEDs000598Fertiliser Distributors?Fertiliser distributors play a critical role in the supply of synthetic fertilizers, which are widely used to enhance soil fertility and crop yield.Agriculture & land managementPubChem
CEDs000600Herbicides And Algicides?Herbicides and algicides are synthetic chemicals primarily used to control unwanted plants and algae in various environments.Agriculture & land managementPubChem
CEDs000601Lawn Mowers?Lawn mowers, particularly those powered by gasoline, can be a source of synthetic chemical contamination due to the combustion of fossil fuels and the use of engine oils.Agriculture & land managementPubChem
CEDs000602Molluscicides?Molluscicides are synthetic chemicals specifically designed to control and eliminate mollusks, such as snails and slugs, which can be detrimental to crops and agricultural productivity.Agriculture & land managementPubChem
CEDs000603Nematocides?Nematocides are synthetic chemicals specifically designed to control nematodes, which are microscopic roundworms that can cause significant damage to crops and plants.Agriculture & land managementPubChem
CEDs000604Pest Attractants?Pest attractants are synthetic chemicals designed to lure specific pests for monitoring or control purposes.Agriculture & land managementPubChem
CEDs000605Pest Repellants?Pest repellents, often formulated from synthetic chemicals, are widely used to protect crops from insect infestations and other pests.Agriculture & land managementPubChem
CEDs000606Plant Growth Regulators?Plant Growth Regulators (PGRs) are synthetic chemicals designed to influence the growth and development of plants.Agriculture & land managementPubChem
CEDs000607Rodenticides(1)?Rodenticides are synthetic chemicals specifically formulated to control rodent populations, serving as a crucial tool in managing pests that can damage crops and spread diseases.Agriculture & land managementPubChem
CEDs000608Rodenticides?Rodenticides are chemical substances specifically designed to control rodent populations by causing death through various mechanisms, including anticoagulation or neurotoxicity.Agriculture & land managementPubChem
CEDs000609Aftershave?Aftershave is a grooming product typically used to soothe and protect the skin following shaving.Personal care & cosmeticsPubChem
CEDs000610Aftersun Products?Aftersun products are designed to soothe and hydrate the skin after sun exposure, often containing various synthetic chemicals such as emollients, preservatives, and fragrances.Personal care & cosmeticsPubChem
CEDs000611Anti Perspirants Or Body Deoderants?Antiperspirants and body deodorants commonly contain synthetic chemicals such as aluminum compounds, parabens, and synthetic fragrances.Personal care & cosmeticsPubChem
CEDs000612Body Washing Or Cleaning Implements?Body washing or cleaning implements, such as synthetic sponges, loofahs, and washcloths, can be sources of synthetic chemical contamination due to the materials used in their production.Personal care & cosmeticsPubChem
CEDs000613Depilatories?Depilatories are products designed to remove unwanted hair through the application of synthetic chemicals that break down the protein structure of hair, facilitating its removal.Personal care & cosmeticsPubChem
CEDs000614Essential Oils Or Perfumes?Essential oils and perfumes are complex mixtures of volatile compounds derived from natural or synthetic sources, commonly used for their aromatic properties.Personal care & cosmeticsPubChem
CEDs000615Eye Makeup Products?Eye makeup products, including mascaras, eyeliners, and eyeshadows, often contain a variety of synthetic chemicals such as pigments, preservatives, and film-forming agents.Personal care & cosmeticsPubChem
CEDs000616Face Mask Cosmetics?Face mask cosmetics often contain a variety of synthetic chemicals, including preservatives, emulsifiers, and fragrances, which can contribute to chemical contamination.Personal care & cosmeticsPubChem
CEDs000617Lip Care Products?Lip care products, including lipsticks, balms, and glosses, often contain a variety of synthetic chemicals such as parabens, phthalates, and synthetic fragrances.Personal care & cosmeticsPubChem
CEDs000618Lip Makeup Products?Lip makeup products, such as lipsticks, lip glosses, and lip liners, often contain a variety of synthetic chemicals, including pigments, preservatives, and emollients.Personal care & cosmeticsPubChem
CEDs000619Manicure Pedicure?Manicure and pedicure procedures often involve the use of various synthetic chemicals, including solvents, nail polishes, and nail adhesives.Personal care & cosmeticsPubChem
CEDs000632Apparel?Apparel production often involves the use of various synthetic chemicals, including dyes, finishing agents, and preservatives.Textiles, leather & furnishingsPubChem
CEDs000634Buckles?Buckles, commonly used as fasteners in clothing, accessories, and furniture, can be a source of synthetic chemical contamination due to the materials and coatings employed in their production.Textiles, leather & furnishingsPubChem
CEDs000638Decorating Textiles?Decorating textiles often involves the use of synthetic chemicals such as dyes, finishes, and coatings.Textiles, leather & furnishingsPubChem
CEDs000642Footwear?Footwear production often involves the use of various synthetic chemicals, such as adhesives, dyes, and treatments, which can contribute to environmental contamination.Textiles, leather & furnishingsPubChem
CEDs000643Headwear?Headwear made from synthetic materials often incorporates chemicals used in the manufacturing and finishing processes, such as dyes, flame retardants, and water repellents.Textiles, leather & furnishingsPubChem
CEDs000656Snap Fasteners?Snap fasteners, commonly used in clothing and upholstery, can be made from various synthetic materials, including plastics and metal alloys.Textiles, leather & furnishingsPubChem
CEDs000657Surface Finishing Of Leather?Surface finishing of leather often involves the use of various synthetic chemicals, including dyes, resins, and finishing agents.Textiles, leather & furnishingsPubChem
CEDs000658Touch Fasteners?Touch fasteners, commonly known as hook-and-loop fasteners, are composed of synthetic materials such as nylon or polyester.Textiles, leather & furnishingsPubChem
CEDs000662Yarns Or Threads?Yarns or threads used in textiles can be a source of synthetic chemical contamination due to the production processes and treatments they undergo.Textiles, leather & furnishingsPubChem
CEDs000671Airplanes And Helicopters?Airplanes and helicopters are significant sources of synthetic chemical contamination primarily through the use of aviation fuels, lubricants, and de-icing agents.Aviation & AerospacePubChem
CEDs000673Unmanned Aerial Vehicles?Unmanned Aerial Vehicles (UAVs), commonly known as drones, utilize various synthetic chemicals in their manufacturing, operation, and maintenance processes.Aviation & AerospacePubChem
CEDs000678Nitrogenous Fertilisers?Nitrogenous fertilizers are synthetic chemical compounds primarily used to enhance plant growth by supplying essential nitrogen, a crucial nutrient for photosynthesis and protein synthesis.Agriculture & land managementPubChem
CEDs000679Phosphatic Fertilisers?Phosphatic fertilizers are synthetic chemical products primarily composed of phosphorus, which is essential for plant growth.Agriculture & land managementPubChem
CEDs000684Cements?Cements are a composite material primarily used as a binding agent in construction applications, formed by the calcination of limestone and clay minerals at high temperatures.Building & ConstructionPubChem
CEDs000685Ceramics?Ceramics can be a source of synthetic chemical contamination through various additives and processing agents used in their production.Building & ConstructionPubChem
CEDs000686Clay Wares?Clay wares are ceramic products made from natural clay, often utilized in various construction applications such as tiles, bricks, and sanitary ware.Building & ConstructionPubChem
CEDs000688Glass Coatings?Glass coatings are synthetic chemical formulations applied to glass surfaces to enhance properties such as durability, UV resistance, and aesthetic appeal.Building & ConstructionPubChem
CEDs000689Glass Fibres?Glass fibres are composed of fine strands of glass, commonly utilized for their tensile strength and lightweight properties.Building & ConstructionPubChem
CEDs000693Silica Glass?Silica glass, primarily composed of silicon dioxide (SiO2), is widely used in various applications, including windows, glass facades, and insulation materials.Building & ConstructionPubChem
CEDs000696Nanotechnology?Nanotechnology involves the manipulation of materials at the molecular or atomic level, typically within the range of 1 to 100 nanometers.Industrial manufacturing & chemical processingPubChem
CEDs000727Printing Machines Or Presses?Printing machines or presses commonly utilize synthetic chemicals such as inks, solvents, and cleaning agents.Paper, pulp & fiber productsPubChem
CEDs000734Coating Compositions?Coating compositions, which include paints, sealants, and varnishes, are formulated with a variety of synthetic chemicals such as solvents, resins, pigments, and additives.Building & ConstructionPubChem
CEDs000735Explosives?Explosives are chemical compounds or mixtures designed to undergo rapid decomposition, releasing energy in the form of gas and heat.Defense & military infrastructurePubChem
CEDs000739Inks?Inks are complex mixtures composed of pigments or dyes, solvents, resins, and additives used primarily for printing and writing applications.Paper, pulp & fiber productsPubChem
CEDs000740Paper?Paper production involves the processing of wood fibers and the use of various chemicals, which can lead to synthetic chemical contamination.Paper, pulp & fiber productsPubChem, PMC8839646
CEDs000741Pigment Pastes?Pigment pastes are concentrated dispersions of pigments used to impart color and properties to materials.Paper, pulp & fiber productsPubChem
CEDs000742Leather Tanning?Leather tanning is a process that transforms raw animal hides into durable leather through the application of various chemicals, including chromium salts, aldehydes, and vegetable tannins.Textiles, leather & furnishingsPubChem
CEDs000743Sludge Treatment?Sludge treatment involves the processing of waste materials generated from wastewater treatment plants, which often contain a variety of organic and inorganic substances.Wastewater, sanitation & biosolidsPubChem
CEDs000744Water, Wastewater, & Sewage Treatment?Water, wastewater, and sewage treatment processes are critical for managing and mitigating pollutants in water systems.Wastewater, sanitation & biosolidsPubChem
CEDs00745Corn OilAgriculture & land managementPMC8293095 , PMC9623090
CEDs00748Animal FeedAgriculture & land managementPMC5849680
CEDs00751FeedAgriculture & land managementPMC3998679 , PMC7035566
CEDs00774Agricultural By-productsAgriculture & land managementPMC13209716
CEDs00775FeedsAgriculture & land managementPMC12845879 , PMC10462632
CEDs00782RhizosphereAgriculture & land managementPMC12737786
CEDs00784Feed AdditivesAgriculture & land managementPMC12747205
CEDs00800Soybean OilAgriculture & land managementPMC10931103 , PMC10931103
CEDs00849Poultry FeedAgriculture & land managementPMC5849680
CEDs01078OintmentsHealthcare, pharmaceuticals & veterinary productsPMC7288015
CEDs01080CapsuleHealthcare, pharmaceuticals & veterinary productsPMC10607042
CEDs01143DietFood, food processing & cookwarePMC3515069 , PMC8615418
CEDs01144FoodFood, food processing & cookwarePMC9731903 , PMC9369763
CEDs01145BeveragesFood, food processing & cookwarePMC12406335 , PMC5849680
CEDs01151FruitsFood, food processing & cookwarePMC11910587 , PMC8869647
CEDs01155Red WineFood, food processing & cookwarePMC4665427 , PMC8868221
CEDs01157FoodsFood, food processing & cookwarePMC8997561 , PMC12008688
CEDs01160CerealsFood, food processing & cookwarePMC2835915
CEDs01173Green Leafy VegetablesFood, food processing & cookwarePMC8509433
CEDs01180Edible PlantsFood, food processing & cookwarePMC8293095
CEDs01185Apple JuiceFood, food processing & cookwarePMC6567126
CEDs01186Fruit JuicesFood, food processing & cookwarePMC2835915
CEDs01191CoffeeFood, food processing & cookwarePMC9136617
CEDs01195YogurtFood, food processing & cookwarePMC12008688
CEDs01198HoneyFood, food processing & cookwarePMC11546825 , PMC9826852
CEDs01200VegetablesFood, food processing & cookwarePMC11910587 , PMC8869647
CEDs01201DietsFood, food processing & cookwarePMC12466796 , PMC9781893
CEDs01202Olive OilFood, food processing & cookwarePMC13200494 , PMC10556381
CEDs01203Fruit ExtractsFood, food processing & cookwarePMC11184148
CEDs01204Fruit SamplesFood, food processing & cookwarePMC5802727
CEDs01208FruitFood, food processing & cookwarePMC6128642 , PMC11421477
CEDs01210Food SupplementsFood, food processing & cookwarePMC5713201 , PMC9781893
CEDs01216Artificial DietFood, food processing & cookwarePMC5311835 , PMC5311835
CEDs01223Green TeaFood, food processing & cookwarePMC6719974 , PMC7587910
CEDs01231WinesFood, food processing & cookwarePMC11732501 , PMC7560058
CEDs01238Functional FoodsFood, food processing & cookwarePMC13164702 , PMC13073250
CEDs01239TeaFood, food processing & cookwarePMC12630495 , PMC8997561
CEDs01246Citrus FruitsFood, food processing & cookwarePMC7823819 , PMC6383545
CEDs01253Dietary SupplementsFood, food processing & cookwarePMC9781893 , PMC13073250
CEDs01263Food SourcesFood, food processing & cookwarePMC11200558 , PMC11300909
CEDs01279Vegetable SamplesFood, food processing & cookwarePMC11462967
CEDs01302WineFood, food processing & cookwarePMC8997561 , PMC4670692
CEDs01305Black TeaFood, food processing & cookwarePMC2841576 , PMC4575953
CEDs01310Leafy Green VegetablesFood, food processing & cookwarePMC4665427
CEDs01312Sugar WaterFood, food processing & cookwarePMC5698444
CEDs01322Artificial DietsFood, food processing & cookwarePMC5311835
CEDs01337Green Tea ExtractFood, food processing & cookwarePMC5874576
CEDs01340Plant-based FoodsFood, food processing & cookwarePMC12348896
CEDs01367Red WinesFood, food processing & cookwarePMC12630495 , PMC7070704
CEDs01398Pomegranate JuiceFood, food processing & cookwarePMC4820567
CEDs01452Plant FoodsFood, food processing & cookwarePMC5483489
CEDs01453Citrus FruitFood, food processing & cookwarePMC4665427
CEDs01455Food SimulantFood, food processing & cookwarePMC6960804
CEDs01459CerealFood, food processing & cookwarePMC9457803
CEDs01495Fruit ExtractFood, food processing & cookwarePMC6017451
CEDs01560Beverage SamplesFood, food processing & cookwarePMC10180927
CEDs01564Dietary SourcesFood, food processing & cookwarePMC3966338
CEDs01570Dietary SupplementFood, food processing & cookwarePMC7504053
CEDs01618ChocolatesFood, food processing & cookwarePMC6245372
CEDs01634White TeaFood, food processing & cookwarePMC11990172
CEDs01643Honeydew HoneysFood, food processing & cookwarePMC11275487
CEDs01644Honeydew HoneyFood, food processing & cookwarePMC11275487
CEDs01661Basal DietFood, food processing & cookwarePMC7035566
CEDs01673BeebreadFood, food processing & cookwarePMC5698444
CEDs01675Food PlantsFood, food processing & cookwarePMC9530316
CEDs01699Mulberry FruitFood, food processing & cookwarePMC12346983
CEDs01721TC juiceFood, food processing & cookwarePMC12296803 , PMC12296803
CEDs01744Edible PartFood, food processing & cookwarePMC9229746
CEDs01756Zucchini FruitFood, food processing & cookwarePMC9854589 , PMC9854589
CEDs01782Edible FlowersFood, food processing & cookwarePMC10343634
CEDs01801Food PackagingPackagingPMC8198733
CEDs01826Glass BottlesPackagingPMC8198733
CEDs01900Epoxy ResinIndustrial manufacturing & chemical processingPMC11051280
CEDs01969Natural RubberIndustrial manufacturing & chemical processingPMC12431393
CEDs02005Rubber MatricesIndustrial manufacturing & chemical processingPMC10819226
CEDs02255WaterAquatic systems & sedimentsPMC11910587 , PMC8198733
CEDs02739GlueBuilding & ConstructionPMC12263532
CEDs02762Dental AdhesiveBuilding & ConstructionPMC11942969
CEDs02815Glass Ionomer CementBuilding & ConstructionPMC5551883
Pathways
0 pathwaysPathway Source: PathBank

No pathways found

No metabolic pathways have been associated with this synthetic chemical

Targets
StructureProteinUniProt IDOrganismRelationshipDetails
Click to view 3D structureD-alanine--D-alanine ligaseQ1CTD3Helicobacter pylori (strain HPAG1)Predicted (SEA)
Prediction Confidence Score
1.0
Applicability Domain
1.0
Statistical Significance
1.00e-05
Supporting Reference Compounds
1
E-value
0.0778492
Pancreatic triacylglycerol lipase structureClick to view 3D structurePancreatic triacylglycerol lipaseP16233HumansKnownNot Available
Aldo-keto reductase family 1 member C21 structureClick to view 3D structureAldo-keto reductase family 1 member C21Q91WR5Mus musculusPredicted (SEA)
Prediction Confidence Score
1.0
Applicability Domain
1.0
Statistical Significance
1.00e-05
Supporting Reference Compounds
1
E-value
0.0778492
Click to view 3D structureInositol hexakisphosphate kinase 2Q9UHH9HumansPredicted (SEA)
Prediction Confidence Score
0.8
Applicability Domain
1.0
Statistical Significance
1.00e-05
Supporting Reference Compounds
13
E-value
0.0778492
Cytochrome P450 1B1 structureClick to view 3D structureCytochrome P450 1B1Q16678HumansPredicted (SEA)
Prediction Confidence Score
0.796
Applicability Domain
1.0
Statistical Significance
1.00e-05
Supporting Reference Compounds
88
E-value
0.0778492
Cytochrome P450 1A1 structureClick to view 3D structureCytochrome P450 1A1P04798HumansPredicted (SEA)
Prediction Confidence Score
0.796
Applicability Domain
1.0
Statistical Significance
1.00e-05
Supporting Reference Compounds
77
E-value
0.0778492
Xanthine dehydrogenase/oxidase structureClick to view 3D structureXanthine dehydrogenase/oxidaseP47989HumansPredicted (SEA)
Prediction Confidence Score
0.796
Applicability Domain
1.0
Statistical Significance
1.00e-05
Supporting Reference Compounds
37
E-value
0.0778492
Angiotensin-converting enzyme structureClick to view 3D structureAngiotensin-converting enzymeP12821HumansKnownNot Available
ATP-dependent translocase ABCB1 structureClick to view 3D structureATP-dependent translocase ABCB1P08183HumansPredicted (SEA)
Prediction Confidence Score
0.78
Applicability Domain
1.0
Statistical Significance
4.00e-05
Supporting Reference Compounds
139
E-value
0.311397
Solute carrier family 12 member 2 structureClick to view 3D structureSolute carrier family 12 member 2P55011HumansKnownNot Available
Cytochrome P450 1A2 structureClick to view 3D structureCytochrome P450 1A2P05177HumansPredicted (SEA)
Prediction Confidence Score
0.779
Applicability Domain
1.0
Statistical Significance
1.00e-05
Supporting Reference Compounds
793
E-value
0.0778492
Aldo-keto reductase family 1 member B1 structureClick to view 3D structureAldo-keto reductase family 1 member B1P15121HumansPredicted (SEA)
Prediction Confidence Score
0.775
Applicability Domain
1.0
Statistical Significance
2.00e-05
Supporting Reference Compounds
84
E-value
0.155698
Protein deacetylase HDAC6 structureClick to view 3D structureProtein deacetylase HDAC6Q9UBN7HumansPredicted (SEA)
Prediction Confidence Score
0.773
Applicability Domain
1.0
Statistical Significance
2.00e-05
Supporting Reference Compounds
553
E-value
0.155698
Inositol polyphosphate multikinase structureClick to view 3D structureInositol polyphosphate multikinaseQ8NFU5HumansPredicted (SEA)
Prediction Confidence Score
0.771
Applicability Domain
1.0
Statistical Significance
1.00e-05
Supporting Reference Compounds
6
E-value
0.0778492
Receptor-type tyrosine-protein kinase FLT3 structureClick to view 3D structureReceptor-type tyrosine-protein kinase FLT3P36888HumansPredicted (SEA)
Prediction Confidence Score
0.771
Applicability Domain
1.0
Statistical Significance
5.00e-05
Supporting Reference Compounds
1274
E-value
0.389246
Short transient receptor potential channel 5 structureClick to view 3D structureShort transient receptor potential channel 5Q9UL62HumansPredicted (SEA)
Prediction Confidence Score
0.771
Applicability Domain
1.0
Statistical Significance
1.00e-05
Supporting Reference Compounds
21
E-value
0.0778492
Click to view 3D structure3-oxoacyl-acyl-carrier protein reductaseQ965D6Plasmodium falciparumPredicted (SEA)
Prediction Confidence Score
0.766
Applicability Domain
1.0
Statistical Significance
1.00e-05
Supporting Reference Compounds
12
E-value
0.0778492
Carbonic anhydrase 2 structureClick to view 3D structureCarbonic anhydrase 2P00918HumansPredicted (SEA)
Prediction Confidence Score
0.764
Applicability Domain
1.0
Statistical Significance
2.00e-05
Supporting Reference Compounds
472
E-value
0.155698
Carbonic anhydrase 7 structureClick to view 3D structureCarbonic anhydrase 7P43166HumansPredicted (SEA)
Prediction Confidence Score
0.764
Applicability Domain
1.0
Statistical Significance
1.00e-05
Supporting Reference Compounds
242
E-value
0.0778492
Carbonic anhydrase 12 structureClick to view 3D structureCarbonic anhydrase 12O43570HumansPredicted (SEA)
Prediction Confidence Score
0.764
Applicability Domain
1.0
Statistical Significance
1.00e-05
Supporting Reference Compounds
332
E-value
0.0778492
Cytochrome P450 2E1 structureClick to view 3D structureCytochrome P450 2E1P05181HumansKnownNot Available
Mitogen-activated protein kinase structureClick to view 3D structureMitogen-activated protein kinaseA3FQ79Cryptosporidium parvum (strain Iowa II)KnownNot Available
Carbonic anhydrase 1 structureClick to view 3D structureCarbonic anhydrase 1P00915HumansPredicted (SEA)
Prediction Confidence Score
0.764
Applicability Domain
1.0
Statistical Significance
2.00e-05
Supporting Reference Compounds
407
E-value
0.155698
Cholinesterase structureClick to view 3D structureCholinesteraseP06276HumansKnownNot Available
Carbonic anhydrase 4 structureClick to view 3D structureCarbonic anhydrase 4P22748HumansPredicted (SEA)
Prediction Confidence Score
0.764
Applicability Domain
1.0
Statistical Significance
1.00e-05
Supporting Reference Compounds
193
E-value
0.0778492
Click to view 3D structureEnoyl-acyl-carrier protein reductaseQ965D5Plasmodium falciparumPredicted (SEA)
Prediction Confidence Score
0.761
Applicability Domain
1.0
Statistical Significance
1.00e-05
Supporting Reference Compounds
18
E-value
0.0778492
Amyloid-beta precursor protein structureClick to view 3D structureAmyloid-beta precursor proteinP05067HumansPredicted (SEA)
Prediction Confidence Score
0.759
Applicability Domain
1.0
Statistical Significance
1.00e-05
Supporting Reference Compounds
109
E-value
0.0778492
Click to view 3D structureTyrosine-protein kinase transforming protein FpsP00530Fujinami sarcoma virusPredicted (SEA)
Prediction Confidence Score
0.757
Applicability Domain
0.757
Statistical Significance
1.00e-05
Supporting Reference Compounds
1
E-value
0.0778492
Amine oxidase [flavin-containing] A structureClick to view 3D structureAmine oxidase [flavin-containing] AP21397HumansPredicted (SEA)
Prediction Confidence Score
0.749
Applicability Domain
1.0
Statistical Significance
2.00e-05
Supporting Reference Compounds
241
E-value
0.155698
Click to view 3D structureGag-Pol polyproteinQ7ZJM1Human immunodeficiency virus 1Predicted (SEA)
Prediction Confidence Score
0.746
Applicability Domain
1.0
Statistical Significance
1.00e-05
Supporting Reference Compounds
96
E-value
0.0778492
Alpha-ketoglutarate-dependent dioxygenase FTO structureClick to view 3D structureAlpha-ketoglutarate-dependent dioxygenase FTOQ9C0B1HumansPredicted (SEA)
Prediction Confidence Score
0.735
Applicability Domain
1.0
Statistical Significance
1.00e-05
Supporting Reference Compounds
36
E-value
0.0778492
Catalase structureClick to view 3D structureCatalaseP04040HumansKnownNot Available
RAC-alpha serine/threonine-protein kinase structureClick to view 3D structureRAC-alpha serine/threonine-protein kinaseP31749HumansKnownNot Available
G-protein coupled estrogen receptor 1 structureClick to view 3D structureG-protein coupled estrogen receptor 1Q99527HumansKnownNot Available
Aldehyde oxidase structureClick to view 3D structureAldehyde oxidaseQ06278HumansKnownNot Available
Mitogen-activated protein kinase kinase kinase 5 structureClick to view 3D structureMitogen-activated protein kinase kinase kinase 5Q99683HumansKnownNot Available
Albumin structureClick to view 3D structureAlbuminP02768HumansKnownNot Available
Transcription factor Jun structureClick to view 3D structureTranscription factor JunP05412HumansKnownNot Available
Phosphatidylinositol 3-kinase regulatory subunit alpha structureClick to view 3D structurePhosphatidylinositol 3-kinase regulatory subunit alphaP27986HumansKnownNot Available
Click to view 3D structureUDP-glucuronosyltransferase 1A6P19224HumansKnownNot Available
Insulin receptor structureClick to view 3D structureInsulin receptorP06213HumansKnownNot Available
Aromatase structureClick to view 3D structureAromataseP11511HumansKnownNot Available
Serine/threonine-protein kinase mTOR structureClick to view 3D structureSerine/threonine-protein kinase mTORP42345HumansKnownNot Available
Sulfotransferase 1E1 structureClick to view 3D structureSulfotransferase 1E1P49888HumansKnownNot Available
Click to view 3D structureCytochrome P450 1A1P00185RatKnownNot Available
Tyrosinase structureClick to view 3D structureTyrosinaseP14679HumansKnownNot Available
Interferon regulatory factor 5 structureClick to view 3D structureInterferon regulatory factor 5Q13568HumansKnownNot Available
Caspase-3 structureClick to view 3D structureCaspase-3P42574HumansKnownNot Available
Aryl hydrocarbon receptor structureClick to view 3D structureAryl hydrocarbon receptorP35869HumansKnownNot Available
Cytochrome P450 1B1 structureClick to view 3D structureCytochrome P450 1B1Q16678HumansKnownNot Available
Nuclear factor erythroid 2-related factor 2 structureClick to view 3D structureNuclear factor erythroid 2-related factor 2Q16236HumansKnownNot Available
Serine/threonine-protein kinase TBK1 structureClick to view 3D structureSerine/threonine-protein kinase TBK1Q9UHD2HumansKnownNot Available
Xanthine dehydrogenase structureClick to view 3D structureXanthine dehydrogenaseO54050Rhodobacter capsulatusKnownNot Available
ATP-binding cassette sub-family C member 2 structureClick to view 3D structureATP-binding cassette sub-family C member 2Q92887HumansKnownNot Available
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha structureClick to view 3D structurePeroxisome proliferator-activated receptor gamma coactivator 1-alphaQ9UBK2HumansKnownNot Available
Click to view 3D structureUDP-glucuronosyltransferase 1A9O60656HumansKnownNot Available
Cytochrome P450 2C8 structureClick to view 3D structureCytochrome P450 2C8P10632HumansKnownNot Available
Click to view 3D structureUDP-glucuronosyltransferase 1A3P35503HumansKnownNot Available
Estrogen receptor structureClick to view 3D structureEstrogen receptorP03372HumansKnownNot Available
Click to view 3D structureUDP-glucuronosyltransferase 1A1P22309HumansKnownNot Available
Vitronectin structureClick to view 3D structureVitronectinP04004HumansKnownNot Available
Tumor necrosis factor structureClick to view 3D structureTumor necrosis factorP01375HumansKnownNot Available
Furin structureClick to view 3D structureFurinP09958HumansKnownNot Available
Sulfotransferase 1A1 structureClick to view 3D structureSulfotransferase 1A1P50225HumansKnownNot Available
Click to view 3D structureFlavin-containing monooxygenase 5P49326HumansKnownNot Available
Taste receptor type 2 member 14 structureClick to view 3D structureTaste receptor type 2 member 14Q9NYV8HumansKnownNot Available
Cytochrome c structureClick to view 3D structureCytochrome cP99999HumansKnownNot Available
Click to view 3D structureTaste receptor type 2 member 39P59534HumansKnownNot Available
Thioredoxin-interacting protein structureClick to view 3D structureThioredoxin-interacting proteinQ9H3M7HumansKnownNot Available
Catechol O-methyltransferase structureClick to view 3D structureCatechol O-methyltransferaseP21964HumansKnownNot Available
Cytochrome P450 1A2 structureClick to view 3D structureCytochrome P450 1A2P05177HumansKnownNot Available
Cytochrome P450 3A4 structureClick to view 3D structureCytochrome P450 3A4P08684HumansKnownNot Available
Glucose-6-phosphatase catalytic subunit 1 structureClick to view 3D structureGlucose-6-phosphatase catalytic subunit 1P35575HumansKnownNot Available
Acetylcholinesterase structureClick to view 3D structureAcetylcholinesteraseP22303HumansKnownNot Available
Tyrosine-protein kinase HCK structureClick to view 3D structureTyrosine-protein kinase HCKP08631HumansKnownNot Available
3-hydroxyisobutyryl-CoA hydrolase, mitochondrial structureClick to view 3D structure3-hydroxyisobutyryl-CoA hydrolase, mitochondrialQ6NVY1HumansKnownNot Available
ATP synthase F(1) complex subunit alpha, mitochondrial structureClick to view 3D structureATP synthase F(1) complex subunit alpha, mitochondrialP25705HumansKnownNot Available
ATP synthase F(1) complex subunit beta, mitochondrial structureClick to view 3D structureATP synthase F(1) complex subunit beta, mitochondrialP06576HumansKnownNot Available
ATP synthase F(1) complex subunit gamma, mitochondrial structureClick to view 3D structureATP synthase F(1) complex subunit gamma, mitochondrialP36542HumansKnownNot Available
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform structureClick to view 3D structurePhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoformP48736HumansKnownNot Available
Serine/threonine-protein kinase 17B structureClick to view 3D structureSerine/threonine-protein kinase 17BO94768HumansKnownNot Available
Serine/threonine-protein kinase pim-1 structureClick to view 3D structureSerine/threonine-protein kinase pim-1P11309HumansKnownNot Available
Click to view 3D structureUDP-glucuronosyltransferase 3A1Q6NUS8HumansKnownNot Available
Glycogen synthase kinase-3 beta structureClick to view 3D structureGlycogen synthase kinase-3 betaP49841HumansKnownNot Available
Estrogen receptor beta structureClick to view 3D structureEstrogen receptor betaQ92731HumansKnownNot Available
Adenosine receptor A2a structureClick to view 3D structureAdenosine receptor A2aP29274HumansKnownNot Available
Concentrations
Not Available
External Links
DrugBank IDDB04216
HMDB IDHMDB0005794
FooDB IDFDB011904
Phenol Explorer ID291
KNApSAcK IDC00004631
BiGG IDNot Available
BioCyc IDCPD-520
METLIN IDNot Available
PDB IDQUE
Wikipedia LinkQuercetin
Chemspider ID4444051
ChEBI ID16243
PubChem Compound ID5280343
Kegg Compound IDC00389
YMDB IDYMDB01777
ECMDB IDECMDB23201
References
Synthesis Reference

Miguel M. Taya, Dionisio M. Aedo, Rene Ricard, “Quercetin pentamethyl carbamate and a process for its preparation.” U.S. Patent US4202825, issued October, 1975.

MSDSLink
General References
  1. Perez-Vizcaino F, Duarte J, Andriantsitohaina R: Endothelial function and cardiovascular disease: effects of quercetin and wine polyphenols. Free Radic Res. 2006 Oct;40(10):1054-65. [PubMed: 17015250]
  2. International Agency for Research on Cancer (2014). IARC Monographs on the Evaluation of Carcinogenic Risks to Humans. - http://monographs.iarc.fr/index.php