Tetraethylene Glycol (CHEM003758)

Record Information
Version1.0
Creation Date2014-09-11 05:17:13 UTC
Update Date2026-08-24 18:07:34 UTC
Accession NumberCHEM003758
Identification
Common NameTetraethylene Glycol
ClassSmall Molecule
Description
Tetraethylene glycol is an industrial solvent/chemical with a higher boiling point and lower volatility than the lower ethylene glycols. It is especially useful in polyester resins and as a plasticizer. Tetraethylene glycol is also used as a chemical intermediate and as a solvent in the production of inks and dyes. Tetraethylene glycol is often used as a process solvent in hydrocarbon purification processes and as a coupling agent in the production of textile lubricants and formulations.
Contaminant Sources
  • HPV EPA Chemicals
  • OECD HPV Chemicals
  • STOFF IDENT Compounds
  • Suspected Compounds
  • T3DB toxins
  • ToxCast & Tox21 Chemicals
Contaminant Type
  • Dye
  • Ether
  • Household Toxin
  • Industrial/Workplace Toxin
  • Organic Compound
  • Plasticizer
  • Solvent
  • Synthetic Compound
Chemical Structure
MOLSDF3D SDFPDBSMILESInChI View 3D Structure
Synonyms
ValueSource
2,2'-[Oxybis(2,1-ethanediyloxy)]bisethanolChEBI
2,2'-[Oxybis(2,1-ethanediyloxy)]diethanolChEBI
2-(2-[2-(2-Hydroxyethoxy)ethoxy]ethoxy)ethanolChEBI
3,6,9-Trioxaundecan-1,11-diolChEBI
3,6,9-Trioxaundecane-1,11-diolChEBI
PEG-4ChEBI
GlycofurolHMDB
Tetrahydrofurfuryl alcohol polyethylene glycol etherHMDB
TetraglycolHMDB
Chromophore elHMDB
Chemical FormulaC8H18O5
Average Molecular Mass194.226 g/mol
Monoisotopic Mass194.115 g/mol
CAS Registry Number112-60-7
IUPAC Name2-{2-[2-(2-hydroxyethoxy)ethoxy]ethoxy}ethan-1-ol
Traditional Nametetraethylene glycol
SMILESOCCOCCOCCOCCO
InChI IdentifierInChI=1S/C8H18O5/c9-1-3-11-5-7-13-8-6-12-4-2-10/h9-10H,1-8H2
InChI KeyUWHCKJMYHZGTIT-UHFFFAOYSA-N
Chemical Taxonomy
Description Belongs to the class of organic compounds known as polyethylene glycols. These are oligomers or polymers of ethylene oxide, with the general formula (C2H4O)n (with n>=3).
KingdomOrganic compounds
Super ClassOrganic oxygen compounds
ClassOrganooxygen compounds
Sub ClassEthers
Direct ParentPolyethylene glycols
Alternative Parents
Substituents
  • Polyethylene glycol
  • Hydrocarbon derivative
  • Primary alcohol
  • Alcohol
  • Aliphatic acyclic compound
Molecular FrameworkAliphatic acyclic compounds
External Descriptors
Biological Properties
StatusDetected and Not Quantified
OriginExogenous
Cellular Locations
  • Cytoplasm
  • Extracellular
Biofluid LocationsNot Available
Tissue LocationsNot Available
PathwaysNot Available
ApplicationsNot Available
Biological RolesNot Available
Chemical RolesNot Available
Physical Properties
StateLiquid
AppearanceNot Available
Experimental Properties
PropertyValue
Melting Point-6.2 °C
Boiling Point328 °C
Solubility1E+006 mg/L (at 20 °C)
Predicted Properties
PropertyValueSource
Water Solubility106 g/LALOGPS
logP-0.98ALOGPS
logP-1.3ChemAxon
logS-0.26ALOGPS
pKa (Strongest Acidic)14.82ChemAxon
pKa (Strongest Basic)-2.7ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count5ChemAxon
Hydrogen Donor Count2ChemAxon
Polar Surface Area68.15 ŲChemAxon
Rotatable Bond Count10ChemAxon
Refractivity47.68 m³·mol⁻¹ChemAxon
Polarizability21.77 ųChemAxon
Number of Rings0ChemAxon
BioavailabilityYesChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon
Spectra
Spectra
Toxicity Profile
Route of ExposureNot Available
Mechanism of ToxicityNot Available
MetabolismNot Available
Toxicity ValuesNot Available
Lethal DoseNot Available
Carcinogenicity (IARC Classification)No indication of carcinogenicity to humans (not listed by IARC).
Uses/SourcesNot Available
Minimum Risk LevelNot Available
Health EffectsNot Available
SymptomsNot Available
TreatmentNot Available
Concentrations
Not Available
External Links
DrugBank IDDB02575
HMDB IDHMDB0094708
FooDB IDNot Available
Phenol Explorer IDNot Available
KNApSAcK IDNot Available
BiGG IDNot Available
BioCyc IDNot Available
METLIN IDNot Available
PDB IDNot Available
Wikipedia LinkPolyethylene glycol
Chemspider IDNot Available
ChEBI ID44920
PubChem Compound ID8200
Kegg Compound IDNot Available
YMDB IDNot Available
ECMDB IDNot Available
References
Synthesis ReferenceNot Available
MSDSNot Available
General References