ASTAXANTHIN (CED0002457)

Record Information
Version1.0
Creation Date2016-05-19 01:54:49 UTC
Update Date2026-05-14 18:21:25 UTC
SynCED IDCED0002457
Secondary Accession Numbers
  • CHEM004786
Identification
Common NameASTAXANTHIN
ClassSmall Molecule
Description
ASTAXANTHIN belongs to the tetraterpenoids, a subclass of prenol lipids within the organic compounds. With an average molecular weight of 596.85 g/mol, ASTAXANTHIN is a heavy molecule. Its chemical formula is C40H52O4. This compound acts as a biological metabolite (PMC8955251 ) and biological agonist (PMC6878783 ), while serving as a biological and industrial antioxidant (PMC10214356 , PMC10220911 ). Industrially, it is used as a dye and a softener and conditioner (PMC10214356 , PMC10220911 ), and environmentally, it functions as a nutrient (PMC6878783 ). Biologically, it acts as an anti-inflammatory agent (PMC5793074 ) and targets the protein NF-kappa-B inhibitor alpha (NFKBIA). ASTAXANTHIN is recorded in several sources, including tobacco product cases, antennas, video games, and food, food processing, and cookware, specifically the processing of fish and the preparation of wine or sparkling wine, vinegar, and malt. It is a treatment for cancer (PMC10641005 ), neuropathic pain (PMC8955251 ), and Parkinson's disease (PMC7333894 ). It has therapeutic effects on cancer (PMC11981035 , PMC5793074 ), inflammation (PMC11273418 , PMC12780283 ), hyperglycemia (PMC12732708 , PMC6878783 ), diabetic neuropathy (PMC6878783 ), arteriosclerosis (PMC11273418 , PMC6891815 ), atherosclerosis (PMC4262001 ), memory impairment (PMC12709879 ), acute pancreatitis (PMC13317055 ), obesity (PMC8955251 ), hypertension (PMC8955251 ), blood pressure (PMC8955251 ), COVID-19 (PMC8955251 ), stroke (PMC8955251 ), the liver (PMC7736086 ), pulmonary fibrosis (PMC4626686 ), and fibrosarcoma (PMC9229179 ). Additionally, it is associated with inflammation (PMC6878783 ), obesity (PMC10454148 ), arthritis (PMC9204945 ), and cancer (PMC9204945 ).
Contaminant TypeNot Available
Chemical Structure
Synonyms
ValueSource
(3S,3's)-AstaxanthinChEBI
3,3'-Dihydroxy-beta,beta-carotene-4,4'-dioneChEBI
3,3'-Dihydroxy-beta-carotene-4,4'-dioneChEBI
all-trans-(3S,3's)-AstaxanthinChEBI
AstaxanthineChEBI
e 161JChEBI
OvoesterChEBI
(3S,3's)-3,3'-Dihydroxy-beta,beta-carotene-4,4'-dioneKegg
3,3'-Dihydroxy-b,b-carotene-4,4'-dioneGenerator
3,3'-Dihydroxy-β,β-carotene-4,4'-dioneGenerator
3,3'-Dihydroxy-b-carotene-4,4'-dioneGenerator
3,3'-Dihydroxy-β-carotene-4,4'-dioneGenerator
(3S,3's)-3,3'-Dihydroxy-b,b-carotene-4,4'-dioneGenerator
(3S,3's)-3,3'-Dihydroxy-β,β-carotene-4,4'-dioneGenerator
(3S,3's)-all-trans-AstaxanthinHMDB
all-trans-3,3'-Dihydroxy-b-carotene-4,4'-dione (8ci)HMDB
all-trans-3,3'-Dihydroxy-beta-carotene-4,4'-dione (8ci)HMDB
all-trans-AstaxanthinHMDB
AstaREALHMDB
Astaxanthin (6ci)HMDB
BioAstinHMDB
BioAstin oleoresinHMDB
Carophyll pinkHMDB
Lucantin pinkHMDB
NatupinkHMDB
trans-AstaxanthinHMDB
e-AstaxanthinHMDB
(3S,3’S)-3,3’-dihydroxy-β,β-carotene-4,4’-dioneHMDB
(3S,3’S)-astaxanthinHMDB
(3S,3’S)-all-trans-astaxanthinHMDB
(S,S)-AstaxanthinHMDB
all-trans-(3S,3’S)-astaxanthinHMDB
AstaxanthinHMDB
Chemical FormulaC40H52O4
Average Molecular Mass596.852 g/mol
Monoisotopic Mass596.387 g/mol
CAS Registry Number472-61-7
IUPAC Name(6S)-6-hydroxy-3-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-18-[(4S)-4-hydroxy-2,6,6-trimethyl-3-oxocyclohex-1-en-1-yl]-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaen-1-yl]-2,4,4-trimethylcyclohex-2-en-1-one
Traditional Nameastaxanthin
SMILESC\C(\C=C\C=C(/C)\C=C\C1=C(C)C(=O)[C@@H](O)CC1(C)C)=C/C=C/C=C(\C)/C=C/C=C(\C)/C=C/C1=C(C)C(=O)[C@@H](O)CC1(C)C
InChI IdentifierInChI=1S/C40H52O4/c1-27(17-13-19-29(3)21-23-33-31(5)37(43)35(41)25-39(33,7)8)15-11-12-16-28(2)18-14-20-30(4)22-24-34-32(6)38(44)36(42)26-40(34,9)10/h11-24,35-36,41-42H,25-26H2,1-10H3/b12-11+,17-13+,18-14+,23-21+,24-22+,27-15+,28-16+,29-19+,30-20+/t35-,36-/m0/s1
InChI KeyMQZIGYBFDRPAKN-UWFIBFSHSA-N
Chemical Taxonomy
Description Belongs to the class of organic compounds known as xanthophylls. These are carotenoids containing an oxygenated carotene backbone. Carotenes are characterized by the presence of two end-groups (mostly cyclohexene rings, but also cyclopentene rings or acyclic groups) linked by a long branched alkyl chain. Carotenes belonging form a subgroup of the carotenoids family. Xanthophylls arise by oxygenation of the carotene backbone.
KingdomOrganic compounds
Super ClassLipids and lipid-like molecules
ClassPrenol lipids
Sub ClassTetraterpenoids
Direct ParentXanthophylls
Alternative Parents
Substituents
  • Xanthophyll
  • Cyclohexenone
  • Cyclic ketone
  • Secondary alcohol
  • Ketone
  • Organic oxygen compound
  • Organic oxide
  • Hydrocarbon derivative
  • Organooxygen compound
  • Carbonyl group
  • Alcohol
  • Aliphatic homomonocyclic compound
Molecular FrameworkAliphatic homomonocyclic compounds
External Descriptors
Biological Properties
StatusDetected and Not Quantified
OriginNot Available
Cellular LocationsNot Available
Biofluid LocationsNot Available
Tissue LocationsNot Available
ApplicationsNot Available
Biological Roles
Chemical RolesNot Available
Organoleptic Effects
  • yellow colour ?
  • red colour ?
  • orange colour ?
  • bright red colour ?
  • orange-red colour ?
  • pink colour ?
  • meat colour ?
  • deep red colour ?
  • red-orange colour ?
  • dark red colour ?
  • reddish orange colour ?
  • reddish colour ?
  • orange-reddish colour ?
  • reddish pink colour ?
  • pink-orange colour ?
Physical Properties
StateNot Available
AppearanceNot Available
Experimental Properties
PropertyValue
Melting PointNot Available
Boiling PointNot Available
SolubilityNot Available
Predicted Properties
PropertyValueSource
Water Solubility0.00067 g/LALOGPS
logP7.4ALOGPS
logP8.05ChemAxon
logS-6ALOGPS
pKa (Strongest Acidic)13.07ChemAxon
pKa (Strongest Basic)-3.5ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count4ChemAxon
Hydrogen Donor Count2ChemAxon
Polar Surface Area74.6 ŲChemAxon
Rotatable Bond Count10ChemAxon
Refractivity195.98 m³·mol⁻¹ChemAxon
Polarizability73.77 ųChemAxon
Number of Rings2ChemAxon
BioavailabilityNoChemAxon
Rule of FiveNoChemAxon
Ghose FilterNoChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon
Spectra
Spectra
Spectrum TypeDescriptionSplash KeyDeposition DateView
Predicted GC-MSPredicted GC-MS Spectrumsplash10-001i-2000090000-c6336112eb898c2f0a48Not AvailableView Spectrum
Predicted GC-MSPredicted GC-MS Spectrumsplash10-0udi-3000019000-6b5720849187b199d6bfNot AvailableView Spectrum
Predicted GC-MSPredicted GC-MS SpectrumNot AvailableNot AvailableView Spectrum
Predicted GC-MSPredicted GC-MS SpectrumNot AvailableNot AvailableView Spectrum
Predicted GC-MSPredicted GC-MS SpectrumNot AvailableNot AvailableView Spectrum
Predicted GC-MSPredicted GC-MS SpectrumNot AvailableNot AvailableView Spectrum
Predicted GC-MSPredicted GC-MS SpectrumNot AvailableNot AvailableView Spectrum
Predicted GC-MSPredicted GC-MS SpectrumNot AvailableNot AvailableView Spectrum
Predicted GC-MSPredicted GC-MS SpectrumNot AvailableNot AvailableView Spectrum
Predicted GC-MSPredicted GC-MS SpectrumNot AvailableNot AvailableView Spectrum
Predicted GC-MSPredicted GC-MS SpectrumNot AvailableNot AvailableView Spectrum
Predicted GC-MSPredicted GC-MS SpectrumNot AvailableNot AvailableView Spectrum
Predicted GC-MSPredicted GC-MS SpectrumNot AvailableNot AvailableView Spectrum
Predicted GC-MSPredicted GC-MS SpectrumNot AvailableNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0002-0961030000-dc7a74c186ee85f204faNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0002-0961030000-368bb77cba4aef27a5cbNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0002-0000090000-ce16b33770cb7a4b2ff7Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-0002-0232390000-f37e3530214c99f63306Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-004i-1296830000-ac8ea41a53a053acb7c8Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-03fr-0185910000-7af6a00762ad7e8ee75dNot AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-0002-0000090000-248171e80348a7e1d17eNot AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-0002-0000090000-b9759de23c7494bb7b2dNot AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-004i-0333390000-074ea5de5d017bafdb5eNot AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-004m-0142590000-4e72a5bda186fd51912cNot AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-03fr-0195650000-3ee8ba797d4a2fb9c80fNot AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-01u3-0013900000-71e9a6336700d9e8fca6Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-0002-0001090000-836dc358b0a566457c26Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-004j-0117190000-07d5d205542df36e4f5bNot AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-002b-0239230000-7be6270484a4c641a468Not AvailableView Spectrum
1D NMR13C NMR Spectrum (1D, H2O, predicted)Not AvailableNot AvailableView Spectrum
1D NMR1H NMR Spectrum (1D, H2O, predicted)Not AvailableNot AvailableView Spectrum
Toxicity Profile
Toxicity Values
Toxicity ValueOrganismDose DescriptorRoute of ExposurePredicted or ExperimentalToxicity RatingReference
3789.0 Log mg/kg [2100:6700]RatLD50oralpredictedNot AvailableNot Available
Toxicity / Toxin ClassNot Available
Mechanism of ToxicityNot Available
Carcinogenicity (IARC Classification)Not Available
Minimum Risk LevelNot Available
SymptomsNot Available
TreatmentNot Available
Health Effects
Health EffectRelationshipDirectionDescriptionReference
arthritisAssociated With?Not AvailableA disorder characterized by inflammation involving a joint. (NCI CTCAE)PMC9204945
hypertensionHas Therapeutic Effect OnNot AvailableA disorder characterized by a pathological increase in blood pressure; a repeatedly elevation in the blood pressure exceeding 140 over 90 mm Hg. (NCI CTCAE)PMC8955251
blood pressureHas Therapeutic Effect OnNot AvailableNot AvailablePMC8955251
inflammationHas Therapeutic Effect OnNot AvailableNot AvailablePMC11273418 , PMC12780283
inflammationAssociated With?Not AvailableNot AvailablePMC6878783 , PMC12343168
inflammationNot AvailableNot AvailableNot AvailablePMC8534595
cancerAssociated With?Not AvailableCancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. Possible signs and symptoms include a lump, abnormal bleeding, prolonged cough, unexplained weight loss, and a change in bowel movements. There are over 100 types of cancers affect humans. The risk of developing certain cancers can be reduced by not smoking, maintaining a healthy weight, not drinking too much alcohol, eating plenty of vegetables, fruits and whole grains, vaccination against certain infectious diseases, not eating too much processed and red meat and avoiding too much sunlight exposure. Cancer is often treated with some combination of radiation therapy, surgery, chemotherapy and targeted therapy. The majority of cancers, some 90–95% of cases, are due to genetic mutations from environmental and lifestyle factors. The remaining 5–10% are due to inherited genetics.PMC9204945 , PMC10220911
cancerHas Therapeutic Effect OnNot AvailableCancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. Possible signs and symptoms include a lump, abnormal bleeding, prolonged cough, unexplained weight loss, and a change in bowel movements. There are over 100 types of cancers affect humans. The risk of developing certain cancers can be reduced by not smoking, maintaining a healthy weight, not drinking too much alcohol, eating plenty of vegetables, fruits and whole grains, vaccination against certain infectious diseases, not eating too much processed and red meat and avoiding too much sunlight exposure. Cancer is often treated with some combination of radiation therapy, surgery, chemotherapy and targeted therapy. The majority of cancers, some 90–95% of cases, are due to genetic mutations from environmental and lifestyle factors. The remaining 5–10% are due to inherited genetics.PMC11981035 , PMC5793074
cancerNot AvailableNot AvailableCancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. Possible signs and symptoms include a lump, abnormal bleeding, prolonged cough, unexplained weight loss, and a change in bowel movements. There are over 100 types of cancers affect humans. The risk of developing certain cancers can be reduced by not smoking, maintaining a healthy weight, not drinking too much alcohol, eating plenty of vegetables, fruits and whole grains, vaccination against certain infectious diseases, not eating too much processed and red meat and avoiding too much sunlight exposure. Cancer is often treated with some combination of radiation therapy, surgery, chemotherapy and targeted therapy. The majority of cancers, some 90–95% of cases, are due to genetic mutations from environmental and lifestyle factors. The remaining 5–10% are due to inherited genetics.PMC10641005 , PMC5856442
cancerAssociated With?decreaseCancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. Possible signs and symptoms include a lump, abnormal bleeding, prolonged cough, unexplained weight loss, and a change in bowel movements. There are over 100 types of cancers affect humans. The risk of developing certain cancers can be reduced by not smoking, maintaining a healthy weight, not drinking too much alcohol, eating plenty of vegetables, fruits and whole grains, vaccination against certain infectious diseases, not eating too much processed and red meat and avoiding too much sunlight exposure. Cancer is often treated with some combination of radiation therapy, surgery, chemotherapy and targeted therapy. The majority of cancers, some 90–95% of cases, are due to genetic mutations from environmental and lifestyle factors. The remaining 5–10% are due to inherited genetics.PMC8955125
Alzheimer's diseaseNot AvailableNot AvailableA neurodegenerative disease which causes neural atrophy, leading to dementia and memory loss.PMC8955251
breast cancerAssociated With?Not AvailableA breast cancer that has material basis in abnormally proliferating cells derives from epithelial cells. (DO)PMC12809803
type 2 diabetes mellitusHas Therapeutic Effect OnNot AvailableNot AvailablePMC6878783 , PMC8027776
type 2 diabetes mellitusNot AvailableNot AvailableNot AvailablePMC6878783 , PMC11566087
overweightHas Therapeutic Effect OnNot AvailableNot AvailablePMC7916866
fatigueAssociated With?Not AvailableA disorder characterized by a state of generalized weakness with a pronounced inability to summon sufficient energy to accomplish daily activities. (NCI CTCAE)PMC10870688
diabetes mellitusHas Therapeutic Effect OnNot AvailableA glucose metabolism disease characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both. (DO)PMC6878783 , PMC9204945
diabetes mellitusNot AvailableNot AvailableA glucose metabolism disease characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both. (DO)PMC5793074 , PMC10641005
strokeHas Therapeutic Effect OnNot AvailableNot AvailablePMC8955251 , PMC10525378
strokeAssociated With?decreaseNot AvailablePMC10525378
neuropathic painNot AvailableNot AvailableNot AvailablePMC8955251
Prostate cancerHas Therapeutic Effect OnNot AvailableA male reproductive organ cancer that is located in the prostate. (DO)PMC5793074 , PMC10227411
colon cancerHas Therapeutic Effect OnNot AvailableNot AvailablePMC8122763
obesityHas Therapeutic Effect OnNot AvailableA disorder characterized by having a high amount of body fat. (NCI CTCAE)PMC8955251 , PMC8534595
obesityAssociated With?Not AvailableA disorder characterized by having a high amount of body fat. (NCI CTCAE)PMC10454148
obesityNot AvailableNot AvailableA disorder characterized by having a high amount of body fat. (NCI CTCAE)PMC5037659
atherosclerosisHas Therapeutic Effect OnNot AvailableA disorder involving build-up of fatty material and calcium deposition in the arterial wall. It results in partial or complete occlusion of the arterial lumen.PMC4262001 , PMC8534595
COVID-19Has Therapeutic Effect OnNot AvailableNot AvailablePMC8955251
myocardial infarctionHas Therapeutic Effect OnNot AvailableA disorder characterized by gross necrosis of the myocardium; this is due to an interruption of blood supply to the area. (NCI CTCAE)PMC8955251
liverHas Therapeutic Effect OnNot AvailableNot AvailablePMC7736086
liver diseaseHas Therapeutic Effect OnNot AvailableA disorder characterized by any variety of factors leading to damage to the liver.PMC12709879 , PMC5484137
arteriosclerosisHas Therapeutic Effect OnNot AvailableAn artery disease that is characterized by a thickening and hardening of arterial walls in the arteries. (DO)PMC11273418 , PMC6891815
acute pancreatitisHas Therapeutic Effect OnNot AvailableNot AvailablePMC13317055
memory impairmentHas Therapeutic Effect OnNot AvailableA disorder characterized by a deterioration in memory function. (NCI CTCAE)PMC12709879
atopic dermatitisHas Therapeutic Effect OnNot AvailableNot AvailablePMC10214356
diseaseHas Therapeutic Effect OnNot AvailableNot AvailablePMC5484137
hyperglycemiaHas Therapeutic Effect OnNot AvailableA disorder characterized by laboratory test results that indicate an elevation in the concentration of blood sugar. It is usually an indication of diabetes mellitus or glucose intolerance. (NCI CTCAE)PMC12732708 , PMC6878783
pulmonary fibrosisHas Therapeutic Effect OnNot AvailableNot AvailablePMC4626686
diabetic neuropathyHas Therapeutic Effect OnNot AvailableNot AvailablePMC6878783
Parkinson's diseaseNot AvailableNot AvailableA long-term degenerative disorder of the central nervous system that mainly affects the motor system. The symptoms generally come on slowly over time.PMC7333894
inflammatory bowel diseaseHas Therapeutic Effect OnNot AvailableAn intestinal disease characterized by inflammation located in all parts of digestive tract. (DO)PMC8534595
neurodegenerative diseaseHas Therapeutic Effect OnNot AvailableA central nervous system disease that results in the progressive deterioration of function or structure of neurons. (DO)PMC6486502 , PMC7333894
cerebral infarctionHas Therapeutic Effect OnNot AvailableAn ischemic condition of the brain, producing a persistent focal neurological deficit in the area of distribution of the cerebral arteries.PMC10525378
cataractHas Therapeutic Effect OnNot AvailableA disorder characterized by partial or complete opacity of the crystalline lens of one or both eyes. This results in a decrease in visual acuity and eventual blindness if untreated. (NCI CTCAE)PMC4262001
fibrosarcomaHas Therapeutic Effect OnNot AvailableA connective tissue cancer that has material basis in fibrous connective tissue and characterized by the presence of immature proliferating fibroblasts or undifferentiated anaplastic spindle cells in a storiform pattern. (DO)PMC9229179
brain diseaseHas Therapeutic Effect OnNot AvailableNot AvailablePMC11273418
macular degenerationHas Therapeutic Effect OnNot AvailableA retinal degeneration characterized by gradual deterioration of light-sensing cells in the tissues at the back of the eye and has symptom vision loss. (DO)PMC4262001 , PMC9204945
hepatic fibrosisNot AvailableNot AvailableNot AvailablePMC5037659
hepatic fibrosisAssociated With?Not AvailableNot AvailablePMC6164583
gastric ulcerHas Therapeutic Effect OnNot AvailableA disorder characterized by a circumscribed, inflammatory and necrotic erosive lesion on the mucosal surface of the stomach lining.PMC6486502
steatotic liver diseaseHas Therapeutic Effect OnNot AvailableNot AvailablePMC12588746 , PMC6164583
skin diseaseHas Therapeutic Effect OnNot AvailableNot AvailablePMC7736086 , PMC5484137
eye diseaseHas Therapeutic Effect OnNot AvailableNot AvailablePMC6486502 , PMC5484137
urinary bladder cancerHas Therapeutic Effect OnNot AvailableNot AvailablePMC6268471
Cell DeathHas Therapeutic Effect OnNot AvailableNot AvailablePMC8389241
abdominal obesity-metabolic syndromeHas Therapeutic Effect OnNot AvailableNot AvailablePMC6486502 , PMC5484137
Abnormality of mitochondrial metabolismHas Therapeutic Effect OnNot AvailableNot AvailablePMC7333894
Oxidative StressHas Therapeutic Effect OnNot AvailableNot AvailablePMC11273418 , PMC12709879
Oxidative StressAssociated With?Not AvailableNot AvailablePMC6878783 , PMC8623138
Oxidative StressIs Biomarker OfNot AvailableNot AvailablePMC10819827
injuryHas Therapeutic Effect OnNot AvailableNot AvailablePMC8389241
cardiovascular disorderHas Therapeutic Effect OnNot AvailableNot AvailablePMC11273418 , PMC4262001
cardiovascular disorderAssociated With?Not AvailableNot AvailablePMC9204945 , PMC10220911
DNA DamageHas Therapeutic Effect OnNot AvailableNot AvailablePMC9098901 , PMC5793074
inflammatory diseaseAssociated With?Not AvailableNot AvailablePMC12655362
inflammatory diseaseHas Therapeutic Effect OnNot AvailableNot AvailablePMC6486502 , PMC8142882
SepsisNot AvailableNot AvailableNot AvailablePMC8540215
disease of metabolismHas Therapeutic Effect OnNot AvailableNot AvailablePMC12647431
nervous system disorderHas Therapeutic Effect OnNot AvailableNot AvailablePMC11273418
Growth delayHas Therapeutic Effect OnNot AvailableNot AvailablePMC12588746
AIDSHas Therapeutic Effect OnNot AvailableNot AvailablePMC9204945
NeoplasmsHas Therapeutic Effect OnNot AvailableNot AvailablePMC5793074 , PMC11981035
infectious diseaseHas Therapeutic Effect OnNot AvailableNot AvailablePMC4262001 , PMC11464810
NeuroinflammationHas Therapeutic Effect OnNot AvailableNot AvailablePMC12709879 , PMC7736086
immune system disorderHas Therapeutic Effect OnNot AvailableNot AvailablePMC8540215
AgingAssociated With?Not AvailableNot AvailablePMC6164583
AgingHas Therapeutic Effect OnNot AvailableNot AvailablePMC8389241
gastrointestinal system diseaseHas Therapeutic Effect OnNot AvailableNot AvailablePMC5484137
metabolic dysfunction-associated steatotic liver diseaseAssociated With?Not AvailableNot AvailablePMC6164583
NeurodegenerationHas Therapeutic Effect OnNot AvailableNot AvailablePMC9204945
NeurodegenerationAssociated With?Not AvailableNot AvailablePMC12343168
age related macular degenerationAssociated With?Not AvailableNot AvailablePMC10220911
ischemia reperfusion injuryHas Therapeutic Effect OnNot AvailableNot AvailablePMC13462034
ulcer diseaseHas Therapeutic Effect OnNot AvailableNot AvailablePMC8955251 , PMC6628611
Neurodegenerative DiseasesNot AvailableNot AvailableNot AvailablePMC7333894
Neurodegenerative DiseasesAssociated With?Not AvailableNot AvailablePMC10604131
diabetic kidney diseaseHas Therapeutic Effect OnNot AvailableNot AvailablePMC6486502 , PMC5484137
Skin AgingHas Therapeutic Effect OnNot AvailableNot AvailablePMC11783858
hyperlipidemiaHas Therapeutic Effect OnNot AvailableNot AvailablePMC8955251
ErythemaHas Therapeutic Effect OnNot AvailableNot AvailablePMC9545714
primary ovarian insufficiencyHas Therapeutic Effect OnNot AvailableNot AvailablePMC9098901
Wound HealingHas Therapeutic Effect OnNot AvailableNot AvailablePMC10214356
Muscle FatigueHas Therapeutic Effect OnNot AvailableNot AvailablePMC10215677
Hyperpigmentation of the skinNot AvailableNot AvailableNot AvailablePMC5793074
cytokine release syndromeHas Therapeutic Effect OnNot AvailableNot AvailablePMC8955251
Intestinal inflammationHas Therapeutic Effect OnNot AvailableNot AvailablePMC12780283
Prostatic HyperplasiaHas Therapeutic Effect OnNot AvailableNot AvailablePMC11981035
ElasticityHas Therapeutic Effect OnNot AvailableNot AvailablePMC13115732 , PMC9545714
PigmentationHas Therapeutic Effect OnNot AvailableNot AvailablePMC13115732
Autophagic Cell DeathHas Therapeutic Effect OnNot AvailableNot AvailablePMC8389241
atherosclerotic cardiovascular diseaseAssociated With?decreaseNot AvailablePMC8955125
Hepatic cystsAssociated With?Not AvailableNot AvailablePMC11303046
Exposure Sources
Source IDSourceSectorReference
CEDs000010Insecticides?Insecticides are synthetic chemicals designed to control or eliminate insect pests that threaten crops and other agricultural products.Agriculture & land managementPubChem
CEDs000048Marine sediment?Marine sediment can serve as a significant reservoir for synthetic chemical contaminants, which may originate from various anthropogenic activities.Aquatic systems & sedimentsPMC4262001
CEDs000070Stormwater runoff?Stormwater runoff refers to the flow of rainwater or melted snow that does not soak into the ground and instead collects pollutants as it travels over impervious surfaces such as roads and parking lots.Automotive & urban infrastructurePubChem
CEDs000146Food additives?Food additives are substances added to food products to enhance flavor, appearance, preservation, or nutritional value.Food, food processing & cookwarePMC11766884
CEDs000217Sunscreen?Sunscreen products often contain synthetic chemicals such as oxybenzone, octinoxate, and avobenzone, which are used for their UV-filtering properties.Personal care & cosmeticsPMC11783858
CEDs000222Lotions?Lotions are emulsified formulations primarily composed of water, oils, and various active ingredients designed for skin hydration and protection.Personal care & cosmeticsPMC12709879
CEDs000233Brushes?Brushes used in personal care and cosmetics can be a source of synthetic chemical contamination due to the materials and coatings used in their manufacturing.Personal care & cosmeticsPubChem
CEDs000506Antennas?Antennas, commonly used in communication technologies, can be a source of synthetic chemical contamination through the materials and coatings used in their construction.Electrical & Electronic EquipmentPubChem
CEDs000511Conductors Or Conductive Bodies Characterised By The Conductive Materials?Conductors, or conductive bodies, are materials that allow the flow of electrical current, typically made from metals such as copper, aluminum, or silver.Electrical & Electronic EquipmentPubChem
CEDs000517Electric Switches?Electric switches, integral components in numerous devices, can be a source of synthetic chemical contamination due to the materials and manufacturing processes involved in their production.Electrical & Electronic EquipmentPubChem
CEDs000518Electrically Stimulated Smoking Devices?Electrically stimulated smoking devices, commonly known as e-cigarettes or vape pens, utilize electrical components to heat a liquid solution, often containing nicotine, flavorings, and other additives, to produce an aerosol for inhalation.Electrical & Electronic EquipmentPubChem
CEDs000519Electrodes?Electrodes, used in various electrical and electronic applications, can be a source of synthetic chemical contamination due to the materials from which they are constructed and the processes involved in their manufacturing.Electrical & Electronic EquipmentPubChem
CEDs000521Fixed Capacitors And Their Manufacture?Fixed capacitors are passive electronic components used to store and release electrical energy, playing a critical role in various circuits.Electrical & Electronic EquipmentPubChem
CEDs000524Hybrid Capacitors?Hybrid capacitors are energy storage devices that combine the properties of electrolytic and supercapacitors, utilizing a combination of electrochemical principles to achieve higher energy density and power density.Electrical & Electronic EquipmentPubChem
CEDs000539Video Games?Video games, through their production and disposal processes, can be a source of synthetic chemical contamination.Electrical & Electronic EquipmentPubChem
CEDs000544Fermentation Processes For Beer?Fermentation processes for beer involve the conversion of sugars into alcohol and carbon dioxide by yeast.Food, food processing & cookwarePubChem
CEDs000545Food Preservation?Food preservation often involves the use of synthetic chemicals, such as preservatives, flavor enhancers, and color additives, to extend shelf life and enhance the sensory qualities of food products.Food, food processing & cookwarePubChem
CEDs000547Preparation Of Malt?Malt preparation involves the germination and drying of cereal grains, primarily barley, to produce malt for brewing and food products.Food, food processing & cookwarePubChem
CEDs000548Preparation Of Vinegar?Vinegar is produced through the fermentation of ethanol by acetic acid bacteria, resulting in a solution that typically contains 4-8% acetic acid.Food, food processing & cookwarePubChem
CEDs000549Preparation Of Wine Or Sparkling Wine?The preparation of wine or sparkling wine involves various stages, including fermentation, aging, and bottling, which can introduce potential sources of synthetic chemical contamination.Food, food processing & cookwarePubChem
CEDs000551Processing Fish?Processing fish can lead to synthetic chemical contamination through various stages of production and preservation.Food, food processing & cookwarePubChem
CEDs000552Processing Meats?Processing meats can lead to synthetic chemical contamination primarily through the use of additives and preservatives.Food, food processing & cookwarePubChem
CEDs000555Bleaching Agents?Bleaching agents are chemical substances used to whiten or lighten materials, often employed in various cleaning products for their stain removal and disinfecting properties.Household cleaning & consumer productsPubChem
CEDs000556Cigar Cigarettes?Cigar cigarettes are a source of synthetic chemical contamination due to the combustion of various tobacco blends and additives.Household cleaning & consumer productsPubChem
CEDs000561Perfumes Within Detergents And Soaps?Perfumes within detergents and soaps are synthetic fragrance compounds added to enhance the sensory experience of cleaning products.Household cleaning & consumer productsPubChem
CEDs000563Soap Detergents?Soap detergents are synthetic surfactants designed to enhance the cleaning efficacy of water by reducing surface tension, allowing for better interaction with dirt and grease.Household cleaning & consumer productsPubChem
CEDs000567Tobacco Product Cases?Tobacco product cases can serve as a source of synthetic chemical contamination due to the presence of various additives and chemicals used in tobacco processing and product manufacturing.Household cleaning & consumer productsPubChem
CEDs000569Tobacco Smoke Filters?Tobacco smoke filters are designed to reduce the inhalation of harmful substances in cigarette smoke, including tar and other particulate matter.Household cleaning & consumer productsPubChem
CEDs000578Making Cigars?The process of making cigars involves several steps, including the cultivation of tobacco, fermentation, and the application of various additives to enhance flavor and preservation.Industrial manufacturing & chemical processingPubChem
CEDs000580Manufacture Preparation Of Tobacco Products?The manufacture and preparation of tobacco products involve various processes that can result in the introduction of synthetic chemicals into the environment.Industrial manufacturing & chemical processingPubChem
CEDs000581Paper Making Machines?Paper making machines utilize various synthetic chemicals throughout the production process, including additives, coatings, and bleaching agents.Industrial manufacturing & chemical processingPubChem
CEDs000584Buoys?Buoys, often used for navigation and marine monitoring, can be sources of synthetic chemical contamination due to the materials and coatings employed in their construction.Marine, shipping & aquaculturePubChem
CEDs000595Ships?Ships, as vehicles for international trade and transportation, can be significant sources of synthetic chemical contamination in marine environments.Marine, shipping & aquaculturePubChem
CEDs000596Acaricides?Acaricides are synthetic chemicals specifically designed to target and control mite populations that can damage crops and plants.Agriculture & land managementPubChem
CEDs000597Chemosterilants?Chemosterilants are synthetic chemicals designed to induce sterility in target pest populations, thereby controlling their reproduction and mitigating damage to crops.Agriculture & land managementPubChem
CEDs000600Herbicides And Algicides?Herbicides and algicides are synthetic chemicals primarily used to control unwanted plants and algae in various environments.Agriculture & land managementPubChem
CEDs000602Molluscicides?Molluscicides are synthetic chemicals specifically designed to control and eliminate mollusks, such as snails and slugs, which can be detrimental to crops and agricultural productivity.Agriculture & land managementPubChem
CEDs000603Nematocides?Nematocides are synthetic chemicals specifically designed to control nematodes, which are microscopic roundworms that can cause significant damage to crops and plants.Agriculture & land managementPubChem
CEDs000604Pest Attractants?Pest attractants are synthetic chemicals designed to lure specific pests for monitoring or control purposes.Agriculture & land managementPubChem
CEDs000605Pest Repellants?Pest repellents, often formulated from synthetic chemicals, are widely used to protect crops from insect infestations and other pests.Agriculture & land managementPubChem
CEDs000606Plant Growth Regulators?Plant Growth Regulators (PGRs) are synthetic chemicals designed to influence the growth and development of plants.Agriculture & land managementPubChem
CEDs000607Rodenticides(1)?Rodenticides are synthetic chemicals specifically formulated to control rodent populations, serving as a crucial tool in managing pests that can damage crops and spread diseases.Agriculture & land managementPubChem
CEDs000608Rodenticides?Rodenticides are chemical substances specifically designed to control rodent populations by causing death through various mechanisms, including anticoagulation or neurotoxicity.Agriculture & land managementPubChem
CEDs000609Aftershave?Aftershave is a grooming product typically used to soothe and protect the skin following shaving.Personal care & cosmeticsPubChem
CEDs000610Aftersun Products?Aftersun products are designed to soothe and hydrate the skin after sun exposure, often containing various synthetic chemicals such as emollients, preservatives, and fragrances.Personal care & cosmeticsPubChem
CEDs000611Anti Perspirants Or Body Deoderants?Antiperspirants and body deodorants commonly contain synthetic chemicals such as aluminum compounds, parabens, and synthetic fragrances.Personal care & cosmeticsPubChem
CEDs000613Depilatories?Depilatories are products designed to remove unwanted hair through the application of synthetic chemicals that break down the protein structure of hair, facilitating its removal.Personal care & cosmeticsPubChem
CEDs000614Essential Oils Or Perfumes?Essential oils and perfumes are complex mixtures of volatile compounds derived from natural or synthetic sources, commonly used for their aromatic properties.Personal care & cosmeticsPubChem
CEDs000615Eye Makeup Products?Eye makeup products, including mascaras, eyeliners, and eyeshadows, often contain a variety of synthetic chemicals such as pigments, preservatives, and film-forming agents.Personal care & cosmeticsPubChem
CEDs000616Face Mask Cosmetics?Face mask cosmetics often contain a variety of synthetic chemicals, including preservatives, emulsifiers, and fragrances, which can contribute to chemical contamination.Personal care & cosmeticsPubChem
CEDs000617Lip Care Products?Lip care products, including lipsticks, balms, and glosses, often contain a variety of synthetic chemicals such as parabens, phthalates, and synthetic fragrances.Personal care & cosmeticsPubChem
CEDs000618Lip Makeup Products?Lip makeup products, such as lipsticks, lip glosses, and lip liners, often contain a variety of synthetic chemicals, including pigments, preservatives, and emollients.Personal care & cosmeticsPubChem
CEDs000619Manicure Pedicure?Manicure and pedicure procedures often involve the use of various synthetic chemicals, including solvents, nail polishes, and nail adhesives.Personal care & cosmeticsPubChem
CEDs000632Apparel?Apparel production often involves the use of various synthetic chemicals, including dyes, finishing agents, and preservatives.Textiles, leather & furnishingsPubChem
CEDs000650Purses Luggage Hand Bags?Purses, luggage, and handbags are often manufactured using synthetic materials such as polyvinyl chloride (PVC), polyurethane, and various types of nylon.Textiles, leather & furnishingsPubChem
CEDs000657Surface Finishing Of Leather?Surface finishing of leather often involves the use of various synthetic chemicals, including dyes, resins, and finishing agents.Textiles, leather & furnishingsPubChem
CEDs000662Yarns Or Threads?Yarns or threads used in textiles can be a source of synthetic chemical contamination due to the production processes and treatments they undergo.Textiles, leather & furnishingsPubChem
CEDs000671Airplanes And Helicopters?Airplanes and helicopters are significant sources of synthetic chemical contamination primarily through the use of aviation fuels, lubricants, and de-icing agents.Aviation & AerospacePubChem
CEDs000678Nitrogenous Fertilisers?Nitrogenous fertilizers are synthetic chemical compounds primarily used to enhance plant growth by supplying essential nitrogen, a crucial nutrient for photosynthesis and protein synthesis.Agriculture & land managementPubChem
CEDs000679Phosphatic Fertilisers?Phosphatic fertilizers are synthetic chemical products primarily composed of phosphorus, which is essential for plant growth.Agriculture & land managementPubChem
CEDs000685Ceramics?Ceramics can be a source of synthetic chemical contamination through various additives and processing agents used in their production.Building & ConstructionPubChem
CEDs000696Nanotechnology?Nanotechnology involves the manipulation of materials at the molecular or atomic level, typically within the range of 1 to 100 nanometers.Industrial manufacturing & chemical processingPubChem
CEDs000697Submarines?Submarines, while essential for military and research purposes, can be a source of synthetic chemical contamination due to their use of various industrial chemicals.Marine, shipping & aquaculturePubChem
CEDs000727Printing Machines Or Presses?Printing machines or presses commonly utilize synthetic chemicals such as inks, solvents, and cleaning agents.Paper, pulp & fiber productsPubChem
CEDs000730Contact Lens Cases?Contact lens cases are small containers designed to store contact lenses in a sterile environment, typically made from various synthetic materials including plastics such as polypropylene or polycarbonate.Healthcare, pharmaceuticals & veterinary productsPubChem
CEDs000734Coating Compositions?Coating compositions, which include paints, sealants, and varnishes, are formulated with a variety of synthetic chemicals such as solvents, resins, pigments, and additives.Building & ConstructionPubChem
CEDs000738Cooling Circuit Water?Cooling circuit water is utilized in various industrial processes to absorb and dissipate heat generated during operations.Industrial manufacturing & chemical processingPubChem
CEDs000739Inks?Inks are complex mixtures composed of pigments or dyes, solvents, resins, and additives used primarily for printing and writing applications.Paper, pulp & fiber productsPubChem
CEDs000740Paper?Paper production involves the processing of wood fibers and the use of various chemicals, which can lead to synthetic chemical contamination.Paper, pulp & fiber productsPubChem
CEDs000741Pigment Pastes?Pigment pastes are concentrated dispersions of pigments used to impart color and properties to materials.Paper, pulp & fiber productsPubChem
CEDs000743Sludge Treatment?Sludge treatment involves the processing of waste materials generated from wastewater treatment plants, which often contain a variety of organic and inorganic substances.Wastewater, sanitation & biosolidsPubChem
CEDs000744Water, Wastewater, & Sewage Treatment?Water, wastewater, and sewage treatment processes are critical for managing and mitigating pollutants in water systems.Wastewater, sanitation & biosolidsPubChem
CEDs00745Corn OilAgriculture & land managementPMC6164583
CEDs00748Animal FeedAgriculture & land managementPMC12655362 , PMC12655362
CEDs00749CornAgriculture & land managementPMC11273418
CEDs00751FeedAgriculture & land managementPMC11273418 , PMC10161259
CEDs00763Fish FeedAgriculture & land managementPMC4071588
CEDs01079TabletHealthcare, pharmaceuticals & veterinary productsPMC10918363
CEDs01080CapsuleHealthcare, pharmaceuticals & veterinary productsPMC12709879 , PMC8623138
CEDs01081TabletsHealthcare, pharmaceuticals & veterinary productsPMC12709879
CEDs01082PharmaceuticalsHealthcare, pharmaceuticals & veterinary productsPMC10214356 , PMC10734531
CEDs01090Pharmaceutical ProductsHealthcare, pharmaceuticals & veterinary productsPMC8534595
CEDs01143DietFood, food processing & cookwarePMC11464810 , PMC12588746
CEDs01144FoodFood, food processing & cookwarePMC11273418 , PMC11273418
CEDs01145BeveragesFood, food processing & cookwarePMC11273418
CEDs01148MilkFood, food processing & cookwarePMC13317055
CEDs01151FruitsFood, food processing & cookwarePMC11314074 , PMC5852693
CEDs01157FoodsFood, food processing & cookwarePMC6411662 , PMC11273418
CEDs01168Food ProductsFood, food processing & cookwarePMC11273418 , PMC11273418
CEDs01170EggsFood, food processing & cookwarePMC11273418 , PMC8955251
CEDs01177BreadFood, food processing & cookwarePMC7435790
CEDs01181Food ItemsFood, food processing & cookwarePMC7266124 , PMC8956011
CEDs01194CheeseFood, food processing & cookwarePMC7281102
CEDs01195YogurtFood, food processing & cookwarePMC11273418 , PMC11273418
CEDs01200VegetablesFood, food processing & cookwarePMC11314074
CEDs01201DietsFood, food processing & cookwarePMC8534595
CEDs01202Olive OilFood, food processing & cookwarePMC13317055 , PMC7736086
CEDs01210Food SupplementsFood, food processing & cookwarePMC11273418 , PMC10214356
CEDs01226SeafoodFood, food processing & cookwarePMC11273418 , PMC10214356
CEDs01238Functional FoodsFood, food processing & cookwarePMC5640587 , PMC11566087
CEDs01253Dietary SupplementsFood, food processing & cookwarePMC9495708 , PMC13250407
CEDs01259Meat ProductsFood, food processing & cookwarePMC12655362
CEDs01263Food SourcesFood, food processing & cookwarePMC12572074
CEDs01267Egg YolkFood, food processing & cookwarePMC12842758
CEDs01281Food FormulationsFood, food processing & cookwarePMC11273418
CEDs01282Whole Wheat FlourFood, food processing & cookwarePMC11273418
CEDs01283MeatballsFood, food processing & cookwarePMC11273418
CEDs01315Processed FoodFood, food processing & cookwarePMC10214356
CEDs01390ShellfishFood, food processing & cookwarePMC8866108 , PMC10215677
CEDs01433Rice GrainFood, food processing & cookwarePMC8421571
CEDs01570Dietary SupplementFood, food processing & cookwarePMC10641005
CEDs01626SeafoodsFood, food processing & cookwarePMC10215677
CEDs01680Vegetable MatricesFood, food processing & cookwarePMC9598241
CEDs01797PackagingPackagingPMC11273418
CEDs01805Canned FishPackagingPMC10970143
CEDs01917Food IndustryIndustrial manufacturing & chemical processingPMC8955251
CEDs01966OleoresinIndustrial manufacturing & chemical processingPMC13115732 , PMC13115732
CEDs02070WastesWaste management, landfill & incinerationPMC11273418
CEDs02091Shrimp WasteWaste management, landfill & incinerationPMC11273418 , PMC10894098
CEDs02126Waste MaterialWaste management, landfill & incinerationPMC11850539
CEDs02255WaterAquatic systems & sedimentsPMC10608131
CEDs02256Marine EnvironmentAquatic systems & sedimentsPMC13375318
CEDs02280OceanAquatic systems & sedimentsPMC9229179
CEDs02324Freshwater EnvironmentAquatic systems & sedimentsPMC12709879
CEDs02348Aquatic ProductsAquatic systems & sedimentsPMC9098901
CEDs02579Marine AnimalsAquatic systems & sedimentsPMC6093783
CEDs02845CosmeticsPersonal care & cosmeticsPMC8955251 , PMC11766884
CEDs02851CosmeticPersonal care & cosmeticsPMC12655362 , PMC5640587
CEDs02855Cosmetic ProductPersonal care & cosmeticsPMC13115732
CEDs02881Cosmetic IndustriesPersonal care & cosmeticsPMC10220911
CEDs03018Municipal WastewaterWastewater, sanitation & biosolidsPMC13330505
CEDs03420AquacultureMarine, shipping & aquaculturePMC5640587 , PMC13375318
CEDs03421Aquaculture FeedMarine, shipping & aquaculturePMC8955251 , PMC5809543
Pathways
0 pathwaysPathway Source: PathBank

No pathways found

No metabolic pathways have been associated with this synthetic chemical

Targets
StructureProteinUniProt IDOrganismRelationshipDetails
Glutathione reductase structureClick to view 3D structureGlutathione reductaseP06715Escherichia coli (strain K12)KnownNot Available
Cathepsin B structureClick to view 3D structureCathepsin BP07858HumansKnownNot Available
Bile salt-activated lipase structureClick to view 3D structureBile salt-activated lipaseP19835HumansKnownNot Available
Mitogen-activated protein kinase structureClick to view 3D structureMitogen-activated protein kinaseA3FQ79Cryptosporidium parvum (strain Iowa II)KnownNot Available
Click to view 3D structureAldehyde dehydrogenase 1A1P27463Gallus gallusPredicted (SEA)
Prediction Confidence Score
0.397
Applicability Domain
0.397
Statistical Significance
5.00e-05
Supporting Reference Compounds
1
E-value
0.389246
Click to view 3D structureRetinoic acid receptor alphaP11416Mus musculusPredicted (SEA)
Prediction Confidence Score
0.396
Applicability Domain
0.434
Statistical Significance
1.40e-04
Supporting Reference Compounds
16
E-value
1.08989
Click to view 3D structureRetinoic acid receptor gammaP18911Mus musculusPredicted (SEA)
Prediction Confidence Score
0.391
Applicability Domain
0.434
Statistical Significance
1.40e-04
Supporting Reference Compounds
14
E-value
1.08989
Retinoic acid receptor beta structureClick to view 3D structureRetinoic acid receptor betaP22605Mus musculusPredicted (SEA)
Prediction Confidence Score
0.391
Applicability Domain
0.434
Statistical Significance
1.40e-04
Supporting Reference Compounds
14
E-value
1.08989
Retinoic acid receptor RXR-alpha structureClick to view 3D structureRetinoic acid receptor RXR-alphaP19793HumansPredicted (SEA)
Prediction Confidence Score
0.38
Applicability Domain
0.434
Statistical Significance
0.0015
Supporting Reference Compounds
82
E-value
11.5217
Retinoic acid receptor gamma structureClick to view 3D structureRetinoic acid receptor gammaP13631HumansPredicted (SEA)
Prediction Confidence Score
0.376
Applicability Domain
0.434
Statistical Significance
0.0012
Supporting Reference Compounds
52
E-value
9.18621
Retinoic acid receptor RXR-alpha structureClick to view 3D structureRetinoic acid receptor RXR-alphaP28700Mus musculusPredicted (SEA)
Prediction Confidence Score
0.356
Applicability Domain
0.434
Statistical Significance
2.90e-04
Supporting Reference Compounds
17
E-value
2.25763
Cellular retinoic acid-binding protein 1 structureClick to view 3D structureCellular retinoic acid-binding protein 1P62965Mus musculusPredicted (SEA)
Prediction Confidence Score
0.356
Applicability Domain
0.434
Statistical Significance
7.00e-05
Supporting Reference Compounds
7
E-value
0.544945
Click to view 3D structureCellular retinoic acid-binding protein 2P22935Mus musculusPredicted (SEA)
Prediction Confidence Score
0.356
Applicability Domain
0.434
Statistical Significance
7.00e-05
Supporting Reference Compounds
7
E-value
0.544945
Prosaposin structureClick to view 3D structureProsaposinP07602HumansPredicted (SEA)
Prediction Confidence Score
0.354
Applicability Domain
0.354
Statistical Significance
6.00e-05
Supporting Reference Compounds
1
E-value
0.467095
Retinoic acid receptor beta structureClick to view 3D structureRetinoic acid receptor betaP10826HumansPredicted (SEA)
Prediction Confidence Score
0.347
Applicability Domain
0.434
Statistical Significance
7.50e-04
Supporting Reference Compounds
47
E-value
5.83869
Retinoic acid receptor alpha structureClick to view 3D structureRetinoic acid receptor alphaP10276HumansPredicted (SEA)
Prediction Confidence Score
0.347
Applicability Domain
0.434
Statistical Significance
0.0015
Supporting Reference Compounds
53
E-value
11.7552
Click to view 3D structureCellular retinoic acid-binding protein 1P40220Gallus gallusPredicted (SEA)
Prediction Confidence Score
0.347
Applicability Domain
0.434
Statistical Significance
6.00e-05
Supporting Reference Compounds
5
E-value
0.467095
Retinoic acid receptor RXR-gamma structureClick to view 3D structureRetinoic acid receptor RXR-gammaP48443HumansPredicted (SEA)
Prediction Confidence Score
0.331
Applicability Domain
0.434
Statistical Significance
5.60e-04
Supporting Reference Compounds
31
E-value
4.35956
Amyloid-beta precursor protein structureClick to view 3D structureAmyloid-beta precursor proteinP05067HumansPredicted (SEA)
Prediction Confidence Score
0.326
Applicability Domain
0.451
Statistical Significance
0.0079
Supporting Reference Compounds
109
E-value
61.3452
Retinoic acid receptor RXR-beta structureClick to view 3D structureRetinoic acid receptor RXR-betaP28702HumansPredicted (SEA)
Prediction Confidence Score
0.319
Applicability Domain
0.434
Statistical Significance
6.80e-04
Supporting Reference Compounds
31
E-value
5.29375
Beta-lactoglobulin structureClick to view 3D structureBeta-lactoglobulinP02754Bos taurusPredicted (SEA)
Prediction Confidence Score
0.312
Applicability Domain
0.407
Statistical Significance
7.00e-05
Supporting Reference Compounds
2
E-value
0.544945
Alpha-synuclein structureClick to view 3D structureAlpha-synucleinP37840HumansPredicted (SEA)
Prediction Confidence Score
0.307
Applicability Domain
0.451
Statistical Significance
1.00e-03
Supporting Reference Compounds
38
E-value
7.78492
Click to view 3D structureRetinoic acid receptor RXR-gammaP28705Mus musculusPredicted (SEA)
Prediction Confidence Score
0.285
Applicability Domain
0.434
Statistical Significance
7.80e-04
Supporting Reference Compounds
20
E-value
6.07224
Click to view 3D structureSphingolipid delta(4)-desaturase DES1Q5XIF5Rattus norvegicusPredicted (SEA)
Prediction Confidence Score
0.279
Applicability Domain
0.413
Statistical Significance
4.00e-05
Supporting Reference Compounds
3
E-value
0.311397
Bile salt export pump structureClick to view 3D structureBile salt export pumpO95342HumansPredicted (SEA)
Prediction Confidence Score
0.274
Applicability Domain
0.489
Statistical Significance
0.0101
Supporting Reference Compounds
104
E-value
78.5499
Click to view 3D structureRetinoic acid receptor RXR-betaP28704Mus musculusPredicted (SEA)
Prediction Confidence Score
0.274
Applicability Domain
0.434
Statistical Significance
8.60e-04
Supporting Reference Compounds
19
E-value
6.69503
5-hydroxytryptamine receptor 2B structureClick to view 3D structure5-hydroxytryptamine receptor 2BP41595HumansPredicted (SEA)
Prediction Confidence Score
0.259
Applicability Domain
0.434
Statistical Significance
0.1738
Supporting Reference Compounds
686
E-value
1352.86
Adenosine receptor A3 structureClick to view 3D structureAdenosine receptor A3P0DMS8HumansPredicted (SEA)
Prediction Confidence Score
0.256
Applicability Domain
0.434
Statistical Significance
0.0976
Supporting Reference Compounds
391
E-value
759.653
Mitogen-activated protein kinase 1 structureClick to view 3D structureMitogen-activated protein kinase 1P28482HumansPredicted (SEA)
Prediction Confidence Score
0.25
Applicability Domain
0.434
Statistical Significance
0.3124
Supporting Reference Compounds
763
E-value
2432.09
Prostaglandin G/H synthase 2 structureClick to view 3D structureProstaglandin G/H synthase 2P35354HumansKnownNot Available
C-C motif chemokine 2 structureClick to view 3D structureC-C motif chemokine 2P13500HumansKnownNot Available
Catalase structureClick to view 3D structureCatalaseP04040HumansKnownNot Available
Heme oxygenase 1 structureClick to view 3D structureHeme oxygenase 1P09601HumansKnownNot Available
Concentrations
Not Available
External Links
DrugBank IDDB06543
HMDB IDHMDB0002204
FooDB IDFDB018640
Phenol Explorer IDNot Available
KNApSAcK IDC00000918
BiGG IDNot Available
BioCyc IDNot Available
METLIN ID3671
PDB IDNot Available
Wikipedia LinkAstaxanthin
Chemspider ID4444636
ChEBI ID40968
PubChem Compound ID5281224
Kegg Compound IDC08580
YMDB IDNot Available
ECMDB IDM2MDB005295
References
Synthesis ReferenceNot Available
MSDSNot Available
General ReferencesNot Available