CLAY, ATTAPULGITE (CED0007523)

Record Information

Version

1.0

Creation Date

2016-05-19 01:58:58 UTC

Update Date

2026-05-14 17:09:39 UTC

Accession Number

CHEM005181

Identification

Common Name

CLAY, ATTAPULGITE

Class

Small Molecule

Description

CLAY, ATTAPULGITE belongs to the post-transition metal hydroxides, a subclass of post-transition metal oxoanionic compounds within the inorganic compounds. This mixed metal/non-metal compound has the chemical formula Al2H45Mg2O15Si4. With an average molecular weight of 500.26 g/mol, CLAY, ATTAPULGITE is a heavy molecule. In industrial applications, the compound serves several roles, functioning as a thickening agent, a viscosity modifier, and a filler. Additionally, it is utilized as a flow promoter and as processing aids not otherwise specified. Beyond industrial use, it is recorded as being found in or released from healthcare, pharmaceuticals, and veterinary products, specifically as intestinal adsorbents. The recorded exposure route for this application is oral.

Contaminant Type

Not Available

Chemical Structure

MOL SDF PDB SMILES InChI

Synonyms

Value	Source
Dialumane tetradecahydric acid dimagnesium tetrasilane hydroxide	Generator

Chemical Formula

Al₂H₄₅Mg₂O₁₅Si₄

Average Molecular Mass

500.259 g/mol

Monoisotopic Mass

499.117 g/mol

CAS Registry Number

12174-11-7

IUPAC Name

dialumane tetradecahydrate dimagnesium tetrasilane hydroxide

Traditional Name

dialumane tetradecahydrate dimagnesium tetrasilane hydroxide

SMILES

O.O.O.O.O.O.O.O.O.O.O.O.O.O.[OH-].[Mg].[Mg].[Al].[Al].[SiH4].[SiH4].[SiH4].[SiH4]

InChI Identifier

InChI=1S/2Al.2Mg.15H2O.4H4Si/h;;;;15*1H2;4*1H4/p-1

InChI Key

NZGMGOQZZYLMJW-UHFFFAOYSA-M

Chemical Taxonomy

Description

Belongs to the class of inorganic compounds known as post-transition metal hydroxides. These are inorganic compounds in which the largest oxoanion is hydroxide, and in which the heaviest atom not in an oxoanion is a post-transition metal.

Kingdom

Inorganic compounds

Super Class

Mixed metal/non-metal compounds

Class

Post-transition metal oxoanionic compounds

Sub Class

Post-transition metal hydroxides

Direct Parent

Post-transition metal hydroxides

Alternative Parents

Substituents

Post-transition metal hydroxide
Inorganic hydride
Inorganic oxide
Inorganic salt
Inorganic metalloid salt

Molecular Framework

Not Available

External Descriptors

Not Available

Biological Properties

Status

Detected and Not Quantified

Origin

Not Available

Cellular Locations

Not Available

Biofluid Locations

Not Available

Tissue Locations

Not Available

Applications

Not Available

Biological Roles

Not Available

Chemical Roles

Not Available

Organoleptic Effects

Not Available

Physical Properties

State

Not Available

Appearance

Not Available

Experimental Properties

Property	Value
Melting Point	Not Available
Boiling Point	Not Available
Solubility	Not Available

Predicted Properties

Property	Value	Source
logP	1.45	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	0	ChemAxon
Hydrogen Donor Count	0	ChemAxon
Polar Surface Area	0 Å²	ChemAxon
Rotatable Bond Count	0	ChemAxon
Refractivity	0 m³·mol⁻¹	ChemAxon
Polarizability	1.78 Å³	ChemAxon
Number of Rings	0	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	No	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	Yes	ChemAxon
MDDR-like Rule	No	ChemAxon

Spectra

Spectrum Type	Description	Splash Key	Deposition Date	View
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-014i-0000090000-982cc96aef4a3a0f1a73	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-014i-0000090000-982cc96aef4a3a0f1a73	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-014i-0000090000-982cc96aef4a3a0f1a73	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-03di-0000090000-94871a4e5ba45d2d5ea5	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-03di-0000090000-94871a4e5ba45d2d5ea5	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-03di-0000090000-94871a4e5ba45d2d5ea5	Not Available	View Spectrum

Toxicity Profile

Mechanism of Toxicity

Not Available

Carcinogenicity (IARC Classification)

Not Available

Minimum Risk Level

Not Available

Symptoms

Not Available

Treatment

Not Available

Toxicity Values

Not Available

Health Effects

Health Effect	Relationship	Direction	Reference

Exposure Sources

Source ID	Source	Sector	Reference
255	Intestinal adsorbents	Healthcare, pharmaceuticals & veterinary products	Not Available

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this synthetic chemical

Targets

Structure	Protein	UniProt ID	Organism	Relationship	Details
Click to view 3D structure	D(3) dopamine receptor	P35462	Humans	Predicted (SEA)	7784.69
Click to view 3D structure	D(2) dopamine receptor	P14416	Humans	Predicted (SEA)	7784.69
Click to view 3D structure	5-hydroxytryptamine receptor 1A	P19327	Rattus norvegicus	Predicted (SEA)	7784.61
Click to view 3D structure	D(2) dopamine receptor	P61169	Rat	Predicted (SEA)	7784.61
Click to view 3D structure	5-hydroxytryptamine receptor 6	P50406	Humans	Predicted (SEA)	7784.69
Click to view 3D structure	5-hydroxytryptamine receptor 1A	P08908	Humans	Predicted (SEA)	7784.69
Click to view 3D structure	Carbonic anhydrase 1	P00915	Humans	Predicted (SEA)	7784.92
Click to view 3D structure	5-hydroxytryptamine receptor 2A	P28223	Humans	Predicted (SEA)	7784.69
Click to view 3D structure	5-hydroxytryptamine receptor 7	P32305	Rattus norvegicus	Predicted (SEA)	7784.53
Click to view 3D structure	5-hydroxytryptamine receptor 7	P34969	Humans	Predicted (SEA)	7784.69
Click to view 3D structure	D(4) dopamine receptor	P21917	Humans	Predicted (SEA)	7784.61
Click to view 3D structure	D(1A) dopamine receptor	P18901	Rattus norvegicus	Predicted (SEA)	7784.61
Click to view 3D structure	5-hydroxytryptamine receptor 1D	P28221	Humans	Predicted (SEA)	7784.69
Click to view 3D structure	Alpha-1B adrenergic receptor	P35368	Humans	Predicted (SEA)	7784.69
Click to view 3D structure	5-hydroxytryptamine receptor 2A	P14842	Rattus norvegicus	Predicted (SEA)	7784.61
Click to view 3D structure	5-hydroxytryptamine receptor 1B	P28564	Rattus norvegicus	Predicted (SEA)	7784.61
Click to view 3D structure	5-hydroxytryptamine receptor 2C	P28335	Humans	Predicted (SEA)	7784.69
Click to view 3D structure	5-hydroxytryptamine receptor 1B	P28222	Humans	Predicted (SEA)	7784.69
Click to view 3D structure	Alpha-1A adrenergic receptor	P43140	Rattus norvegicus	Predicted (SEA)	7784.61
Click to view 3D structure	5-hydroxytryptamine receptor 2B	P41595	Humans	Predicted (SEA)	7784.61
Click to view 3D structure	Glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase	Q9BHT9	Plasmodium berghei	Predicted (SEA)	7784.61
Click to view 3D structure	5-hydroxytryptamine receptor 4	Q13639	Humans	Predicted (SEA)	7784.61
Click to view 3D structure	5-hydroxytryptamine receptor 2C	P08909	Rat	Predicted (SEA)	7784.61
Click to view 3D structure	Sodium-dependent serotonin transporter	P31645	Humans	Predicted (SEA)	7784.69
Click to view 3D structure	Alpha-1A adrenergic receptor	P35348	Humans	Predicted (SEA)	7784.69