ETHYLENEDIAMINETETRAACETIC ACID DISODIUM SALT (CED0004366)

Record Information
Version1.0
Creation Date2016-05-19 02:04:04 UTC
Update Date2026-05-14 19:43:33 UTC
Accession NumberCHEM005586
Identification
Common NameETHYLENEDIAMINETETRAACETIC ACID DISODIUM SALT
ClassSmall Molecule
Description
ETHYLENEDIAMINETETRAACETIC ACID DISODIUM SALT is an organic compound with the formula C10H14N2Na2O8 and an average molecular weight of 336.21 g/mol. ETHYLENEDIAMINETETRAACETIC ACID DISODIUM SALT belongs to the tetracarboxylic acids and derivatives, a subclass of carboxylic acids and derivatives within the organic compounds. In industrial applications, the compound serves as a chelating agent, antioxidant, catalyst, fragrance, and as a flavouring and nutrient (PMC11040065). Biologically, it is used as an anticoagulant (PMC6055888). The substance is found in or released from 27 recorded sources. Within the category of electrical and electronic equipment, it is associated with electrodes, antennas, conductors or conductive bodies characterised by the conductive materials, electric switches, and electrically stimulated smoking devices, among 6 others. In household cleaning and consumer products, it appears in soap detergents, bleaching agents, perfumes within detergents and soaps, cigar cigarettes, and non electric simulated smoking devices, among 3 others. Its presence in food, food processing, and cookware includes food preservation, processing fish, the preparation of vinegar, the preparation of wine or sparkling wine, and fermentation processes for beer, among 1 other source. Additionally, it is found in building and construction materials such as stairs and ramps as well as fencing.
Contaminant TypeNot Available
Chemical Structure
Synonyms
ValueSource
(Ethylenedinitrilo)tetraacetic acid disodium saltChEBI
Disodium edetateChEBI
Disodium edetate (anh.)ChEBI
Disodium edetate (anhydrous)ChEBI
Disodium edtaChEBI
Disodium edta (anh.)ChEBI
Disodium edta (anhydrous)ChEBI
Edetate disodiumChEBI
Edetate disodium (anh.)ChEBI
Edetate disodium (anhydrous)ChEBI
Edetate disodium anhydrousChEBI
EDTA disodiumChEBI
EDTA disodium (anh.)ChEBI
EDTA disodium (anhydrous)ChEBI
EDTA disodium salt (anh.)ChEBI
Ethylenebis(iminodiacetic acid) disoidum saltChEBI
Ethylenediaminetetraacetic acid disodium saltChEBI
N,N'-1,2-ethanediylbis[N-(carboxymethyl)glycine], disodium saltChEBI
Na2-edtaChEBI
Na2h2EdtaChEBI
EndrateKegg
(Ethylenedinitrilo)tetraacetate disodium saltGenerator
Disodium edetic acidGenerator
Disodium edetic acid (anh.)Generator
Disodium edetic acid (anhydrous)Generator
Edetic acid disodiumGenerator
Edetic acid disodium (anh.)Generator
Edetic acid disodium (anhydrous)Generator
Edetic acid disodium anhydrousGenerator
Ethylenebis(iminodiacetate) disoidum saltGenerator
Ethylenediaminetetraacetate disodium saltGenerator
Endric acidGenerator
Acid, edeticMeSH
Acid, ethylenediaminetetraaceticMeSH
Acid, ethylenedinitrilotetraaceticMeSH
Calcitetracemate, disodiumMeSH
Calcium disodium edetateMeSH
Calcium disodium versenateMeSH
Calcium tetacineMeSH
Chelaton 3MeSH
Chromium edtaMeSH
Copper edtaMeSH
CoprinMeSH
Dicobalt edtaMeSH
Dinitrilotetraacetate, disodium ethyleneMeSH
Dinitrilotetraacetate, ethyleneMeSH
Disodium calcitetracemateMeSH
Disodium ethylene dinitrilotetraacetateMeSH
Disodium versenate, calciumMeSH
Distannous edtaMeSH
EDTAMeSH
EDTA, chromiumMeSH
EDTA, copperMeSH
EDTA, dicobaltMeSH
EDTA, disodiumMeSH
EDTA, distannousMeSH
EDTA, galliumMeSH
EDTA, magnesium disodiumMeSH
EDTA, potassiumMeSH
EDTA, stannousMeSH
EdathamilMeSH
Edetate disodium calciumMeSH
Edetate, calcium disodiumMeSH
EdetatesMeSH
Edetic acidMeSH
Edetic acid, calcium saltMeSH
Edetic acid, calcium, sodium saltMeSH
Edetic acid, chromium saltMeSH
Edetic acid, dipotassium saltMeSH
Edetic acid, disodium saltMeSH
Edetic acid, disodium salt, dihydrateMeSH
Edetic acid, disodium, magnesium saltMeSH
Edetic acid, disodium, monopotassium saltMeSH
Edetic acid, magnesium saltMeSH
Edetic acid, monopotassium saltMeSH
Edetic acid, monosodium saltMeSH
Edetic acid, potassium saltMeSH
Edetic acid, sodium saltMeSH
Ethylene dinitrilotetraacetateMeSH
Ethylene dinitrilotetraacetate, disodiumMeSH
Ethylenediaminetetraacetic acidMeSH
Ethylenedinitrilotetraacetic acidMeSH
Gallium edtaMeSH
Magnesium disodium edtaMeSH
N,N'-1,2-ethanediylbis(N-(carboxymethyl)glycine)MeSH
Potassium edtaMeSH
Stannous edtaMeSH
Tetacine, calciumMeSH
TetracemateMeSH
VersenateMeSH
Versenate, calcium disodiumMeSH
VerseneMeSH
Disodium ethylenediaminetetraacetic acidGenerator
Chemical FormulaC10H14N2Na2O8
Average Molecular Mass336.206 g/mol
Monoisotopic Mass336.055 g/mol
CAS Registry Number6381-92-6
IUPAC Namedisodium 2-({2-[(carboxylatomethyl)(carboxymethyl)amino]ethyl}(carboxymethyl)amino)acetate
Traditional Namedisodium 2-({2-[(carboxylatomethyl)(carboxymethyl)amino]ethyl}(carboxymethyl)amino)acetate
SMILES[Na+].[Na+].OC(=O)CN(CCN(CC(O)=O)CC([O-])=O)CC([O-])=O
InChI IdentifierInChI=1S/C10H16N2O8.2Na/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;/q;2*+1/p-2
InChI KeyZGTMUACCHSMWAC-UHFFFAOYSA-L
Chemical Taxonomy
Description Belongs to the class of organic compounds known as tetracarboxylic acids and derivatives. These are carboxylic acids containing exactly four carboxyl groups.
KingdomOrganic compounds
Super ClassOrganic acids and derivatives
ClassCarboxylic acids and derivatives
Sub ClassTetracarboxylic acids and derivatives
Direct ParentTetracarboxylic acids and derivatives
Alternative Parents
Substituents
  • Tetracarboxylic acid or derivatives
  • Alpha-amino acid
  • Alpha-amino acid or derivatives
  • Amino acid or derivatives
  • Carboxylic acid salt
  • Amino acid
  • Tertiary amine
  • Tertiary aliphatic amine
  • Carboxylic acid
  • Organic alkali metal salt
  • Organic sodium salt
  • Organic nitrogen compound
  • Hydrocarbon derivative
  • Organooxygen compound
  • Organonitrogen compound
  • Organic oxide
  • Carbonyl group
  • Organopnictogen compound
  • Amine
  • Organic oxygen compound
  • Organic zwitterion
  • Organic salt
  • Aliphatic acyclic compound
Molecular FrameworkAliphatic acyclic compounds
External Descriptors
Biological Properties
StatusDetected and Not Quantified
OriginNot Available
Cellular LocationsNot Available
Biofluid LocationsNot Available
Tissue LocationsNot Available
ApplicationsNot Available
Biological Roles
Chemical RolesNot Available
Organoleptic EffectsNot Available
Physical Properties
StateNot Available
AppearanceNot Available
Experimental Properties
PropertyValue
Melting PointNot Available
Boiling PointNot Available
SolubilityNot Available
Predicted Properties
PropertyValueSource
Water Solubility72 g/LALOGPS
logP-1ALOGPS
logP-5.2ChemAxon
logS-0.67ALOGPS
pKa (Strongest Acidic)1.49ChemAxon
pKa (Strongest Basic)8.13ChemAxon
Physiological Charge-3ChemAxon
Hydrogen Acceptor Count10ChemAxon
Hydrogen Donor Count2ChemAxon
Polar Surface Area161.34 ŲChemAxon
Rotatable Bond Count11ChemAxon
Refractivity84.02 m³·mol⁻¹ChemAxon
Polarizability25.43 ųChemAxon
Number of Rings0ChemAxon
BioavailabilityYesChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon
Spectra
Spectra
Spectrum TypeDescriptionSplash KeyDeposition DateView
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-00kr-0196000000-aef580df1e43f7a2c144Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-01q9-0941000000-bf9da2d35874c68ef764Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-01wk-1920000000-8e74b62fc3c2a5cfbb7dNot AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-000i-0009000000-c0418315e94d6c9924a9Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-000i-0009000000-c0418315e94d6c9924a9Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-000i-0009000000-c0418315e94d6c9924a9Not AvailableView Spectrum
Toxicity Profile
Mechanism of ToxicityNot Available
Carcinogenicity (IARC Classification)Not Available
Minimum Risk LevelNot Available
SymptomsNot Available
TreatmentNot Available
Toxicity Values
Toxicity ValueUnitValue RangeOrganismDose DescriptorRoute of ExposurePredicted or ExperimentalReference
3166.0Log mg/kg[1800:5600]RatLD50oralpredictedNot Available
Health Effects
Health EffectRelationshipDirectionReference
Exposure Sources
Source IDSourceSectorReference
10InsecticidesAgriculture & land managementNot Available
233BrushesPersonal care & cosmeticsNot Available
496FencingBuilding & ConstructionNot Available
500Stairs And RampsBuilding & ConstructionNot Available
506AntennasElectrical & Electronic EquipmentNot Available
511Conductors Or Conductive Bodies Characterised By The Conductive MaterialsElectrical & Electronic EquipmentNot Available
517Electric SwitchesElectrical & Electronic EquipmentNot Available
518Electrically Stimulated Smoking DevicesElectrical & Electronic EquipmentNot Available
519ElectrodesElectrical & Electronic EquipmentNot Available
521Fixed Capacitors And Their ManufactureElectrical & Electronic EquipmentNot Available
524Hybrid CapacitorsElectrical & Electronic EquipmentNot Available
527MagnetsElectrical & Electronic EquipmentNot Available
537Television SystemsElectrical & Electronic EquipmentNot Available
538Thin Magnetic FilmsElectrical & Electronic EquipmentNot Available
540X Ray TubesElectrical & Electronic EquipmentNot Available
544Fermentation Processes For BeerFood, food processing & cookwareNot Available
545Food PreservationFood, food processing & cookwareNot Available
548Preparation Of VinegarFood, food processing & cookwareNot Available
549Preparation Of Wine Or Sparkling WineFood, food processing & cookwareNot Available
551Processing FishFood, food processing & cookwareNot Available
552Processing MeatsFood, food processing & cookwareNot Available
555Bleaching AgentsHousehold cleaning & consumer productsNot Available
556Cigar CigarettesHousehold cleaning & consumer productsNot Available
559Non Electric Simulated Smoking DevicesHousehold cleaning & consumer productsNot Available
561Perfumes Within Detergents And SoapsHousehold cleaning & consumer productsNot Available
563Soap DetergentsHousehold cleaning & consumer productsNot Available
564Soap DispensersHousehold cleaning & consumer productsNot Available
566Tobacco PipesHousehold cleaning & consumer productsNot Available
569Tobacco Smoke FiltersHousehold cleaning & consumer productsNot Available
579Manufacture Of Iron Or SteelIndustrial manufacturing & chemical processingNot Available
580Manufacture Preparation Of Tobacco ProductsIndustrial manufacturing & chemical processingNot Available
581Paper Making MachinesIndustrial manufacturing & chemical processingNot Available
596AcaricidesAgriculture & land managementNot Available
597ChemosterilantsAgriculture & land managementNot Available
600Herbicides And AlgicidesAgriculture & land managementNot Available
602MolluscicidesAgriculture & land managementNot Available
603NematocidesAgriculture & land managementNot Available
604Pest AttractantsAgriculture & land managementNot Available
605Pest RepellantsAgriculture & land managementNot Available
606Plant Growth RegulatorsAgriculture & land managementNot Available
607Rodenticides(1)Agriculture & land managementNot Available
608RodenticidesAgriculture & land managementNot Available
609AftershavePersonal care & cosmeticsNot Available
610Aftersun ProductsPersonal care & cosmeticsNot Available
611Anti Perspirants Or Body DeoderantsPersonal care & cosmeticsNot Available
612Body Washing Or Cleaning ImplementsPersonal care & cosmeticsNot Available
613DepilatoriesPersonal care & cosmeticsNot Available
614Essential Oils Or PerfumesPersonal care & cosmeticsNot Available
615Eye Makeup ProductsPersonal care & cosmeticsNot Available
616Face Mask CosmeticsPersonal care & cosmeticsNot Available
617Lip Care ProductsPersonal care & cosmeticsNot Available
618Lip Makeup ProductsPersonal care & cosmeticsNot Available
619Manicure PedicurePersonal care & cosmeticsNot Available
630ToysRecreation & sports surfacesNot Available
632ApparelTextiles, leather & furnishingsNot Available
638Decorating TextilesTextiles, leather & furnishingsNot Available
639Degreasing LeatherTextiles, leather & furnishingsNot Available
640Embroidering And TuftingTextiles, leather & furnishingsNot Available
642FootwearTextiles, leather & furnishingsNot Available
643HeadwearTextiles, leather & furnishingsNot Available
647Multicolour DyeingTextiles, leather & furnishingsNot Available
650Purses Luggage Hand BagsTextiles, leather & furnishingsNot Available
655Slide FastenersTextiles, leather & furnishingsNot Available
657Surface Finishing Of LeatherTextiles, leather & furnishingsNot Available
659Transfer PrintingTextiles, leather & furnishingsNot Available
662Yarns Or ThreadsTextiles, leather & furnishingsNot Available
Pathways
2 pathways
Targets
StructureProteinUniProt IDOrganismRelationshipDetails
Click to view 3D structureBeta-lactamase VIM-1Q9XAY4Pseudomonas aeruginosaPredicted (SEA)0.0778492
Click to view 3D structureCarbonic anhydrase 4Q95323Bos taurusPredicted (SEA)24.6004
Carbonic anhydrase 2 structureClick to view 3D structureCarbonic anhydrase 2P00918HumansPredicted (SEA)99.647
Carbonic anhydrase 1 structureClick to view 3D structureCarbonic anhydrase 1P00915HumansPredicted (SEA)146.123
Click to view 3D structureSodium- and chloride-dependent creatine transporter 1P48029HumansPredicted (SEA)0.467095
Carbonic anhydrase 4 structureClick to view 3D structureCarbonic anhydrase 4P22748HumansPredicted (SEA)159.902
Carbonic anhydrase 9 structureClick to view 3D structureCarbonic anhydrase 9Q16790HumansPredicted (SEA)753.892
Carbonic anhydrase 12 structureClick to view 3D structureCarbonic anhydrase 12O43570HumansPredicted (SEA)685.385
Metallo-beta-lactamase type 2 structureClick to view 3D structureMetallo-beta-lactamase type 2C7C422Klebsiella pneumoniaePredicted (SEA)14.1686
Click to view 3D structure3-isopropylmalate dehydrogenaseQ5SIY4Thermus thermophilusPredicted (SEA)0.0778492
Amyloid-beta precursor protein structureClick to view 3D structureAmyloid-beta precursor proteinP05067HumansPredicted (SEA)493.798
Egl nine homolog 1 structureClick to view 3D structureEgl nine homolog 1Q9GZT9HumansPredicted (SEA)458.61
Lysine-specific demethylase 2A structureClick to view 3D structureLysine-specific demethylase 2AQ9Y2K7HumansPredicted (SEA)317.236
Histone lysine demethylase PHF8 structureClick to view 3D structureHistone lysine demethylase PHF8Q9UPP1HumansPredicted (SEA)16.0369
Click to view 3D structureSodium- and chloride-dependent GABA transporter 2P31646Rattus norvegicusPredicted (SEA)10.7432
Matrix metalloproteinase-14 structureClick to view 3D structureMatrix metalloproteinase-14P50281HumansPredicted (SEA)3739.8
72 kDa type IV collagenase structureClick to view 3D structure72 kDa type IV collagenaseP08253HumansPredicted (SEA)5131.59
Neutrophil collagenase structureClick to view 3D structureNeutrophil collagenaseP22894HumansPredicted (SEA)3329.69
Click to view 3D structureOrganic anion transporter 3O88909Mus musculusPredicted (SEA)180.766
Olfactory receptor 51E2 structureClick to view 3D structureOlfactory receptor 51E2Q9H255HumansPredicted (SEA)15.1806
Interstitial collagenase structureClick to view 3D structureInterstitial collagenaseP03956HumansPredicted (SEA)4775.66
Matrix metalloproteinase-9 structureClick to view 3D structureMatrix metalloproteinase-9P14780HumansPredicted (SEA)4998.93
Click to view 3D structureFree fatty acid receptor 3B2GV46Rattus norvegicusPredicted (SEA)1.94623
Click to view 3D structureSodium- and chloride-dependent betaine transporterP48065HumansPredicted (SEA)14.0129
Collagenase 3 structureClick to view 3D structureCollagenase 3P45452HumansPredicted (SEA)5676.14
Concentrations
Not Available
External Links
DrugBank IDDBSALT000838
HMDB IDHMDB0303556
FooDB IDFDB015445
Phenol Explorer IDNot Available
KNApSAcK IDNot Available
BiGG IDNot Available
BioCyc IDNot Available
METLIN IDNot Available
PDB IDNot Available
Wikipedia LinkNot Available
Chemspider ID8429
ChEBI ID64734
PubChem Compound ID8759
Kegg Compound IDNot Available
YMDB IDNot Available
ECMDB IDNot Available
References
Synthesis ReferenceNot Available
MSDSNot Available
General References