MAGNESIUM HYDROXIDE (CED0001644)

Record Information

Version

1.0

Creation Date

2016-05-19 02:12:47 UTC

Update Date

2026-05-14 19:02:34 UTC

Accession Number

CHEM006357

Identification

Common Name

MAGNESIUM HYDROXIDE

Class

Small Molecule

Description

MAGNESIUM HYDROXIDE belongs to the alkaline earth metal hydroxides, a subclass of alkaline earth metal oxoanionic compounds within the inorganic compounds. This compound has the chemical formula H2MgO2 and an average molecular weight of 58.32 g/mol. It is further classified as a mixed metal/non-metal compound. In industrial contexts, magnesium hydroxide serves a wide variety of roles and uses. It is employed as a pH regulating agent, absorbent, flame retardant, binder, and filler. Additionally, it functions as a conductive agent, drier, dye, and flavouring and nutrient, as well as serving as processing aids not otherwise specified. The compound is found in or released from eleven recorded sources. Within the building and construction sector, it is present in ceilings, fencing, floors, roofs, stairs and ramps, and three other sources. In the realm of healthcare, pharmaceuticals, and veterinary products, it is used in urologicals and drugs for acid related disorders. It is also found in antennas within electrical and electronic equipment. Recorded exposure routes for the substance include oral and topical administration.

Contaminant Type

Not Available

Chemical Structure

MOL SDF PDB SMILES InChI

Synonyms

Value	Source
Magnesium hydrate	ChEBI
Magnesiumhydroxid	ChEBI
MG(OH)2	ChEBI
Milk OF magnesia	ChEBI
Milmag	Kegg
Mint-O-mag	Kegg
Magnesium hydric acid	Generator

Chemical Formula

H₂MgO₂

Average Molecular Mass

58.320 g/mol

Monoisotopic Mass

57.991 g/mol

CAS Registry Number

1309-42-8

IUPAC Name

magnesium(2+) ion dihydroxide

Traditional Name

magnesium(2+) ion dihydroxide

SMILES

[OH-].[OH-].[Mg++]

InChI Identifier

InChI=1S/Mg.2H2O/h;2*1H2/q+2;;/p-2

InChI Key

VTHJTEIRLNZDEV-UHFFFAOYSA-L

Chemical Taxonomy

Description

Belongs to the class of inorganic compounds known as alkaline earth metal hydroxides. These are inorganic compounds in which the largest oxoanion is hydroxide, and in which the heaviest atom not in an oxoanion is an alkaline earth metal.

Kingdom

Inorganic compounds

Super Class

Mixed metal/non-metal compounds

Class

Alkaline earth metal oxoanionic compounds

Sub Class

Alkaline earth metal hydroxides

Direct Parent

Alkaline earth metal hydroxides

Alternative Parents

Substituents

Alkaline earth metal hydroxide
Inorganic hydride
Inorganic oxide
Inorganic salt

Molecular Framework

Not Available

External Descriptors

magnesium hydroxide (CHEBI:6637 )

Biological Properties

Status

Detected and Not Quantified

Origin

Not Available

Cellular Locations

Not Available

Biofluid Locations

Not Available

Tissue Locations

Not Available

Applications

Not Available

Biological Roles

Not Available

Chemical Roles

Not Available

Organoleptic Effects

Not Available

Physical Properties

State

Not Available

Appearance

Not Available

Experimental Properties

Property	Value
Melting Point	Not Available
Boiling Point	Not Available
Solubility	Not Available

Predicted Properties

Property	Value	Source
logP	-0.57	ChemAxon
pKa (Strongest Acidic)	15.7	ChemAxon
pKa (Strongest Basic)	-1.8	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	0	ChemAxon
Hydrogen Donor Count	0	ChemAxon
Polar Surface Area	0 Å²	ChemAxon
Rotatable Bond Count	0	ChemAxon
Refractivity	0 m³·mol⁻¹	ChemAxon
Polarizability	1.78 Å³	ChemAxon
Number of Rings	0	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	Yes	ChemAxon
MDDR-like Rule	No	ChemAxon

Spectra

Not Available

Toxicity Profile

Mechanism of Toxicity

Not Available

Carcinogenicity (IARC Classification)

Not Available

Minimum Risk Level

Not Available

Symptoms

Not Available

Treatment

Not Available

Toxicity Values

Not Available

Health Effects

Health Effect	Relationship	Direction	Reference

Exposure Sources

Source ID	Source	Sector	Reference
242	Drugs for acid related disorders	Healthcare, pharmaceuticals & veterinary products	Not Available
326	Urologicals	Healthcare, pharmaceuticals & veterinary products	Not Available
495	Ceilings	Building & Construction	Not Available
496	Fencing	Building & Construction	Not Available
497	Floors	Building & Construction	Not Available
499	Roofs	Building & Construction	Not Available
500	Stairs And Ramps	Building & Construction	Not Available
501	Sunshades Awnings Or Outside Screens	Building & Construction	Not Available
502	Sunshades Awnings Or Outside Screens	Building & Construction	Not Available
503	Tents Or Canopies	Building & Construction	Not Available
506	Antennas	Electrical & Electronic Equipment	Not Available

Pathways

1 pathway

Magnesium hydroxide Drug Metabolism Action Pathway

Targets

Structure	Protein	UniProt ID	Organism	Relationship	Details
Click to view 3D structure	Acetylcholinesterase	P07140	Drosophila melanogaster	Predicted (SEA)	7593.72
Click to view 3D structure	Carbonic anhydrase 2	P00918	Humans	Predicted (SEA)	7784.92
Click to view 3D structure	Carbonic anhydrase 1	P00915	Humans	Predicted (SEA)	7784.92
Click to view 3D structure	Carbonic anhydrase 9	Q16790	Humans	Predicted (SEA)	7785.0
Click to view 3D structure	Carbonic anhydrase 5A, mitochondrial	P35218	Humans	Predicted (SEA)	7784.84
Click to view 3D structure	Sodium-dependent noradrenaline transporter	P23975	Humans	Predicted (SEA)	7784.92
Click to view 3D structure	Muscarinic acetylcholine receptor M2	P08172	Humans	Predicted (SEA)	7785.0
Click to view 3D structure	Muscarinic acetylcholine receptor M4	P08173	Humans	Predicted (SEA)	7784.92
Click to view 3D structure	Histamine H1 receptor	P35367	Humans	Predicted (SEA)	7784.84
Click to view 3D structure	Alpha-2A adrenergic receptor	P08913	Humans	Predicted (SEA)	7784.92
Click to view 3D structure	Cytochrome P450 2C19	P33261	Humans	Predicted (SEA)	7784.92
Click to view 3D structure	Cytochrome P450 2C9	P11712	Humans	Predicted (SEA)	7784.92
Click to view 3D structure	D(1A) dopamine receptor	P21728	Humans	Predicted (SEA)	7784.84
Click to view 3D structure	Cytochrome P450 1A2	P05177	Humans	Predicted (SEA)	7784.92
Click to view 3D structure	Cytochrome P450 3A4	P08684	Humans	Predicted (SEA)	7784.92
Click to view 3D structure	Streptokinase A	P10520	Streptococcus pyogenes serotype M1	Predicted (SEA)	7785.0
Click to view 3D structure	Receptor-type tyrosine-protein kinase FLT3	P36888	Humans	Predicted (SEA)	7784.84
Click to view 3D structure	Alpha-2B adrenergic receptor	P18089	Humans	Predicted (SEA)	7784.92
Click to view 3D structure	5-hydroxytryptamine receptor 2A	P28223	Humans	Predicted (SEA)	7784.92
Click to view 3D structure	5-hydroxytryptamine receptor 2C	P28335	Humans	Predicted (SEA)	7784.92
Click to view 3D structure	Induced myeloid leukemia cell differentiation protein Mcl-1	Q07820	Humans	Predicted (SEA)	7784.92
Click to view 3D structure	Stimulator of interferon genes protein	F1M391	Rattus norvegicus	Predicted (SEA)	7783.91
Click to view 3D structure	D(3) dopamine receptor	P35462	Humans	Predicted (SEA)	7784.92
Click to view 3D structure	Muscarinic acetylcholine receptor M5	P08912	Humans	Predicted (SEA)	7785.0
Click to view 3D structure	Adenosine receptor A3	P0DMS8	Humans	Predicted (SEA)	7784.92