TOMATO LYCOPENE (CED0002984)

Record Information
Version1.0
Creation Date2016-05-19 02:29:13 UTC
Update Date2026-05-14 19:07:59 UTC
SynCED IDCED0002984
Secondary Accession Numbers
  • CHEM007698
Identification
Common NameTOMATO LYCOPENE
ClassSmall Molecule
Description
TOMATO LYCOPENE belongs to the tetraterpenoids, a subclass of prenol lipids within the organic compounds. With an average molecular weight of 536.89 g/mol, TOMATO LYCOPENE is a heavy molecule. It has the formula C40H56. Industrially, the compound is used as a dye, a food additive (PMC9818577 ), and as a flavouring and nutrient. It serves as an antioxidant in both biological and industrial contexts (PMC11125366 , PMC11765362 ) and acts as a biological inhibitor (PMC3257702 ). Environmentally, it is classified as a nutrient (PMC9818577 ). The compound is found in 19 recorded sources, including food processing and cookware, household cleaning and consumer products, electrical and electronic equipment, and building and construction materials. Health effects associated with TOMATO LYCOPENE include a decrease in cancer (PMC10220911 , PMC3257702 ), breast cancer (PMC8869647 ), lung cancer (PMC5000748 ), squamous cell carcinoma (PMC5000748 ), atherosclerosis (PMC9818577 ), ischemic stroke (PMC9075393 ), and prostate cancer (PMC9988266 ), as well as an inverse relationship with prostate cancer (PMC3823537 ). It is also associated with periodontal disease (PMC12924582 ). The compound is used as a treatment for male infertility (PMC9005387 ), ovarian cancer (PMC12021792 ), and prostate cancer (PMC11306087 ). Therapeutic effects have been noted for inflammation (PMC13211753 ), osteoporosis (PMC11306087 ), renal fibrosis (PMC12287420 ), diabetic retinopathy (PMC5793074 ), glioblastoma (PMC12466395 ), blood pressure (PMC8869647 ), myocardial infarction (PMC8869647 ), male infertility (PMC12957189 ), atherosclerosis (PMC10334012 ), cancer (PMC10334012 , PMC11306087 ), and prostate cancer (PMC12924582 , PMC3823537 ) and breast cancer (PMC11306087 , PMC9818577 ). Additionally, blood levels of the compound are decreased in cases of diabetes mellitus (PMC5793074 ).
Contaminant TypeNot Available
Chemical Structure
SynonymsNot Available
Chemical FormulaC40H56
Average Molecular Mass536.888 g/mol
Monoisotopic Mass536.438 g/mol
CAS Registry Number502-65-8
IUPAC Name(6E,8E,10E,12E,14Z,16Z,18E,20E,22E,24E,26E)-2,6,10,14,19,23,27,31-octamethyldotriaconta-2,6,8,10,12,14,16,18,20,22,24,26,30-tridecaene
Traditional Namecis-y,y-carotene
SMILESCC(C)=CCC\C(C)=C\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C=C(/C)CCC=C(C)C
InChI IdentifierInChI=1S/C40H56/c1-33(2)19-13-23-37(7)27-17-31-39(9)29-15-25-35(5)21-11-12-22-36(6)26-16-30-40(10)32-18-28-38(8)24-14-20-34(3)4/h11-12,15-22,25-32H,13-14,23-24H2,1-10H3/b12-11+,25-15+,26-16+,31-17+,32-18+,35-21+,36-22+,37-27+,38-28+,39-29+,40-30+
InChI KeyOAIJSZIZWZSQBC-GYZMGTAESA-N
Chemical Taxonomy
Description Belongs to the class of organic compounds known as carotenes. These are a type of unsaturated hydrocarbons containing eight consecutive isoprene units. They are characterized by the presence of two end-groups (mostly cyclohexene rings, but also cyclopentene rings or acyclic groups) linked by a long branched alkyl chain. Carotenes belonging form a subgroup of the carotenoids family.
KingdomOrganic compounds
Super ClassLipids and lipid-like molecules
ClassPrenol lipids
Sub ClassTetraterpenoids
Direct ParentCarotenes
Alternative Parents
Substituents
  • Carotene
  • Branched unsaturated hydrocarbon
  • Unsaturated aliphatic hydrocarbon
  • Unsaturated hydrocarbon
  • Olefin
  • Acyclic olefin
  • Hydrocarbon
  • Aliphatic acyclic compound
Molecular FrameworkAliphatic acyclic compounds
External DescriptorsNot Available
Biological Properties
StatusDetected and Not Quantified
OriginNot Available
Cellular LocationsNot Available
Biofluid LocationsNot Available
Tissue LocationsNot Available
ApplicationsNot Available
Biological Roles
Chemical RolesNot Available
Organoleptic Effects
  • dark colour ?
  • red colour ?
  • brown colour ?
  • orange colour ?
  • bright red colour ?
  • pink colour ?
  • deep red colour ?
  • red-orange colour ?
  • browning colour ?
  • red pigment colour ?
  • color fading colour ?
  • pink-orange colour ?
Physical Properties
StateNot Available
AppearanceNot Available
Experimental Properties
PropertyValue
Melting PointNot Available
Boiling PointNot Available
SolubilityNot Available
Predicted Properties
PropertyValueSource
Water Solubility0.0004 g/LALOGPS
logP9.16ALOGPS
logP11.93ChemAxon
logS-6.1ALOGPS
Physiological Charge0ChemAxon
Hydrogen Acceptor Count0ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area0 ŲChemAxon
Rotatable Bond Count16ChemAxon
Refractivity197.81 m³·mol⁻¹ChemAxon
Polarizability72.51 ųChemAxon
Number of Rings0ChemAxon
BioavailabilityNoChemAxon
Rule of FiveNoChemAxon
Ghose FilterNoChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon
Spectra
Spectra
Spectrum TypeDescriptionSplash KeyDeposition DateView
Predicted GC-MSPredicted GC-MS Spectrumsplash10-01b9-9111850000-7f5ee1d2f1f4dd233963Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0600-0951110000-51753e8053443b533c78Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-052r-0930010000-1432649abfd5fa58010eNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0600-0951110000-2db714bdbf8cb6620f55Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-052r-0930010000-7441e95c28b443b57134Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0600-0951110000-433c80c51edf87449345Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-052r-0930010000-79e6fe700d71dae15c5eNot AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-000i-0333490000-4e9a5975acd39d46ed6fNot AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-0012-1968510000-01d32351dab7917ce5d2Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-0159-4569500000-a5b112a0bf1e360b2480Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-000i-0000090000-77adf3223ff2af4c4c1aNot AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-000i-0000090000-0b5e06bca49e37a860efNot AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-014i-1859480000-4c571e364bf31d6a314eNot AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-000i-2235970000-73fc43e90358e2cae371Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-0fc1-2011900000-667641d02a3eee5d267dNot AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-0wb9-1223900000-52a07bb8af9e23809e6eNot AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-000i-0100090000-4ab68b33d589aeb3b2ddNot AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-000i-0926580000-889c9c655f28c8c703c8Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-0gb9-0503910000-a80f0ec28aa2775d93e0Not AvailableView Spectrum
Toxicity Profile
Toxicity Values
Toxicity ValueOrganismDose DescriptorRoute of ExposurePredicted or ExperimentalToxicity RatingReference
6067.0 Log mg/kg [3400:11000]RatLD50oralpredictedNot AvailableNot Available
1.0 mg/kg-day RatNOELoralexperimentalNot AvailableECOTOX - EPA ORD
Toxicity / Toxin ClassNot Available
Mechanism of ToxicityNot Available
Carcinogenicity (IARC Classification)Not Available
Minimum Risk LevelNot Available
SymptomsNot Available
TreatmentNot Available
Health Effects
Health EffectRelationshipDirectionDescriptionReference
lung cancerAssociated With?decreaseA respiratory system cancer that is located in the lung. (DO)PMC5000748 , PMC6268471
lung cancerAssociated With?Not AvailableA respiratory system cancer that is located in the lung. (DO)PMC4560207
lung cancerHas Therapeutic Effect OnNot AvailableA respiratory system cancer that is located in the lung. (DO)PMC9885113
lung cancerDecreased in Blood InNot AvailableA respiratory system cancer that is located in the lung. (DO)PMC5930792
hypertensionAssociated With?decreaseA disorder characterized by a pathological increase in blood pressure; a repeatedly elevation in the blood pressure exceeding 140 over 90 mm Hg. (NCI CTCAE)PMC11357572
blood pressureHas Therapeutic Effect OnNot AvailableNot AvailablePMC8869647
inflammationHas Therapeutic Effect OnNot AvailableNot AvailablePMC13211753 , PMC8773188
inflammationDecreased in Blood InNot AvailableNot AvailablePMC8911995
cancerAssociated With?decreaseCancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. Possible signs and symptoms include a lump, abnormal bleeding, prolonged cough, unexplained weight loss, and a change in bowel movements. There are over 100 types of cancers affect humans. The risk of developing certain cancers can be reduced by not smoking, maintaining a healthy weight, not drinking too much alcohol, eating plenty of vegetables, fruits and whole grains, vaccination against certain infectious diseases, not eating too much processed and red meat and avoiding too much sunlight exposure. Cancer is often treated with some combination of radiation therapy, surgery, chemotherapy and targeted therapy. The majority of cancers, some 90–95% of cases, are due to genetic mutations from environmental and lifestyle factors. The remaining 5–10% are due to inherited genetics.PMC10220911 , PMC3257702
cancerHas Therapeutic Effect OnNot AvailableCancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. Possible signs and symptoms include a lump, abnormal bleeding, prolonged cough, unexplained weight loss, and a change in bowel movements. There are over 100 types of cancers affect humans. The risk of developing certain cancers can be reduced by not smoking, maintaining a healthy weight, not drinking too much alcohol, eating plenty of vegetables, fruits and whole grains, vaccination against certain infectious diseases, not eating too much processed and red meat and avoiding too much sunlight exposure. Cancer is often treated with some combination of radiation therapy, surgery, chemotherapy and targeted therapy. The majority of cancers, some 90–95% of cases, are due to genetic mutations from environmental and lifestyle factors. The remaining 5–10% are due to inherited genetics.PMC10334012 , PMC11306087
cancerAssociated With?Not AvailableCancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. Possible signs and symptoms include a lump, abnormal bleeding, prolonged cough, unexplained weight loss, and a change in bowel movements. There are over 100 types of cancers affect humans. The risk of developing certain cancers can be reduced by not smoking, maintaining a healthy weight, not drinking too much alcohol, eating plenty of vegetables, fruits and whole grains, vaccination against certain infectious diseases, not eating too much processed and red meat and avoiding too much sunlight exposure. Cancer is often treated with some combination of radiation therapy, surgery, chemotherapy and targeted therapy. The majority of cancers, some 90–95% of cases, are due to genetic mutations from environmental and lifestyle factors. The remaining 5–10% are due to inherited genetics.PMC5666732 , PMC10220911
cancerAssociated With?inverseCancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. Possible signs and symptoms include a lump, abnormal bleeding, prolonged cough, unexplained weight loss, and a change in bowel movements. There are over 100 types of cancers affect humans. The risk of developing certain cancers can be reduced by not smoking, maintaining a healthy weight, not drinking too much alcohol, eating plenty of vegetables, fruits and whole grains, vaccination against certain infectious diseases, not eating too much processed and red meat and avoiding too much sunlight exposure. Cancer is often treated with some combination of radiation therapy, surgery, chemotherapy and targeted therapy. The majority of cancers, some 90–95% of cases, are due to genetic mutations from environmental and lifestyle factors. The remaining 5–10% are due to inherited genetics.PMC8434243
cancerNot AvailableNot AvailableCancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. Possible signs and symptoms include a lump, abnormal bleeding, prolonged cough, unexplained weight loss, and a change in bowel movements. There are over 100 types of cancers affect humans. The risk of developing certain cancers can be reduced by not smoking, maintaining a healthy weight, not drinking too much alcohol, eating plenty of vegetables, fruits and whole grains, vaccination against certain infectious diseases, not eating too much processed and red meat and avoiding too much sunlight exposure. Cancer is often treated with some combination of radiation therapy, surgery, chemotherapy and targeted therapy. The majority of cancers, some 90–95% of cases, are due to genetic mutations from environmental and lifestyle factors. The remaining 5–10% are due to inherited genetics.PMC5856442 , PMC9187586
breast cancerAssociated With?decreaseA breast cancer that has material basis in abnormally proliferating cells derives from epithelial cells. (DO)PMC8869647 , PMC3224257
breast cancerHas Therapeutic Effect OnNot AvailableA breast cancer that has material basis in abnormally proliferating cells derives from epithelial cells. (DO)PMC11306087 , PMC9818577
breast cancerAssociated With?Not AvailableA breast cancer that has material basis in abnormally proliferating cells derives from epithelial cells. (DO)PMC10187563
breast cancerAssociated With?inverseA breast cancer that has material basis in abnormally proliferating cells derives from epithelial cells. (DO)PMC80172
multiple sclerosisHas Therapeutic Effect OnNot AvailableA demyelinating disease that involves damage to the fatty myelin sheaths around the axons of the brain and spinal cord resulting in demyelination and scarring. (DO)PMC7824569
type 2 diabetes mellitusHas Therapeutic Effect OnNot AvailableNot AvailablePMC13192163
osteoporosisHas Therapeutic Effect OnNot AvailableA disorder characterized by reduced bone mass, with a decrease in cortical thickness and in the number and size of the trabeculae of cancellous bone (but normal chemical composition), resulting in increased fracture incidence. (NCI CTCAE)PMC11306087 , PMC7022261
osteoporosisAssociated With?decreaseA disorder characterized by reduced bone mass, with a decrease in cortical thickness and in the number and size of the trabeculae of cancellous bone (but normal chemical composition), resulting in increased fracture incidence. (NCI CTCAE)PMC8003428
osteoporosisNot AvailableNot AvailableA disorder characterized by reduced bone mass, with a decrease in cortical thickness and in the number and size of the trabeculae of cancellous bone (but normal chemical composition), resulting in increased fracture incidence. (NCI CTCAE)PMC8003428
diabetes mellitusDecreased in Blood IndecreaseA glucose metabolism disease characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both. (DO)PMC5793074
ischemic strokeAssociated With?decreaseNot AvailablePMC9075393
strokeAssociated With?decreaseNot AvailablePMC10525378 , PMC2464768
strokeAssociated With?increaseNot AvailablePMC11357572
Prostate cancerAssociated With?decreaseA male reproductive organ cancer that is located in the prostate. (DO)PMC9988266 , PMC3823537
Prostate cancerHas Therapeutic Effect OnNot AvailableA male reproductive organ cancer that is located in the prostate. (DO)PMC12924582 , PMC3823537
Prostate cancerAssociated With?inverseA male reproductive organ cancer that is located in the prostate. (DO)PMC3823537 , PMC11303474
Prostate cancerNot AvailableNot AvailableA male reproductive organ cancer that is located in the prostate. (DO)PMC11306087 , PMC10777738
Prostate cancerAssociated With?Not AvailableA male reproductive organ cancer that is located in the prostate. (DO)PMC10220911 , PMC12369773
necrosisHas Therapeutic Effect OnNot AvailableA disorder characterized as a form of cell injury which results in the premature death of cells in living tissue by autolysis.PMC13237055
colon cancerHas Therapeutic Effect OnNot AvailableNot AvailablePMC6268471
atherosclerosisAssociated With?decreaseA disorder involving build-up of fatty material and calcium deposition in the arterial wall. It results in partial or complete occlusion of the arterial lumen.PMC9818577
atherosclerosisHas Therapeutic Effect OnNot AvailableA disorder involving build-up of fatty material and calcium deposition in the arterial wall. It results in partial or complete occlusion of the arterial lumen.PMC10334012 , PMC7824569
glioblastomaHas Therapeutic Effect OnNot AvailableA type of brain tumor characterized by its aggressiveness and believed to originate from astrocytes.PMC12466395
heart failureAssociated With?decreaseA disorder characterized by the inability of the heart to pump blood at an adequate volume to meet tissue metabolic requirements, or, the ability to do so only at an elevation in the filling pressure. (NCI CTCAE)PMC10220911
myocardial infarctionHas Therapeutic Effect OnNot AvailableA disorder characterized by gross necrosis of the myocardium; this is due to an interruption of blood supply to the area. (NCI CTCAE)PMC8869647
myocardial infarctionAssociated With?decreaseA disorder characterized by gross necrosis of the myocardium; this is due to an interruption of blood supply to the area. (NCI CTCAE)PMC2464768
heart diseaseHas Therapeutic Effect OnNot AvailableA cardiovascular system disease that involves the heart. (DO)PMC7824569
male infertilityNot AvailableNot AvailableNot AvailablePMC9005387 , PMC9102453
male infertilityHas Therapeutic Effect OnNot AvailableNot AvailablePMC12957189 , PMC12308861
diabetic retinopathyHas Therapeutic Effect OnNot AvailableNot AvailablePMC5793074
neuropathyHas Therapeutic Effect OnNot AvailableA nervous system disease that is located in nerves or nerve cells. (do).PMC11383917
ovarian cancerNot AvailableNot AvailableA female reproductive organ cancer that is located in the ovary. (DO)PMC12021792
coronary artery diseaseAssociated With?decreaseAn artery disease that is characterized by plaque building up along the inner walls of the arteries of the heart resulting in a narrowing of the arteries and a reduced blood supply to the cardiac muscles. (DO)PMC2464768
chronic inflammationHas Therapeutic Effect OnNot AvailableChronic inflammation is a slow, long-term inflammation lasting for prolonged periods of several months to years. Chronic inflammation can damage healthy cells, tissues, and organs. The main causes of the chronic inflammation includes the untreated causes of acute inflammation, such as an infection or injury, an autoimmune disorder and a long-term exposure to irritants, such as industrial chemicals or polluted air.PMC13025991
osteoarthritisDecreased in Blood IndecreaseAn arthritis that has material basis in worn out cartilage located in joint. (DO)PMC9967519
skin cancerAssociated With?decreaseNot AvailablePMC8776015 , PMC11799957
skin cancerHas Therapeutic Effect OnNot AvailableNot AvailablePMC6098906
epilepsyHas Therapeutic Effect OnNot AvailableA brain disease that is characterized by the occurrance of at least two unprovoked seizures resulting from a persistent epileptogenic abnormality of the brain that is able to spontaneously generate paroxysmal activity and typically manifested by sudden brief episodes of altered or diminished consciousness, involuntary movements, or convulsions. (DO)PMC11383917
Parkinson's diseaseDecreased in Blood IndecreaseA long-term degenerative disorder of the central nervous system that mainly affects the motor system. The symptoms generally come on slowly over time.PMC6331815
Parkinson's diseaseHas Therapeutic Effect OnNot AvailableA long-term degenerative disorder of the central nervous system that mainly affects the motor system. The symptoms generally come on slowly over time.PMC11654954
blindnessHas Therapeutic Effect OnNot AvailableA lack of vision, due to neurological or physiological factors.PMC7824569
neurodegenerative diseaseHas Therapeutic Effect OnNot AvailableA central nervous system disease that results in the progressive deterioration of function or structure of neurons. (DO)PMC5471551 , PMC11383917
periodontal diseaseAssociated With?Not AvailableA disorder in the gingival tissue around the teeth. (NCI CTCAE)PMC12924582 , PMC12924582
periodontal diseaseHas Therapeutic Effect OnNot AvailableA disorder in the gingival tissue around the teeth. (NCI CTCAE)PMC12924582
periodontal diseaseAssociated With?inverseA disorder in the gingival tissue around the teeth. (NCI CTCAE)PMC12924582
periodontal diseaseNot AvailableNot AvailableA disorder in the gingival tissue around the teeth. (NCI CTCAE)PMC8600207
brain cancerHas Therapeutic Effect OnNot AvailableNot AvailablePMC9615186
renal fibrosisHas Therapeutic Effect OnNot AvailableNot AvailablePMC12287420 , PMC13237055
squamous cell carcinomaAssociated With?decreaseA carcinoma that derives from squamous epithelial cells. (DO)PMC5000748 , PMC8911995
neurological dysfunctionHas Therapeutic Effect OnNot AvailableNot AvailablePMC13249380
Toxic encephalopathyHas Therapeutic Effect OnNot AvailableNot AvailablePMC9457803 , PMC13249380
periodontitisNot AvailableNot AvailableNot AvailablePMC6153907
ulcerative colitisHas Therapeutic Effect OnNot AvailableA health condition characterized by inflammation of the colon. A type of IBD.PMC13211753
colitisHas Therapeutic Effect OnNot AvailableA disorder characterized by inflammation of the colon. (NCI CTCAE)PMC11898642
macular degenerationHas Therapeutic Effect OnNot AvailableA retinal degeneration characterized by gradual deterioration of light-sensing cells in the tissues at the back of the eye and has symptom vision loss. (DO)PMC7932781
hepatic fibrosisHas Therapeutic Effect OnNot AvailableNot AvailablePMC13237055
vascular dementiaDecreased in Blood IndecreaseNot AvailablePMC6331815
prostate carcinomaHas Therapeutic Effect OnNot AvailableNot AvailablePMC4632414
pancreatitisHas Therapeutic Effect OnNot AvailableNot AvailablePMC6268471
steatotic liver diseaseHas Therapeutic Effect OnNot AvailableNot AvailablePMC4963867
skin diseaseHas Therapeutic Effect OnNot AvailableNot AvailablePMC11357401
eye diseaseAssociated With?Not AvailableNot AvailablePMC11243680
Abnormality of mitochondrial metabolismHas Therapeutic Effect OnNot AvailableNot AvailablePMC13192163 , PMC13192163
Oxidative StressHas Therapeutic Effect OnNot AvailableNot AvailablePMC12021792 , PMC8998295
cardiovascular disorderAssociated With?Not AvailableNot AvailablePMC10220911 , PMC10187563
cardiovascular disorderAssociated With?decreaseNot AvailablePMC3703873 , PMC80172
cardiovascular disorderNot AvailableNot AvailableNot AvailablePMC7022261 , PMC10777738
cardiovascular disorderHas Therapeutic Effect OnNot AvailableNot AvailablePMC7568196
Chronic DiseaseHas Therapeutic Effect OnNot AvailableNot AvailablePMC11769159 , PMC6056767
Chronic DiseaseAssociated With?Not AvailableNot AvailablePMC7412346 , PMC12567243
Chronic DiseaseAssociated With?decreaseNot AvailablePMC80172
MortalityAssociated With?decreaseNot AvailablePMC11357572
MortalityAssociated With?Not AvailableNot AvailablePMC3213013 , PMC8275518
Endoplasmic Reticulum StressHas Therapeutic Effect OnNot AvailableNot AvailablePMC12466678
DNA DamageHas Therapeutic Effect OnNot AvailableNot AvailablePMC12348896 , PMC11243680
HypercholesterolemiaNot AvailableNot AvailableNot AvailablePMC11357572
FibrosisHas Therapeutic Effect OnNot AvailableNot AvailablePMC13237055 , PMC13237055
inflammatory diseaseHas Therapeutic Effect OnNot AvailableNot AvailablePMC5666732 , PMC11243680
Congenital AbnormalitiesHas Therapeutic Effect OnNot AvailableNot AvailablePMC10334136
Abnormal sperm morphologyHas Therapeutic Effect OnNot AvailableNot AvailablePMC5922223
CarcinogenesisHas Therapeutic Effect OnNot AvailableNot AvailablePMC8911995 , PMC11243680
MorbidityAssociated With?Not AvailableNot AvailablePMC3213013
ApoptosisHas Therapeutic Effect OnNot AvailableNot AvailablePMC11654954
metabolic dysfunction-associated steatotic liver diseaseDecreased in Blood IndecreaseNot AvailablePMC9204822
Skin DiseasesHas Therapeutic Effect OnNot AvailableNot AvailablePMC11357401
Diabetes ComplicationsHas Therapeutic Effect OnNot AvailableNot AvailablePMC5471551
Skin AgingHas Therapeutic Effect OnNot AvailableNot AvailablePMC11783858
ErythemaHas Therapeutic Effect OnNot AvailableNot AvailablePMC3257702 , PMC8776015
Reduced sperm motilityHas Therapeutic Effect OnNot AvailableNot AvailablePMC5922223
Skin burnHas Therapeutic Effect OnNot AvailableNot AvailablePMC8398942
subarachnoid hemorrhageHas Therapeutic Effect OnNot AvailableNot AvailablePMC11383917
hip fractureAssociated With?decreaseNot AvailablePMC8003428
OligozoospermiaHas Therapeutic Effect OnNot AvailableNot AvailablePMC5922223
Atherosclerotic lesionAssociated With?increaseNot AvailablePMC11357572
gingivitisNot AvailableNot AvailableNot AvailablePMC6153907
spinal cord injuryHas Therapeutic Effect OnNot AvailableNot AvailablePMC11383917
spinal cord injuryNot AvailableNot AvailableNot AvailablePMC12466678
Carotid Intima-Media ThicknessAssociated With?decreaseNot AvailablePMC2464768
Chronic constipationAssociated With?decreaseNot AvailablePMC11432863
oral submucous fibrosisHas Therapeutic Effect OnNot AvailableNot AvailablePMC13237055
Lipid PeroxidationHas Therapeutic Effect OnNot AvailableNot AvailablePMC6153601
interstitial nephritisHas Therapeutic Effect OnNot AvailableNot AvailablePMC13237055
Exposure Sources
Source IDSourceSectorReference
CEDs000010Insecticides?Insecticides are synthetic chemicals designed to control or eliminate insect pests that threaten crops and other agricultural products.Agriculture & land managementPubChem
CEDs000233Brushes?Brushes used in personal care and cosmetics can be a source of synthetic chemical contamination due to the materials and coatings used in their manufacturing.Personal care & cosmeticsPubChem
CEDs000490Personal care & cosmeticsNot Available
CEDs000503Tents Or Canopies?Tents and canopies used in various applications can be a source of synthetic chemical contamination primarily due to the materials from which they are made.Building & ConstructionPubChem
CEDs000506Antennas?Antennas, commonly used in communication technologies, can be a source of synthetic chemical contamination through the materials and coatings used in their construction.Electrical & Electronic EquipmentPubChem
CEDs000508Coils?Coils are components used in various electrical and electronic applications, such as transformers, inductors, and motors.Electrical & Electronic EquipmentPubChem
CEDs000511Conductors Or Conductive Bodies Characterised By The Conductive Materials?Conductors, or conductive bodies, are materials that allow the flow of electrical current, typically made from metals such as copper, aluminum, or silver.Electrical & Electronic EquipmentPubChem
CEDs000517Electric Switches?Electric switches, integral components in numerous devices, can be a source of synthetic chemical contamination due to the materials and manufacturing processes involved in their production.Electrical & Electronic EquipmentPubChem
CEDs000518Electrically Stimulated Smoking Devices?Electrically stimulated smoking devices, commonly known as e-cigarettes or vape pens, utilize electrical components to heat a liquid solution, often containing nicotine, flavorings, and other additives, to produce an aerosol for inhalation.Electrical & Electronic EquipmentPubChem
CEDs000519Electrodes?Electrodes, used in various electrical and electronic applications, can be a source of synthetic chemical contamination due to the materials from which they are constructed and the processes involved in their manufacturing.Electrical & Electronic EquipmentPubChem
CEDs000520Emergency Protective Devices?Emergency protective devices, such as circuit breakers and surge protectors, are essential components in electrical systems designed to prevent damage from overcurrent and surges.Electrical & Electronic EquipmentPubChem
CEDs000521Fixed Capacitors And Their Manufacture?Fixed capacitors are passive electronic components used to store and release electrical energy, playing a critical role in various circuits.Electrical & Electronic EquipmentPubChem
CEDs000524Hybrid Capacitors?Hybrid capacitors are energy storage devices that combine the properties of electrolytic and supercapacitors, utilizing a combination of electrochemical principles to achieve higher energy density and power density.Electrical & Electronic EquipmentPubChem
CEDs000539Video Games?Video games, through their production and disposal processes, can be a source of synthetic chemical contamination.Electrical & Electronic EquipmentPubChem
CEDs000543Cellar Tools?Cellar tools, commonly used in wine production and other fermentation processes, may pose a risk of synthetic chemical contamination if not properly maintained or if manufactured from substandard materials.Food, food processing & cookwarePubChem
CEDs000544Fermentation Processes For Beer?Fermentation processes for beer involve the conversion of sugars into alcohol and carbon dioxide by yeast.Food, food processing & cookwarePubChem
CEDs000545Food Preservation?Food preservation often involves the use of synthetic chemicals, such as preservatives, flavor enhancers, and color additives, to extend shelf life and enhance the sensory qualities of food products.Food, food processing & cookwarePubChem
CEDs000546Molasses And Treatment Of Molasses?Molasses is a thick, viscous byproduct of sugar production, derived from the extraction of sugar cane or sugar beet juice.Food, food processing & cookwarePubChem
CEDs000547Preparation Of Malt?Malt preparation involves the germination and drying of cereal grains, primarily barley, to produce malt for brewing and food products.Food, food processing & cookwarePubChem
CEDs000548Preparation Of Vinegar?Vinegar is produced through the fermentation of ethanol by acetic acid bacteria, resulting in a solution that typically contains 4-8% acetic acid.Food, food processing & cookwarePubChem
CEDs000549Preparation Of Wine Or Sparkling Wine?The preparation of wine or sparkling wine involves various stages, including fermentation, aging, and bottling, which can introduce potential sources of synthetic chemical contamination.Food, food processing & cookwarePubChem
CEDs000550Preparation Of Wort?The preparation of wort involves the extraction of sugars from malted grains, a crucial step in the brewing process.Food, food processing & cookwarePubChem
CEDs000551Processing Fish?Processing fish can lead to synthetic chemical contamination through various stages of production and preservation.Food, food processing & cookwarePubChem
CEDs000552Processing Meats?Processing meats can lead to synthetic chemical contamination primarily through the use of additives and preservatives.Food, food processing & cookwarePubChem
CEDs000555Bleaching Agents?Bleaching agents are chemical substances used to whiten or lighten materials, often employed in various cleaning products for their stain removal and disinfecting properties.Household cleaning & consumer productsPubChem
CEDs000556Cigar Cigarettes?Cigar cigarettes are a source of synthetic chemical contamination due to the combustion of various tobacco blends and additives.Household cleaning & consumer productsPubChem
CEDs000559Non Electric Simulated Smoking Devices?Non-electric simulated smoking devices, often designed to mimic the experience of smoking without combustion, can be sources of synthetic chemical contamination due to the materials and chemicals used in their construction and operation.Household cleaning & consumer productsPubChem
CEDs000560Other Smoking Requisites?Other smoking requisites, including items such as lighters, matches, and rolling papers, can introduce synthetic chemical contamination through various components and additives.Household cleaning & consumer productsPubChem
CEDs000561Perfumes Within Detergents And Soaps?Perfumes within detergents and soaps are synthetic fragrance compounds added to enhance the sensory experience of cleaning products.Household cleaning & consumer productsPubChem
CEDs000562Pipe Accessories?Pipe accessories, such as fittings, connectors, and seals, are components used in plumbing systems to facilitate the flow of liquids and gases.Household cleaning & consumer productsPubChem
CEDs000563Soap Detergents?Soap detergents are synthetic surfactants designed to enhance the cleaning efficacy of water by reducing surface tension, allowing for better interaction with dirt and grease.Household cleaning & consumer productsPubChem
CEDs000564Soap Dispensers?Soap dispensers, commonly used for dispensing liquid soaps and sanitizers, can become a source of synthetic chemical contamination due to the materials used in their construction and the products they dispense.Household cleaning & consumer productsPubChem
CEDs000566Tobacco Pipes?Tobacco pipes, often made from materials such as plastic, wood, or metal, can serve as sources of synthetic chemical contamination due to the residues left by tobacco products.Household cleaning & consumer productsPubChem
CEDs000567Tobacco Product Cases?Tobacco product cases can serve as a source of synthetic chemical contamination due to the presence of various additives and chemicals used in tobacco processing and product manufacturing.Household cleaning & consumer productsPubChem
CEDs000569Tobacco Smoke Filters?Tobacco smoke filters are designed to reduce the inhalation of harmful substances in cigarette smoke, including tar and other particulate matter.Household cleaning & consumer productsPubChem
CEDs000578Making Cigars?The process of making cigars involves several steps, including the cultivation of tobacco, fermentation, and the application of various additives to enhance flavor and preservation.Industrial manufacturing & chemical processingPubChem
CEDs000580Manufacture Preparation Of Tobacco Products?The manufacture and preparation of tobacco products involve various processes that can result in the introduction of synthetic chemicals into the environment.Industrial manufacturing & chemical processingPubChem
CEDs000581Paper Making Machines?Paper making machines utilize various synthetic chemicals throughout the production process, including additives, coatings, and bleaching agents.Industrial manufacturing & chemical processingPubChem
CEDs000596Acaricides?Acaricides are synthetic chemicals specifically designed to target and control mite populations that can damage crops and plants.Agriculture & land managementPubChem
CEDs000597Chemosterilants?Chemosterilants are synthetic chemicals designed to induce sterility in target pest populations, thereby controlling their reproduction and mitigating damage to crops.Agriculture & land managementPubChem
CEDs000598Fertiliser Distributors?Fertiliser distributors play a critical role in the supply of synthetic fertilizers, which are widely used to enhance soil fertility and crop yield.Agriculture & land managementPubChem
CEDs000600Herbicides And Algicides?Herbicides and algicides are synthetic chemicals primarily used to control unwanted plants and algae in various environments.Agriculture & land managementPubChem
CEDs000602Molluscicides?Molluscicides are synthetic chemicals specifically designed to control and eliminate mollusks, such as snails and slugs, which can be detrimental to crops and agricultural productivity.Agriculture & land managementPubChem
CEDs000603Nematocides?Nematocides are synthetic chemicals specifically designed to control nematodes, which are microscopic roundworms that can cause significant damage to crops and plants.Agriculture & land managementPubChem
CEDs000604Pest Attractants?Pest attractants are synthetic chemicals designed to lure specific pests for monitoring or control purposes.Agriculture & land managementPubChem
CEDs000605Pest Repellants?Pest repellents, often formulated from synthetic chemicals, are widely used to protect crops from insect infestations and other pests.Agriculture & land managementPubChem
CEDs000606Plant Growth Regulators?Plant Growth Regulators (PGRs) are synthetic chemicals designed to influence the growth and development of plants.Agriculture & land managementPubChem
CEDs000607Rodenticides(1)?Rodenticides are synthetic chemicals specifically formulated to control rodent populations, serving as a crucial tool in managing pests that can damage crops and spread diseases.Agriculture & land managementPubChem
CEDs000608Rodenticides?Rodenticides are chemical substances specifically designed to control rodent populations by causing death through various mechanisms, including anticoagulation or neurotoxicity.Agriculture & land managementPubChem
CEDs000609Aftershave?Aftershave is a grooming product typically used to soothe and protect the skin following shaving.Personal care & cosmeticsPubChem
CEDs000610Aftersun Products?Aftersun products are designed to soothe and hydrate the skin after sun exposure, often containing various synthetic chemicals such as emollients, preservatives, and fragrances.Personal care & cosmeticsPubChem
CEDs000611Anti Perspirants Or Body Deoderants?Antiperspirants and body deodorants commonly contain synthetic chemicals such as aluminum compounds, parabens, and synthetic fragrances.Personal care & cosmeticsPubChem
CEDs000612Body Washing Or Cleaning Implements?Body washing or cleaning implements, such as synthetic sponges, loofahs, and washcloths, can be sources of synthetic chemical contamination due to the materials used in their production.Personal care & cosmeticsPubChem
CEDs000613Depilatories?Depilatories are products designed to remove unwanted hair through the application of synthetic chemicals that break down the protein structure of hair, facilitating its removal.Personal care & cosmeticsPubChem
CEDs000614Essential Oils Or Perfumes?Essential oils and perfumes are complex mixtures of volatile compounds derived from natural or synthetic sources, commonly used for their aromatic properties.Personal care & cosmeticsPubChem
CEDs000615Eye Makeup Products?Eye makeup products, including mascaras, eyeliners, and eyeshadows, often contain a variety of synthetic chemicals such as pigments, preservatives, and film-forming agents.Personal care & cosmeticsPubChem
CEDs000616Face Mask Cosmetics?Face mask cosmetics often contain a variety of synthetic chemicals, including preservatives, emulsifiers, and fragrances, which can contribute to chemical contamination.Personal care & cosmeticsPubChem
CEDs000617Lip Care Products?Lip care products, including lipsticks, balms, and glosses, often contain a variety of synthetic chemicals such as parabens, phthalates, and synthetic fragrances.Personal care & cosmeticsPubChem
CEDs000618Lip Makeup Products?Lip makeup products, such as lipsticks, lip glosses, and lip liners, often contain a variety of synthetic chemicals, including pigments, preservatives, and emollients.Personal care & cosmeticsPubChem
CEDs000619Manicure Pedicure?Manicure and pedicure procedures often involve the use of various synthetic chemicals, including solvents, nail polishes, and nail adhesives.Personal care & cosmeticsPubChem
CEDs000620Card Games?Card games often utilize synthetic materials for playing cards and associated gaming equipment, which may contain various chemicals such as polyvinyl chloride (PVC), plastics, and dyes.Recreation & sports surfacesPubChem
CEDs000630Toys?Toys, particularly those made from synthetic materials such as plastics, can be a source of chemical contamination due to the presence of various additives and compounds used in their production.Recreation & sports surfacesPubChem
CEDs000632Apparel?Apparel production often involves the use of various synthetic chemicals, including dyes, finishing agents, and preservatives.Textiles, leather & furnishingsPubChem
CEDs000642Footwear?Footwear production often involves the use of various synthetic chemicals, such as adhesives, dyes, and treatments, which can contribute to environmental contamination.Textiles, leather & furnishingsPubChem
CEDs000643Headwear?Headwear made from synthetic materials often incorporates chemicals used in the manufacturing and finishing processes, such as dyes, flame retardants, and water repellents.Textiles, leather & furnishingsPubChem
CEDs000650Purses Luggage Hand Bags?Purses, luggage, and handbags are often manufactured using synthetic materials such as polyvinyl chloride (PVC), polyurethane, and various types of nylon.Textiles, leather & furnishingsPubChem
CEDs000657Surface Finishing Of Leather?Surface finishing of leather often involves the use of various synthetic chemicals, including dyes, resins, and finishing agents.Textiles, leather & furnishingsPubChem
CEDs000662Yarns Or Threads?Yarns or threads used in textiles can be a source of synthetic chemical contamination due to the production processes and treatments they undergo.Textiles, leather & furnishingsPubChem
CEDs000667Gaseous Fire Fighting?Gaseous fire fighting systems utilize synthetic chemicals, such as halocarbons and inert gases, to suppress fires through chemical and physical processes.Fire suppression systems & agentsPubChem
CEDs000669PFAS Fire Fighting Foam?PFAS fire fighting foam refers to a class of synthetic foams containing per- and polyfluoroalkyl substances (PFAS), which are designed to suppress flammable liquid fires.Fire suppression systems & agentsPubChem
CEDs000674Bridle Bits?Bridle bits, commonly used in equestrian activities, can be a source of synthetic chemical contamination primarily through the materials used in their manufacturing.Agriculture & land managementPubChem
CEDs000677Horse Reins?Horse reins, often made from synthetic materials such as nylon or polyester, can be a source of chemical contamination due to their production and degradation processes.Agriculture & land managementPubChem
CEDs000678Nitrogenous Fertilisers?Nitrogenous fertilizers are synthetic chemical compounds primarily used to enhance plant growth by supplying essential nitrogen, a crucial nutrient for photosynthesis and protein synthesis.Agriculture & land managementPubChem
CEDs000679Phosphatic Fertilisers?Phosphatic fertilizers are synthetic chemical products primarily composed of phosphorus, which is essential for plant growth.Agriculture & land managementPubChem
CEDs000684Cements?Cements are a composite material primarily used as a binding agent in construction applications, formed by the calcination of limestone and clay minerals at high temperatures.Building & ConstructionPubChem
CEDs000685Ceramics?Ceramics can be a source of synthetic chemical contamination through various additives and processing agents used in their production.Building & ConstructionPubChem
CEDs000686Clay Wares?Clay wares are ceramic products made from natural clay, often utilized in various construction applications such as tiles, bricks, and sanitary ware.Building & ConstructionPubChem
CEDs000688Glass Coatings?Glass coatings are synthetic chemical formulations applied to glass surfaces to enhance properties such as durability, UV resistance, and aesthetic appeal.Building & ConstructionPubChem
CEDs000693Silica Glass?Silica glass, primarily composed of silicon dioxide (SiO2), is widely used in various applications, including windows, glass facades, and insulation materials.Building & ConstructionPubChem
CEDs000694Cheese Making?Cheese making involves the fermentation of milk, utilizing bacteria and enzymes to coagulate proteins and develop flavor.Food, food processing & cookwarePubChem
CEDs000696Nanotechnology?Nanotechnology involves the manipulation of materials at the molecular or atomic level, typically within the range of 1 to 100 nanometers.Industrial manufacturing & chemical processingPubChem
CEDs000699Mining Or Quarrying?Mining and quarrying operations can lead to synthetic chemical contamination through the release of various pollutants associated with the extraction and processing of minerals.Mining & metal processingPubChem
CEDs000717Fountain Pens?Fountain pens utilize a liquid ink that often contains synthetic chemicals, including dyes, pigments, and solvents, which can contribute to environmental contamination.Paper, pulp & fiber productsPubChem
CEDs000720Ink Reservoir Pens2?Ink reservoir pens are writing instruments that utilize a reservoir to store ink, which is often composed of synthetic dyes, solvents, and additives.Paper, pulp & fiber productsPubChem
CEDs000726Pens?Pens, commonly utilized for writing and marking, can be a source of synthetic chemical contamination primarily due to the materials used in their manufacturing.Paper, pulp & fiber productsPubChem
CEDs000727Printing Machines Or Presses?Printing machines or presses commonly utilize synthetic chemicals such as inks, solvents, and cleaning agents.Paper, pulp & fiber productsPubChem
CEDs000729Stamps?Stamps, particularly those produced using synthetic inks and adhesives, can contribute to chemical contamination when disposed of improperly.Paper, pulp & fiber productsPubChem
CEDs000730Contact Lens Cases?Contact lens cases are small containers designed to store contact lenses in a sterile environment, typically made from various synthetic materials including plastics such as polypropylene or polycarbonate.Healthcare, pharmaceuticals & veterinary productsPubChem
CEDs000734Coating Compositions?Coating compositions, which include paints, sealants, and varnishes, are formulated with a variety of synthetic chemicals such as solvents, resins, pigments, and additives.Building & ConstructionPubChem
CEDs000735Explosives?Explosives are chemical compounds or mixtures designed to undergo rapid decomposition, releasing energy in the form of gas and heat.Defense & military infrastructurePubChem
CEDs000739Inks?Inks are complex mixtures composed of pigments or dyes, solvents, resins, and additives used primarily for printing and writing applications.Paper, pulp & fiber productsPubChem
CEDs000740Paper?Paper production involves the processing of wood fibers and the use of various chemicals, which can lead to synthetic chemical contamination.Paper, pulp & fiber productsPubChem
CEDs000741Pigment Pastes?Pigment pastes are concentrated dispersions of pigments used to impart color and properties to materials.Paper, pulp & fiber productsPubChem
CEDs000742Leather Tanning?Leather tanning is a process that transforms raw animal hides into durable leather through the application of various chemicals, including chromium salts, aldehydes, and vegetable tannins.Textiles, leather & furnishingsPubChem
CEDs000743Sludge Treatment?Sludge treatment involves the processing of waste materials generated from wastewater treatment plants, which often contain a variety of organic and inorganic substances.Wastewater, sanitation & biosolidsPubChem
CEDs000744Water, Wastewater, & Sewage Treatment?Water, wastewater, and sewage treatment processes are critical for managing and mitigating pollutants in water systems.Wastewater, sanitation & biosolidsPubChem
CEDs00748Animal FeedAgriculture & land managementPMC10734531
CEDs00751FeedAgriculture & land managementPMC10220911
CEDs00774Agricultural By-productsAgriculture & land managementPMC9818577
CEDs01082PharmaceuticalsHealthcare, pharmaceuticals & veterinary productsPMC10734531
CEDs01143DietFood, food processing & cookwarePMC8510019 , PMC10220911
CEDs01144FoodFood, food processing & cookwarePMC9818577 , PMC11185959
CEDs01151FruitsFood, food processing & cookwarePMC11678264 , PMC12466395
CEDs01157FoodsFood, food processing & cookwarePMC8189654 , PMC3491936
CEDs01168Food ProductsFood, food processing & cookwarePMC8911995
CEDs01171MeatFood, food processing & cookwarePMC7022261
CEDs01181Food ItemsFood, food processing & cookwarePMC7266124
CEDs01200VegetablesFood, food processing & cookwarePMC11678264 , PMC3257702
CEDs01208FruitFood, food processing & cookwarePMC10135188 , PMC8434243
CEDs01210Food SupplementsFood, food processing & cookwarePMC7324876
CEDs01211Food MatrixFood, food processing & cookwarePMC13025991 , PMC10187563
CEDs01220Processed FoodsFood, food processing & cookwarePMC4168010 , PMC7324876
CEDs01228Tomato FruitsFood, food processing & cookwarePMC7995756 , PMC9805007
CEDs01245Fruit JuiceFood, food processing & cookwarePMC8393480
CEDs01253Dietary SupplementsFood, food processing & cookwarePMC11964568
CEDs01261Beef BurgersFood, food processing & cookwarePMC9988266
CEDs01267Egg YolkFood, food processing & cookwarePMC4632414 , PMC13010960
CEDs01270Functional FoodFood, food processing & cookwarePMC13468688
CEDs01308Carrot JuiceFood, food processing & cookwarePMC3257702
CEDs01309Red FruitsFood, food processing & cookwarePMC3257702 , PMC13457878
CEDs01311Tomato JuiceFood, food processing & cookwarePMC12800756 , PMC8839513
CEDs01362Ground BeefFood, food processing & cookwarePMC11243680
CEDs01495Fruit ExtractFood, food processing & cookwarePMC8228042
CEDs01582Fruit TissueFood, food processing & cookwarePMC12567243
CEDs01680Vegetable MatricesFood, food processing & cookwarePMC9598241
CEDs01966OleoresinIndustrial manufacturing & chemical processingPMC9818577 , PMC13468688
CEDs02078Industrial WasteWaste management, landfill & incinerationPMC9169564
CEDs02164Tomato WasteWaste management, landfill & incinerationPMC9818577 , PMC9818577
CEDs02845CosmeticsPersonal care & cosmeticsPMC9885113
CEDs02856Cosmetic FormulationsPersonal care & cosmeticsPMC10604252
CEDs02881Cosmetic IndustriesPersonal care & cosmeticsPMC10220911
CEDs02992Petroleum EtherEnergy, oil & gasPMC11306087
Pathways
2 pathwaysPathway Source: PathBank
Targets
StructureProteinUniProt IDOrganismRelationshipDetails
Matrix metalloproteinase-9 structureClick to view 3D structureMatrix metalloproteinase-9P14780HumansKnownNot Available
Caspase-3 structureClick to view 3D structureCaspase-3P42574HumansKnownNot Available
Click to view 3D structureSqualene epoxidaseA7L861Sus scrofaPredicted (SEA)
Prediction Confidence Score
0.373
Applicability Domain
0.412
Statistical Significance
6.00e-05
Supporting Reference Compounds
2
E-value
0.467095
Click to view 3D structureProtein-S-isoprenylcysteine O-methyltransferaseP32584Saccharomyces cerevisiae S288cPredicted (SEA)
Prediction Confidence Score
0.35
Applicability Domain
0.35
Statistical Significance
7.00e-05
Supporting Reference Compounds
1
E-value
0.544945
Click to view 3D structureProtein-S-isoprenylcysteine O-methyltransferaseQ9WVM4Rattus norvegicusPredicted (SEA)
Prediction Confidence Score
0.332
Applicability Domain
0.378
Statistical Significance
8.00e-05
Supporting Reference Compounds
2
E-value
0.622794
Click to view 3D structureSqualene synthase ERG9P29704Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Predicted (SEA)
Prediction Confidence Score
0.304
Applicability Domain
0.304
Statistical Significance
1.20e-04
Supporting Reference Compounds
1
E-value
0.934191
Click to view 3D structureInhibin alpha chainP05111HumansPredicted (SEA)
Prediction Confidence Score
0.292
Applicability Domain
0.292 Low confidence
Statistical Significance
3.60e-04
Supporting Reference Compounds
1
E-value
2.80257
Click to view 3D structureTransient receptor potential cation channel subfamily A member 1Q6RI86Rattus norvegicusPredicted (SEA)
Prediction Confidence Score
0.274
Applicability Domain
0.292 Low confidence
Statistical Significance
0.004
Supporting Reference Compounds
56
E-value
31.4511
Click to view 3D structureTransient receptor potential cation channel subfamily M member 8Q8R455Rattus norvegicusPredicted (SEA)
Prediction Confidence Score
0.274
Applicability Domain
0.292 Low confidence
Statistical Significance
0.0015
Supporting Reference Compounds
23
E-value
11.9109
Click to view 3D structureLanosterol synthaseQ04782YeastPredicted (SEA)
Prediction Confidence Score
0.269
Applicability Domain
0.269 Low confidence
Statistical Significance
9.00e-05
Supporting Reference Compounds
1
E-value
0.700643
Cytochrome P450 2B4 structureClick to view 3D structureCytochrome P450 2B4P00178Oryctolagus cuniculusPredicted (SEA)
Prediction Confidence Score
0.241
Applicability Domain
0.241 Low confidence
Statistical Significance
6.60e-04
Supporting Reference Compounds
1
E-value
5.13805
Transient receptor potential cation channel subfamily V member 1 structureClick to view 3D structureTransient receptor potential cation channel subfamily V member 1Q8NER1HumansPredicted (SEA)
Prediction Confidence Score
0.228
Applicability Domain
0.292 Low confidence
Statistical Significance
0.13
Supporting Reference Compounds
104
E-value
1012.35
Click to view 3D structureRetinoic acid receptor alphaP11416Mus musculusPredicted (SEA)
Prediction Confidence Score
0.228
Applicability Domain
0.231 Low confidence
Statistical Significance
0.002
Supporting Reference Compounds
16
E-value
15.7255
Click to view 3D structureRetinoic acid receptor gammaP18911Mus musculusPredicted (SEA)
Prediction Confidence Score
0.225
Applicability Domain
0.231 Low confidence
Statistical Significance
0.0023
Supporting Reference Compounds
14
E-value
18.2167
Retinoic acid receptor beta structureClick to view 3D structureRetinoic acid receptor betaP22605Mus musculusPredicted (SEA)
Prediction Confidence Score
0.225
Applicability Domain
0.231 Low confidence
Statistical Significance
0.0023
Supporting Reference Compounds
14
E-value
17.9832
Retinoic acid receptor RXR-alpha structureClick to view 3D structureRetinoic acid receptor RXR-alphaP19793HumansPredicted (SEA)
Prediction Confidence Score
0.223
Applicability Domain
0.231 Low confidence
Statistical Significance
0.0512
Supporting Reference Compounds
82
E-value
398.277
Retinoic acid receptor RXR-alpha structureClick to view 3D structureRetinoic acid receptor RXR-alphaP28700Mus musculusPredicted (SEA)
Prediction Confidence Score
0.223
Applicability Domain
0.231 Low confidence
Statistical Significance
0.0023
Supporting Reference Compounds
17
E-value
17.5939
Cellular retinoic acid-binding protein 1 structureClick to view 3D structureCellular retinoic acid-binding protein 1P62965Mus musculusPredicted (SEA)
Prediction Confidence Score
0.223
Applicability Domain
0.231 Low confidence
Statistical Significance
1.80e-04
Supporting Reference Compounds
7
E-value
1.40129
Click to view 3D structureCellular retinoic acid-binding protein 2P22935Mus musculusPredicted (SEA)
Prediction Confidence Score
0.223
Applicability Domain
0.231 Low confidence
Statistical Significance
1.80e-04
Supporting Reference Compounds
7
E-value
1.40129
Click to view 3D structureProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alphaP29703Saccharomyces cerevisiae S288cPredicted (SEA)
Prediction Confidence Score
0.219
Applicability Domain
0.219 Low confidence
Statistical Significance
0.0021
Supporting Reference Compounds
1
E-value
16.5819
Tyrosine-protein phosphatase non-receptor type 1 structureClick to view 3D structureTyrosine-protein phosphatase non-receptor type 1P18031HumansPredicted (SEA)
Prediction Confidence Score
0.218
Applicability Domain
0.3
Statistical Significance
0.1741
Supporting Reference Compounds
197
E-value
1355.12
Click to view 3D structureCellular retinoic acid-binding protein 1P40220Gallus gallusPredicted (SEA)
Prediction Confidence Score
0.217
Applicability Domain
0.231 Low confidence
Statistical Significance
1.70e-04
Supporting Reference Compounds
5
E-value
1.32344
Polyunsaturated fatty acid 5-lipoxygenase structureClick to view 3D structurePolyunsaturated fatty acid 5-lipoxygenaseP09917HumansPredicted (SEA)
Prediction Confidence Score
0.214
Applicability Domain
0.326
Statistical Significance
0.2469
Supporting Reference Compounds
182
E-value
1921.79
Retinoic acid receptor gamma structureClick to view 3D structureRetinoic acid receptor gammaP13631HumansPredicted (SEA)
Prediction Confidence Score
0.213
Applicability Domain
0.231 Low confidence
Statistical Significance
0.0607
Supporting Reference Compounds
52
E-value
472.934
Transient receptor potential cation channel subfamily A member 1 structureClick to view 3D structureTransient receptor potential cation channel subfamily A member 1O75762HumansPredicted (SEA)
Prediction Confidence Score
0.211
Applicability Domain
0.292 Low confidence
Statistical Significance
0.0963
Supporting Reference Compounds
70
E-value
750.077
Click to view 3D structureAldehyde dehydrogenase 1A1P27463Gallus gallusPredicted (SEA)
Prediction Confidence Score
0.211
Applicability Domain
0.211 Low confidence
Statistical Significance
1.60e-04
Supporting Reference Compounds
1
E-value
1.24559
Prostaglandin G/H synthase 2 structureClick to view 3D structureProstaglandin G/H synthase 2P35354HumansPredicted (SEA)
Prediction Confidence Score
0.206
Applicability Domain
0.326
Statistical Significance
0.3917
Supporting Reference Compounds
201
E-value
3049.51
Regulator of chromosome condensation structureClick to view 3D structureRegulator of chromosome condensationP18754HumansKnownNot Available
Low-density lipoprotein receptor structureClick to view 3D structureLow-density lipoprotein receptorP01130HumansKnownNot Available
RAC-alpha serine/threonine-protein kinase structureClick to view 3D structureRAC-alpha serine/threonine-protein kinaseP31749HumansKnownNot Available
Catalase structureClick to view 3D structureCatalaseP04040HumansKnownNot Available
DNA (cytosine-5)-methyltransferase 3A structureClick to view 3D structureDNA (cytosine-5)-methyltransferase 3AQ9Y6K1HumansKnownNot Available
Concentrations
Not Available
External Links
DrugBank IDNot Available
HMDB IDNot Available
FooDB IDNot Available
Phenol Explorer IDNot Available
KNApSAcK IDNot Available
BiGG IDNot Available
BioCyc IDNot Available
METLIN IDNot Available
PDB IDNot Available
Wikipedia LinkLycopene
Chemspider IDNot Available
ChEBI IDNot Available
PubChem Compound ID53477748
Kegg Compound IDNot Available
YMDB IDNot Available
ECMDB IDM2MDB004555
References
Synthesis ReferenceNot Available
MSDSNot Available
General ReferencesNot Available