Dimethoxydimethylsilane (CED0021988)

Record Information

Version

1.0

Creation Date

2016-05-19 03:03:47 UTC

Update Date

2026-08-22 15:44:17 UTC

Accession Number

CHEM009374

Identification

Common Name

Dimethoxydimethylsilane

Class

Small Molecule

Description

Dimethoxydimethylsilane is a chemical compound with the formula C4H12O2Si and an average molecular weight of 120.22 g/mol. Dimethoxydimethylsilane belongs to the organosilicon compounds, a subclass of organometalloid compounds within the organic compounds. The substance is found in or released from 38 recorded sources across various sectors. In the Electrical & Electronic Equipment sector, it is associated with antennas, amplifiers, adjustable resistors, coils, auxiliary devices, and 9 more items. It is detected in drinking water and water supply systems, including tap water, bottled water, desalinated water, and drinking water. Within aquatic systems and sediments, the compound is present in seawater, freshwater, surface water, and groundwater. It is also found in wastewater, sanitation, and biosolids, specifically in wastewater treatment effluent, industrial wastewater, mine wastewater, and unspecified wastewater. Additional sources include the building and construction sector, where it is linked to fencing, waterproofing sprays, and tents or canopies. In the appliances, HVAC, and refrigerants sector, it is found in water heaters and water coolers, among 6 more sectors. Recorded exposure routes for dimethoxydimethylsilane include oral, inhalation, and touch.

Contaminant Type

Chemical Structure

MOL SDF PDB SMILES InChI

Synonyms

Not Available

Chemical Formula

C₄H₁₂O₂Si

Average Molecular Mass

120.223 g/mol

Monoisotopic Mass

120.061 g/mol

CAS Registry Number

1112-39-6

IUPAC Name

dimethoxydimethylsilane

Traditional Name

silane, dimethoxydimethyl-

SMILES

CO[Si](C)(C)OC

InChI Identifier

InChI=1S/C4H12O2Si/c1-5-7(3,4)6-2/h1-4H3

InChI Key

JJQZDUKDJDQPMQ-UHFFFAOYSA-N

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as alkoxysilanes. These are organosilicon compounds with the general formula RO[Si](OR')(R'')(R''') (R,R' = organyl; R'',R''' = any atom).

Kingdom

Organic compounds

Super Class

Organometallic compounds

Class

Organometalloid compounds

Sub Class

Organosilicon compounds

Direct Parent

Alkoxysilanes

Alternative Parents

Substituents

Alkoxysilane
Silyl ether
Organoheterosilane
Organic metalloid salt
Organic oxygen compound
Hydrocarbon derivative
Organic salt
Organooxygen compound
Aliphatic acyclic compound

Molecular Framework

Aliphatic acyclic compounds

External Descriptors

Not Available

Biological Properties

Status

Detected and Not Quantified

Origin

Not Available

Cellular Locations

Not Available

Biofluid Locations

Not Available

Tissue Locations

Not Available

Applications

Not Available

Biological Roles

Not Available

Chemical Roles

Not Available

Organoleptic Effects

Not Available

Physical Properties

State

Not Available

Appearance

Not Available

Experimental Properties

Property	Value
Melting Point	Not Available
Boiling Point	Not Available
Solubility	Not Available

Predicted Properties

Property	Value	Source
Water Solubility	45.3 g/L	ALOGPS
logP	1.51	ALOGPS
logP	0.3	ChemAxon
logS	-0.42	ALOGPS
pKa (Strongest Basic)	-3.8	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	2	ChemAxon
Hydrogen Donor Count	0	ChemAxon
Polar Surface Area	18.46 Å²	ChemAxon
Rotatable Bond Count	2	ChemAxon
Refractivity	25.99 m³·mol⁻¹	ChemAxon
Polarizability	12.36 Å³	ChemAxon
Number of Rings	0	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	Yes	ChemAxon
MDDR-like Rule	No	ChemAxon

Spectra

Spectrum Type	Description	Splash Key	Deposition Date	View
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-00di-0900000000-3d70c1b18053fa952b87	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-00dr-7900000000-6f043fdfc05e2afbe3c0	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-00di-7900000000-caf2ee28c2b7167c68ac	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-014i-1900000000-968ac0b769afed3ff744	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-014r-9400000000-b60ebd2f7cd7bfe5b250	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-0a4r-9000000000-1a8e0525fc586c10c938	Not Available	View Spectrum

Toxicity Profile

Mechanism of Toxicity

Not Available

Carcinogenicity (IARC Classification)

Not Available

Minimum Risk Level

Not Available

Symptoms

Not Available

Treatment

Not Available

Toxicity Values

Toxicity Value	Unit	Value Range	Organism	Dose Descriptor	Route of Exposure	Predicted or Experimental	Reference
2320.0	Log mg/kg	[1300:4100]	Rat	LD50	oral	predicted	Not Available

Health Effects

Health Effect	Relationship	Direction	Reference

Exposure Sources

Source ID	Source	Sector	Reference
3	Irrigation water	Agriculture & land management	Not Available
27	Water Coolers	Appliances, HVAC & refrigerants	Not Available
43	Water heaters	Appliances, HVAC & refrigerants	Not Available
50	Groundwater	Aquatic systems & sediments	Not Available
51	Surface water	Aquatic systems & sediments	Not Available
52	Seawater	Aquatic systems & sediments	Not Available
53	Freshwater	Aquatic systems & sediments	Not Available
70	Stormwater runoff	Automotive & urban infrastructure	Not Available
88	Waterproofing sprays	Building & Construction	Not Available
115	Drinking water	Drinking water & water supply	Not Available
116	Tap water	Drinking water & water supply	Not Available
117	Bottled water	Drinking water & water supply	Not Available
118	Desalinated water	Drinking water & water supply	Not Available
181	Ballast water	Marine, shipping & aquaculture	Not Available
182	Bilge water	Marine, shipping & aquaculture	Not Available
233	Brushes	Personal care & cosmetics	Not Available
468	Industrial wastewater	Wastewater, sanitation & biosolids	Not Available
470	Wastewater treatment effluent	Wastewater, sanitation & biosolids	Not Available
475	Mine wastewater	Wastewater, sanitation & biosolids	Not Available
477	Wastewater, unspecified	Wastewater, sanitation & biosolids	Not Available
496	Fencing	Building & Construction	Not Available
503	Tents Or Canopies	Building & Construction	Not Available
504	Adjustable Resistors	Electrical & Electronic Equipment	Not Available
505	Amplifiers	Electrical & Electronic Equipment	Not Available
506	Antennas	Electrical & Electronic Equipment	Not Available
507	Auxiliary Devices	Electrical & Electronic Equipment	Not Available
508	Coils	Electrical & Electronic Equipment	Not Available
513	Cores Yokes Or Armatures	Electrical & Electronic Equipment	Not Available
514	Discharge Lamps	Electrical & Electronic Equipment	Not Available
520	Emergency Protective Devices	Electrical & Electronic Equipment	Not Available
529	Power Cables	Electrical & Electronic Equipment	Not Available
533	Sparking Plugs	Electrical & Electronic Equipment	Not Available
535	Superconducting Magnets And Superconducting Coils	Electrical & Electronic Equipment	Not Available
536	Superconductive Or Hyperconductive Conductors Cables Or Transmission Lines	Electrical & Electronic Equipment	Not Available
537	Television Systems	Electrical & Electronic Equipment	Not Available
538	Thin Magnetic Films	Electrical & Electronic Equipment	Not Available
549	Preparation Of Wine Or Sparkling Wine	Food, food processing & cookware	Not Available
556	Cigar Cigarettes	Household cleaning & consumer products	Not Available
571	Coins	Household items	Not Available
581	Paper Making Machines	Industrial manufacturing & chemical processing	Not Available
613	Depilatories	Personal care & cosmetics	Not Available
619	Manicure Pedicure	Personal care & cosmetics	Not Available
627	Roulette Games	Recreation & sports surfaces	Not Available
638	Decorating Textiles	Textiles, leather & furnishings	Not Available
643	Headwear	Textiles, leather & furnishings	Not Available
650	Purses Luggage Hand Bags	Textiles, leather & furnishings	Not Available
652	Ropes	Textiles, leather & furnishings	Not Available
655	Slide Fasteners	Textiles, leather & furnishings	Not Available
657	Surface Finishing Of Leather	Textiles, leather & furnishings	Not Available
659	Transfer Printing	Textiles, leather & furnishings	Not Available

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this synthetic chemical

Targets

Structure	Protein	UniProt ID	Organism	Relationship	Details
Click to view 3D structure	Proline iminopeptidase	O32449	Serratia marcescens	Predicted (SEA)	706.092
Click to view 3D structure	Carbonic anhydrase 9	Q16790	Humans	Predicted (SEA)	7745.92
Click to view 3D structure	Carbonic anhydrase 7	P43166	Humans	Predicted (SEA)	7695.4
Click to view 3D structure	Carbonic anhydrase 12	O43570	Humans	Predicted (SEA)	7739.3
Click to view 3D structure	Casein kinase II subunit alpha	P68400	Humans	Predicted (SEA)	7761.02
Click to view 3D structure	Carbonic anhydrase 14	Q9ULX7	Humans	Predicted (SEA)	7682.71
Click to view 3D structure	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Q13627	Humans	Predicted (SEA)	7766.32
Click to view 3D structure	Carbonic anhydrase 2	P00918	Humans	Predicted (SEA)	7776.51
Click to view 3D structure	Cytochrome P450 1A2	P05177	Humans	Predicted (SEA)	7778.31
Click to view 3D structure	PA-I galactophilic lectin	Q05097	Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228)	Predicted (SEA)	190.964
Click to view 3D structure	Vascular endothelial growth factor receptor 2	P35968	Humans	Predicted (SEA)	7779.47
Click to view 3D structure	Cytochrome P450 2C19	P33261	Humans	Predicted (SEA)	7779.55
Click to view 3D structure	Dual specificity protein kinase CLK4	Q9HAZ1	Humans	Predicted (SEA)	7769.98
Click to view 3D structure	Serine/threonine-protein kinase Chk1	O14757	Humans	Predicted (SEA)	7775.27
Click to view 3D structure	Carbonic anhydrase 1	P00915	Humans	Predicted (SEA)	7777.29
Click to view 3D structure	NACHT, LRR and PYD domains-containing protein 3	Q96P20	Humans	Predicted (SEA)	7677.26
Click to view 3D structure	Epidermal growth factor receptor	P00533	Humans	Predicted (SEA)	7780.1
Click to view 3D structure	Cytochrome P450 3A4	P08684	Humans	Predicted (SEA)	7782.59
Click to view 3D structure	Inward rectifier potassium channel 2	P35561	Mus musculus	Predicted (SEA)	4630.16
Click to view 3D structure	Serine/threonine-protein phosphatase 5	P53042	Rattus norvegicus	Predicted (SEA)	2959.59
Click to view 3D structure	Endochitinase A1	Q873Y0	Aspergillus fumigatus	Predicted (SEA)	3060.1
Click to view 3D structure	DNA dC->dU-editing enzyme APOBEC-3G	Q9HC16	Humans	Predicted (SEA)	7689.63
Click to view 3D structure	Serine/threonine-protein kinase pim-1	P11309	Humans	Predicted (SEA)	7777.06
Click to view 3D structure	Luciferin 4-monooxygenase	P08659	Photinus pyralis	Predicted (SEA)	7703.26
Click to view 3D structure	LIM domain kinase 1	P53667	Humans	Predicted (SEA)	7773.4