Boron (CED0000937)

Record Information
Version1.0
Creation Date2016-05-19 04:38:01 UTC
Update Date2026-05-14 19:07:46 UTC
Accession NumberCHEM014891
Identification
Common NameBoron
ClassSmall Molecule
Description
Boron belongs to the miscellaneous mixed metal/non-metals, a class of mixed metal/non-metal compounds within the inorganic compounds. It has the formula BH3 and an average molecular weight of 13.84 g/mol. In industrial contexts, boron is used as a flame retardant (PMC10259682) and can occur as a degradant or impurity (PMC10874124). Biologically and environmentally, it serves as a nutrient (PMC10874124) and micronutrient (PMC12735847), though it is also classified as a biological toxin (PMC11678992). Boron is found in or released from 44 recorded sources. These include household items such as key rings, badges, and credit card holders; household cleaning and consumer products including tobacco pipes, pipe accessories, other smoking requisites, non electric simulated smoking devices, and ash trays; food, food processing and cookware such as the treatment of hops, processing fish, and food contact materials; building and construction materials including roofs, ladders, floors, fencing, and ceilings; and electrical and electronic equipment such as coils, auxiliary devices, antennas, amplifiers, adjustable resistors, and 21 others. Regarding plastics, boron is released in polyethylene terephthalate but is not detected in polystyrene. Recorded exposure routes include oral, touch, and inhalation. The compound is associated with several health effects, including anorexia (PMC10874124), dermatitis (PMC10874124), diarrhea (PMC10874124), botulism (PMC10802438), and breast cancer (PMC10605826). Conversely, boron has a therapeutic effect on breast cancer (PMC10351539), multiple myeloma (PMC10351539), and cancer (PMC10351539, PMC9416915). It is used as a treatment for inflammation (PMC6273063), hepatitis (PMC6273063), leukemia (PMC6273063), thyroid cancer (PMC12401129), cancer (PMC12373437, PMC13024029, PMC13289660), breast cancer (PMC11084730, PMC13414665), lung cancer (PMC13414665), and hepatocellular carcinoma (PMC13414665).
Contaminant TypeNot Available
Chemical Structure
Synonyms
ValueSource
b(3+)ChEBI
Boron, ion(3+)ChEBI
BHMDB
Boron metallicHMDB
Trona elemental boronHMDB
Chemical FormulaBH3
Average Molecular Mass13.835 g/mol
Monoisotopic Mass14.033 g/mol
CAS Registry Number7440-42-8
IUPAC Nameboron(3+) ion
Traditional Nameboron(3+) ion
SMILESB
InChI IdentifierInChI=1S/BH3/h1H3
InChI KeyUORVGPXVDQYIDP-UHFFFAOYSA-N
Chemical Taxonomy
Description Belongs to the class of inorganic compounds known as homogeneous metalloid compounds. These are inorganic compounds containing only metal atoms,with the largest atom being a metalloid atom.
KingdomInorganic compounds
Super ClassHomogeneous metal compounds
ClassHomogeneous metalloid compounds
Sub ClassNot Available
Direct ParentHomogeneous metalloid compounds
Alternative ParentsNot Available
Substituents
  • Homogeneous metalloid
Molecular FrameworkNot Available
External Descriptors
Biological Properties
StatusDetected and Not Quantified
OriginNot Available
Cellular LocationsNot Available
Biofluid LocationsNot Available
Tissue LocationsNot Available
ApplicationsNot Available
Biological Roles
Chemical RolesNot Available
Organoleptic EffectsNot Available
Physical Properties
StateNot Available
AppearanceNot Available
Experimental Properties
PropertyValue
Melting PointNot Available
Boiling PointNot Available
SolubilityNot Available
Predicted Properties
PropertyValueSource
logP0.33ChemAxon
Physiological Charge3ChemAxon
Hydrogen Acceptor Count0ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area0 ŲChemAxon
Rotatable Bond Count0ChemAxon
Refractivity0 m³·mol⁻¹ChemAxon
Polarizability1.78 ųChemAxon
Number of Rings0ChemAxon
BioavailabilityYesChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleNoChemAxon
Spectra
Spectra
Spectrum TypeDescriptionSplash KeyDeposition DateView
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-014i-9000000000-1e0b2df827e720411fadNot AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-014i-9000000000-1e0b2df827e720411fadNot AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-014i-9000000000-1e0b2df827e720411fadNot AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-03di-9000000000-cd741404fcfd0c1f7e88Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-03di-9000000000-cd741404fcfd0c1f7e88Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-03di-9000000000-cd741404fcfd0c1f7e88Not AvailableView Spectrum
Toxicity Profile
Mechanism of ToxicityNot Available
Carcinogenicity (IARC Classification)Not Available
Minimum Risk LevelNot Available
SymptomsNot Available
TreatmentNot Available
Toxicity ValuesNot Available
Health Effects
Health EffectRelationshipDirectionReference
lung canceris_treatment_forNot AvailablePMC13414665
inflammationis_treatment_forNot AvailablePMC6273063
canceris_treatment_forNot AvailablePMC12373437 , PMC13024029 , PMC13289660
cancerhas_therapeutic_effect_onNot AvailablePMC10351539 , PMC9416915
breast cancerassociated_withNot AvailablePMC10605826
breast canceris_treatment_forNot AvailablePMC11084730 , PMC13414665
breast cancerhas_therapeutic_effect_onNot AvailablePMC10351539
multiple myelomahas_therapeutic_effect_onNot AvailablePMC10351539
diarrheaassociated_withNot AvailablePMC10874124
Hepatocellular carcinomais_treatment_forNot AvailablePMC13414665
hepatitisis_treatment_forNot AvailablePMC6273063
leukemiais_treatment_forNot AvailablePMC6273063
thyroid canceris_treatment_forNot AvailablePMC12401129
dermatitisassociated_withNot AvailablePMC10874124
anorexiaassociated_withNot AvailablePMC10874124
botulismassociated_withNot AvailablePMC10802438
influenzais_treatment_forNot AvailablePMC6273063
head and neck canceris_treatment_forNot AvailablePMC13096271
Exposure Sources
Source IDSourceSectorReference
494Food contact materialsFood, food processing & cookwareNot Available
495CeilingsBuilding & ConstructionNot Available
496FencingBuilding & ConstructionNot Available
497FloorsBuilding & ConstructionNot Available
498LaddersBuilding & ConstructionNot Available
499RoofsBuilding & ConstructionNot Available
500Stairs And RampsBuilding & ConstructionNot Available
503Tents Or CanopiesBuilding & ConstructionNot Available
504Adjustable ResistorsElectrical & Electronic EquipmentNot Available
505AmplifiersElectrical & Electronic EquipmentNot Available
506AntennasElectrical & Electronic EquipmentNot Available
507Auxiliary DevicesElectrical & Electronic EquipmentNot Available
508CoilsElectrical & Electronic EquipmentNot Available
509Colour Television SystemsElectrical & Electronic EquipmentNot Available
510Communication Cables Or ConductorsElectrical & Electronic EquipmentNot Available
512ContactsElectrical & Electronic EquipmentNot Available
513Cores Yokes Or ArmaturesElectrical & Electronic EquipmentNot Available
515Discharge Tubes With Liquid Pool CathodesElectrical & Electronic EquipmentNot Available
516Electric Hearing AidsElectrical & Electronic EquipmentNot Available
520Emergency Protective DevicesElectrical & Electronic EquipmentNot Available
523Gas Filled Discharge Tubes With Solid CathodeElectrical & Electronic EquipmentNot Available
525Line Transmission SystemsElectrical & Electronic EquipmentNot Available
526LoudspeakersElectrical & Electronic EquipmentNot Available
527MagnetsElectrical & Electronic EquipmentNot Available
528MicrophonesElectrical & Electronic EquipmentNot Available
529Power CablesElectrical & Electronic EquipmentNot Available
531RelaysElectrical & Electronic EquipmentNot Available
533Sparking PlugsElectrical & Electronic EquipmentNot Available
534Still Video CamerasElectrical & Electronic EquipmentNot Available
535Superconducting Magnets And Superconducting CoilsElectrical & Electronic EquipmentNot Available
536Superconductive Or Hyperconductive Conductors Cables Or Transmission LinesElectrical & Electronic EquipmentNot Available
538Thin Magnetic FilmsElectrical & Electronic EquipmentNot Available
539Video GamesElectrical & Electronic EquipmentNot Available
540X Ray TubesElectrical & Electronic EquipmentNot Available
551Processing FishFood, food processing & cookwareNot Available
553Treatment Of HopsFood, food processing & cookwareNot Available
554Ash TraysHousehold cleaning & consumer productsNot Available
559Non Electric Simulated Smoking DevicesHousehold cleaning & consumer productsNot Available
560Other Smoking RequisitesHousehold cleaning & consumer productsNot Available
562Pipe AccessoriesHousehold cleaning & consumer productsNot Available
566Tobacco PipesHousehold cleaning & consumer productsNot Available
570BadgesHousehold itemsNot Available
572Credit Card HoldersHousehold itemsNot Available
573Key RingsHousehold itemsNot Available
577Watch ChainsHousehold itemsNot Available
578Making CigarsIndustrial manufacturing & chemical processingNot Available
579Manufacture Of Iron Or SteelIndustrial manufacturing & chemical processingNot Available
583Anchoring EquipmentMarine, shipping & aquacultureNot Available
584BuoysMarine, shipping & aquacultureNot Available
589Life BuoysMarine, shipping & aquacultureNot Available
592Marine Propulsion Or SteeringMarine, shipping & aquacultureNot Available
593Nautical InstrumentsMarine, shipping & aquacultureNot Available
594Ship HullsMarine, shipping & aquacultureNot Available
597ChemosterilantsAgriculture & land managementNot Available
598Fertiliser DistributorsAgriculture & land managementNot Available
601Lawn MowersAgriculture & land managementNot Available
612Body Washing Or Cleaning ImplementsPersonal care & cosmeticsNot Available
616Face Mask CosmeticsPersonal care & cosmeticsNot Available
619Manicure PedicurePersonal care & cosmeticsNot Available
620Card GamesRecreation & sports surfacesNot Available
625Racing SportsRecreation & sports surfacesNot Available
629SwingsRecreation & sports surfacesNot Available
631Anthraquinone DyesTextiles, leather & furnishingsNot Available
634BucklesTextiles, leather & furnishingsNot Available
635ButtonsTextiles, leather & furnishingsNot Available
638Decorating TextilesTextiles, leather & furnishingsNot Available
640Embroidering And TuftingTextiles, leather & furnishingsNot Available
647Multicolour DyeingTextiles, leather & furnishingsNot Available
653SewingTextiles, leather & furnishingsNot Available
655Slide FastenersTextiles, leather & furnishingsNot Available
658Touch FastenersTextiles, leather & furnishingsNot Available
661UmbrellasTextiles, leather & furnishingsNot Available
663Sanitary EquipmentWastewater, sanitation & biosolidsNot Available
Pathways
0 pathways

No pathways found

No metabolic pathways have been associated with this synthetic chemical

Targets
StructureProteinUniProt IDOrganismRelationshipDetails
No targets found for this compound.
Concentrations
Not Available
External Links
DrugBank IDNot Available
HMDB IDHMDB0002386
FooDB IDFDB003575
Phenol Explorer IDNot Available
KNApSAcK IDC00000601
BiGG IDNot Available
BioCyc IDNot Available
METLIN IDNot Available
PDB IDNot Available
Wikipedia LinkBoron
Chemspider ID4574026
ChEBI ID30168
PubChem Compound ID5460517
Kegg Compound IDC06266
YMDB IDNot Available
ECMDB IDNot Available
References
Synthesis ReferenceNot Available
MSDSNot Available
General References
1. Semaghiul Birghila, Simona Dobrinas, Gabriela Stanciu and Alina Soceanu. Determination of major and minor elements in milk through ICP-AES. Environmental Engineering and Management Journal. November/December 2008, Vol.7, No.6, 805-808
2. Underwood, E.J. Trace elements in human and animal nutrition. Academic Press, New York, NY. p. 436 (1977).
3. A. Foroutan et al. The Chemical Composition of Commercial Cow's Milk (in preparation)
4. Š. ZAMBERLIN et al.: Mineral elements in milk and dairy products, Mljekarstvo 62 (2), 111-125
5. Hunt CD, Butte NF, Johnson LK: Boron concentrations in milk from mothers of exclusively breast-fed healthy full-term infants are stable during the first four months of lactation. J Nutr. 2005 Oct;135(10):2383-6.
6. Devirian TA, Volpe SL: The physiological effects of dietary boron. Crit Rev Food Sci Nutr. 2003;43(2):219-31.
7. Nielsen FH, Penland JG: Boron deprivation alters rat behaviour and brain mineral composition differently when fish oil instead of safflower oil is the diet fat source. Nutr Neurosci. 2006 Feb-Apr;9(1-2):105-12.