6-Mercaptopurine (CED0002313)

6-Mercaptopurine is an organic compound with the formula C5H4N4S and an average molecular weight of 152.18 g/mol. 6-Mercaptopurine belongs to the purines and purine derivatives, a subclass of imidazopyrimidines within the organic compounds. The compound is found in or released from 15 recorded sources. These include healthcare, pharmaceuticals, and veterinary products, specifically antineoplastic agents and drugs for obstructive airway diseases. It is also associated with electrical and electronic equipment, such as amplifiers, antennas, coils, electric hearing aids, and line transmission systems, among three others. Other sources include food, food processing, and cookware, specifically the processing of fish and meats, as well as building and construction materials like ceilings. Additionally, it is found in household items such as credit card holders and household cleaning and consumer products, including soap dispensers. The recorded route of exposure for this compound is oral. Biologically, 6-Mercaptopurine acts on four recorded protein targets. It functions as an inhibitor of hypoxanthine-guanine phosphoribosyltransferase (HPRT1), amidophosphoribosyltransferase (PPAT), inosine-5'-monophosphate dehydrogenase 1 (IMPDH1), and inosine-5'-monophosphate dehydrogenase 2 (IMPDH2).