Primidone (CED0004613)

Primidone is an organic compound with the formula C12H14N2O2 and an average molecular weight of 218.25 g/mol. Primidone belongs to the pyrimidines and pyrimidine derivatives, a subclass of diazines within the organic compounds. The compound is found in or released from 22 recorded sources. Within healthcare, pharmaceuticals, and veterinary products, it is identified as an antiepileptic, as well as a hypnotic and sedative. Other sources include food processing and cookware, specifically in food preservation and the preparation of wine or sparkling wine, and drinking water and water supply. It is also associated with building and construction materials such as floors. Additionally, it is found in household cleaning and consumer products—including soap detergents, perfumes within detergents and soaps, cigar cigarettes, other smoking requisites, and non-electric simulated smoking devices—as well as electrical and electronic equipment, including electric switches, antennas, electric hearing aids, conductors or conductive bodies characterized by the conductive materials, and electrically stimulated smoking devices. The recorded exposure route for the compound is oral. Primidone interacts with 20 recorded protein targets. It acts as an antagonist or positive allosteric modulator of the Gamma-aminobutyric acid receptor subunit alpha-1 (GABRA1), Gamma-aminobutyric acid receptor subunit alpha-2 (GABRA2), Gamma-aminobutyric acid receptor subunit alpha-3 (GABRA3), and Gamma-aminobutyric acid receptor subunit alpha-4 (GABRA4), among 16 other proteins.