Bisacodyl (CED0005548)

Bisacodyl is an organic compound with the chemical formula C22H19NO4 and an average molecular weight of 361.39 g/mol. Bisacodyl belongs to the diphenylmethanes, a subclass of benzene and substituted derivatives within the organic compounds. The compound is found in or released from 42 recorded sources. Within healthcare, pharmaceuticals, and veterinary products, it is used as a drug for constipation. Other recorded sources include building and construction materials such as tents or canopies, ladders, roofs, fencing, and stairs and ramps. It is associated with food, food processing, and cookware, specifically in the preparation of vinegar, food preservation, processing meats, and fermentation processes for beer. Additionally, it is found in household items like watch chains and badges, as well as household cleaning and consumer products including ash trays, other smoking requisites, devices for igniting matches, non electric simulated smoking devices, and cigar cigarettes. It is also released from electrical and electronic equipment, including antennas, amplifiers, adjustable resistors, auxiliary devices, and conductors or conductive bodies characterised by the conductive materials, among 17 other sources. Recorded exposure routes for the compound include oral, rectal, and topical. Bisacodyl interacts with nine recorded protein targets. It acts as an inhibitor or negative modulator of Aquaporin-3 (AQP3), Sodium/potassium-transporting ATPase subunit alpha-1 (ATP1A1), Sodium/potassium-transporting ATPase subunit beta-1 (ATP1B1), and Sodium/potassium-transporting ATPase subunit alpha-3 (ATP1A3), along with five other proteins.