Candesartan (CED0002684)

Candesartan is an organic compound with the chemical formula C24H20N6O3 and an average molecular weight of 440.45 g/mol. Candesartan belongs to the biphenyls and derivatives, a subclass of benzene and substituted derivatives within the organic compounds. In terms of biological activity, it is recorded as an antagonist of the Type-1 angiotensin II receptor (AGTR1). The compound has been found in or released from 29 recorded sources across various sectors. These include aquatic systems and sediments, such as groundwater, surface water, seawater, and freshwater, as well as drinking water and water supply sources including tap water, bottled water, and desalinated water. It is also present in wastewater, sanitation, and biosolids, specifically within industrial wastewater, wastewater treatment effluent, mine wastewater, and unspecified wastewater. Additionally, candesartan is associated with electrical and electronic equipment, including electrodes, antennas, electrically stimulated smoking devices, and conductors or conductive bodies characterised by the conductive materials. Household cleaning and consumer products, such as tobacco smoke filters, cigar cigarettes, non electric simulated smoking devices, and other smoking requisites, are also identified sources. Furthermore, it is found in appliances, HVAC, and refrigerants, specifically in water heaters and water coolers, along with six additional sectors. Recorded routes of exposure for this compound include oral, inhalation, and touch.