Nisoldipine (CED0006717)

Nisoldipine is an organic compound with the formula C20H24N2O6 and an average molecular weight of 388.41 g/mol. Nisoldipine belongs to the hydropyridines, a subclass of pyridines and derivatives within the organic compounds. It is categorized as an organoheterocyclic compound. The compound is found in or released from 16 recorded sources. These include healthcare, pharmaceuticals, and veterinary products, specifically as calcium channel blockers, as well as food preservation within the food, food processing, and cookware category. Other recorded sources include household cleaning and consumer products—such as bleaching agents, perfumes within detergents and soaps, cigar cigarettes, other smoking requisites, and tobacco smoke filters—and electrical and electronic equipment, including amplifiers, antennas, electric switches, adjustable resistors, and conductors or conductive bodies characterised by the conductive materials. The recorded exposure route for this compound is oral. Nisoldipine interacts with five recorded protein targets. It acts as an inhibitor of the voltage-dependent L-type calcium channel subunit alpha-1D (CACNA1D), voltage-dependent L-type calcium channel subunit alpha-1S (CACNA1S), and voltage-dependent L-type calcium channel subunit alpha-1C (CACNA1C). Additionally, it targets the voltage-dependent calcium channel subunit alpha-2/delta-1 (CACNA2D1) and one other protein.