Phentolamine (CED0003496)

Phentolamine is an organic compound with the chemical formula C17H19N3O and an average molecular weight of 281.35 g/mol. Phentolamine belongs to the amines, a subclass of organonitrogen compounds within the organic compounds. The compound is associated with ten recorded sources. Within healthcare, pharmaceuticals, and veterinary products, it is found in peripheral vasodilators and unclassified therapeutic products. It is also present in food preservation within food, food processing, and cookware. Other sources include electrical and electronic equipment, such as radio transmission systems, antennas, and electrically stimulated smoking devices, as well as household cleaning and consumer products, including tobacco smoke filters, cigar cigarettes, other smoking requisites, and non electric simulated smoking devices. Recorded exposure routes for phentolamine include intravenous, intramuscular, parenteral, submucosal, and ophthalmic administration. At the molecular level, phentolamine interacts with eight recorded protein targets. It functions as an antagonist/blocker of the Alpha-1A adrenergic receptor (ADRA1A), Alpha-1B adrenergic receptor (ADRA1B), Alpha-1D adrenergic receptor (ADRA1D), and Alpha-2A adrenergic receptor (ADRA2A), in addition to four other proteins.