Sulfadoxine (CED0003027)

Sulfadoxine is an organic compound with the chemical formula C12H14N4O4S and an average molecular weight of 310.33 g/mol. Sulfadoxine belongs to the benzenesulfonamides, a subclass of benzene and substituted derivatives within the organic compounds. The compound is associated with 12 recorded sources. Within healthcare, pharmaceuticals, and veterinary products, it is found in antibiotics, antiprotozoals, and gynecologicals. It is also released from household cleaning and consumer products, including tobacco smoke filters, other smoking requisites, and non electric simulated smoking devices. Additionally, it is found in drinking water and water supply, as well as electrical and electronic equipment such as radio transmission systems, antennas, video games, auxiliary devices, and electrically stimulated smoking devices. Recorded routes of exposure include oral and inhalation. At the molecular level, sulfadoxine interacts with four recorded protein targets. It acts as a binder or inhibitor of dihydropteroate synthase and specifically targets dihydropteroate synthase (folP). Other recorded protein targets include amine oxidase [flavin-containing] B (MAOB) and bifunctional dihydrofolate reductase-thymidylate synthase.