Terbinafine (CED0003452)

Terbinafine is an organic compound with the chemical formula C21H25N and an average molecular weight of 291.43 g/mol. Terbinafine belongs to the naphthalenes, a class of benzenoids within the organic compounds. This compound has been identified in or released from 31 recorded sources across multiple sectors. These include aquatic systems and sediments, such as seawater, freshwater, surface water, and groundwater, as well as drinking water and water supply sources including bottled water, tap water, desalinated water, and drinking water. It is also found in wastewater, sanitation, and biosolids, specifically in wastewater, industrial wastewater, mine wastewater, and wastewater treatment effluent. Additional sources include marine, shipping, and aquaculture sectors, specifically bilge water and ballast water, and appliances, HVAC, and refrigerants, such as water heaters and water coolers. Furthermore, it is associated with electrical and electronic equipment, including antennas, adjustable resistors, communication cables or conductors, auxiliary devices, electric hearing aids, and three other sources, along with six additional sectors. Recorded routes of exposure for terbinafine include touch, topical, oral, and inhalation. At the molecular level, terbinafine is associated with two recorded protein targets. It acts as an inhibitor of squalene monooxygenase (SQLE) and targets squalene epoxidase ERG1.