Valsartan (CED0002052)

Valsartan is an organic compound with the formula $\text{C}_{24}\text{H}_{29}\text{N}_5\text{O}_3$ and an average molecular weight of 435.53 g/mol. Valsartan belongs to the amino acids, peptides, and analogues, a subclass of carboxylic acids and derivatives within the organic compounds. It acts as an antagonist of the Type-1 angiotensin II receptor (AGTR1). The compound is used as a treatment for essential hypertension (PMC4559490), hypertension (PMC7175553), coronary artery disease (PMC7175553), myocardial infarction (PMC7175553), and atrial fibrillation (PMC7175553). Conversely, it is associated with an increase in myocardial infarction (PMC7175553). Valsartan has been found in or released from 60 recorded sources. These include drinking water and water supply sources such as bottled water, tap water, desalinated water, and drinking water, as well as aquatic systems and sediments including freshwater, seawater, surface water, and groundwater. Other sources include food, food processing and cookware—specifically the processing of meats, processing of fish, preparation of malt, preparation of wine or sparkling wine, and fermentation processes for beer—and household cleaning and consumer products such as bleaching agents, ash trays, other smoking requisites, non electric simulated smoking devices, and cigar cigarettes. It is also found in building and construction materials, including floors, ceilings, fencing, ladders, and waterproofing sprays, and electrical and electronic equipment, including antennas, amplifiers, coils, auxiliary devices, and colour television systems, among 14 more. Recorded routes of exposure include touch, oral, and inhalation.