Silybin (CED0004595)

Silybin is an organic compound with the formula C25H22O10 and an average molecular weight of 482.44 g/mol. Silybin belongs to the flavonolignans, a class of lignans, neolignans and related compounds within the organic compounds. In biological contexts, the compound acts as an antioxidant (PMC10975324, PMC2767273) and an iron chelator (PMC12630495). It serves as an inhibitor of the protein Polyunsaturated fatty acid 5-lipoxygenase (ALOX5) and has a therapeutic effect on inflammation (PMC9117022). Industrially, silybin is utilized as a softener and conditioner. The compound is found in or released from 20 recorded sources across several sectors. These include healthcare, pharmaceuticals and veterinary products via medical devices; energy, oil and gas through lubricants; and textiles, leather and furnishings, specifically carpets, rugs, and synthetic textiles. It is also present in household cleaning and consumer products, such as soap detergents, tobacco smoke filters, and perfumes within detergents and soaps. Within the food, food processing and cookware sector, it is associated with food preservation, food packaging, the preparation of vinegar, and fermentation processes for beer. Additionally, it is found in electrical and electronic equipment, including batteries, capacitors, printed circuit boards, cell phones, and wires and cables, among two other sectors. Recorded exposure routes for silybin include oral, inhalation, and touch.