Captopril (CED0002053)

Captopril (C9H15NO3S) is an organic compound with an average molecular weight of 217.28 g/mol. Captopril belongs to the amino acids, peptides, and analogues, a subclass of carboxylic acids and derivatives within the organic compounds. It is used as a biological antioxidant (PMC12841722) and is classified as an ACE inhibitor. Recorded exposure routes for this compound include oral administration. Captopril is found in or released from 15 recorded sources, including healthcare, pharmaceuticals & veterinary products; food, food processing & cookware, such as the preparation of wine or sparkling wine and the preparation of vinegar; household cleaning & consumer products, including other smoking requisites, non electric simulated smoking devices, and cigar cigarettes; and electrical & electronic equipment, including electric switches, electric hearing aids, communication cables or conductors, auxiliary devices, and antennas. The compound interacts with five recorded protein targets, serving as an activator or inhibitor of Angiotensin-converting enzyme (ACE), as well as Leukotriene A-4 hydrolase (LTA4H), Matrix metalloproteinase-9 (MMP9), and 72 kDa type IV collagenase (MMP2). Regarding health effects, Captopril is used as a treatment for hypertension (PMC10888711, PMC9265340, PMC9505973) and chronic kidney disease (PMC12067445). Additionally, it has a therapeutic effect on heart failure (PMC12841722).