cAMP (CED0000595)

Record Information
Version1.0
Creation Date2016-05-22 04:27:14 UTC
Update Date2026-08-17 23:40:49 UTC
Accession NumberCHEM017544
Identification
Common NamecAMP
ClassSmall Molecule
Description
cAMP is an organic compound with the formula C10H12N5O6P and an average molecular weight of 329.21 g/mol. cAMP belongs to the cyclic purine nucleotides, a subclass of purine nucleotides within the organic compounds. This compound is categorized under the superclass of nucleosides, nucleotides, and analogues. In industrial applications, cAMP is utilized as a softener and conditioner. It has been identified in 12 recorded sources. Within the category of electrical and electronic equipment, it is found in amplifiers, antennas, communication cables or conductors, discharge lamps, and conductors or conductive bodies characterised by the conductive materials, among two other sources. It is also associated with food, food processing and cookware, specifically in food preservation, the preparation of vinegar, the preparation of wine or sparkling wine, and fermentation processes for beer. Additionally, it is found in household cleaning and consumer products, specifically in tobacco smoke filters. cAMP interacts with six recorded protein targets. These include the cAMP-dependent protein kinase type I-alpha regulatory subunit (PRKAR1A), the cAMP-dependent protein kinase type II-beta regulatory subunit (PRKAR2B), the potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (HCN2), and the DNA-binding transcriptional dual regulator CRP (crp), as well as two other proteins.
Contaminant TypeNot Available
Chemical Structure
Synonyms
ValueSource
Adenosine 3',5'-cyclic monophosphateChEBI
Adenosine 3',5'-cyclic phosphateChEBI
Adenosine 3',5'-phosphateChEBI
ADENOSINE-3',5'-cyclic-monophosphATEChEBI
CAMPChEBI
Cyclic adenylic acidChEBI
Adenosine 3',5'-cyclic monophosphoric acidGenerator
Adenosine 3',5'-cyclic phosphoric acidGenerator
Adenosine 3',5'-phosphoric acidGenerator
ADENOSINE-3',5'-cyclic-monophosphoric acidGenerator
Cyclic adenylateGenerator
Cyclic AMP, sodium saltMeSH
3',5'-monoPhosphate, adenosine cyclicMeSH
Adenosine cyclic monophosphateMeSH
Adenosine cyclic-3',5'-monophosphateMeSH
Cyclic AMP, monopotassium saltMeSH
monoPhosphate, adenosine cyclicMeSH
AMP, CyclicMeSH
Adenosine cyclic 3',5'-monophosphateMeSH
Adenosine cyclic 3,5 monophosphateMeSH
Cyclic 3',5'-monophosphate, adenosineMeSH
Cyclic AMP, (R)-isomerMeSH
Cyclic AMP, monoammonium saltMeSH
Cyclic AMP, monosodium saltMeSH
Cyclic monophosphate, adenosineMeSH
Adenosine cyclic 3',5' monophosphateMeSH
Cyclic AMP, disodium saltMeSH
Cyclic-3',5'-monophosphate, adenosineMeSH
3'5'-Cyclic AMPHMDB
6-(6-amino-9H-Purin-9-yl)tetrahydro-4H-furo[3,2-D][1,3,2]dioxaphosphinine-2,7-diol 2-oxideHMDB
AcrasinHMDB
Adenosine 3',5'-cyclophosphateHMDB
Adenosine 3',5'-monophosphateHMDB
Adenosine 3,5'-cyclic monophosphorateHMDB
Adenosine 3,5'-cyclic monophosphoric acidHMDB
Adenosine cyclic-monophosphateHMDB
Adenosine-cyclic-phosphateHMDB
Adenosine-cyclic-phosphoric-acidHMDB
Cyclic 3',5'-adenylateHMDB
Cyclic 3',5'-adenylic acidHMDB
Cyclic 3',5'-AMPHMDB
Cyclic adenosine 3',5'-phosphateHMDB
Cyclic AMPChEBI
Chemical FormulaC10H12N5O6P
Average Molecular Mass329.206 g/mol
Monoisotopic Mass329.053 g/mol
CAS Registry Number60-92-4
IUPAC Name(4aR,6R,7R,7aS)-6-(6-amino-9H-purin-9-yl)-2,7-dihydroxy-hexahydro-2lambda5-furo[3,2-d][1,3,2]dioxaphosphinin-2-one
Traditional Name(4aR,6R,7R,7aS)-6-(6-aminopurin-9-yl)-2,7-dihydroxy-tetrahydro-4H-2lambda5-furo[3,2-d][1,3,2]dioxaphosphinin-2-one
SMILESNC1=NC=NC2=C1N=CN2[C@@H]1O[C@@H]2COP(O)(=O)O[C@H]2[C@H]1O
InChI IdentifierInChI=1S/C10H12N5O6P/c11-8-5-9(13-2-12-8)15(3-14-5)10-6(16)7-4(20-10)1-19-22(17,18)21-7/h2-4,6-7,10,16H,1H2,(H,17,18)(H2,11,12,13)/t4-,6-,7-,10-/m1/s1
InChI KeyIVOMOUWHDPKRLL-KQYNXXCUSA-N
Chemical Taxonomy
Description Belongs to the class of organic compounds known as 3',5'-cyclic purine nucleotides. These are purine nucleotides in which the oxygen atoms linked to the C3 and C5 carbon atoms of the ribose moiety are both bonded the same phosphorus atom of the phosphate group.
KingdomOrganic compounds
Super ClassNucleosides, nucleotides, and analogues
ClassPurine nucleotides
Sub ClassCyclic purine nucleotides
Direct Parent3',5'-cyclic purine nucleotides
Alternative Parents
Substituents
  • 3',5'-cyclic purine ribonucleotide
  • Pentose phosphate
  • Glycosyl compound
  • N-glycosyl compound
  • 6-aminopurine
  • Monosaccharide phosphate
  • Purine
  • Imidazopyrimidine
  • Aminopyrimidine
  • Organic phosphoric acid derivative
  • N-substituted imidazole
  • Monosaccharide
  • Pyrimidine
  • Imidolactam
  • Imidazole
  • Azole
  • Tetrahydrofuran
  • Heteroaromatic compound
  • Secondary alcohol
  • Oxacycle
  • Azacycle
  • Organoheterocyclic compound
  • Alcohol
  • Organic oxygen compound
  • Organic nitrogen compound
  • Hydrocarbon derivative
  • Organic oxide
  • Organopnictogen compound
  • Amine
  • Primary amine
  • Organooxygen compound
  • Organonitrogen compound
  • Aromatic heteropolycyclic compound
Molecular FrameworkAromatic heteropolycyclic compounds
External Descriptors
Biological Properties
StatusDetected and Not Quantified
OriginNot Available
Cellular LocationsNot Available
Biofluid LocationsNot Available
Tissue LocationsNot Available
ApplicationsNot Available
Biological RolesNot Available
Chemical RolesNot Available
Organoleptic EffectsNot Available
Physical Properties
StateNot Available
AppearanceNot Available
Experimental Properties
PropertyValue
Melting PointNot Available
Boiling PointNot Available
SolubilityNot Available
Predicted Properties
PropertyValueSource
Water Solubility3.58 g/LALOGPS
logP-2.3ALOGPS
logP-3.4ChemAxon
logS-2ALOGPS
pKa (Strongest Acidic)1.83ChemAxon
pKa (Strongest Basic)3.92ChemAxon
Physiological Charge-1ChemAxon
Hydrogen Acceptor Count8ChemAxon
Hydrogen Donor Count3ChemAxon
Polar Surface Area154.84 ŲChemAxon
Rotatable Bond Count1ChemAxon
Refractivity70.29 m³·mol⁻¹ChemAxon
Polarizability28.42 ųChemAxon
Number of Rings4ChemAxon
BioavailabilityYesChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon
Spectra
Spectra
Spectrum TypeDescriptionSplash KeyDeposition DateView
GC-MSGC-MS Spectrumsplash10-00di-9761000000-ed8f1fea0ef2e7b43ff8Not AvailableView Spectrum
GC-MSGC-MS Spectrumsplash10-03du-2971000000-c0200940e0e88308fbdeNot AvailableView Spectrum
GC-MSGC-MS Spectrumsplash10-00di-9761000000-ed8f1fea0ef2e7b43ff8Not AvailableView Spectrum
GC-MSGC-MS Spectrumsplash10-03du-2971000000-c0200940e0e88308fbdeNot AvailableView Spectrum
Predicted GC-MSPredicted GC-MS Spectrumsplash10-0fbl-3901000000-b95501fad426dc61082fNot AvailableView Spectrum
Predicted GC-MSPredicted GC-MS Spectrumsplash10-03y0-3922000000-7e84eb99b8248254daa6Not AvailableView Spectrum
Predicted GC-MSPredicted GC-MS SpectrumNot AvailableNot AvailableView Spectrum
Predicted GC-MSPredicted GC-MS SpectrumNot AvailableNot AvailableView Spectrum
Predicted GC-MSPredicted GC-MS SpectrumNot AvailableNot AvailableView Spectrum
Predicted GC-MSPredicted GC-MS SpectrumNot AvailableNot AvailableView Spectrum
Predicted GC-MSPredicted GC-MS SpectrumNot AvailableNot AvailableView Spectrum
Predicted GC-MSPredicted GC-MS SpectrumNot AvailableNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-004i-0009000000-02ee7f342f5c1bada389Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-004i-0009000000-a00a2165c3d37c4e1ef2Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-004i-0109000000-7f48145f84828c2bbd5dNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-001i-0119000000-d94a34a13521ae3d4692Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0900000000-f10e1d70e30865424af6Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-03dr-0629000000-bf4ec1094b7991c3633cNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-03dr-0629000000-9736faaf70ec79d5bd03Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-001i-0109000000-6bf3784f4b710ce04a3eNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-03dr-0629000000-3f5ea9ba1508e359ad80Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-03dr-0519000000-059e8569ee179529bf21Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-001i-0009000000-88dad10a362b1088849eNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-004i-0509004000-bb02289fcd39ac1a203cNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0a4i-1900000000-da49323734f24bf724d6Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-001i-0900000000-a4e60131f41413b6fecfNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-004i-0009000000-98ee4e70689c06adc603Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-056r-0409005001-97fd793d1d14a84c3530Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0a4i-0900000000-1f2045ac2ff736aa80a2Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-001i-0900000000-8bbb24702fa6ccd76268Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-004i-0009000000-6d23df7535894180e6dfNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-001i-0009000000-c527aad341e122fc9beaNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-001i-0209000000-1bb2d660cc00c85a808fNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-003r-2904000000-865c1b989665f73ac3f4Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0a4i-1900000000-da49323734f24bf724d6Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-001i-0900000000-fb88b0e6d5a3bb266f1fNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-004i-0009000000-98ee4e70689c06adc603Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0a4i-0900000000-1f2045ac2ff736aa80a2Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-001i-0900000000-8bbb24702fa6ccd76268Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-004i-0009000000-6d23df7535894180e6dfNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-003r-2904000000-865c1b989665f73ac3f4Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0900000000-f10e1d70e30865424af6Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-03dr-0629000000-bf4ec1094b7991c3633cNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-03dr-0629000000-9736faaf70ec79d5bd03Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-03dr-0629000000-b87e6e72322b6871c8c4Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-03dr-0519000000-059e8569ee179529bf21Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-001i-0009000000-88dad10a362b1088849eNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-001i-0009000000-c527aad341e122fc9beaNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-001i-0209000000-1bb2d660cc00c85a808fNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-001i-0209000000-55cd6fc055fc945ef516Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0019-0906000000-24477b68bb111a1da20aNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-000i-1900000000-fd1075c4672c9d1aa0afNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0019-1915000000-822999ee9e9ad9d0c492Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-000i-1900000000-2e3df0b9191216ad6321Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-000i-4900000000-93b8fd3c2a90fff2bb1fNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0019-1915000000-2218587cf6e8dfbfc96fNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-000i-4900000000-3fa3b4672f1b9296fa83Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-001i-0309000000-55cd6fc055fc945ef516Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-001i-0109000000-4480ee79a6f778e4dd20Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-000i-0911000000-e8653f2d5eea70d6e984Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-003r-6900000000-e51e79fcb2d8152ca47cNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-001i-0109000000-4c2745a8ae87ffe01dc7Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-000i-1900000000-7be6558d72771c6716bdNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-000i-1900000000-9cf64a50cb4bbe797c1eNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-000i-0902000000-3f9200f1122785e91589Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-000i-0902000000-ce3865e841a4e6bfa31bNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-000i-0902000000-cd1b90734bc5e7e56048Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-003r-2903000000-c7469d67bec73bab9157Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-003r-2903000000-d2c36703c654e76e8817Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-003r-1902000000-7ad446836f097a131f93Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-004i-0109000000-51b542b314fb8d354428Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-004i-0109000000-891909d94f39ed87cfbdNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-003r-1902000000-03ed23baaa37ce0aa35aNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-003r-4900000000-e8dc6de63271368c3edaNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0059-0609000000-e7b4e02057a014f67629Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-000i-0902000000-1bedd17480e0662a68a8Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-001i-3900000000-d348cd10af065959f418Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-000i-0902000000-8b2cad217eb3ffdccccaNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-000i-0902000000-be2e4ac44141fe2fe12fNot AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-000i-0904000000-f37dad1d4334840eb74eNot AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-000i-0900000000-8b2624b0c421f5f77e8eNot AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-000i-1900000000-3052962b6de42b1e2f5dNot AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-0059-1709000000-5a8b1290a24ec7280b33Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-001i-2900000000-ed24096ac59b92b5ebb8Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-001i-9800000000-f2f527529235506fb81eNot AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-0019-0908000000-72d54e9adf34ea205502Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-000i-0900000000-67cf203fd0900237248eNot AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-000i-1900000000-1cefc011d546d05188f4Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-004i-0009000000-24546b3fc8282cbfee15Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-004i-2914000000-561a5c07629901716815Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-001i-3901000000-0ea4ecc0d4b48f37548dNot AvailableView Spectrum
1D NMR1H NMR Spectrum (1D, D2O, predicted)Not AvailableNot AvailableView Spectrum
1D NMR13C NMR Spectrum (1D, D2O, predicted)Not AvailableNot AvailableView Spectrum
Toxicity Profile
Mechanism of ToxicityNot Available
Carcinogenicity (IARC Classification)Not Available
Minimum Risk LevelNot Available
SymptomsNot Available
TreatmentNot Available
Toxicity Values
Toxicity ValueUnitValue RangeOrganismDose DescriptorRoute of ExposurePredicted or ExperimentalReference
2483.0Log mg/kg[1400:4400]RatLD50oralpredictedNot Available
Health Effects
Health EffectRelationshipDirectionReference
Exposure Sources
Source IDSourceSectorReference
10InsecticidesAgriculture & land managementNot Available
505AmplifiersElectrical & Electronic EquipmentNot Available
506AntennasElectrical & Electronic EquipmentNot Available
510Communication Cables Or ConductorsElectrical & Electronic EquipmentNot Available
511Conductors Or Conductive Bodies Characterised By The Conductive MaterialsElectrical & Electronic EquipmentNot Available
514Discharge LampsElectrical & Electronic EquipmentNot Available
529Power CablesElectrical & Electronic EquipmentNot Available
537Television SystemsElectrical & Electronic EquipmentNot Available
544Fermentation Processes For BeerFood, food processing & cookwareNot Available
545Food PreservationFood, food processing & cookwareNot Available
548Preparation Of VinegarFood, food processing & cookwareNot Available
549Preparation Of Wine Or Sparkling WineFood, food processing & cookwareNot Available
569Tobacco Smoke FiltersHousehold cleaning & consumer productsNot Available
580Manufacture Preparation Of Tobacco ProductsIndustrial manufacturing & chemical processingNot Available
600Herbicides And AlgicidesAgriculture & land managementNot Available
605Pest RepellantsAgriculture & land managementNot Available
606Plant Growth RegulatorsAgriculture & land managementNot Available
610Aftersun ProductsPersonal care & cosmeticsNot Available
611Anti Perspirants Or Body DeoderantsPersonal care & cosmeticsNot Available
613DepilatoriesPersonal care & cosmeticsNot Available
614Essential Oils Or PerfumesPersonal care & cosmeticsNot Available
615Eye Makeup ProductsPersonal care & cosmeticsNot Available
617Lip Care ProductsPersonal care & cosmeticsNot Available
618Lip Makeup ProductsPersonal care & cosmeticsNot Available
632ApparelTextiles, leather & furnishingsNot Available
650Purses Luggage Hand BagsTextiles, leather & furnishingsNot Available
Pathways
356 pathways
Targets
StructureProteinUniProt IDOrganismRelationshipDetails
Click to view 3D structureCyclic di-GMP phosphodiesterase RocRQ9HX69Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228)Predicted (SEA)1.55698
Click to view 3D structureCyclic nucleotide-gated channel alpha-2Q00195Rattus norvegicusPredicted (SEA)0.0778492
Adenosylhomocysteinase structureClick to view 3D structureAdenosylhomocysteinaseP23526HumansPredicted (SEA)1.24559
Heat shock protein HSP 90-alpha structureClick to view 3D structureHeat shock protein HSP 90-alphaP07900HumansPredicted (SEA)6.77288
Endoplasmin structureClick to view 3D structureEndoplasminP14625HumansPredicted (SEA)4.5931
Click to view 3D structureAdenosine receptor A3P28647Rattus norvegicusPredicted (SEA)13.1565
Click to view 3D structureAdenosine receptor A1P25099Rattus norvegicusPredicted (SEA)21.4085
Adenosine receptor A3 structureClick to view 3D structureAdenosine receptor A3P0DMS8HumansPredicted (SEA)27.1694
Click to view 3D structureAdenosine receptor A2aP30543Rattus norvegicusPredicted (SEA)20.4743
Adenosine receptor A2a structureClick to view 3D structureAdenosine receptor A2aP29274HumansPredicted (SEA)25.4567
Click to view 3D structure2-oxoglutarate receptor 1Q6Y1R5Rattus norvegicusPredicted (SEA)2.88042
Adenosine receptor A1 structureClick to view 3D structureAdenosine receptor A1P30542HumansPredicted (SEA)25.0674
P2Y purinoceptor 1 structureClick to view 3D structureP2Y purinoceptor 1P47900HumansPredicted (SEA)9.03051
Click to view 3D structureP2Y purinoceptor 2P41231HumansPredicted (SEA)8.17417
Click to view 3D structureS-methyl-5'-thioadenosine phosphorylaseQ9CQ65Mus musculusPredicted (SEA)3.34752
Click to view 3D structureEndoplasminQ29092Sus scrofaPredicted (SEA)5.44945
Click to view 3D structureP2Y purinoceptor 1P49652Meleagris gallopavoPredicted (SEA)5.83869
Click to view 3D structureHeat shock cognate 71 kDa proteinP19120Bos taurusPredicted (SEA)5.13805
Click to view 3D structureSensor protein kinase WalKQ9RDT3Staphylococcus aureusPredicted (SEA)5.13805
P2X purinoceptor 1 structureClick to view 3D structureP2X purinoceptor 1P51575HumansPredicted (SEA)5.44945
Click to view 3D structureRyanodine receptorQ8TA74Hemicentrotus pulcherrimusPredicted (SEA)0.0778492
Click to view 3D structureAdenosylhomocysteinaseP10760Rattus norvegicusPredicted (SEA)1.08989
P2X purinoceptor 3 structureClick to view 3D structureP2X purinoceptor 3P56373HumansPredicted (SEA)5.52729
ADP-ribose glycohydrolase MACROD1 structureClick to view 3D structureADP-ribose glycohydrolase MACROD1Q9BQ69HumansPredicted (SEA)4.7488
ADP-ribose glycohydrolase MACROD2 structureClick to view 3D structureADP-ribose glycohydrolase MACROD2A1Z1Q3HumansPredicted (SEA)4.7488
Concentrations
Not Available
External Links
DrugBank IDDB02527
HMDB IDHMDB0000058
FooDB IDFDB001497
Phenol Explorer IDNot Available
KNApSAcK IDC00001497
BiGG ID1484809
BioCyc IDCAMP
METLIN ID5120
PDB IDNot Available
Wikipedia LinkCyclic_AMP
Chemspider ID5851
ChEBI ID17489
PubChem Compound ID6076
Kegg Compound IDC00575
YMDB IDYMDB00023
ECMDB IDECMDB00058
References
Synthesis ReferenceNot Available
MSDSNot Available
General References
1. Genieser, H. G.; Butt, E.; Bottin, U.; Dostmann, W.; Jastorff, B. Synthesis of the 3',5'-cyclic phosphates from unprotected nucleosides. Synthesis (1989), (1), 53-4.
2. Imashuku S, Todo S, Nakajima F: [Intra-aortic prostaglandin E1 infusion in the treatment of advanced neuroblastoma]. Gan To Kagaku Ryoho. 1983 Sep;10(9):1936-43.
3. Wine JJ, Joo NS: Submucosal glands and airway defense. Proc Am Thorac Soc. 2004;1(1):47-53.
4. Onali P, Strada SJ, Chang L, Epstein PM, Hersh EM, Thompson WJ: Purification and characterization of high-affinity cyclic adenosine 5'-monophosphate phosphodiesterases from human acute myelogenous leukemic cells. Cancer Res. 1985 Mar;45(3):1384-91.
5. Rademaker MT, Charles CJ, Lewis LK, Yandle TG, Cooper GJ, Coy DH, Richards AM, Nicholls MG: Beneficial hemodynamic and renal effects of adrenomedullin in an ovine model of heart failure. Circulation. 1997 Sep 16;96(6):1983-90.
6. Mashayekhi F, Aghahoseini F, Rezaie A, Zamani MJ, Khorasani R, Abdollahi M: Alteration of cyclic nucleotides levels and oxidative stress in saliva of human subjects with periodontitis. J Contemp Dent Pract. 2005 Nov 15;6(4):46-53.
7. Sugo T, Tachimoto H, Chikatsu T, Murakami Y, Kikukawa Y, Sato S, Kikuchi K, Nagi T, Harada M, Ogi K, Ebisawa M, Mori M: Identification of a lysophosphatidylserine receptor on mast cells. Biochem Biophys Res Commun. 2006 Mar 24;341(4):1078-87. Epub 2006 Jan 25.
8. Watanabe K, Beinborn M, Nagamatsu S, Ishida H, Takahashi S: Menetrier's disease in a patient with Helicobacter pylori infection is linked to elevated glucagon-like peptide-2 activity. Scand J Gastroenterol. 2005 Apr;40(4):477-81.
9. Naef A, Keller HU: A short transient increase in cyclic adenosine 3', 5'-monophosphate levels of neutrophil granulocytes following exposure to chemotactic factors. Adv Exp Med Biol. 1982;141:39-48.
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