Amiloride (CED0002203)

Amiloride is an organic compound with the formula C6H8ClN7O and an average molecular weight of 229.63 g/mol. Amiloride belongs to the pyrazines, a subclass of diazines within the organic compounds. It is classified as a biological drug (PMC10503410) and acts as a biological diuretic (PMC7845941). The compound is found in or released from nine recorded sources, including healthcare, pharmaceuticals, and veterinary products specifically as diuretics. Other recorded sources include electrical and electronic equipment such as antennas and electrically stimulated smoking devices, as well as household cleaning and consumer products including bleaching agents, cigar cigarettes, non electric simulated smoking devices, other smoking requisites, and tobacco pipes. The recorded exposure route for this compound is oral. Amiloride interacts with nine recorded protein targets. It acts as an inhibitor of the epithelial sodium channel subunit alpha (SCNN1A), the epithelial sodium channel subunit beta (SCNN1B), the acid-sensing ion channel 1 (ASIC1), and the copper-containing diamine oxidase (AOC1), among five other proteins.