Probucol (CED0004765)

Probucol belongs to the phenylpropanes, a subclass of benzene and substituted derivatives within the organic compounds. With an average molecular weight of 516.84 g/mol, Probucol is a heavy molecule with the chemical formula C31H48O2S2. It functions as a biological antioxidant (PMC13440557, PMC4271727, PMC5989656, PMC7648605). In terms of health effects, the compound is used as a treatment for coronary artery disease (PMC4271727) and has a therapeutic effect on atherosclerosis (PMC11086401). Its protein targets include Liver carboxylesterase 1 (CES1) and the Phospholipid-transporting ATPase ABCA1, which it inhibits. Probucol is found in or released from ten recorded sources. Within healthcare, pharmaceuticals, and veterinary products, it is utilized as a lipid modifying agent. It is also associated with food preservation and fermentation processes for beer. Other recorded sources include household cleaning and consumer products, such as perfumes within detergents and soaps, tobacco smoke filters, and non-electric simulated smoking devices. Additionally, it is linked to electrical and electronic equipment, specifically antennas, conductors or conductive bodies characterised by the conductive materials, electrodes, and electrically stimulated smoking devices. The recorded route of exposure for this compound is oral.