Andrographolide is an organoheterocyclic compound with the formula C20H30O5 and an average molecular weight of 350.45 g/mol. Andrographolide belongs to the gamma butyrolactones, a subclass of lactones within the organic compounds. It is recorded as being released from several sources, including amplifiers within electrical and electronic equipment, as well as household cleaning and consumer products such as pipe accessories, other smoking requisites, and non electric simulated smoking devices.
In industrial applications, the compound is used as a conditioner and softener. Biologically, it serves as an analgesic (PMC7285361) and an anti-inflammatory agent (PMC8069343). It has a therapeutic effect on inflammation (PMC11086401, PMC5695812). The compound interacts with five recorded protein targets, including interleukin-6 (IL6), tumor necrosis factor (TNF), nuclear factor NF-kappa-B p100 subunit (NFKB2), interleukin-1 beta (IL1B), and one other protein.
Belongs to the class of organic compounds known as gamma butyrolactones. Gamma butyrolactones are compounds containing a gamma butyrolactone moiety, which consists of an aliphatic five-member ring with four carbon atoms, one oxygen atom, and bears a ketone group on the carbon adjacent to the oxygen atom.
