Glycyrrhizin (CED0002518)

Glycyrrhizin (C42H62O16) is a chemical compound used industrially as a humectant, a softener and conditioner, and a flavouring and nutrient. Glycyrrhizin belongs to the terpene glycosides, a subclass of prenol lipids within the organic compounds. With an average molecular weight of 822.94 g/mol, Glycyrrhizin is a heavy molecule. The compound is found in or released from 24 recorded sources. Within healthcare, pharmaceuticals, and veterinary products, it is associated with lipotropics and liver therapy. Other sources include electrical and electronic equipment such as hybrid capacitors, video games, auxiliary devices, electrically stimulated smoking devices, and fixed capacitors and their manufacture. It is also present in household cleaning and consumer products, including pipe accessories, non electric simulated smoking devices, bleaching agents, cigar cigarettes, other smoking requisites, and four additional sources. Furthermore, it is found in food, food processing, and cookware, specifically in the preparation of vinegar, preparation of wine or sparkling wine, fermentation processes for beer, molasses and treatment of molasses, agglomerated sugar products, and four more. Recorded exposure routes include oral, dental, cutaneous, and topical. Glycyrrhizin interacts with six recorded protein targets. It acts as an antagonist/antagonist and functions as an inhibitor, inducer, or translocation inhibitor of 11-beta-hydroxysteroid dehydrogenase 1 (HSD11B1). Additionally, it targets the nuclear factor NF-kappa-B p105 subunit (NFKB1), tumor necrosis factor (TNF), caspase-3 (CASP3), and two other proteins.