Bretylium (CED0007238)

Bretylium is an organic compound with the formula C11H17BrN and an average molecular weight of 243.16 g/mol. Bretylium belongs to the phenylmethylamines, a subclass of benzene and substituted derivatives within the organic compounds. This compound is associated with six recorded sources, including electrical and electronic equipment such as electrically stimulated smoking devices, as well as household cleaning and consumer products like tobacco smoke filters, cigar cigarettes, non electric simulated smoking devices, and other smoking requisites. Additionally, it is found in healthcare, pharmaceuticals, and veterinary products, specifically within class i and iii antiarrhythmics. Recorded exposure routes for the substance include intravenous and intramuscular administration. At the molecular level, bretylium interacts with two recorded protein targets. It acts as an antagonist or inhibitor of the beta-1 adrenergic receptor (ADRB1) and the sodium/potassium-transporting ATPase subunit alpha-1 (ATP1A1).