Lanosterol (CED0003136)

Record Information
Version1.0
Creation Date2016-05-26 00:55:44 UTC
Update Date2026-05-14 17:51:19 UTC
SynCED IDCED0003136
Secondary Accession Numbers
  • CHEM029097
Identification
Common NameLanosterol
ClassSmall Molecule
Description
Lanosterol is an organic compound with the formula C30H50O and an average molecular weight of 426.72 g/mol. Lanosterol belongs to the triterpenoids, a subclass of prenol lipids within the organic compounds. Within the category of lipids and lipid-like molecules, it is further classified as a prenol lipid. The compound is associated with a single recorded protein target, lanosterol synthase (LSS). In industrial applications, lanosterol is utilized as an anti-static agent as well as a softener and conditioner. Lanosterol has been identified in nine recorded sources across various sectors. These include household cleaning and consumer products, specifically within soap detergents and perfumes used in detergents and soaps. It is also found in food, food processing, and cookware, where it is linked to food preservation and fermentation processes for beer, as well as the preparation of wine or sparkling wine. Additionally, it is recorded in electrical and electronic equipment, specifically regarding electrodes, fixed capacitors and their manufacture, electric switches, and conductors or conductive bodies characterized by the conductive materials.
Contaminant TypeNot Available
Chemical Structure
Synonyms
ValueSource
(3beta)-Lanosta-8,24-dien-3-olChEBI
(3beta,5alpha)-4,4,14-Trimethylcholesta-8,24-dien-3-olChEBI
4,4',14alpha-Trimethyl-5alpha-cholesta-8,24-dien-3beta-olChEBI
(3b)-Lanosta-8,24-dien-3-olGenerator
(3β)-Lanosta-8,24-dien-3-olGenerator
(3b,5a)-4,4,14-Trimethylcholesta-8,24-dien-3-olGenerator
(3β,5α)-4,4,14-Trimethylcholesta-8,24-dien-3-olGenerator
4,4',14a-Trimethyl-5a-cholesta-8,24-dien-3b-olGenerator
4,4',14α-Trimethyl-5α-cholesta-8,24-dien-3β-olGenerator
(3 beta)-Lanosta-8,24-dien-3-olHMDB
(3alpha)-4,4,14-Trimethyl-cholesta-8,24-dien-3-olHMDB
(3beta,5alpha)-4,4,14-Trimethyl-cholesta-8,24-dien-3-olHMDB
Botalan base 138HMDB
Lanosta-8,24-dien-3-olHMDB
Lanosta-8,24-dien-3beta-olHMDB
Lanosta-8,24-dienolHMDB
LanosterolHMDB
LansterHMDB
4,4,14 alpha-Trimethyl-5 alpha-cholesta-8,24-dien-3 beta-olMeSH, HMDB
KryptosterolMeSH, HMDB
LanosterinChEBI
3beta-Hydroxy-lansota-8,24-dien-21-oic acidHMDB
3beta-Hydroxylanosta-8,24-dieneHMDB
3β-Hydroxy-lansota-8,24-dien-21-oic acidHMDB
3β-Hydroxylanosta-8,24-dieneHMDB
4,4,14alpha-Trimethylcholesta-8,24-dien-3beta-olHMDB
4,4,14α-Trimethylcholesta-8,24-dien-3β-olHMDB
5alpha-Lanosta-8,24-dien-3beta-olHMDB
5α-Lanosta-8,24-dien-3β-olHMDB
Lanosta-8,24-dien-3β-olHMDB
Lanostadien-3beta-olHMDB
Lanostadien-3β-olHMDB
Chemical FormulaC30H50O
Average Molecular Mass426.717 g/mol
Monoisotopic Mass426.386 g/mol
CAS Registry Number79-63-0
IUPAC Name(2S,5S,7R,11R,14R,15R)-2,6,6,11,15-pentamethyl-14-[(2R)-6-methylhept-5-en-2-yl]tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-1(10)-en-5-ol
Traditional Name(2S,5S,7R,11R,14R,15R)-2,6,6,11,15-pentamethyl-14-[(2R)-6-methylhept-5-en-2-yl]tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-1(10)-en-5-ol
SMILES[H][C@@]1(CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]1(C)CC[C@H](O)C(C)(C)[C@]1([H])CC3)[C@H](C)CCC=C(C)C
InChI IdentifierInChI=1S/C30H50O/c1-20(2)10-9-11-21(3)22-14-18-30(8)24-12-13-25-27(4,5)26(31)16-17-28(25,6)23(24)15-19-29(22,30)7/h10,21-22,25-26,31H,9,11-19H2,1-8H3/t21-,22-,25+,26+,28-,29-,30+/m1/s1
InChI KeyCAHGCLMLTWQZNJ-BQNIITSRSA-N
Chemical Taxonomy
Description Belongs to the class of organic compounds known as triterpenoids. These are terpene molecules containing six isoprene units.
KingdomOrganic compounds
Super ClassLipids and lipid-like molecules
ClassPrenol lipids
Sub ClassTriterpenoids
Direct ParentTriterpenoids
Alternative Parents
Substituents
  • Triterpenoid
  • 14-alpha-methylsteroid
  • 3-beta-hydroxysteroid
  • Hydroxysteroid
  • 3-hydroxysteroid
  • Steroid
  • Cyclic alcohol
  • Secondary alcohol
  • Organic oxygen compound
  • Hydrocarbon derivative
  • Organooxygen compound
  • Alcohol
  • Aliphatic homopolycyclic compound
Molecular FrameworkAliphatic homopolycyclic compounds
External Descriptors
Biological Properties
StatusDetected and Not Quantified
OriginNot Available
Cellular LocationsNot Available
Biofluid LocationsNot Available
Tissue LocationsNot Available
ApplicationsNot Available
Biological RolesNot Available
Chemical RolesNot Available
Organoleptic EffectsNot Available
Physical Properties
StateNot Available
AppearanceNot Available
Experimental Properties
PropertyValue
Melting PointNot Available
Boiling PointNot Available
SolubilityNot Available
Predicted Properties
PropertyValueSource
Water Solubility0.00038 g/LALOGPS
logP7.72ALOGPS
logP7.71ChemAxon
logS-6.1ALOGPS
pKa (Strongest Acidic)19.55ChemAxon
pKa (Strongest Basic)-0.81ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count1ChemAxon
Hydrogen Donor Count1ChemAxon
Polar Surface Area20.23 ŲChemAxon
Rotatable Bond Count4ChemAxon
Refractivity134.54 m³·mol⁻¹ChemAxon
Polarizability55.06 ųChemAxon
Number of Rings4ChemAxon
BioavailabilityYesChemAxon
Rule of FiveNoChemAxon
Ghose FilterNoChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleNoChemAxon
Spectra
Spectra
Spectrum TypeDescriptionSplash KeyDeposition DateView
GC-MSGC-MS Spectrumsplash10-0a4l-4910000000-0fe7f84c95ab0a849fe9Not AvailableView Spectrum
GC-MSGC-MS Spectrumsplash10-03dl-2953300000-ae1832f19369485ff53cNot AvailableView Spectrum
GC-MSGC-MS Spectrumsplash10-0aou-9820200000-573525b346ad3c9eef59Not AvailableView Spectrum
GC-MSGC-MS Spectrumsplash10-0a4l-4910000000-0fe7f84c95ab0a849fe9Not AvailableView Spectrum
GC-MSGC-MS Spectrumsplash10-0a4l-2910000000-c67a1f122f33698a14f6Not AvailableView Spectrum
Predicted GC-MSPredicted GC-MS Spectrumsplash10-03dj-1009400000-e2b516142f5128a7b5f6Not AvailableView Spectrum
Predicted GC-MSPredicted GC-MS Spectrumsplash10-001i-3002900000-35e63c0bf6f033cb847cNot AvailableView Spectrum
Predicted GC-MSPredicted GC-MS SpectrumNot AvailableNot AvailableView Spectrum
Predicted GC-MSPredicted GC-MS SpectrumNot AvailableNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0a6r-0110900000-5e42e1f2d9ad534c003cNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0a4i-0230900000-10f58fa6e118cd7c5997Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0a4i-1791800000-178153ad92eececb33c4Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0a4i-2980300000-6ce95c7f8b15b35475afNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0a4j-2950100000-48f86ff7a22c596aa44dNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0592-3940000000-c35d0cb6a2e4e291e8f8Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0592-3920000000-d717fdd3322a881bef99Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0592-4910000000-4c6d07e3a8e48ae88580Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0a4j-5900000000-4c8b72037dbeae9a46d1Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-067m-8900000000-522b8688d50362297c41Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0aou-9700000000-70d433827c1a6dab0c41Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-05ox-9500000000-5b122dea636d3e3b5916Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-05r3-9500000000-0c1c5cbd994f8406f30eNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-05r3-9600000000-5cb8ae11d071fa19f206Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0ktf-0392000000-03cda521ce6e102d92e4Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-059j-2900000000-8086693fb040e5ed7501Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0a4i-4900000000-c58ff2dc28c6ba639997Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-01vk-0900000000-805937445cceda0cd70aNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0aor-0900000000-22d304b445b737121aa7Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-03ka-0900000000-62c3ad9027e479d6082aNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-067i-0900000000-da652940059c390656e4Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-0a6r-0002900000-2cfcf7ce4b5b21140eaeNot AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-0pdi-2139500000-9a25961000db9796d6daNot AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-0uxr-4259100000-9f7f26265abec4122e35Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-004i-0000900000-77a57cecc2069bee1926Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-004i-0000900000-5b0f06bf8120e780e30cNot AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-0a4l-1009400000-421e305d47b29da427d2Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-004l-9104200000-8ee941ab6792a5ab3b9aNot AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-0aou-9013000000-cb179d67807c5e9add64Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-0lfv-9533000000-93d879330971207fa9c9Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-004i-0000900000-590c9e4adfdd12b64d93Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-004i-0000900000-78dd6104ab40fb436c5eNot AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-00fr-1001900000-493f552ce99405fdada2Not AvailableView Spectrum
MSMS Spectrumsplash10-05mo-9731200000-b1bc6bb68e352e3bd687Not AvailableView Spectrum
1D NMR13C NMR Spectrum (1D, H2O, predicted)Not AvailableNot AvailableView Spectrum
1D NMR1H NMR Spectrum (1D, H2O, predicted)Not AvailableNot AvailableView Spectrum
Toxicity Profile
Toxicity Values
Toxicity ValueOrganismDose DescriptorRoute of ExposurePredicted or ExperimentalToxicity RatingReference
2140.0 Log mg/kg [1200:3800]RatLD50oralpredictedNot AvailableNot Available
Toxicity / Toxin ClassNot Available
Mechanism of ToxicityNot Available
Carcinogenicity (IARC Classification)Not Available
Minimum Risk LevelNot Available
SymptomsNot Available
TreatmentNot Available
Health Effects
Health EffectRelationshipDirectionReference
Exposure Sources
Source IDSourceSectorReference
CEDs000010Insecticides?Insecticides are synthetic chemicals designed to control or eliminate insect pests that threaten crops and other agricultural products.Agriculture & land managementNot Available
CEDs000490Personal care & cosmeticsNot Available
CEDs000511Conductors Or Conductive Bodies Characterised By The Conductive Materials?Conductors, or conductive bodies, are materials that allow the flow of electrical current, typically made from metals such as copper, aluminum, or silver.Electrical & Electronic EquipmentNot Available
CEDs000517Electric Switches?Electric switches, integral components in numerous devices, can be a source of synthetic chemical contamination due to the materials and manufacturing processes involved in their production.Electrical & Electronic EquipmentNot Available
CEDs000519Electrodes?Electrodes, used in various electrical and electronic applications, can be a source of synthetic chemical contamination due to the materials from which they are constructed and the processes involved in their manufacturing.Electrical & Electronic EquipmentNot Available
CEDs000521Fixed Capacitors And Their Manufacture?Fixed capacitors are passive electronic components used to store and release electrical energy, playing a critical role in various circuits.Electrical & Electronic EquipmentNot Available
CEDs000524Hybrid Capacitors?Hybrid capacitors are energy storage devices that combine the properties of electrolytic and supercapacitors, utilizing a combination of electrochemical principles to achieve higher energy density and power density.Electrical & Electronic EquipmentNot Available
CEDs000544Fermentation Processes For Beer?Fermentation processes for beer involve the conversion of sugars into alcohol and carbon dioxide by yeast.Food, food processing & cookwareNot Available
CEDs000545Food Preservation?Food preservation often involves the use of synthetic chemicals, such as preservatives, flavor enhancers, and color additives, to extend shelf life and enhance the sensory qualities of food products.Food, food processing & cookwareNot Available
CEDs000549Preparation Of Wine Or Sparkling Wine?The preparation of wine or sparkling wine involves various stages, including fermentation, aging, and bottling, which can introduce potential sources of synthetic chemical contamination.Food, food processing & cookwareNot Available
CEDs000556Cigar Cigarettes?Cigar cigarettes are a source of synthetic chemical contamination due to the combustion of various tobacco blends and additives.Household cleaning & consumer productsNot Available
CEDs000561Perfumes Within Detergents And Soaps?Perfumes within detergents and soaps are synthetic fragrance compounds added to enhance the sensory experience of cleaning products.Household cleaning & consumer productsNot Available
CEDs000563Soap Detergents?Soap detergents are synthetic surfactants designed to enhance the cleaning efficacy of water by reducing surface tension, allowing for better interaction with dirt and grease.Household cleaning & consumer productsNot Available
CEDs000580Manufacture Preparation Of Tobacco Products?The manufacture and preparation of tobacco products involve various processes that can result in the introduction of synthetic chemicals into the environment.Industrial manufacturing & chemical processingNot Available
CEDs000596Acaricides?Acaricides are synthetic chemicals specifically designed to target and control mite populations that can damage crops and plants.Agriculture & land managementNot Available
CEDs000597Chemosterilants?Chemosterilants are synthetic chemicals designed to induce sterility in target pest populations, thereby controlling their reproduction and mitigating damage to crops.Agriculture & land managementNot Available
CEDs000600Herbicides And Algicides?Herbicides and algicides are synthetic chemicals primarily used to control unwanted plants and algae in various environments.Agriculture & land managementNot Available
CEDs000602Molluscicides?Molluscicides are synthetic chemicals specifically designed to control and eliminate mollusks, such as snails and slugs, which can be detrimental to crops and agricultural productivity.Agriculture & land managementNot Available
CEDs000603Nematocides?Nematocides are synthetic chemicals specifically designed to control nematodes, which are microscopic roundworms that can cause significant damage to crops and plants.Agriculture & land managementNot Available
CEDs000604Pest Attractants?Pest attractants are synthetic chemicals designed to lure specific pests for monitoring or control purposes.Agriculture & land managementNot Available
CEDs000605Pest Repellants?Pest repellents, often formulated from synthetic chemicals, are widely used to protect crops from insect infestations and other pests.Agriculture & land managementNot Available
CEDs000606Plant Growth Regulators?Plant Growth Regulators (PGRs) are synthetic chemicals designed to influence the growth and development of plants.Agriculture & land managementNot Available
CEDs000607Rodenticides(1)?Rodenticides are synthetic chemicals specifically formulated to control rodent populations, serving as a crucial tool in managing pests that can damage crops and spread diseases.Agriculture & land managementNot Available
CEDs000608Rodenticides?Rodenticides are chemical substances specifically designed to control rodent populations by causing death through various mechanisms, including anticoagulation or neurotoxicity.Agriculture & land managementNot Available
CEDs000609Aftershave?Aftershave is a grooming product typically used to soothe and protect the skin following shaving.Personal care & cosmeticsNot Available
CEDs000610Aftersun Products?Aftersun products are designed to soothe and hydrate the skin after sun exposure, often containing various synthetic chemicals such as emollients, preservatives, and fragrances.Personal care & cosmeticsNot Available
CEDs000611Anti Perspirants Or Body Deoderants?Antiperspirants and body deodorants commonly contain synthetic chemicals such as aluminum compounds, parabens, and synthetic fragrances.Personal care & cosmeticsNot Available
CEDs000612Body Washing Or Cleaning Implements?Body washing or cleaning implements, such as synthetic sponges, loofahs, and washcloths, can be sources of synthetic chemical contamination due to the materials used in their production.Personal care & cosmeticsNot Available
CEDs000613Depilatories?Depilatories are products designed to remove unwanted hair through the application of synthetic chemicals that break down the protein structure of hair, facilitating its removal.Personal care & cosmeticsNot Available
CEDs000614Essential Oils Or Perfumes?Essential oils and perfumes are complex mixtures of volatile compounds derived from natural or synthetic sources, commonly used for their aromatic properties.Personal care & cosmeticsNot Available
CEDs000615Eye Makeup Products?Eye makeup products, including mascaras, eyeliners, and eyeshadows, often contain a variety of synthetic chemicals such as pigments, preservatives, and film-forming agents.Personal care & cosmeticsNot Available
CEDs000616Face Mask Cosmetics?Face mask cosmetics often contain a variety of synthetic chemicals, including preservatives, emulsifiers, and fragrances, which can contribute to chemical contamination.Personal care & cosmeticsNot Available
CEDs000617Lip Care Products?Lip care products, including lipsticks, balms, and glosses, often contain a variety of synthetic chemicals such as parabens, phthalates, and synthetic fragrances.Personal care & cosmeticsNot Available
CEDs000618Lip Makeup Products?Lip makeup products, such as lipsticks, lip glosses, and lip liners, often contain a variety of synthetic chemicals, including pigments, preservatives, and emollients.Personal care & cosmeticsNot Available
CEDs000632Apparel?Apparel production often involves the use of various synthetic chemicals, including dyes, finishing agents, and preservatives.Textiles, leather & furnishingsNot Available
CEDs000667Gaseous Fire Fighting?Gaseous fire fighting systems utilize synthetic chemicals, such as halocarbons and inert gases, to suppress fires through chemical and physical processes.Fire suppression systems & agentsNot Available
CEDs000669PFAS Fire Fighting Foam?PFAS fire fighting foam refers to a class of synthetic foams containing per- and polyfluoroalkyl substances (PFAS), which are designed to suppress flammable liquid fires.Fire suppression systems & agentsNot Available
CEDs000671Airplanes And Helicopters?Airplanes and helicopters are significant sources of synthetic chemical contamination primarily through the use of aviation fuels, lubricants, and de-icing agents.Aviation & AerospaceNot Available
CEDs000673Unmanned Aerial Vehicles?Unmanned Aerial Vehicles (UAVs), commonly known as drones, utilize various synthetic chemicals in their manufacturing, operation, and maintenance processes.Aviation & AerospaceNot Available
CEDs000678Nitrogenous Fertilisers?Nitrogenous fertilizers are synthetic chemical compounds primarily used to enhance plant growth by supplying essential nitrogen, a crucial nutrient for photosynthesis and protein synthesis.Agriculture & land managementNot Available
CEDs000679Phosphatic Fertilisers?Phosphatic fertilizers are synthetic chemical products primarily composed of phosphorus, which is essential for plant growth.Agriculture & land managementNot Available
CEDs000685Ceramics?Ceramics can be a source of synthetic chemical contamination through various additives and processing agents used in their production.Building & ConstructionNot Available
CEDs000691Non Oxide Glass?Non-oxide glass refers to a category of glasses primarily composed of materials other than silicon dioxide, such as boron oxide or phosphorous oxide.Building & ConstructionNot Available
CEDs000696Nanotechnology?Nanotechnology involves the manipulation of materials at the molecular or atomic level, typically within the range of 1 to 100 nanometers.Industrial manufacturing & chemical processingNot Available
CEDs000735Explosives?Explosives are chemical compounds or mixtures designed to undergo rapid decomposition, releasing energy in the form of gas and heat.Defense & military infrastructureNot Available
CEDs000736Fuses?Fuses are safety devices designed to protect electrical circuits by breaking the circuit when excessive current flows through.Electrical & Electronic EquipmentNot Available
CEDs000739Inks?Inks are complex mixtures composed of pigments or dyes, solvents, resins, and additives used primarily for printing and writing applications.Paper, pulp & fiber productsNot Available
CEDs000740Paper?Paper production involves the processing of wood fibers and the use of various chemicals, which can lead to synthetic chemical contamination.Paper, pulp & fiber productsNot Available
CEDs000741Pigment Pastes?Pigment pastes are concentrated dispersions of pigments used to impart color and properties to materials.Paper, pulp & fiber productsNot Available
CEDs000744Water, Wastewater, & Sewage Treatment?Water, wastewater, and sewage treatment processes are critical for managing and mitigating pollutants in water systems.Wastewater, sanitation & biosolidsNot Available
Pathways
0 pathwaysPathway Source: PathBank

No pathways found

No metabolic pathways have been associated with this synthetic chemical

Targets
StructureProteinUniProt IDOrganismRelationshipDetails
Click to view 3D structureS-adenosyl-L-methionine:delta24-sterol-C-methyltransferaseQ43445Glycine maxPredicted (SEA)
Prediction Confidence Score
0.377
Applicability Domain
0.377
Statistical Significance
1.00e-05
Supporting Reference Compounds
1
E-value
0.0778492
Prostaglandin E synthase structureClick to view 3D structureProstaglandin E synthaseO14684HumansPredicted (SEA)
Prediction Confidence Score
0.327
Applicability Domain
0.6
Statistical Significance
0.0013
Supporting Reference Compounds
69
E-value
10.2761
Prostaglandin G/H synthase 2 structureClick to view 3D structureProstaglandin G/H synthase 2P35354HumansPredicted (SEA)
Prediction Confidence Score
0.312
Applicability Domain
0.6
Statistical Significance
0.0122
Supporting Reference Compounds
201
E-value
95.2874
Bile acid receptor structureClick to view 3D structureBile acid receptorQ96RI1HumansPredicted (SEA)
Prediction Confidence Score
0.306
Applicability Domain
0.6
Statistical Significance
0.0069
Supporting Reference Compounds
94
E-value
53.4046
Prostaglandin G/H synthase 1 structureClick to view 3D structureProstaglandin G/H synthase 1P05979Ovis ariesPredicted (SEA)
Prediction Confidence Score
0.298
Applicability Domain
0.6
Statistical Significance
0.0069
Supporting Reference Compounds
106
E-value
53.7938
G-protein coupled bile acid receptor 1 structureClick to view 3D structureG-protein coupled bile acid receptor 1Q8TDU6HumansPredicted (SEA)
Prediction Confidence Score
0.296
Applicability Domain
0.6
Statistical Significance
0.0057
Supporting Reference Compounds
54
E-value
44.4519
Phospholipase A2 structureClick to view 3D structurePhospholipase A2P04054HumansPredicted (SEA)
Prediction Confidence Score
0.269
Applicability Domain
0.615
Statistical Significance
0.0041
Supporting Reference Compounds
70
E-value
31.7625
Click to view 3D structureVitamin D3 receptorA3RGC1Sus scrofaPredicted (SEA)
Prediction Confidence Score
0.262
Applicability Domain
0.262 Low confidence
Statistical Significance
5.80e-04
Supporting Reference Compounds
1
E-value
4.51525
Vitamin D-binding protein structureClick to view 3D structureVitamin D-binding proteinP02774HumansPredicted (SEA)
Prediction Confidence Score
0.262
Applicability Domain
0.262 Low confidence
Statistical Significance
5.80e-04
Supporting Reference Compounds
1
E-value
4.51525
Click to view 3D structureLanosterol synthaseQ04782YeastPredicted (SEA)
Prediction Confidence Score
0.25
Applicability Domain
0.25 Low confidence
Statistical Significance
1.30e-04
Supporting Reference Compounds
1
E-value
1.01204
Vitamin D3 receptor structureClick to view 3D structureVitamin D3 receptorP11473HumansPredicted (SEA)
Prediction Confidence Score
0.245
Applicability Domain
0.262 Low confidence
Statistical Significance
0.0196
Supporting Reference Compounds
41
E-value
152.662
Vitamin D3 receptor structureClick to view 3D structureVitamin D3 receptorP13053Rattus norvegicusPredicted (SEA)
Prediction Confidence Score
0.245
Applicability Domain
0.262 Low confidence
Statistical Significance
5.30e-04
Supporting Reference Compounds
3
E-value
4.12601
Vitamin D3 receptor A structureClick to view 3D structureVitamin D3 receptor AQ9PTN2Danio rerioPredicted (SEA)
Prediction Confidence Score
0.242
Applicability Domain
0.262 Low confidence
Statistical Significance
4.70e-04
Supporting Reference Compounds
2
E-value
3.65891
Click to view 3D structureVitamin D3 receptorO42392Gallus gallusPredicted (SEA)
Prediction Confidence Score
0.238
Applicability Domain
0.262 Low confidence
Statistical Significance
6.40e-04
Supporting Reference Compounds
2
E-value
4.98235
Click to view 3D structureVitamin D3 receptorQ28037Bos taurusPredicted (SEA)
Prediction Confidence Score
0.234
Applicability Domain
0.262 Low confidence
Statistical Significance
5.10e-04
Supporting Reference Compounds
3
E-value
3.97031
Tyrosine-protein phosphatase non-receptor type 1 structureClick to view 3D structureTyrosine-protein phosphatase non-receptor type 1P18031HumansPredicted (SEA)
Prediction Confidence Score
0.229
Applicability Domain
0.24 Low confidence
Statistical Significance
0.1184
Supporting Reference Compounds
197
E-value
922.046
FUN14 domain-containing protein 1 structureClick to view 3D structureFUN14 domain-containing protein 1Q8IVP5HumansPredicted (SEA)
Prediction Confidence Score
0.225
Applicability Domain
0.225 Low confidence
Statistical Significance
8.90e-04
Supporting Reference Compounds
1
E-value
6.92858
Nuclear receptor ROR-gamma structureClick to view 3D structureNuclear receptor ROR-gammaP51449HumansPredicted (SEA)
Prediction Confidence Score
0.222
Applicability Domain
0.225 Low confidence
Statistical Significance
0.099
Supporting Reference Compounds
102
E-value
770.863
11-beta-hydroxysteroid dehydrogenase 1 structureClick to view 3D structure11-beta-hydroxysteroid dehydrogenase 1P28845HumansPredicted (SEA)
Prediction Confidence Score
0.221
Applicability Domain
0.309
Statistical Significance
0.0404
Supporting Reference Compounds
76
E-value
314.667
Macrophage scavenger receptor types I and II structureClick to view 3D structureMacrophage scavenger receptor types I and IIP21757HumansPredicted (SEA)
Prediction Confidence Score
0.221
Applicability Domain
0.221 Low confidence
Statistical Significance
1.80e-04
Supporting Reference Compounds
1
E-value
1.40129
NPC1-like intracellular cholesterol transporter 1 structureClick to view 3D structureNPC1-like intracellular cholesterol transporter 1Q9UHC9HumansPredicted (SEA)
Prediction Confidence Score
0.22
Applicability Domain
0.225 Low confidence
Statistical Significance
0.0032
Supporting Reference Compounds
13
E-value
24.8339
Oxysterol-binding protein 1 structureClick to view 3D structureOxysterol-binding protein 1P22059HumansPredicted (SEA)
Prediction Confidence Score
0.22
Applicability Domain
0.225 Low confidence
Statistical Significance
0.0025
Supporting Reference Compounds
9
E-value
19.6959
Alpha-crystallin A chain structureClick to view 3D structureAlpha-crystallin A chainP02489HumansPredicted (SEA)
Prediction Confidence Score
0.707
Applicability Domain
0.707
Statistical Significance
1.00e-05
Supporting Reference Compounds
1
E-value
0.0778492
Click to view 3D structure7-dehydrocholesterol reductaseQ9Z2Z8Rattus norvegicusPredicted (SEA)
Prediction Confidence Score
0.612
Applicability Domain
0.612
Statistical Significance
1.00e-05
Supporting Reference Compounds
1
E-value
0.0778492
Alpha-crystallin B chain structureClick to view 3D structureAlpha-crystallin B chainP02511HumansPredicted (SEA)
Prediction Confidence Score
0.495
Applicability Domain
0.707
Statistical Significance
1.00e-05
Supporting Reference Compounds
3
E-value
0.0778492
Concentrations
Not Available
External Links
DrugBank IDDB03696
HMDB IDHMDB0001251
FooDB IDFDB013802
Phenol Explorer IDNot Available
KNApSAcK IDC00003657
BiGG ID38253
BioCyc IDLANOSTEROL
METLIN ID6108
PDB IDNot Available
Wikipedia LinkLanosterol
Chemspider ID216175
ChEBI ID16521
PubChem Compound ID246983
Kegg Compound IDC01724
YMDB IDYMDB00262
ECMDB IDM2MDB005686
References
Synthesis ReferenceNot Available
MSDSNot Available
General ReferencesNot Available