Amlodipine (CED0001914)

Amlodipine is an organic compound with the formula C20H25ClN2O5 and an average molecular weight of 408.88 g/mol. Amlodipine belongs to the hydropyridines, a subclass of pyridines and derivatives within the organic compounds. It is categorized under the superclass of organoheterocyclic compounds. The compound is found in or released from 25 recorded sources. These include healthcare, pharmaceuticals, and veterinary products, specifically calcium channel blockers, ACE inhibitors, beta blocking agents, agents acting on the renin-angiotensin system, and angiotensin ii receptor blockers (arbs). It is also associated with household cleaning and consumer products, such as bleaching agents, pipe accessories, other smoking requisites, non electric simulated smoking devices, and cigar cigarettes. Additional sources include food, food processing, and cookware, specifically food preservation and the preparation of wine or sparkling wine, as well as drinking water and water supply. It is further linked to electrical and electronic equipment, including antennas, electrodes, adjustable resistors, conductors or conductive bodies characterised by the conductive materials, and electrically stimulated smoking devices. The recorded route of exposure for this compound is oral. Amlodipine interacts with nine recorded protein targets. It acts as a blocker or inhibitor of carbonic anhydrase 1 (CA1), as well as the voltage-dependent L-type calcium channel subunit alpha-1C (CACNA1C), the voltage-dependent N-type calcium channel subunit alpha-1B (CACNA1B), and the voltage-dependent L-type calcium channel subunit beta-1 (CACNB1), among five other proteins.