pramocaine (CED0013482)

Pramocaine is an organic compound with the chemical formula C17H27NO3 and an average molecular weight of 293.41 g/mol. It belongs to the phenol ethers, a class of benzenoids within the organic compounds. This compound is found in or released from nine recorded sources across several categories. In healthcare, pharmaceuticals, and veterinary products, it is used in antipruritics and vasoprotectives. Within food, food processing, and cookware, it is utilized for food preservation. It is also present in electrical and electronic equipment, specifically in electrically stimulated smoking devices and conductors or conductive bodies characterized by the conductive materials. Additionally, it is found in household cleaning and consumer products, including soap dispensers, perfumes within detergents and soaps, cigar cigarettes, and other smoking requisites. Recorded exposure routes for pramocaine include topical, oral, auricular, rectal, and vaginal administration. At the molecular level, pramocaine interacts with ten recorded protein targets. It acts as an inhibitor of several sodium channel proteins, specifically sodium channel protein type 1 subunit alpha (SCN1A), sodium channel protein type 4 subunit alpha (SCN4A), sodium channel protein type 5 subunit alpha (SCN5A), and sodium channel protein type 7 subunit alpha (SCN7A), as well as six other proteins.