Vomitoxin (CED0002823)

Record Information
Version1.0
Creation Date2026-03-25 19:23:58 UTC
Update Date2026-05-20 19:45:18 UTC
Accession NumberCHEM055834
Identification
Common NameVomitoxin
ClassSmall Molecule
Description
Vomitoxin is an organic compound with the formula C15H20O6 and an average molecular weight of 296.32 g/mol. Vomitoxin belongs to the sesquiterpenoids, a subclass of prenol lipids within the organic compounds. Biologically, it functions as a mycotoxin (PMC12567793, PMC4811902, PMC6960266, PMC7400953), toxin (PMC8879614), xenobiotic (PMC3694158), virulence factor (PMC4811902), and metabolite (PMC7927007). The compound is found in or released from 19 recorded sources across several sectors. These include electrical and electronic equipment such as batteries, capacitors, cell phones, printed circuit boards, and wires and cables; food, food processing and cookware, including food packaging, the preparation of malt, wort, wine or sparkling wine, and fermentation processes for beer; textiles, leather and furnishings, including carpets, rugs, and synthetic textiles; healthcare, pharmaceuticals and veterinary products via medical devices; and lubricants used in energy, oil, gas, industrial manufacturing, and chemical processing. Recorded exposure routes include oral, inhalation, and touch. Vomitoxin is associated with various health effects, including nausea (PMC10675009, PMC12567793), vomiting (PMC10675009, PMC12567793, PMC6274039), diarrhea (PMC12567793, PMC6960266), and abdominal pain (PMC12567793). Additional effects include fever (PMC10675009), inflammation (PMC5748793), and ovarian cancer (PMC11640045). It is also associated with anorexia (PMC13066547, PMC6115949) and a decrease in anorexia (PMC6274039).
Contaminant Type
  • Mycotoxin
  • PFAS
Chemical Structure
SynonymsNot Available
Chemical FormulaC15H20O6
Average Molecular Mass296.319 g/mol
Monoisotopic Mass296.126 g/mol
CAS Registry Number51481-10-8;115825-61-1;50722-37-7
IUPAC NameNot Available
Traditional NameNot Available
SMILESCC1=C[C@H]2O[C@@H]3[C@H](O)C[C@@](C)([C@]33CO3)[C@@]2(CO)[C@H](O)C1=O
InChI IdentifierInChI=1S/C15H20O6/c1-7-3-9-14(5-16,11(19)10(7)18)13(2)4-8(17)12(21-9)15(13)6-20-15/h3,8-9,11-12,16-17,19H,4-6H2,1-2H3/t8-,9-,11-,12-,13-,14-,15+/m1/s1
InChI KeyLINOMUASTDIRTM-QGRHZQQGSA-N
Chemical Taxonomy
ClassificationNot classified
Biological Properties
StatusDetected and Not Quantified
OriginNot Available
Cellular LocationsNot Available
Biofluid LocationsNot Available
Tissue LocationsNot Available
ApplicationsNot Available
Biological Roles
Chemical RolesNot Available
Organoleptic EffectsNot Available
Physical Properties
StateNot Available
AppearanceNot Available
Experimental Properties
PropertyValue
Melting PointNot Available
Boiling PointNot Available
SolubilityNot Available
Predicted PropertiesNot Available
Spectra
SpectraNot Available
Toxicity Profile
Mechanism of ToxicityNot Available
Carcinogenicity (IARC Classification)Not Available
Minimum Risk LevelNot Available
SymptomsNot Available
TreatmentNot Available
Toxicity Values
Toxicity ValueUnitValue RangeOrganismDose DescriptorRoute of ExposurePredicted or ExperimentalReference
124.0Log mg/kg[70:220]RatLD50oralpredictedNot Available
Health Effects
Health EffectRelationshipDirectionReference
inflammationassociated_withNot AvailablePMC5748793
diarrheaassociated_withNot AvailablePMC12567793 , PMC6960266
feverassociated_withNot AvailablePMC10675009
abdominal painassociated_withNot AvailablePMC12567793
nauseaassociated_withNot AvailablePMC10675009 , PMC12567793
vomitingassociated_withNot AvailablePMC10675009 , PMC12567793 , PMC6274039
ovarian cancerassociated_withNot AvailablePMC11640045
anorexiaassociated_withNot AvailablePMC13066547 , PMC6115949
anorexiaassociated_withdecreasePMC6274039
Exposure Sources
Source IDSourceSectorReference
7PesticidesAgriculture & land managementNot Available
120Wires and cablesElectrical & Electronic EquipmentNot Available
121Printed circuit boardsElectrical & Electronic EquipmentNot Available
125BatteriesElectrical & Electronic EquipmentNot Available
130SemiconductorsElectrical & Electronic EquipmentNot Available
138LubricantsEnergy, oil & gasNot Available
147Food packagingFood, food processing & cookwareNot Available
174LubricantsIndustrial manufacturing & chemical processingNot Available
234Medical devicesHealthcare, pharmaceuticals & veterinary productsNot Available
451Carpets and RugsTextiles, leather & furnishingsNot Available
454Synthetic textilesTextiles, leather & furnishingsNot Available
490Personal care & cosmeticsNot Available
492Cell phonesElectrical & Electronic EquipmentNot Available
493CapacitorsElectrical & Electronic EquipmentNot Available
527MagnetsElectrical & Electronic EquipmentNot Available
544Fermentation Processes For BeerFood, food processing & cookwareNot Available
547Preparation Of MaltFood, food processing & cookwareNot Available
549Preparation Of Wine Or Sparkling WineFood, food processing & cookwareNot Available
550Preparation Of WortFood, food processing & cookwareNot Available
555Bleaching AgentsHousehold cleaning & consumer productsNot Available
604Pest AttractantsAgriculture & land managementNot Available
607Rodenticides(1)Agriculture & land managementNot Available
608RodenticidesAgriculture & land managementNot Available
Pathways
0 pathways

No pathways found

No metabolic pathways have been associated with this synthetic chemical

Targets
StructureProteinUniProt IDOrganismRelationshipDetails
Tubulin--tyrosine ligase structureClick to view 3D structureTubulin--tyrosine ligaseQ8NG68HumansPredicted (SEA)0.311397
Asialoglycoprotein receptor 1 structureClick to view 3D structureAsialoglycoprotein receptor 1P07306HumansPredicted (SEA)2.49118
Click to view 3D structureProstaglandin reductase 1P97584Rattus norvegicusPredicted (SEA)0.544945
Click to view 3D structureEcdysone receptorP34021Drosophila melanogasterPredicted (SEA)11.1324
Click to view 3D structureGlycine receptor subunit alpha-2P22771Rattus norvegicusPredicted (SEA)0.700643
Thymidine kinase, cytosolic structureClick to view 3D structureThymidine kinase, cytosolicP04183HumansPredicted (SEA)34.098
Glucocorticoid receptor structureClick to view 3D structureGlucocorticoid receptorP04150HumansPredicted (SEA)3489.82
Mineralocorticoid receptor structureClick to view 3D structureMineralocorticoid receptorP08235HumansPredicted (SEA)2113.92
Click to view 3D structureNADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11Q8HXG6Bos taurusPredicted (SEA)41.5715
Click to view 3D structurePhospholipase A2 alphaP00623Crotalus adamanteusPredicted (SEA)3.50322
Click to view 3D structureSucrase-isomaltase, intestinalP23739Rattus norvegicusPredicted (SEA)29.3492
Corticosteroid-binding globulin structureClick to view 3D structureCorticosteroid-binding globulinP08185HumansPredicted (SEA)68.5073
Macrophage scavenger receptor types I and II structureClick to view 3D structureMacrophage scavenger receptor types I and IIP21757HumansPredicted (SEA)7.39568
Click to view 3D structureSerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoformQ76MZ3Mus musculusPredicted (SEA)3.03612
Click to view 3D structureFumarate reductaseF1KRD8Ascaris suumPredicted (SEA)0.544945
Click to view 3D structureThymidine kinaseP06479Human herpesvirus 1 (strain SC16) (HHV-1) (Human herpes simplex virus1)Predicted (SEA)82.598
Click to view 3D structureGamma-aminobutyric acid receptor subunit alpha-4P28471Rattus norvegicusPredicted (SEA)16.4262
Maltase-glucoamylase structureClick to view 3D structureMaltase-glucoamylaseO43451HumansPredicted (SEA)134.056
Tyrosine-protein phosphatase non-receptor type 1 structureClick to view 3D structureTyrosine-protein phosphatase non-receptor type 1P18031HumansPredicted (SEA)4334.33
Protein kinase C gamma type structureClick to view 3D structureProtein kinase C gamma typeP05129HumansPredicted (SEA)7205.26
Click to view 3D structureProgesterone receptorQ690N0Bos taurusPredicted (SEA)282.904
Sex hormone-binding globulin structureClick to view 3D structureSex hormone-binding globulinP04278HumansPredicted (SEA)144.177
Click to view 3D structureGlucocorticoid receptorP06536Rattus norvegicusPredicted (SEA)508.044
Thymidylate synthase structureClick to view 3D structureThymidylate synthaseP00469Lactobacillus caseiPredicted (SEA)942.832
Click to view 3D structureLong-chain fatty acid transport protein 4Q6P1M0HumansPredicted (SEA)138.338
Concentrations
Not Available
External Links
IdentifiersNot Available
References
Synthesis ReferenceNot Available
MSDSNot Available
General ReferencesNot Available