T-2 toxin (CED0003175)

Record Information
Version1.0
Creation Date2026-03-25 19:34:20 UTC
Update Date2026-05-20 19:45:35 UTC
SynCED IDCED0003175
Secondary Accession Numbers
  • CHEM055844
Identification
Common NameT-2 toxin
ClassSmall Molecule
Description
T-2 toxin is a compound with the formula C24H34O9 and an average molecular weight of 466.53 g/mol. T-2 toxin belongs to the sesquiterpenoids, a subclass of prenol lipids within the organic compounds. Biologically, it functions as a mycotoxin (PMC7076805). The compound is found in or released from 15 recorded sources. These include lubricants used in energy, oil & gas and industrial manufacturing & chemical processing; medical devices in the healthcare, pharmaceuticals & veterinary products sector; synthetic textiles, carpets and rugs in textiles, leather & furnishings; and food packaging, food contact materials, and the preparation of malt in food, food processing & cookware. It is also associated with electrical & electronic equipment, including cell phones, capacitors, wires and cables, batteries, and printed circuit boards, among one more sector. Recorded routes of exposure include oral, inhalation, and touch. T-2 toxin is associated with several health effects. It is linked to the occurrence of nausea, fever, diarrhea, and necrosis (PMC11019184), as well as vomiting (PMC10620813).
Contaminant Type
  • Mycotoxin
  • PFAS
Chemical Structure
SynonymsNot Available
Chemical FormulaC24H34O9
Average Molecular Mass466.527 g/mol
Monoisotopic Mass466.220 g/mol
CAS Registry Number21259-20-1;11051-21-1;22916-10-5;22916-18-3;25152-34-5;26400-47-5;27640-92-2;36653-66-4;60119-99-5;9061-58-9
IUPAC NameNot Available
Traditional NameNot Available
SMILESCC(C)CC(=O)O[C@H]1C[C@@]2(COC(C)=O)[C@H](O[C@@H]3[C@H](O)[C@@H](OC(C)=O)[C@@]2(C)[C@]32CO2)C=C1C
InChI IdentifierInChI=1S/C24H34O9/c1-12(2)7-18(27)32-16-9-23(10-29-14(4)25)17(8-13(16)3)33-21-19(28)20(31-15(5)26)22(23,6)24(21)11-30-24/h8,12,16-17,19-21,28H,7,9-11H2,1-6H3/t16-,17+,19+,20+,21+,22+,23+,24-/m0/s1
InChI KeyBXFOFFBJRFZBQZ-QYWOHJEZSA-N
Chemical Taxonomy
ClassificationNot classified
Biological Properties
StatusDetected and Not Quantified
OriginNot Available
Cellular LocationsNot Available
Biofluid LocationsNot Available
Tissue LocationsNot Available
ApplicationsNot Available
Biological Roles
  • mycotoxin (PMC7076805 )?A chemical substance naturally produced by fungi and poisonous to other organisms
Chemical RolesNot Available
Organoleptic EffectsNot Available
Physical Properties
StateNot Available
AppearanceNot Available
Experimental Properties
PropertyValue
Melting PointNot Available
Boiling PointNot Available
SolubilityNot Available
Predicted PropertiesNot Available
Spectra
SpectraNot Available
Toxicity Profile
Toxicity Values
Toxicity ValueOrganismDose DescriptorRoute of ExposurePredicted or ExperimentalToxicity RatingReference
32.0 Log mg/kg [20:57]RatLD50oralpredictedNot AvailableNot Available
10.0 ppm MouseLOELoralexperimentalNot AvailableECOTOX - EPA ORD
10.0 ppm MouseLOELoralexperimentalNot AvailableECOTOX - EPA ORD
10.0 ppm MouseNOELoralexperimentalNot AvailableECOTOX - EPA ORD
10.0 ppm MouseNOELoralexperimentalNot AvailableECOTOX - EPA ORD
10.0 ppm MouseLOELoralexperimentalNot AvailableECOTOX - EPA ORD
10.0 ppm MouseLOELoralexperimentalNot AvailableECOTOX - EPA ORD
Toxicity / Toxin ClassNot Available
Mechanism of ToxicityNot Available
Carcinogenicity (IARC Classification)Not Available
Minimum Risk LevelNot Available
SymptomsNot Available
TreatmentNot Available
Health Effects
Health EffectRelationshipDirectionReference
diarrhea?A disorder characterized by an increase in frequency and/or loose or watery bowel movements. (NCI CTCAE)associated_withNot AvailablePMC11019184
fever?A disorder characterized by an abnormally high body temperature.associated_withNot AvailablePMC11019184
necrosis?A disorder characterized as a form of cell injury which results in the premature death of cells in living tissue by autolysis.associated_withNot AvailablePMC11019184
nausea?A disorder characterized by a queasy sensation and/or the urge to vomit. (NCI CTCAE)associated_withNot AvailablePMC11019184
vomiting?A disorder characterized by the reflexive act of ejecting the contents of the stomach through the mouth. (NCI CTCAE)associated_withNot AvailablePMC10620813
Exposure Sources
Source IDSourceSectorReference
CEDs000007Pesticides?Pesticides are synthetic chemicals designed to prevent, destroy, or control pests that threaten crops and agricultural productivity.Agriculture & land managementNot Available
CEDs000120Wires and cables?Wires and cables are integral components in the transmission of electrical power and signals.Electrical & Electronic EquipmentNot Available
CEDs000121Printed circuit boards?Printed circuit boards (PCBs) are essential components in the manufacturing of electronic devices, serving as the backbone for electrical connections and circuit pathways.Electrical & Electronic EquipmentNot Available
CEDs000125Batteries?Batteries are devices that store and release electrical energy through electrochemical reactions.Electrical & Electronic EquipmentNot Available
CEDs000130Semiconductors?Semiconductors are materials that possess electrical conductivity between that of conductors and insulators, making them essential for various electronic applications, including transistors, diodes, and integrated circuits.Electrical & Electronic EquipmentNot Available
CEDs000138Lubricants?Lubricants are synthetic or petroleum-derived substances used to reduce friction between surfaces in machinery and equipment, enhancing operational efficiency and longevity.Energy, oil & gasNot Available
CEDs000147Food packaging?Food packaging often utilizes synthetic chemicals, such as plastics and coatings, to enhance durability, moisture resistance, and shelf life.Food, food processing & cookwareNot Available
CEDs000174Lubricants?Lubricants are synthetic or petroleum-based substances used to reduce friction and wear between moving parts in machinery and equipment.Industrial manufacturing & chemical processingNot Available
CEDs000234Medical devices?Medical devices often incorporate synthetic chemicals in their manufacturing processes, which can contribute to contamination in healthcare settings.Healthcare, pharmaceuticals & veterinary productsNot Available
CEDs000451Carpets and Rugs?Carpets and rugs are commonly manufactured using synthetic fibers such as nylon, polyester, and polypropylene, which can be derived from petrochemical sources.Textiles, leather & furnishingsNot Available
CEDs000454Synthetic textiles?Synthetic textiles are materials derived from man-made fibers, such as polyester, nylon, and acrylic, which are produced through chemical processes involving petrochemicals.Textiles, leather & furnishingsNot Available
CEDs000490Personal care & cosmeticsNot Available
CEDs000492Cell phones?Cell phones contain a variety of synthetic chemicals and materials, including plastics, metals, and glass, which can contribute to environmental contamination.Electrical & Electronic EquipmentNot Available
CEDs000493Capacitors?Capacitors are electronic components that store and release electrical energy, often using dielectric materials that can include synthetic chemicals.Electrical & Electronic EquipmentNot Available
CEDs000494Food contact materials?Food contact materials refer to substances and products that are intended to come into contact with food during processing, packaging, or preparation.Food, food processing & cookwareNot Available
CEDs000521Fixed Capacitors And Their Manufacture?Fixed capacitors are passive electronic components used to store and release electrical energy, playing a critical role in various circuits.Electrical & Electronic EquipmentNot Available
CEDs000545Food Preservation?Food preservation often involves the use of synthetic chemicals, such as preservatives, flavor enhancers, and color additives, to extend shelf life and enhance the sensory qualities of food products.Food, food processing & cookwareNot Available
CEDs000547Preparation Of Malt?Malt preparation involves the germination and drying of cereal grains, primarily barley, to produce malt for brewing and food products.Food, food processing & cookwareNot Available
CEDs000555Bleaching Agents?Bleaching agents are chemical substances used to whiten or lighten materials, often employed in various cleaning products for their stain removal and disinfecting properties.Household cleaning & consumer productsNot Available
CEDs000561Perfumes Within Detergents And Soaps?Perfumes within detergents and soaps are synthetic fragrance compounds added to enhance the sensory experience of cleaning products.Household cleaning & consumer productsNot Available
CEDs000580Manufacture Preparation Of Tobacco Products?The manufacture and preparation of tobacco products involve various processes that can result in the introduction of synthetic chemicals into the environment.Industrial manufacturing & chemical processingNot Available
CEDs000606Plant Growth Regulators?Plant Growth Regulators (PGRs) are synthetic chemicals designed to influence the growth and development of plants.Agriculture & land managementNot Available
CEDs000632Apparel?Apparel production often involves the use of various synthetic chemicals, including dyes, finishing agents, and preservatives.Textiles, leather & furnishingsNot Available
CEDs000696Nanotechnology?Nanotechnology involves the manipulation of materials at the molecular or atomic level, typically within the range of 1 to 100 nanometers.Industrial manufacturing & chemical processingNot Available
CEDs000744Water, Wastewater, & Sewage Treatment?Water, wastewater, and sewage treatment processes are critical for managing and mitigating pollutants in water systems.Wastewater, sanitation & biosolidsNot Available
Pathways
0 pathwaysPathway Source: PathBank

No pathways found

No metabolic pathways have been associated with this synthetic chemical

Targets
StructureProteinUniProt IDOrganismRelationshipDetails
Neurogenic locus notch homolog protein 1 structureClick to view 3D structureNeurogenic locus notch homolog protein 1Q01705Mus musculusPredicted (SEA)
Prediction Confidence Score
0.195
Applicability Domain
0.195 Low confidence
Statistical Significance
0.0016
Supporting Reference Compounds
1
E-value
12.2223
Click to view 3D structureATP-dependent clpX-like chaperone, mitochondrialO76031HumansPredicted (SEA)
Prediction Confidence Score
0.191
Applicability Domain
0.191 Low confidence
Statistical Significance
0.0029
Supporting Reference Compounds
1
E-value
22.8098
Delta-type opioid receptor structureClick to view 3D structureDelta-type opioid receptorP41143HumansPredicted (SEA)
Prediction Confidence Score
0.191
Applicability Domain
0.2 Low confidence
Statistical Significance
0.7272
Supporting Reference Compounds
427
E-value
5661.27
Muscarinic acetylcholine receptor M3 structureClick to view 3D structureMuscarinic acetylcholine receptor M3P08483Rattus norvegicusPredicted (SEA)
Prediction Confidence Score
0.189
Applicability Domain
0.202 Low confidence
Statistical Significance
0.2421
Supporting Reference Compounds
55
E-value
1885.04
Kappa-type opioid receptor structureClick to view 3D structureKappa-type opioid receptorP41145HumansPredicted (SEA)
Prediction Confidence Score
0.188
Applicability Domain
0.2 Low confidence
Statistical Significance
0.8539
Supporting Reference Compounds
532
E-value
6647.39
Click to view 3D structureMuscarinic receptor 4Q8VH25Cavia porcellusPredicted (SEA)
Prediction Confidence Score
0.186
Applicability Domain
0.186 Low confidence
Statistical Significance
0.0245
Supporting Reference Compounds
1
E-value
191.042
DNA ligase A structureClick to view 3D structureDNA ligase AP9WNV1Mycobacterium tuberculosisPredicted (SEA)
Prediction Confidence Score
0.185
Applicability Domain
0.185 Low confidence
Statistical Significance
0.0291
Supporting Reference Compounds
1
E-value
226.853
Protein kinase C alpha type structureClick to view 3D structureProtein kinase C alpha typeP17252HumansPredicted (SEA)
Prediction Confidence Score
0.184
Applicability Domain
0.191 Low confidence
Statistical Significance
0.7485
Supporting Reference Compounds
258
E-value
5826.7
Protein kinase C delta type structureClick to view 3D structureProtein kinase C delta typeP28867Mus musculusPredicted (SEA)
Prediction Confidence Score
0.184
Applicability Domain
0.191 Low confidence
Statistical Significance
0.0099
Supporting Reference Compounds
12
E-value
77.46
Mu-type opioid receptor structureClick to view 3D structureMu-type opioid receptorP35372HumansPredicted (SEA)
Prediction Confidence Score
0.184
Applicability Domain
0.2 Low confidence
Statistical Significance
0.8636
Supporting Reference Compounds
527
E-value
6722.83
Solute carrier organic anion transporter family member 1B1 structureClick to view 3D structureSolute carrier organic anion transporter family member 1B1Q9Y6L6HumansPredicted (SEA)
Prediction Confidence Score
0.183
Applicability Domain
0.198 Low confidence
Statistical Significance
0.3724
Supporting Reference Compounds
82
E-value
2898.79
Click to view 3D structureMuscarinic acetylcholine receptor M3Q8VH26Cavia porcellusPredicted (SEA)
Prediction Confidence Score
0.181
Applicability Domain
0.198 Low confidence
Statistical Significance
0.2243
Supporting Reference Compounds
52
E-value
1746.24
Growth hormone-releasing hormone receptor structureClick to view 3D structureGrowth hormone-releasing hormone receptorQ02643HumansPredicted (SEA)
Prediction Confidence Score
0.181
Applicability Domain
0.181 Low confidence
Statistical Significance
0.0033
Supporting Reference Compounds
1
E-value
26.0016
Muscarinic acetylcholine receptor M3 structureClick to view 3D structureMuscarinic acetylcholine receptor M3P20309HumansPredicted (SEA)
Prediction Confidence Score
0.181
Applicability Domain
0.202 Low confidence
Statistical Significance
0.8343
Supporting Reference Compounds
310
E-value
6494.88
Muscarinic acetylcholine receptor M1 structureClick to view 3D structureMuscarinic acetylcholine receptor M1P11229HumansPredicted (SEA)
Prediction Confidence Score
0.181
Applicability Domain
0.202 Low confidence
Statistical Significance
0.8789
Supporting Reference Compounds
385
E-value
6842.09
Muscarinic acetylcholine receptor M2 structureClick to view 3D structureMuscarinic acetylcholine receptor M2P08172HumansPredicted (SEA)
Prediction Confidence Score
0.181
Applicability Domain
0.202 Low confidence
Statistical Significance
0.8777
Supporting Reference Compounds
373
E-value
6833.22
Muscarinic acetylcholine receptor M4 structureClick to view 3D structureMuscarinic acetylcholine receptor M4P08173HumansPredicted (SEA)
Prediction Confidence Score
0.181
Applicability Domain
0.202 Low confidence
Statistical Significance
0.8156
Supporting Reference Compounds
297
E-value
6349.38
Click to view 3D structureMuscarinic acetylcholine receptor M2P10980Rattus norvegicusPredicted (SEA)
Prediction Confidence Score
0.18
Applicability Domain
0.202 Low confidence
Statistical Significance
0.4145
Supporting Reference Compounds
98
E-value
3226.54
Muscarinic acetylcholine receptor M5 structureClick to view 3D structureMuscarinic acetylcholine receptor M5P08912HumansPredicted (SEA)
Prediction Confidence Score
0.18
Applicability Domain
0.202 Low confidence
Statistical Significance
0.8097
Supporting Reference Compounds
266
E-value
6303.22
Solute carrier organic anion transporter family member 1B3 structureClick to view 3D structureSolute carrier organic anion transporter family member 1B3Q9NPD5HumansPredicted (SEA)
Prediction Confidence Score
0.18
Applicability Domain
0.198 Low confidence
Statistical Significance
0.2351
Supporting Reference Compounds
51
E-value
1830.39
Protein kinase C epsilon type structureClick to view 3D structureProtein kinase C epsilon typeQ02156HumansPredicted (SEA)
Prediction Confidence Score
0.179
Applicability Domain
0.191 Low confidence
Statistical Significance
0.7782
Supporting Reference Compounds
189
E-value
6058.54
Cytochrome P450 3A4 structureClick to view 3D structureCytochrome P450 3A4P08684HumansPredicted (SEA)
Prediction Confidence Score
0.178
Applicability Domain
0.19 Low confidence
Statistical Significance
0.9858
Supporting Reference Compounds
1538
E-value
7674.61
Click to view 3D structureMuscarinic acetylcholine receptor M1P08482Rattus norvegicusPredicted (SEA)
Prediction Confidence Score
0.177
Applicability Domain
0.202 Low confidence
Statistical Significance
0.5728
Supporting Reference Compounds
109
E-value
4459.36
Click to view 3D structureSarcoplasmic/endoplasmic reticulum calcium ATPase 1O14983HumansPredicted (SEA)
Prediction Confidence Score
0.177
Applicability Domain
0.192 Low confidence
Statistical Significance
1.00e-03
Supporting Reference Compounds
3
E-value
7.78492
Epidermal growth factor receptor structureClick to view 3D structureEpidermal growth factor receptorP00533HumansPredicted (SEA)
Prediction Confidence Score
0.177
Applicability Domain
0.197 Low confidence
Statistical Significance
0.9704
Supporting Reference Compounds
1301
E-value
7554.64
Concentrations
Not Available
External Links
IdentifiersNot Available
References
Synthesis ReferenceNot Available
MSDSNot Available
General ReferencesNot Available