Dodecaethlene glycol (PEG-12) (CED0011458)

Record Information

Version

1.0

Creation Date

2026-03-26 19:12:02 UTC

Update Date

2026-08-22 04:25:19 UTC

Accession Number

CHEM056152

Identification

Common Name

Dodecaethlene glycol (PEG-12)

Class

Small Molecule

Description

Dodecaethlene glycol (PEG-12) belongs to the ethers, a subclass of organooxygen compounds within the organic compounds. With a formula of C24H50O13 and an average molecular weight of 546.65 g/mol, Dodecaethlene glycol (PEG-12) is a heavy molecule. This compound is found in or released from five recorded sources. These include household cleaning and consumer products such as soap dispensers and tobacco product cases, as well as indoor air, dust, and atmospheric transport. Additionally, it is associated with food contact materials used in food, food processing, and cookware, and is found in emergency protective devices within electrical and electronic equipment. Recorded exposure routes for Dodecaethlene glycol (PEG-12) include inhalation, oral, and touch.

Contaminant Type

Not Available

Chemical Structure

MOL SDF PDB SMILES InChI

Synonyms

Not Available

Chemical Formula

C₂₄H₅₀O₁₃

Average Molecular Mass

546.651 g/mol

Monoisotopic Mass

546.325 g/mol

CAS Registry Number

06-09-90

IUPAC Name

3,6,9,12,15,18,21,24,27,30,33-undecaoxapentatriacontane-1,35-diol

Traditional Name

dodecaethylene glycol

SMILES

OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO

InChI Identifier

InChI=1S/C24H50O13/c25-1-3-27-5-7-29-9-11-31-13-15-33-17-19-35-21-23-37-24-22-36-20-18-34-16-14-32-12-10-30-8-6-28-4-2-26/h25-26H,1-24H2

InChI Key

WRZXKWFJEFFURH-UHFFFAOYSA-N

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as polyethylene glycols. These are oligomers or polymers of ethylene oxide, with the general formula (C2H4O)n (with n>=3).

Kingdom

Organic compounds

Super Class

Organic oxygen compounds

Class

Organooxygen compounds

Sub Class

Ethers

Direct Parent

Polyethylene glycols

Alternative Parents

Substituents

Polyethylene glycol
Hydrocarbon derivative
Primary alcohol
Alcohol
Aliphatic acyclic compound

Molecular Framework

Aliphatic acyclic compounds

External Descriptors

poly(ethylene glycol) (CHEBI:39524 )

Biological Properties

Status

Detected and Not Quantified

Origin

Not Available

Cellular Locations

Not Available

Biofluid Locations

Not Available

Tissue Locations

Not Available

Applications

Not Available

Biological Roles

Not Available

Chemical Roles

Not Available

Organoleptic Effects

Not Available

Physical Properties

State

Not Available

Appearance

Not Available

Experimental Properties

Property	Value
Melting Point	Not Available
Boiling Point	Not Available
Solubility	Not Available

Predicted Properties

Property	Value	Source
Water Solubility	0.11 g/L	ALOGPS
logP	-0.85	ALOGPS
logP	-1.7	ChemAxon
logS	-3.7	ALOGPS
pKa (Strongest Acidic)	14.82	ChemAxon
pKa (Strongest Basic)	-2.7	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	13	ChemAxon
Hydrogen Donor Count	2	ChemAxon
Polar Surface Area	141.99 Å²	ChemAxon
Rotatable Bond Count	34	ChemAxon
Refractivity	136.03 m³·mol⁻¹	ChemAxon
Polarizability	65.2 Å³	ChemAxon
Number of Rings	0	ChemAxon
Bioavailability	No	ChemAxon
Rule of Five	No	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

Spectra

Not Available

Toxicity Profile

Mechanism of Toxicity

Not Available

Carcinogenicity (IARC Classification)

Not Available

Minimum Risk Level

Not Available

Symptoms

Not Available

Treatment

Not Available

Toxicity Values

Not Available

Health Effects

Health Effect	Relationship	Direction	Reference

Exposure Sources

Source ID	Source	Sector	Reference
19	Indoor air	Air, dust & atmospheric transport	Not Available
233	Brushes	Personal care & cosmetics	Not Available
490		Personal care & cosmetics	Not Available
494	Food contact materials	Food, food processing & cookware	Not Available
520	Emergency Protective Devices	Electrical & Electronic Equipment	Not Available
564	Soap Dispensers	Household cleaning & consumer products	Not Available
567	Tobacco Product Cases	Household cleaning & consumer products	Not Available
612	Body Washing Or Cleaning Implements	Personal care & cosmetics	Not Available
619	Manicure Pedicure	Personal care & cosmetics	Not Available

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this synthetic chemical

Targets

Structure	Protein	UniProt ID	Organism	Relationship	Details
Click to view 3D structure	Uridine phosphorylase 1	P52624	Mus musculus	Predicted (SEA)	61.0338
Click to view 3D structure	Non-lysosomal glucosylceramidase	Q9HCG7	Humans	Predicted (SEA)	149.704
Click to view 3D structure	Ceramide glucosyltransferase	O88693	Mus musculus	Predicted (SEA)	164.184
Click to view 3D structure	Muscarinic acetylcholine receptor M1	P11229	Humans	Predicted (SEA)	7460.29
Click to view 3D structure	Uridine phosphorylase 1	Q16831	Humans	Predicted (SEA)	89.6823
Click to view 3D structure	Muscarinic acetylcholine receptor M2	P08172	Humans	Predicted (SEA)	7491.66
Click to view 3D structure	Muscarinic acetylcholine receptor M5	P08912	Humans	Predicted (SEA)	7409.69
Click to view 3D structure	Leucine--tRNA ligase	P9WFV1	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	Predicted (SEA)	59.7882
Click to view 3D structure	Muscarinic acetylcholine receptor M3	P20309	Humans	Predicted (SEA)	7538.06
Click to view 3D structure	Sucrase-isomaltase	B5THE3	Mus musculus	Predicted (SEA)	84.0772
Click to view 3D structure	Lysosomal acid glucosylceramidase	P04062	Humans	Predicted (SEA)	2529.09
Click to view 3D structure	Muscarinic acetylcholine receptor M4	P08173	Humans	Predicted (SEA)	7577.45
Click to view 3D structure	Sodium- and chloride-dependent creatine transporter 1	P28570	Rattus norvegicus	Predicted (SEA)	51.9254
Click to view 3D structure	5-hydroxytryptamine receptor 2A	P28223	Humans	Predicted (SEA)	7741.87
Click to view 3D structure	Sodium-dependent dopamine transporter	Q01959	Humans	Predicted (SEA)	7714.94
Click to view 3D structure	5-hydroxytryptamine receptor 7	P34969	Humans	Predicted (SEA)	7696.72
Click to view 3D structure	Maltase-glucoamylase	O43451	Humans	Predicted (SEA)	1299.93
Click to view 3D structure	5-hydroxytryptamine receptor 2C	P28335	Humans	Predicted (SEA)	7740.24
Click to view 3D structure	Phenylalanine--tRNA ligase alpha subunit	Q97S36	Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)	Predicted (SEA)	511.469
Click to view 3D structure	Phenylalanine--tRNA ligase alpha subunit	P43819	Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)	Predicted (SEA)	511.469
Click to view 3D structure	D(3) dopamine receptor	P35462	Humans	Predicted (SEA)	7731.44
Click to view 3D structure	Alpha-1A adrenergic receptor	P35348	Humans	Predicted (SEA)	7688.31
Click to view 3D structure	Lysosomal alpha-glucosidase	Q6P7A9	Rattus norvegicus	Predicted (SEA)	90.6943
Click to view 3D structure	Voltage-gated inwardly rectifying potassium channel KCNH2	Q12809	Humans	Predicted (SEA)	7764.14
Click to view 3D structure	Spermine synthase	Q3SZA5	Bos taurus	Predicted (SEA)	5.60514