Sisomicin (CED0007722)

Record Information

Version

1.0

Creation Date

2026-03-31 20:20:29 UTC

Update Date

2026-05-14 19:23:35 UTC

Accession Number

CHEM057750

Identification

Common Name

Sisomicin

Class

Small Molecule

Description

Sisomicin is an organic compound with the chemical formula C19H37N5O7 and an average molecular weight of 447.53 g/mol. Sisomicin belongs to the carbohydrates and carbohydrate conjugates, a subclass of organooxygen compounds within the organic compounds. This substance is recorded as being found in or released from 16 different sources. Within the healthcare, pharmaceuticals, and veterinary products category, it is used as an antibiotic. Other recorded sources include building and construction materials, specifically roofs, tents, or canopies. Additionally, it is associated with electrical and electronic equipment, including amplifiers, antennas, auxiliary devices, colour television systems, and communication cables or conductors, among eight other devices. Recorded routes of exposure for this compound include oral and inhalation.

Contaminant Type

Not Available

Chemical Structure

MOL SDF PDB SMILES InChI

Synonyms

Not Available

Chemical Formula

C₁₉H₃₇N₅O₇

Average Molecular Mass

447.533 g/mol

Monoisotopic Mass

447.269 g/mol

CAS Registry Number

32385-11-8

IUPAC Name

Not Available

Traditional Name

Not Available

SMILES

CN[C@@H]1[C@@H](O)[C@@H](O[C@H]2[C@H](N)C[C@H](N)[C@@H](OC3OC(CN)=CCC3N)[C@@H]2O)OC[C@]1(C)O

InChI Identifier

InChI=1S/C19H37N5O7/c1-19(27)7-28-18(13(26)16(19)24-2)31-15-11(23)5-10(22)14(12(15)25)30-17-9(21)4-3-8(6-20)29-17/h3,9-18,24-27H,4-7,20-23H2,1-2H3/t9-,10+,11-,12+,13-,14-,15+,16-,17-,18-,19+/m1/s1

InChI Key

URWAJWIAIPFPJE-YFMIWBNJSA-N

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as aminocyclitol glycosides. These are organic compounds containing an amicocyclitol moiety glycosidically linked to a carbohydrate moiety. There are two major classes of aminoglycosides containing a 2-streptamine core. They are called 4,5- and 4,6-disubstituted 2-deoxystreptamines.

Kingdom

Organic compounds

Super Class

Organic oxygen compounds

Class

Organooxygen compounds

Sub Class

Carbohydrates and carbohydrate conjugates

Direct Parent

Aminocyclitol glycosides

Alternative Parents

Substituents

Amino cyclitol glycoside
O-glycosyl compound
Glycosyl compound
Aminocyclitol or derivatives
Cyclohexylamine
Cyclohexanol
Oxane
Monosaccharide
Cyclitol or derivatives
Tertiary alcohol
Cyclic alcohol
Secondary alcohol
1,2-aminoalcohol
Oxacycle
Organoheterocyclic compound
Secondary amine
Secondary aliphatic amine
Acetal
Organic nitrogen compound
Organopnictogen compound
Hydrocarbon derivative
Primary amine
Organonitrogen compound
Primary aliphatic amine
Amine
Alcohol
Aliphatic heteromonocyclic compound

Molecular Framework

Aliphatic heteromonocyclic compounds

External Descriptors

Not Available

Biological Properties

Status

Detected and Not Quantified

Origin

Not Available

Cellular Locations

Not Available

Biofluid Locations

Not Available

Tissue Locations

Not Available

Applications

Not Available

Biological Roles

Not Available

Chemical Roles

Not Available

Organoleptic Effects

Not Available

Physical Properties

State

Not Available

Appearance

Not Available

Experimental Properties

Property	Value
Melting Point	Not Available
Boiling Point	Not Available
Solubility	Not Available

Predicted Properties

Not Available

Spectra

Spectrum Type	Description	Splash Key	Deposition Date	View
LC-MS/MS	LC-MS/MS Spectrum	splash10-0002-0000900000-c257d090490406f3043c	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-0002-0010900000-e957e2ece6cb00541b9b	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-0f79-2960000000-e4019234db0edb127967	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-0zmi-9500000000-581186dcec1f1ab9320d	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-0ab9-9100000000-ccd5691ace392b03e90b	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-0002-0000900000-060193de09eeb53e3e1a	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-0230-0274900000-3f1be89196073a2aef6c	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-0ir0-0970000000-e8083a0ffe7791382e2b	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-03di-0920000000-eea6c730484f1d2fcc1d	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-0nmi-3900000000-df6cc4b9d9d4d7f88835	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-00di-0591000000-0785a7498e5373b2d8a0	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-03fr-1910000000-e0b1b4029b0e6a0848b9	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-03e9-6900000000-fbac675bcbadc5d332ff	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-001i-9300000000-71a42721119dc4209a6f	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-001i-9100000000-f588e80a7fdccf35f2e1	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-00di-0109600000-acd2c9f9fca4c7cfba95	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-0081-0391800000-02ac92fdae4a01b4c2a5	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-03di-0941100000-2ee943633f80ef05ad20	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-01p5-5910000000-24485d3a50477c04d448	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-014i-2910100000-073185881f64677cc7cf	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-0006-9232200000-e15db334adc612527ec9	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-0udi-3590000000-8facb1da5a7b9dc545a4	Not Available	View Spectrum

Toxicity Profile

Mechanism of Toxicity

Not Available

Carcinogenicity (IARC Classification)

Not Available

Minimum Risk Level

Not Available

Symptoms

Not Available

Treatment

Not Available

Toxicity Values

Toxicity Value	Unit	Value Range	Organism	Dose Descriptor	Route of Exposure	Predicted or Experimental	Reference
6064.0	Log mg/kg	[3400:11000]	Rat	LD50	oral	predicted	Not Available

Health Effects

Health Effect	Relationship	Direction	Reference

Exposure Sources

Source ID	Source	Sector	Reference
233	Brushes	Personal care & cosmetics	Not Available
306	Antibiotics	Healthcare, pharmaceuticals & veterinary products	Not Available
499	Roofs	Building & Construction	Not Available
503	Tents Or Canopies	Building & Construction	Not Available
505	Amplifiers	Electrical & Electronic Equipment	Not Available
506	Antennas	Electrical & Electronic Equipment	Not Available
507	Auxiliary Devices	Electrical & Electronic Equipment	Not Available
509	Colour Television Systems	Electrical & Electronic Equipment	Not Available
510	Communication Cables Or Conductors	Electrical & Electronic Equipment	Not Available
514	Discharge Lamps	Electrical & Electronic Equipment	Not Available
518	Electrically Stimulated Smoking Devices	Electrical & Electronic Equipment	Not Available
525	Line Transmission Systems	Electrical & Electronic Equipment	Not Available
530	Radio Transmission Systems	Electrical & Electronic Equipment	Not Available
534	Still Video Cameras	Electrical & Electronic Equipment	Not Available
535	Superconducting Magnets And Superconducting Coils	Electrical & Electronic Equipment	Not Available
537	Television Systems	Electrical & Electronic Equipment	Not Available
539	Video Games	Electrical & Electronic Equipment	Not Available
613	Depilatories	Personal care & cosmetics	Not Available
627	Roulette Games	Recreation & sports surfaces	Not Available
631	Anthraquinone Dyes	Textiles, leather & furnishings	Not Available
633	Azo Dyes	Textiles, leather & furnishings	Not Available
650	Purses Luggage Hand Bags	Textiles, leather & furnishings	Not Available

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this synthetic chemical

Targets

Structure	Protein	UniProt ID	Organism	Relationship	Details
Click to view 3D structure	Heparanase	Q9Y251	Humans	Predicted (SEA)	357.484
Click to view 3D structure	N-acetyllactosaminide alpha-1,3-galactosyltransferase	P50127	Sus scrofa	Predicted (SEA)	206.534
Click to view 3D structure	Transient receptor potential cation channel subfamily V member 1	Q8NER1	Humans	Predicted (SEA)	6685.15
Click to view 3D structure	Voltage-gated inwardly rectifying potassium channel KCNH2	Q12809	Humans	Predicted (SEA)	7729.34
Click to view 3D structure	Cytochrome P450 3A4	P08684	Humans	Predicted (SEA)	7750.28
Click to view 3D structure	Platelet-activating factor receptor	Q62035	Mus musculus	Predicted (SEA)	203.498
Click to view 3D structure	Alpha-glucosidase MAL12	P53341	Saccharomyces cerevisiae S288c	Predicted (SEA)	69.1301
Click to view 3D structure	Chitin synthase 1	P08004	Saccharomyces cerevisiae S288c	Predicted (SEA)	24.7561
Click to view 3D structure	Gap junction alpha-1 protein	P17302	Humans	Predicted (SEA)	0.544945
Click to view 3D structure	Gap junction beta-2 protein	P29033	Humans	Predicted (SEA)	0.856341
Click to view 3D structure	Human immunodeficiency virus type 1 REV	Q77Y21	Human immunodeficiency virus 1	Predicted (SEA)	0.778492
Click to view 3D structure	Beta-ketoacyl-[acyl-carrier-protein] synthase III	P0A6R0	Escherichia coli (strain K12)	Predicted (SEA)	1.63483
Click to view 3D structure	3-oxoacyl-[acyl-carrier-protein] synthase 3	C3TDZ2	Escherichia coli	Predicted (SEA)	2.33548
Click to view 3D structure	Asialoglycoprotein receptor 1	P07306	Humans	Predicted (SEA)	22.6541
Click to view 3D structure	Acidic phospholipase A2 2	P15445	Naja naja	Predicted (SEA)	7.47353
Click to view 3D structure	Alpha-amylase	Q7M328	Sus scrofa domesticus	Predicted (SEA)	20.3965
Click to view 3D structure	DNA topoisomerase 2-alpha	P11388	Humans	Predicted (SEA)	1744.99
Click to view 3D structure	DIS3-like exonuclease 2	Q8IYB7	Humans	Predicted (SEA)	8.25202
Click to view 3D structure	Maltase-glucoamylase	O43451	Humans	Predicted (SEA)	297.851
Click to view 3D structure	Phospholipase A2, membrane associated	P14555	Humans	Predicted (SEA)	3954.27
Click to view 3D structure	Aminoglycoside acetyltransferase	Q70E71	Enterococcus durans	Predicted (SEA)	60.5667
Click to view 3D structure	Streptokinase A	P10520	Streptococcus pyogenes serotype M1	Predicted (SEA)	7279.29
Click to view 3D structure	Phospholipase A2	P00630	Apis mellifera	Predicted (SEA)	27.7922
Click to view 3D structure	CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1	P54751	Mus musculus	Predicted (SEA)	24.8339
Click to view 3D structure	Sucrase-isomaltase, intestinal	P23739	Rattus norvegicus	Predicted (SEA)	70.2978