Honokiol (CED0003684)

Record Information
Version1.0
Creation Date2026-03-31 20:50:47 UTC
Update Date2026-08-19 23:59:51 UTC
SynCED IDCED0003684
Secondary Accession Numbers
  • CHEM057884
Identification
Common NameHonokiol
ClassSmall Molecule
Description
Honokiol is an organic compound with the formula C18H18O2 and an average molecular weight of 266.34 g/mol. Honokiol belongs to the biphenyls and derivatives, a subclass of benzene and substituted derivatives within the organic compounds. It is classified under the benzenoids superclass. In industrial contexts, the compound is utilized as a softener, conditioner, and bleaching agent. Biologically, it serves as an antioxidant and an analgesic (PMC9423984 ). The compound has been recorded in sources including electrical and electronic equipment auxiliary devices and healthcare, pharmaceuticals and veterinary products, specifically antibiotics. Recorded exposure routes include oral and inhalation. At the molecular level, honokiol acts as an inhibitor of three protein targets: Prostaglandin G/H synthase 1 (PTGS1), Prostaglandin G/H synthase 2 (PTGS2), and Polyunsaturated fatty acid 5-lipoxygenase (ALOX5). Regarding health effects, honokiol has a therapeutic effect on diabetic neuropathy (PMC13372820 ) and is associated with a decrease in lung cancer (PMC5666732 ).
Contaminant TypeNot Available
Chemical Structure
SynonymsNot Available
Chemical FormulaC18H18O2
Average Molecular Mass266.340 g/mol
Monoisotopic Mass266.131 g/mol
CAS Registry Number35354-74-6
IUPAC Name2-[4-hydroxy-3-(prop-2-en-1-yl)phenyl]-4-(prop-2-en-1-yl)phenol
Traditional Namehonokiol
SMILESOC1=C(CC=C)C=C(C=C1)C1=C(O)C=CC(CC=C)=C1
InChI IdentifierInChI=1S/C18H18O2/c1-3-5-13-7-9-18(20)16(11-13)14-8-10-17(19)15(12-14)6-4-2/h3-4,7-12,19-20H,1-2,5-6H2
InChI KeyFVYXIJYOAGAUQK-UHFFFAOYSA-N
Chemical Taxonomy
Description Belongs to the class of organic compounds known as biphenyls and derivatives. These are organic compounds containing to benzene rings linked together by a C-C bond.
KingdomOrganic compounds
Super ClassBenzenoids
ClassBenzene and substituted derivatives
Sub ClassBiphenyls and derivatives
Direct ParentBiphenyls and derivatives
Alternative Parents
Substituents
  • Biphenyl
  • 1-hydroxy-2-unsubstituted benzenoid
  • Phenol
  • Organic oxygen compound
  • Hydrocarbon derivative
  • Organooxygen compound
  • Aromatic homomonocyclic compound
Molecular FrameworkAromatic homomonocyclic compounds
External Descriptors
Biological Properties
StatusDetected and Not Quantified
OriginNot Available
Cellular LocationsNot Available
Biofluid LocationsNot Available
Tissue LocationsNot Available
ApplicationsNot Available
Biological Roles
Chemical RolesNot Available
Organoleptic EffectsNot Available
Physical Properties
StateNot Available
AppearanceNot Available
Experimental Properties
PropertyValue
Melting PointNot Available
Boiling PointNot Available
SolubilityNot Available
Predicted Properties
PropertyValueSource
Water Solubility0.0084 g/LALOGPS
logP4.7ALOGPS
logP5.21ChemAxon
logS-4.5ALOGPS
pKa (Strongest Acidic)8.84ChemAxon
pKa (Strongest Basic)-6ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count2ChemAxon
Hydrogen Donor Count2ChemAxon
Polar Surface Area40.46 ŲChemAxon
Rotatable Bond Count5ChemAxon
Refractivity83.73 m³·mol⁻¹ChemAxon
Polarizability30.17 ųChemAxon
Number of Rings2ChemAxon
BioavailabilityYesChemAxon
Rule of FiveNoChemAxon
Ghose FilterYesChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon
Spectra
Spectra
Spectrum TypeDescriptionSplash KeyDeposition DateView
Predicted GC-MSPredicted GC-MS Spectrumsplash10-002r-0090000000-d21034f533dcc0cc4201Not AvailableView Spectrum
Predicted GC-MSPredicted GC-MS SpectrumNot AvailableNot AvailableView Spectrum
Predicted GC-MSPredicted GC-MS SpectrumNot AvailableNot AvailableView Spectrum
Predicted GC-MSPredicted GC-MS SpectrumNot AvailableNot AvailableView Spectrum
Predicted GC-MSPredicted GC-MS SpectrumNot AvailableNot AvailableView Spectrum
Predicted GC-MSPredicted GC-MS SpectrumNot AvailableNot AvailableView Spectrum
Predicted GC-MSPredicted GC-MS SpectrumNot AvailableNot AvailableView Spectrum
Predicted GC-MSPredicted GC-MS SpectrumNot AvailableNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-014i-0490000000-a93db94aa7cc0f1eca67Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-014i-0090000000-45baa6bd1ec2da6ec7beNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-014i-0090000000-f144732517e114cd4bffNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-00dj-0890000000-a13969d1af5965ff5f44Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-014i-0090000000-b30550d3bb50bab86dfdNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-00di-0190000000-a2cfaa7a3e04201a9f70Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0uxu-0910000000-f0d77694f8eb15f271cdNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-052b-0940000000-c14721478c821cb46709Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-01b9-0090000000-93436b56def77ef80c45Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-00e9-1890000000-6969b61c744590d23394Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-014i-0090000000-de203782d6744284030eNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-00di-0190000000-07c1bcd75722df2481bbNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-014i-0090000000-d6300c7cf03b6ed3dfc5Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-00di-0190000000-031c834fe696a9b4ad30Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-00ea-0950000000-2eab0a2b980af8a68bc3Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-014i-0090000000-5b8b475ecc29254db72fNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-00di-0190000000-b1ddcde9d0c01c6b6dbcNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-014i-0090000000-c825886f22a9b93dbafbNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-014r-0390000000-721b2a72e28ca5589650Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-00di-0190000000-3bbcc0035d4b0ca55163Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0uxu-0910000000-fc83f570f8cf2306bb41Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0002-0940000000-7313e9b043fe2f269298Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-01si-0910000000-6ca3fada5d3b0e5ead60Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-00di-0190000000-e6cab5e7127cc8d42aefNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-016r-0900000000-0cb6b87ca15b6c7b3a9aNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0002-0930000000-b5cbbeb10530602d3c46Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-014i-0390000000-5759a6a7b41cc12c95f9Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-014i-0090000000-dc581aefda13099a7b18Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-014i-0290000000-6bbf50e8eb13905e13f4Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-00rb-0590000000-ab8c044625e8404a3c94Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-06ds-0690000000-52a903a33cc1130d38e0Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-014i-0090000000-49b99ae65a6ecc65d875Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-014r-0090000000-f907e06b8331140145c5Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-0c01-0590000000-aa81cc2fe90e305048eaNot AvailableView Spectrum
Toxicity Profile
Toxicity Values
Toxicity ValueOrganismDose DescriptorRoute of ExposurePredicted or ExperimentalToxicity RatingReference
2243.0 Log mg/kg [1300:4000]RatLD50oralpredictedNot AvailableNot Available
Toxicity / Toxin ClassNot Available
Mechanism of ToxicityNot Available
Carcinogenicity (IARC Classification)Not Available
Minimum Risk LevelNot Available
SymptomsNot Available
TreatmentNot Available
Health Effects
Health EffectRelationshipDirectionDescriptionReference
lung cancerAssociated With?decreaseA respiratory system cancer that is located in the lung. (DO)PMC5666732
inflammationHas Therapeutic Effect OnNot AvailableNot AvailablePMC9252012
cancerHas Therapeutic Effect OnNot AvailableCancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. Possible signs and symptoms include a lump, abnormal bleeding, prolonged cough, unexplained weight loss, and a change in bowel movements. There are over 100 types of cancers affect humans. The risk of developing certain cancers can be reduced by not smoking, maintaining a healthy weight, not drinking too much alcohol, eating plenty of vegetables, fruits and whole grains, vaccination against certain infectious diseases, not eating too much processed and red meat and avoiding too much sunlight exposure. Cancer is often treated with some combination of radiation therapy, surgery, chemotherapy and targeted therapy. The majority of cancers, some 90–95% of cases, are due to genetic mutations from environmental and lifestyle factors. The remaining 5–10% are due to inherited genetics.PMC10975327
breast cancerNot AvailableNot AvailableA breast cancer that has material basis in abnormally proliferating cells derives from epithelial cells. (DO)PMC10459502
strokeNot AvailableNot AvailableNot AvailablePMC2690856 , PMC2690856
feverNot AvailableNot AvailableA disorder characterized by an abnormally high body temperature.PMC2690856
headacheNot AvailableNot AvailableA disorder characterized by a sensation of marked discomfort in various parts of the head, not confined to the area of distribution of any nerve. (NCI CTCAE)PMC2690856
melanomaHas Therapeutic Effect OnNot AvailableA cell type cancer that has material basis in abnormally proliferating cells derives from melanocytes which are found in skin, the bowel and the eye. (DO)PMC6627480
Hepatocellular carcinomaHas Therapeutic Effect OnNot AvailableA liver carcinoma that has material basis in undifferentiated hepatocytes. (DO)PMC6627480
neuropathyHas Therapeutic Effect OnNot AvailableA nervous system disease that is located in nerves or nerve cells. (do).PMC13372820
diabetic neuropathyHas Therapeutic Effect OnNot AvailableNot AvailablePMC13372820
pancreatic cancerHas Therapeutic Effect OnNot AvailableAn endocrine gland cancer located in the pancreas. (DO)PMC6627480
vitiligoHas Therapeutic Effect OnNot AvailableA hypersensitivity reaction type II disease that causes depigmentation of patches of skin resulting from loss of function or death of melanoctyes. (DO)PMC11306171
anxiety disorderNot AvailableNot AvailableNot AvailablePMC2690856 , PMC2690856
Oxidative StressHas Therapeutic Effect OnNot AvailableNot AvailablePMC8388864
Endoplasmic Reticulum StressHas Therapeutic Effect OnNot AvailableNot AvailablePMC8388864
gliomaHas Therapeutic Effect OnNot AvailableNot AvailablePMC6627480
neurotic disorderNot AvailableNot AvailableNot AvailablePMC2690856 , PMC2690856
Exposure Sources
Source IDSourceSectorReference
CEDs000010Insecticides?Insecticides are synthetic chemicals designed to control or eliminate insect pests that threaten crops and other agricultural products.Agriculture & land managementPubChem
CEDs000306Antibiotics?Antibiotics are synthetic or semi-synthetic compounds used to treat bacterial infections in humans and animals.Healthcare, pharmaceuticals & veterinary productsNot Available
CEDs000507Auxiliary Devices?Auxiliary devices, such as capacitors, transformers, and circuit breakers, are integral components in various electronic systems.Electrical & Electronic EquipmentPubChem
CEDs000518Electrically Stimulated Smoking Devices?Electrically stimulated smoking devices, commonly known as e-cigarettes or vape pens, utilize electrical components to heat a liquid solution, often containing nicotine, flavorings, and other additives, to produce an aerosol for inhalation.Electrical & Electronic EquipmentPubChem
CEDs000519Electrodes?Electrodes, used in various electrical and electronic applications, can be a source of synthetic chemical contamination due to the materials from which they are constructed and the processes involved in their manufacturing.Electrical & Electronic EquipmentPubChem
CEDs000545Food Preservation?Food preservation often involves the use of synthetic chemicals, such as preservatives, flavor enhancers, and color additives, to extend shelf life and enhance the sensory qualities of food products.Food, food processing & cookwarePubChem
CEDs000561Perfumes Within Detergents And Soaps?Perfumes within detergents and soaps are synthetic fragrance compounds added to enhance the sensory experience of cleaning products.Household cleaning & consumer productsPubChem
CEDs000563Soap Detergents?Soap detergents are synthetic surfactants designed to enhance the cleaning efficacy of water by reducing surface tension, allowing for better interaction with dirt and grease.Household cleaning & consumer productsPubChem
CEDs000580Manufacture Preparation Of Tobacco Products?The manufacture and preparation of tobacco products involve various processes that can result in the introduction of synthetic chemicals into the environment.Industrial manufacturing & chemical processingPubChem
CEDs000606Plant Growth Regulators?Plant Growth Regulators (PGRs) are synthetic chemicals designed to influence the growth and development of plants.Agriculture & land managementPubChem
CEDs000609Aftershave?Aftershave is a grooming product typically used to soothe and protect the skin following shaving.Personal care & cosmeticsPubChem
CEDs000610Aftersun Products?Aftersun products are designed to soothe and hydrate the skin after sun exposure, often containing various synthetic chemicals such as emollients, preservatives, and fragrances.Personal care & cosmeticsPubChem
CEDs000611Anti Perspirants Or Body Deoderants?Antiperspirants and body deodorants commonly contain synthetic chemicals such as aluminum compounds, parabens, and synthetic fragrances.Personal care & cosmeticsPubChem
CEDs000613Depilatories?Depilatories are products designed to remove unwanted hair through the application of synthetic chemicals that break down the protein structure of hair, facilitating its removal.Personal care & cosmeticsPubChem
CEDs000614Essential Oils Or Perfumes?Essential oils and perfumes are complex mixtures of volatile compounds derived from natural or synthetic sources, commonly used for their aromatic properties.Personal care & cosmeticsPubChem
CEDs000615Eye Makeup Products?Eye makeup products, including mascaras, eyeliners, and eyeshadows, often contain a variety of synthetic chemicals such as pigments, preservatives, and film-forming agents.Personal care & cosmeticsPubChem
CEDs000617Lip Care Products?Lip care products, including lipsticks, balms, and glosses, often contain a variety of synthetic chemicals such as parabens, phthalates, and synthetic fragrances.Personal care & cosmeticsPubChem
CEDs000618Lip Makeup Products?Lip makeup products, such as lipsticks, lip glosses, and lip liners, often contain a variety of synthetic chemicals, including pigments, preservatives, and emollients.Personal care & cosmeticsPubChem
CEDs000678Nitrogenous Fertilisers?Nitrogenous fertilizers are synthetic chemical compounds primarily used to enhance plant growth by supplying essential nitrogen, a crucial nutrient for photosynthesis and protein synthesis.Agriculture & land managementPubChem
CEDs000679Phosphatic Fertilisers?Phosphatic fertilizers are synthetic chemical products primarily composed of phosphorus, which is essential for plant growth.Agriculture & land managementPubChem
CEDs000696Nanotechnology?Nanotechnology involves the manipulation of materials at the molecular or atomic level, typically within the range of 1 to 100 nanometers.Industrial manufacturing & chemical processingPubChem
CEDs000739Inks?Inks are complex mixtures composed of pigments or dyes, solvents, resins, and additives used primarily for printing and writing applications.Paper, pulp & fiber productsPubChem
CEDs000741Pigment Pastes?Pigment pastes are concentrated dispersions of pigments used to impart color and properties to materials.Paper, pulp & fiber productsPubChem
CEDs000744Water, Wastewater, & Sewage Treatment?Water, wastewater, and sewage treatment processes are critical for managing and mitigating pollutants in water systems.Wastewater, sanitation & biosolidsPubChem
Pathways
0 pathwaysPathway Source: PathBank

No pathways found

No metabolic pathways have been associated with this synthetic chemical

Targets
StructureProteinUniProt IDOrganismRelationshipDetails
Cannabinoid receptor 2 structureClick to view 3D structureCannabinoid receptor 2P34972HumansPredicted (SEA)
Prediction Confidence Score
0.63
Applicability Domain
1.0
Statistical Significance
1.80e-04
Supporting Reference Compounds
175
E-value
1.40129
Click to view 3D structureProstaglandin G/H synthase 2P79208Ovis ariesPredicted (SEA)
Prediction Confidence Score
0.605
Applicability Domain
1.0
Statistical Significance
1.00e-05
Supporting Reference Compounds
50
E-value
0.0778492
Polyunsaturated fatty acid 5-lipoxygenase structureClick to view 3D structurePolyunsaturated fatty acid 5-lipoxygenaseP09917HumansPredicted (SEA)
Prediction Confidence Score
0.6
Applicability Domain
1.0
Statistical Significance
1.20e-04
Supporting Reference Compounds
182
E-value
0.934191
Prostaglandin G/H synthase 1 structureClick to view 3D structureProstaglandin G/H synthase 1P05979Ovis ariesPredicted (SEA)
Prediction Confidence Score
0.585
Applicability Domain
1.0
Statistical Significance
6.00e-05
Supporting Reference Compounds
106
E-value
0.467095
Cannabinoid receptor 1 structureClick to view 3D structureCannabinoid receptor 1P21554HumansPredicted (SEA)
Prediction Confidence Score
0.443
Applicability Domain
1.0
Statistical Significance
0.0021
Supporting Reference Compounds
200
E-value
16.1926
Click to view 3D structureNeuraminidaseB4URF0Influenza A virusPredicted (SEA)
Prediction Confidence Score
0.354
Applicability Domain
1.0
Statistical Significance
7.60e-04
Supporting Reference Compounds
42
E-value
5.91654
NAD-dependent protein deacetylase sirtuin-3, mitochondrial structureClick to view 3D structureNAD-dependent protein deacetylase sirtuin-3, mitochondrialQ9NTG7HumansPredicted (SEA)
Prediction Confidence Score
0.293
Applicability Domain
1.0
Statistical Significance
4.70e-04
Supporting Reference Compounds
23
E-value
3.65891
High affinity choline transporter 1 structureClick to view 3D structureHigh affinity choline transporter 1Q9GZV3HumansPredicted (SEA)
Prediction Confidence Score
0.291
Applicability Domain
0.688
Statistical Significance
0.005
Supporting Reference Compounds
75
E-value
38.6132
Peroxisome proliferator-activated receptor gamma structureClick to view 3D structurePeroxisome proliferator-activated receptor gammaP37231HumansPredicted (SEA)
Prediction Confidence Score
0.277
Applicability Domain
0.688
Statistical Significance
0.0365
Supporting Reference Compounds
192
E-value
283.994
HTH-type transcriptional regulator MgrA structureClick to view 3D structureHTH-type transcriptional regulator MgrAP0C1S0Staphylococcus aureusPredicted (SEA)
Prediction Confidence Score
0.256
Applicability Domain
0.256 Low confidence
Statistical Significance
0.0018
Supporting Reference Compounds
1
E-value
14.4021
Carbonic anhydrase 2 structureClick to view 3D structureCarbonic anhydrase 2P00918HumansPredicted (SEA)
Prediction Confidence Score
0.242
Applicability Domain
0.265 Low confidence
Statistical Significance
0.21
Supporting Reference Compounds
472
E-value
1635.15
Click to view 3D structurePolyunsaturated fatty acid lipoxygenase ALOX15P16050HumansPredicted (SEA)
Prediction Confidence Score
0.241
Applicability Domain
0.282 Low confidence
Statistical Significance
0.0114
Supporting Reference Compounds
46
E-value
89.1374
Insulin-like growth factor 1 receptor structureClick to view 3D structureInsulin-like growth factor 1 receptorP08069HumansPredicted (SEA)
Prediction Confidence Score
0.238
Applicability Domain
0.282 Low confidence
Statistical Significance
0.4302
Supporting Reference Compounds
785
E-value
3349.31
Carbonic anhydrase 1 structureClick to view 3D structureCarbonic anhydrase 1P00915HumansPredicted (SEA)
Prediction Confidence Score
0.234
Applicability Domain
0.265 Low confidence
Statistical Significance
0.2223
Supporting Reference Compounds
407
E-value
1730.9
Zinc finger protein mex-5 structureClick to view 3D structureZinc finger protein mex-5Q9XUB2Caenorhabditis elegansPredicted (SEA)
Prediction Confidence Score
0.23
Applicability Domain
0.262 Low confidence
Statistical Significance
0.0234
Supporting Reference Compounds
88
E-value
182.245
Transthyretin structureClick to view 3D structureTransthyretinP02766HumansPredicted (SEA)
Prediction Confidence Score
0.229
Applicability Domain
0.265 Low confidence
Statistical Significance
0.0299
Supporting Reference Compounds
55
E-value
232.847
Polyunsaturated fatty acid lipoxygenase ALOX15 structureClick to view 3D structurePolyunsaturated fatty acid lipoxygenase ALOX15P12530Oryctolagus cuniculusPredicted (SEA)
Prediction Confidence Score
0.228
Applicability Domain
0.262 Low confidence
Statistical Significance
0.0163
Supporting Reference Compounds
47
E-value
126.816
D(2) dopamine receptor structureClick to view 3D structureD(2) dopamine receptorP14416HumansPredicted (SEA)
Prediction Confidence Score
0.225
Applicability Domain
0.268 Low confidence
Statistical Significance
0.5612
Supporting Reference Compounds
1103
E-value
4369.21
Aspartyl aminopeptidase structureClick to view 3D structureAspartyl aminopeptidaseQ8I2J3Plasmodium falciparum 3D7Predicted (SEA)
Prediction Confidence Score
0.224
Applicability Domain
0.262 Low confidence
Statistical Significance
0.0086
Supporting Reference Compounds
35
E-value
66.7168
D(3) dopamine receptor structureClick to view 3D structureD(3) dopamine receptorP35462HumansPredicted (SEA)
Prediction Confidence Score
0.224
Applicability Domain
0.268 Low confidence
Statistical Significance
0.5209
Supporting Reference Compounds
861
E-value
4055.56
Replicase polyprotein 1ab structureClick to view 3D structureReplicase polyprotein 1abP0DTD1SARS-CoV-2Predicted (SEA)
Prediction Confidence Score
0.223
Applicability Domain
0.262 Low confidence
Statistical Significance
0.1655
Supporting Reference Compounds
215
E-value
1288.64
Alpha-synuclein structureClick to view 3D structureAlpha-synucleinP37840HumansPredicted (SEA)
Prediction Confidence Score
0.223
Applicability Domain
0.268 Low confidence
Statistical Significance
0.0126
Supporting Reference Compounds
38
E-value
98.0122
Click to view 3D structure17-beta-hydroxysteroid dehydrogenase type 2P37059HumansPredicted (SEA)
Prediction Confidence Score
0.221
Applicability Domain
0.262 Low confidence
Statistical Significance
0.0326
Supporting Reference Compounds
44
E-value
254.178
D(4) dopamine receptor structureClick to view 3D structureD(4) dopamine receptorP21917HumansPredicted (SEA)
Prediction Confidence Score
0.221
Applicability Domain
0.268 Low confidence
Statistical Significance
0.4447
Supporting Reference Compounds
524
E-value
3462.19
Carbonic anhydrase 12 structureClick to view 3D structureCarbonic anhydrase 12O43570HumansPredicted (SEA)
Prediction Confidence Score
0.22
Applicability Domain
0.25 Low confidence
Statistical Significance
0.2884
Supporting Reference Compounds
332
E-value
2245.25
Concentrations
Not Available
External Links
DrugBank IDNot Available
HMDB IDNot Available
FooDB IDNot Available
Phenol Explorer IDNot Available
KNApSAcK IDC00002609
BiGG IDNot Available
BioCyc IDNot Available
METLIN IDNot Available
PDB IDNot Available
Wikipedia LinkHonokiol
Chemspider IDNot Available
ChEBI IDNot Available
PubChem Compound ID72303
Kegg Compound IDC10630
YMDB IDNot Available
ECMDB IDNot Available
References
Synthesis ReferenceNot Available
MSDSNot Available
General ReferencesNot Available