Myxothiazol (CED0007506)

Record Information

Version

1.0

Creation Date

2026-03-31 20:51:15 UTC

Update Date

2026-08-22 05:24:32 UTC

SynCED ID

CED0007506

Secondary Accession Numbers

CHEM057887

Identification

Common Name

Myxothiazol

Class

Small Molecule

Description

Myxothiazol is an organoheterocyclic compound with the formula C25H33N3O3S2 and an average molecular weight of 487.68 g/mol. Myxothiazol belongs to the thiazoles, a subclass of azoles within the organic compounds. It is found in or released from one recorded source: healthcare, pharmaceuticals & veterinary products (antibiotics), with recorded exposure routes via oral or inhalation. The compound has one recorded protein target, which is the mitochondrial cytochrome b-c1 complex subunit 1 (UQCRC1).

Contaminant Type

Not Available

Chemical Structure

MOL SDF PDB SMILES InChI

Synonyms

Not Available

Chemical Formula

C₂₅H₃₃N₃O₃S₂

Average Molecular Mass

487.680 g/mol

Monoisotopic Mass

487.196 g/mol

CAS Registry Number

76706-55-3

IUPAC Name

Not Available

Traditional Name

Not Available

SMILES

CO[C@@H](\C=C\C1=CSC(=N1)C1=CSC(=N1)[C@@H](C)\C=C\C=C\C(C)C)[C@@H](C)C(\OC)=C/C(N)=O

InChI Identifier

InChI=1S/C25H33N3O3S2/c1-16(2)9-7-8-10-17(3)24-28-20(15-33-24)25-27-19(14-32-25)11-12-21(30-5)18(4)22(31-6)13-23(26)29/h7-18,21H,1-6H3,(H2,26,29)/b9-7+,10-8+,12-11+,22-13+/t17-,18+,21-/m0/s1

InChI Key

XKTFQMCPGMTBMD-FYHMSGCOSA-N

Chemical Taxonomy

Classification

Not classified

Biological Properties

Status

Detected and Not Quantified

Origin

Not Available

Cellular Locations

Not Available

Biofluid Locations

Not Available

Tissue Locations

Not Available

Applications

Not Available

Biological Roles

Not Available

Chemical Roles

Not Available

Organoleptic Effects

Not Available

Physical Properties

State

Not Available

Appearance

Not Available

Experimental Properties

Property	Value
Melting Point	Not Available
Boiling Point	Not Available
Solubility	Not Available

Predicted Properties

Not Available

Spectra

Spectrum Type	Description	Splash Key	Deposition Date	View
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-059i-0410900000-0790ff1ac8bafd4be079	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-0kmi-2121900000-81c010d36a61a303b9a5	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-0feu-6920000000-9223e651633d68f162f5	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-05gs-1373900000-b730d60c207ec768dac3	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-002f-3471900000-b81a3bb12134c71aed03	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-0mw9-7900000000-f3e8630e8c89773133df	Not Available	View Spectrum

Toxicity Profile

Toxicity Values

Toxicity Value	Organism	Dose Descriptor	Route of Exposure	Predicted or Experimental	Toxicity Rating	Reference
3838.0 Log mg/kg [2200:6800]	Rat	LD50	oral	predicted	Not Available	Not Available

Toxicity / Toxin Class

Not Available

Mechanism of Toxicity

Not Available

Carcinogenicity (IARC Classification)

Not Available

Minimum Risk Level

Not Available

Symptoms

Not Available

Treatment

Not Available

Health Effects

Health Effect	Relationship	Direction	Description	Reference

Exposure Sources

Source ID	Source	Sector	Reference
CEDs000010	Insecticides?Insecticides are synthetic chemicals designed to control or eliminate insect pests that threaten crops and other agricultural products.	Agriculture & land management	PubChem
CEDs000306	Antibiotics?Antibiotics are synthetic or semi-synthetic compounds used to treat bacterial infections in humans and animals.	Healthcare, pharmaceuticals & veterinary products	Not Available
CEDs000524	Hybrid Capacitors?Hybrid capacitors are energy storage devices that combine the properties of electrolytic and supercapacitors, utilizing a combination of electrochemical principles to achieve higher energy density and power density.	Electrical & Electronic Equipment	PubChem
CEDs000545	Food Preservation?Food preservation often involves the use of synthetic chemicals, such as preservatives, flavor enhancers, and color additives, to extend shelf life and enhance the sensory qualities of food products.	Food, food processing & cookware	PubChem
CEDs000596	Acaricides?Acaricides are synthetic chemicals specifically designed to target and control mite populations that can damage crops and plants.	Agriculture & land management	PubChem
CEDs000696	Nanotechnology?Nanotechnology involves the manipulation of materials at the molecular or atomic level, typically within the range of 1 to 100 nanometers.	Industrial manufacturing & chemical processing	PubChem
CEDs000739	Inks?Inks are complex mixtures composed of pigments or dyes, solvents, resins, and additives used primarily for printing and writing applications.	Paper, pulp & fiber products	PubChem

Pathways

0 pathwaysPathway Source: PathBank

No pathways found

No metabolic pathways have been associated with this synthetic chemical

Targets

Structure	Protein	UniProt ID	Organism	Relationship	Details
Click to view 3D structure	Capsid scaffolding protein	P03234	HHV-4	Predicted (SEA)	Prediction Confidence Score 0.2 Applicability Domain 0.2 Low confidence Statistical Significance 0.0106 Supporting Reference Compounds 1 E-value 82.2088
Click to view 3D structure	Capsid scaffolding protein	P24433	Human herpesvirus 6A (strain Uganda-1102) (HHV-6 variant A) (Human Blymphotropic virus)	Predicted (SEA)	Prediction Confidence Score 0.197 Applicability Domain 0.2 Low confidence Statistical Significance 0.0071 Supporting Reference Compounds 2 E-value 55.3508
Click to view 3D structure	Fe(3+)-pyochelin receptor	P42512	Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)	Predicted (SEA)	Prediction Confidence Score 0.193 Applicability Domain 0.193 Low confidence Statistical Significance 0.007 Supporting Reference Compounds 1 E-value 54.1831
Click to view 3D structure	Rho-associated protein kinase 1	Q13464	Humans	Predicted (SEA)	Prediction Confidence Score 0.19 Applicability Domain 0.202 Low confidence Statistical Significance 0.8987 Supporting Reference Compounds 834 E-value 6996.0
Click to view 3D structure	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	P48736	Humans	Predicted (SEA)	Prediction Confidence Score 0.19 Applicability Domain 0.2 Low confidence Statistical Significance 0.7719 Supporting Reference Compounds 450 E-value 6009.1
Click to view 3D structure	Mitogen-activated protein kinase 8	P45983	Humans	Predicted (SEA)	Prediction Confidence Score 0.189 Applicability Domain 0.202 Low confidence Statistical Significance 0.9056 Supporting Reference Compounds 782 E-value 7049.79
Click to view 3D structure	cAMP-dependent protein kinase catalytic subunit alpha	P17612	Humans	Predicted (SEA)	Prediction Confidence Score 0.188 Applicability Domain 0.202 Low confidence Statistical Significance 0.9031 Supporting Reference Compounds 735 E-value 7030.33
Click to view 3D structure	Cytochrome P450 2C9	P11712	Humans	Predicted (SEA)	Prediction Confidence Score 0.188 Applicability Domain 0.208 Low confidence Statistical Significance 0.968 Supporting Reference Compounds 1245 E-value 7535.96
Click to view 3D structure	Capsid scaffolding protein	P89449	Human herpesvirus 2 (strain HG52) (HHV-2) (Human herpes simplex virus2)	Predicted (SEA)	Prediction Confidence Score 0.187 Applicability Domain 0.2 Low confidence Statistical Significance 0.0098 Supporting Reference Compounds 4 E-value 76.0587
Click to view 3D structure	Histone deacetylase 3	O15379	Humans	Predicted (SEA)	Prediction Confidence Score 0.187 Applicability Domain 0.229 Low confidence Statistical Significance 0.7295 Supporting Reference Compounds 257 E-value 5679.18
Click to view 3D structure	Aurora kinase B	Q96GD4	Humans	Predicted (SEA)	Prediction Confidence Score 0.187 Applicability Domain 0.202 Low confidence Statistical Significance 0.9216 Supporting Reference Compounds 1017 E-value 7174.27
Click to view 3D structure	Cytochrome P450 3A4	P08684	Humans	Predicted (SEA)	Prediction Confidence Score 0.187 Applicability Domain 0.196 Low confidence Statistical Significance 0.9764 Supporting Reference Compounds 1538 E-value 7601.35
Click to view 3D structure	Glycogen synthase kinase-3 beta	P49841	Humans	Predicted (SEA)	Prediction Confidence Score 0.186 Applicability Domain 0.202 Low confidence Statistical Significance 0.9441 Supporting Reference Compounds 1157 E-value 7349.9
Click to view 3D structure	Proto-oncogene tyrosine-protein kinase receptor Ret	P07949	Humans	Predicted (SEA)	Prediction Confidence Score 0.186 Applicability Domain 0.202 Low confidence Statistical Significance 0.9107 Supporting Reference Compounds 764 E-value 7090.04
Click to view 3D structure	5'-AMP-activated protein kinase catalytic subunit alpha-1	Q13131	Humans	Predicted (SEA)	Prediction Confidence Score 0.186 Applicability Domain 0.202 Low confidence Statistical Significance 0.8887 Supporting Reference Compounds 596 E-value 6918.3
Click to view 3D structure	Tyrosine-protein kinase Lck	P06239	Humans	Predicted (SEA)	Prediction Confidence Score 0.186 Applicability Domain 0.202 Low confidence Statistical Significance 0.9486 Supporting Reference Compounds 1130 E-value 7384.54
Click to view 3D structure	Dual specificity protein kinase CLK2	P49760	Humans	Predicted (SEA)	Prediction Confidence Score 0.185 Applicability Domain 0.202 Low confidence Statistical Significance 0.9098 Supporting Reference Compounds 727 E-value 7083.03
Click to view 3D structure	Receptor-type tyrosine-protein kinase FLT3	P36888	Humans	Predicted (SEA)	Prediction Confidence Score 0.185 Applicability Domain 0.202 Low confidence Statistical Significance 0.9388 Supporting Reference Compounds 1274 E-value 7308.41
Click to view 3D structure	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	P42336	Humans	Predicted (SEA)	Prediction Confidence Score 0.185 Applicability Domain 0.194 Low confidence Statistical Significance 0.8475 Supporting Reference Compounds 536 E-value 6597.8
Click to view 3D structure	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	P42338	Humans	Predicted (SEA)	Prediction Confidence Score 0.185 Applicability Domain 0.194 Low confidence Statistical Significance 0.7953 Supporting Reference Compounds 372 E-value 6191.5
Click to view 3D structure	Cyclin-dependent kinase 2	P24941	Humans	Predicted (SEA)	Prediction Confidence Score 0.185 Applicability Domain 0.202 Low confidence Statistical Significance 0.9319 Supporting Reference Compounds 1029 E-value 7254.46
Click to view 3D structure	Vascular endothelial growth factor receptor 2	P35968	Humans	Predicted (SEA)	Prediction Confidence Score 0.185 Applicability Domain 0.202 Low confidence Statistical Significance 0.9506 Supporting Reference Compounds 1660 E-value 7400.58
Click to view 3D structure	Death-associated protein kinase 3	O43293	Humans	Predicted (SEA)	Prediction Confidence Score 0.185 Applicability Domain 0.202 Low confidence Statistical Significance 0.8949 Supporting Reference Compounds 599 E-value 6966.42
Click to view 3D structure	Tyrosine-protein kinase JAK2	O60674	Humans	Predicted (SEA)	Prediction Confidence Score 0.185 Applicability Domain 0.202 Low confidence Statistical Significance 0.9362 Supporting Reference Compounds 1022 E-value 7287.93
Click to view 3D structure	Serine/threonine-protein kinase pim-1	P11309	Humans	Predicted (SEA)	Prediction Confidence Score 0.185 Applicability Domain 0.202 Low confidence Statistical Significance 0.9313 Supporting Reference Compounds 967 E-value 7250.33