6-Diazo-5-oxo-L-norleucine (CED0007175)

Record Information

Version

1.0

Creation Date

2026-03-31 21:03:00 UTC

Update Date

2026-08-23 16:07:41 UTC

Accession Number

CHEM057950

Identification

Common Name

6-Diazo-5-oxo-L-norleucine

Class

Small Molecule

Description

6-Diazo-5-oxo-L-norleucine (C6H9N3O3) is an organic compound with an average molecular weight of 171.16 g/mol. 6-Diazo-5-oxo-L-norleucine belongs to the amino acids, peptides, and analogues, a subclass of carboxylic acids and derivatives within the organic compounds. The compound is found in or released from two recorded sources: healthcare, pharmaceuticals & veterinary products (antibiotics) and household cleaning & consumer products (perfumes within detergents and soaps). Recorded exposure routes for this substance include oral and inhalation.

Contaminant Type

Not Available

Chemical Structure

MOL SDF PDB SMILES InChI

Synonyms

Value	Source
Diazooxonorleucine	MeSH

Chemical Formula

C₆H₉N₃O₃

Average Molecular Mass

171.156 g/mol

Monoisotopic Mass

171.064 g/mol

CAS Registry Number

157-03-9

IUPAC Name

Not Available

Traditional Name

Not Available

SMILES

N[C@@H](CCC(=O)C=[N+]=[N-])C(O)=O

InChI Identifier

InChI=1S/C6H9N3O3/c7-5(6(11)12)2-1-4(10)3-9-8/h3,5H,1-2,7H2,(H,11,12)/t5-/m0/s1

InChI Key

YCWQAMGASJSUIP-YFKPBYRVSA-N

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as l-alpha-amino acids. These are alpha amino acids which have the L-configuration of the alpha-carbon atom.

Kingdom

Organic compounds

Super Class

Organic acids and derivatives

Class

Carboxylic acids and derivatives

Sub Class

Amino acids, peptides, and analogues

Direct Parent

L-alpha-amino acids

Alternative Parents

Substituents

L-alpha-amino acid
Medium-chain fatty acid
Amino fatty acid
Gamma-aminoketone
Alpha-diazo ketone
Fatty acid
Fatty acyl
Amino acid
Diazo compound
Ketone
Carboxylic acid
Monocarboxylic acid or derivatives
Organic nitrogen compound
Organic oxygen compound
Primary amine
Organooxygen compound
Organonitrogen compound
Amine
Primary aliphatic amine
Organic zwitterion
Organic salt
Carbonyl group
Organic oxide
Hydrocarbon derivative
Aliphatic acyclic compound

Molecular Framework

Aliphatic acyclic compounds

External Descriptors

Not Available

Biological Properties

Status

Detected and Not Quantified

Origin

Not Available

Cellular Locations

Not Available

Biofluid Locations

Not Available

Tissue Locations

Not Available

Applications

Not Available

Biological Roles

Not Available

Chemical Roles

Not Available

Organoleptic Effects

Not Available

Physical Properties

State

Not Available

Appearance

Not Available

Experimental Properties

Property	Value
Melting Point	Not Available
Boiling Point	Not Available
Solubility	Not Available

Predicted Properties

Not Available

Spectra

Not Available

Toxicity Profile

Mechanism of Toxicity

Not Available

Carcinogenicity (IARC Classification)

Not Available

Minimum Risk Level

Not Available

Symptoms

Not Available

Treatment

Not Available

Toxicity Values

Toxicity Value	Unit	Value Range	Organism	Dose Descriptor	Route of Exposure	Predicted or Experimental	Reference
481.0	Log mg/kg	[270:850]	Rat	LD50	oral	predicted	Not Available

Health Effects

Health Effect	Relationship	Direction	Reference

Exposure Sources

Source ID	Source	Sector	Reference
306	Antibiotics	Healthcare, pharmaceuticals & veterinary products	Not Available
561	Perfumes Within Detergents And Soaps	Household cleaning & consumer products	Not Available

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this synthetic chemical

Targets

Structure	Protein	UniProt ID	Organism	Relationship	Details
Click to view 3D structure	Metabotropic glutamate receptor 8	P47743	Mus musculus	Predicted (SEA)	0.389246
Click to view 3D structure	Metabotropic glutamate receptor 2	P31421	Rattus norvegicus	Predicted (SEA)	3.26967
Click to view 3D structure	Metabotropic glutamate receptor 6	P35349	Rattus norvegicus	Predicted (SEA)	1.08989
Click to view 3D structure	Metabotropic glutamate receptor 4	P31423	Rattus norvegicus	Predicted (SEA)	3.42537
Click to view 3D structure	Metabotropic glutamate receptor 8	P70579	Rattus norvegicus	Predicted (SEA)	1.63483
Click to view 3D structure	Metabotropic glutamate receptor 6	O15303	Humans	Predicted (SEA)	2.25763
Click to view 3D structure	Asc-type amino acid transporter 1	P63116	Rat	Predicted (SEA)	0.934191
Click to view 3D structure	Excitatory amino acid transporter 3	P43005	Humans	Predicted (SEA)	2.17978
Click to view 3D structure	Metabotropic glutamate receptor 4	Q14833	Humans	Predicted (SEA)	10.1982
Click to view 3D structure	Arginase	Q8I384	Plasmodium falciparum	Predicted (SEA)	0.934191
Click to view 3D structure	Glutamate receptor ionotropic, kainate 1	P22756	Rattus norvegicus	Predicted (SEA)	1.94623
Click to view 3D structure	Betaine--homocysteine S-methyltransferase 1	Q93088	Humans	Predicted (SEA)	0.856341
Click to view 3D structure	Glutamate receptor ionotropic, kainate 3	P42264	Rattus norvegicus	Predicted (SEA)	2.02408
Click to view 3D structure	Glutamate receptor ionotropic, kainate 2	P42260	Rattus norvegicus	Predicted (SEA)	1.47914
Click to view 3D structure	Metabotropic glutamate receptor 8	O00222	Humans	Predicted (SEA)	2.72472
Click to view 3D structure	Glutamate receptor ionotropic, kainate 1	P39086	Humans	Predicted (SEA)	2.10193
Click to view 3D structure	Arginase-2, mitochondrial	P78540	Humans	Predicted (SEA)	0.778492
Click to view 3D structure	Metabotropic glutamate receptor 2	Q14416	Humans	Predicted (SEA)	13.5458
Click to view 3D structure	Metabotropic glutamate receptor 1	P23385	Rattus norvegicus	Predicted (SEA)	6.61718
Click to view 3D structure	Glutamine synthetase	P0A9C5	Escherichia coli K-12	Predicted (SEA)	1.40129
Click to view 3D structure	S-methylmethionine--homocysteine S-methyltransferase BHMT2	Q9H2M3	Humans	Predicted (SEA)	1.55698
Click to view 3D structure	Glutamate receptor ionotropic, kainate 2	Q13002	Humans	Predicted (SEA)	1.47914
Click to view 3D structure	Metabotropic glutamate receptor 3	P31422	Rattus norvegicus	Predicted (SEA)	5.13805
Click to view 3D structure	Glutamate receptor 4	P48058	Humans	Predicted (SEA)	1.79053
Click to view 3D structure	Glutamate receptor 2	P42262	Humans	Predicted (SEA)	2.49118