Myxin (CED0008848)

Record Information

Version

1.0

Creation Date

2026-03-31 21:07:36 UTC

Update Date

2026-08-18 22:27:19 UTC

Accession Number

CHEM057959

Identification

Common Name

Myxin

Class

Small Molecule

Description

Myxin is an organoheterocyclic compound with the formula C13H10N2O4 and an average molecular weight of 258.23 g/mol. Myxin belongs to the benzodiazines, a subclass of diazanaphthalenes within the organic compounds. This compound is found in or released from five recorded sources, including household items such as credit card holders and food, food processing, and cookware specifically in the treatment of hops. It is also associated with electrical and electronic equipment, including electric hearing aids and antennas, as well as healthcare, pharmaceuticals, and veterinary products in the form of antibiotics. Recorded exposure routes for myxin include oral and inhalation.

Contaminant Type

Not Available

Chemical Structure

MOL SDF PDB SMILES InChI

Synonyms

Value	Source
1-Hydroxy-6-methoxyphenazine-5,10-dioxide	MeSH

Chemical Formula

C₁₃H₁₀N₂O₄

Average Molecular Mass

258.230 g/mol

Monoisotopic Mass

258.064 g/mol

CAS Registry Number

13925-12-7

IUPAC Name

1-hydroxy-6-methoxyphenazine-5,10-diium-5,10-bis(olate)

Traditional Name

1-hydroxy-6-methoxyphenazine-5,10-diium-5,10-bis(olate)

SMILES

Not Available

InChI Identifier

InChI=1S/C13H10N2O4/c1-19-11-7-3-5-9-13(11)15(18)8-4-2-6-10(16)12(8)14(9)17/h2-7,16H,1H3

InChI Key

JIDVGUQUQSOHOL-UHFFFAOYSA-N

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as phenazines and derivatives. These are polycyclic aromatic compounds containing a phenazine moiety, which is a linear tricyclic system that consists of a two benzene rings joined by a pyrazine ring.

Kingdom

Organic compounds

Super Class

Organoheterocyclic compounds

Class

Diazanaphthalenes

Sub Class

Benzodiazines

Direct Parent

Phenazines and derivatives

Alternative Parents

Substituents

Phenazine
Anisole
Alkyl aryl ether
1-hydroxy-4-unsubstituted benzenoid
1-hydroxy-2-unsubstituted benzenoid
Pyrazine
Benzenoid
Pyrazinium
Heteroaromatic compound
Ether
Azacycle
Organic nitrogen compound
Hydrocarbon derivative
Organic oxide
Organooxygen compound
Organonitrogen compound
Organopnictogen compound
Organic oxygen compound
Aromatic heteropolycyclic compound

Molecular Framework

Aromatic heteropolycyclic compounds

External Descriptors

Not Available

Biological Properties

Status

Detected and Not Quantified

Origin

Not Available

Cellular Locations

Not Available

Biofluid Locations

Not Available

Tissue Locations

Not Available

Applications

Not Available

Biological Roles

Not Available

Chemical Roles

Not Available

Organoleptic Effects

Not Available

Physical Properties

State

Not Available

Appearance

Not Available

Experimental Properties

Property	Value
Melting Point	Not Available
Boiling Point	Not Available
Solubility	Not Available

Predicted Properties

Property	Value	Source
Water Solubility	0.24 g/L	ALOGPS
logP	-0.13	ALOGPS
logP	0.72	ChemAxon
logS	-3	ALOGPS
pKa (Strongest Acidic)	5.74	ChemAxon
pKa (Strongest Basic)	2.42	ChemAxon
Physiological Charge	-1	ChemAxon
Hydrogen Acceptor Count	4	ChemAxon
Hydrogen Donor Count	1	ChemAxon
Polar Surface Area	83.34 Å²	ChemAxon
Rotatable Bond Count	1	ChemAxon
Refractivity	69.22 m³·mol⁻¹	ChemAxon
Polarizability	24.83 Å³	ChemAxon
Number of Rings	3	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	Yes	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

Spectra

Spectrum Type	Description	Splash Key	Deposition Date	View
Predicted GC-MS	Predicted GC-MS Spectrum	splash10-0a5i-1890000000-c8485df08fd6c506c76a	Not Available	View Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum	Not Available	Not Available	View Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum	Not Available	Not Available	View Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum	Not Available	Not Available	View Spectrum
1D NMR	¹H NMR Spectrum (1D, D₂O, predicted)	Not Available	Not Available	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, D₂O, predicted)	Not Available	Not Available	View Spectrum

Toxicity Profile

Mechanism of Toxicity

Not Available

Carcinogenicity (IARC Classification)

Not Available

Minimum Risk Level

Not Available

Symptoms

Not Available

Treatment

Not Available

Toxicity Values

Toxicity Value	Unit	Value Range	Organism	Dose Descriptor	Route of Exposure	Predicted or Experimental	Reference
209.0	Log mg/kg	[120:370]	Rat	LD50	oral	predicted	Not Available

Health Effects

Health Effect	Relationship	Direction	Reference

Exposure Sources

Source ID	Source	Sector	Reference
306	Antibiotics	Healthcare, pharmaceuticals & veterinary products	Not Available
506	Antennas	Electrical & Electronic Equipment	Not Available
516	Electric Hearing Aids	Electrical & Electronic Equipment	Not Available
553	Treatment Of Hops	Food, food processing & cookware	Not Available
572	Credit Card Holders	Household items	Not Available

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this synthetic chemical

Targets

Structure	Protein	UniProt ID	Organism	Relationship	Details
Click to view 3D structure	Heat shock factor protein 1	P38532	Mus musculus	Predicted (SEA)	440.627
Click to view 3D structure	Transcription factor EB	P19484	Humans	Predicted (SEA)	32.7745
Click to view 3D structure	Streptokinase A	P10520	Streptococcus pyogenes serotype M1	Predicted (SEA)	923.992
Click to view 3D structure	Carbonic anhydrase 12	O43570	Humans	Predicted (SEA)	917.531
Click to view 3D structure	Carbonic anhydrase 9	Q16790	Humans	Predicted (SEA)	1084.44
Click to view 3D structure	Carbonic anhydrase 14	Q9ULX7	Humans	Predicted (SEA)	520.5
Click to view 3D structure	Mitochondrial import inner membrane translocase subunit TIM10	P87108	Saccharomyces cerevisiae S288c	Predicted (SEA)	217.277
Click to view 3D structure	Induced myeloid leukemia cell differentiation protein Mcl-1	Q07820	Humans	Predicted (SEA)	956.222
Click to view 3D structure	Estrogen receptor beta	Q92731	Humans	Predicted (SEA)	563.006
Click to view 3D structure	Protein RecA	P9WHJ3	Mycobacterium tuberculosis	Predicted (SEA)	999.195
Click to view 3D structure	Amine oxidase [flavin-containing] B	P27338	Humans	Predicted (SEA)	1268.63
Click to view 3D structure	Carbonic anhydrase 1	P00915	Humans	Predicted (SEA)	1367.97
Click to view 3D structure	Carbonic anhydrase 2	P00918	Humans	Predicted (SEA)	1625.34
Click to view 3D structure	Carbonic anhydrase 7	P43166	Humans	Predicted (SEA)	886.625
Click to view 3D structure	Large T antigen	P03070	Simian virus 40	Predicted (SEA)	132.188
Click to view 3D structure	ATP-dependent molecular chaperone HSP82	C4YTQ8	Candida albicans (strain WO-1) (Yeast)	Predicted (SEA)	760.82
Click to view 3D structure	5-hydroxytryptamine receptor 2C	P28335	Humans	Predicted (SEA)	2788.17
Click to view 3D structure	Mitochondrial import inner membrane translocase subunit TIM23	P32897	Saccharomyces cerevisiae S288c	Predicted (SEA)	406.139
Click to view 3D structure	Estrogen receptor	P03372	Humans	Predicted (SEA)	562.928
Click to view 3D structure	Tyrosine-protein kinase JAK2	O60674	Humans	Predicted (SEA)	3876.74
Click to view 3D structure	5-hydroxytryptamine receptor 2A	P28223	Humans	Predicted (SEA)	3323.15
Click to view 3D structure	Epidermal growth factor receptor	P00533	Humans	Predicted (SEA)	4323.98
Click to view 3D structure	5-hydroxytryptamine receptor 1A	P08908	Humans	Predicted (SEA)	3112.41
Click to view 3D structure	Broad substrate specificity ATP-binding cassette transporter ABCG2	Q9UNQ0	Humans	Predicted (SEA)	988.685
Click to view 3D structure	5-hydroxytryptamine receptor 7	P34969	Humans	Predicted (SEA)	2613.48