((2,2,3,3-Tetrafluoropropoxy)methyl)oxirane (CED0034525)

Record Information
Version1.0
Creation Date2026-04-03 05:27:31 UTC
Update Date2026-08-23 14:52:27 UTC
SynCED IDCED0034525
Secondary Accession Numbers
  • CHEM062020
Identification
Common Name((2,2,3,3-Tetrafluoropropoxy)methyl)oxirane
ClassSmall Molecule
Description
((2,2,3,3-Tetrafluoropropoxy)methyl)oxirane belongs to the epoxides, a class of organoheterocyclic compounds within the organic compounds. This compound has the chemical formula C6H8F4O2 and an average molecular weight of 188.12 g/mol. The substance is found in or released from 13 recorded sources across several sectors. In the electrical and electronic equipment sector, it is associated with cell phones, capacitors, batteries, printed circuit boards, wires and cables, and one additional source. It is found in the textiles, leather and furnishings sector within synthetic textiles as well as carpets and rugs. Within the energy, oil and gas sector and the industrial manufacturing and chemical processing sector, the compound is found in lubricants. Additionally, it is found in food packaging within the food, food processing and cookware sector, and in medical devices within the healthcare, pharmaceuticals and veterinary products sector. One further sector is also recorded as a source. Recorded exposure routes for this compound include oral, touch, and inhalation.
Contaminant Type
  • PFAS
Chemical Structure
SynonymsNot Available
Chemical FormulaC6H8F4O2
Average Molecular Mass188.122 g/mol
Monoisotopic Mass188.046 g/mol
CAS Registry Number19932-26-4
IUPAC NameNot Available
Traditional NameNot Available
SMILESFC(F)C(F)(F)COCC1CO1
InChI IdentifierInChI=1S/C6H8F4O2/c7-5(8)6(9,10)3-11-1-4-2-12-4/h4-5H,1-3H2
InChI KeyDATKALAKXGFGPI-UHFFFAOYSA-N
Chemical Taxonomy
ClassificationNot classified
Biological Properties
StatusDetected and Not Quantified
OriginNot Available
Cellular LocationsNot Available
Biofluid LocationsNot Available
Tissue LocationsNot Available
ApplicationsNot Available
Biological RolesNot Available
Chemical RolesNot Available
Organoleptic EffectsNot Available
Physical Properties
StateNot Available
AppearanceNot Available
Experimental Properties
PropertyValue
Melting PointNot Available
Boiling PointNot Available
SolubilityNot Available
Predicted PropertiesNot Available
Spectra
SpectraNot Available
Toxicity Profile
Toxicity Values
Toxicity ValueOrganismDose DescriptorRoute of ExposurePredicted or ExperimentalToxicity RatingReference
1344.0 Log mg/kg [760:2400]RatLD50oralpredictedNot AvailableNot Available
Toxicity / Toxin ClassNot Available
Mechanism of ToxicityNot Available
Carcinogenicity (IARC Classification)Not Available
Minimum Risk LevelNot Available
SymptomsNot Available
TreatmentNot Available
Health Effects
Health EffectRelationshipDirectionReference
Exposure Sources
Source IDSourceSectorReference
CEDs000007Pesticides?Pesticides are synthetic chemicals designed to prevent, destroy, or control pests that threaten crops and agricultural productivity.Agriculture & land managementNot Available
CEDs000120Wires and cables?Wires and cables are integral components in the transmission of electrical power and signals.Electrical & Electronic EquipmentNot Available
CEDs000121Printed circuit boards?Printed circuit boards (PCBs) are essential components in the manufacturing of electronic devices, serving as the backbone for electrical connections and circuit pathways.Electrical & Electronic EquipmentNot Available
CEDs000125Batteries?Batteries are devices that store and release electrical energy through electrochemical reactions.Electrical & Electronic EquipmentNot Available
CEDs000130Semiconductors?Semiconductors are materials that possess electrical conductivity between that of conductors and insulators, making them essential for various electronic applications, including transistors, diodes, and integrated circuits.Electrical & Electronic EquipmentNot Available
CEDs000138Lubricants?Lubricants are synthetic or petroleum-derived substances used to reduce friction between surfaces in machinery and equipment, enhancing operational efficiency and longevity.Energy, oil & gasNot Available
CEDs000147Food packaging?Food packaging often utilizes synthetic chemicals, such as plastics and coatings, to enhance durability, moisture resistance, and shelf life.Food, food processing & cookwareNot Available
CEDs000174Lubricants?Lubricants are synthetic or petroleum-based substances used to reduce friction and wear between moving parts in machinery and equipment.Industrial manufacturing & chemical processingNot Available
CEDs000234Medical devices?Medical devices often incorporate synthetic chemicals in their manufacturing processes, which can contribute to contamination in healthcare settings.Healthcare, pharmaceuticals & veterinary productsNot Available
CEDs000451Carpets and Rugs?Carpets and rugs are commonly manufactured using synthetic fibers such as nylon, polyester, and polypropylene, which can be derived from petrochemical sources.Textiles, leather & furnishingsNot Available
CEDs000454Synthetic textiles?Synthetic textiles are materials derived from man-made fibers, such as polyester, nylon, and acrylic, which are produced through chemical processes involving petrochemicals.Textiles, leather & furnishingsNot Available
CEDs000490Personal care & cosmeticsNot Available
CEDs000492Cell phones?Cell phones contain a variety of synthetic chemicals and materials, including plastics, metals, and glass, which can contribute to environmental contamination.Electrical & Electronic EquipmentNot Available
CEDs000493Capacitors?Capacitors are electronic components that store and release electrical energy, often using dielectric materials that can include synthetic chemicals.Electrical & Electronic EquipmentNot Available
CEDs000511Conductors Or Conductive Bodies Characterised By The Conductive Materials?Conductors, or conductive bodies, are materials that allow the flow of electrical current, typically made from metals such as copper, aluminum, or silver.Electrical & Electronic EquipmentNot Available
CEDs000519Electrodes?Electrodes, used in various electrical and electronic applications, can be a source of synthetic chemical contamination due to the materials from which they are constructed and the processes involved in their manufacturing.Electrical & Electronic EquipmentNot Available
CEDs000524Hybrid Capacitors?Hybrid capacitors are energy storage devices that combine the properties of electrolytic and supercapacitors, utilizing a combination of electrochemical principles to achieve higher energy density and power density.Electrical & Electronic EquipmentNot Available
CEDs000689Glass Fibres?Glass fibres are composed of fine strands of glass, commonly utilized for their tensile strength and lightweight properties.Building & ConstructionNot Available
CEDs000696Nanotechnology?Nanotechnology involves the manipulation of materials at the molecular or atomic level, typically within the range of 1 to 100 nanometers.Industrial manufacturing & chemical processingNot Available
CEDs000735Explosives?Explosives are chemical compounds or mixtures designed to undergo rapid decomposition, releasing energy in the form of gas and heat.Defense & military infrastructureNot Available
CEDs000739Inks?Inks are complex mixtures composed of pigments or dyes, solvents, resins, and additives used primarily for printing and writing applications.Paper, pulp & fiber productsNot Available
CEDs000743Sludge Treatment?Sludge treatment involves the processing of waste materials generated from wastewater treatment plants, which often contain a variety of organic and inorganic substances.Wastewater, sanitation & biosolidsNot Available
CEDs000744Water, Wastewater, & Sewage Treatment?Water, wastewater, and sewage treatment processes are critical for managing and mitigating pollutants in water systems.Wastewater, sanitation & biosolidsNot Available
Pathways
0 pathwaysPathway Source: PathBank

No pathways found

No metabolic pathways have been associated with this synthetic chemical

Targets
StructureProteinUniProt IDOrganismRelationshipDetails
Autotaxin structureClick to view 3D structureAutotaxinQ13822HumansPredicted (SEA)
Prediction Confidence Score
0.188
Applicability Domain
0.19 Low confidence
Statistical Significance
0.1331
Supporting Reference Compounds
40
E-value
1036.48
Click to view 3D structureLysophosphatidic acid receptor 3Q8K5E0Rattus norvegicusPredicted (SEA)
Prediction Confidence Score
0.182
Applicability Domain
0.19 Low confidence
Statistical Significance
0.0029
Supporting Reference Compounds
4
E-value
22.8877
Lysophosphatidic acid receptor 2 structureClick to view 3D structureLysophosphatidic acid receptor 2Q9HBW0HumansPredicted (SEA)
Prediction Confidence Score
0.169
Applicability Domain
0.19 Low confidence
Statistical Significance
0.2982
Supporting Reference Compounds
30
E-value
2321.39
Fatty-acid amide hydrolase 1 structureClick to view 3D structureFatty-acid amide hydrolase 1P97612Rattus norvegicusPredicted (SEA)
Prediction Confidence Score
0.151
Applicability Domain
0.216 Low confidence
Statistical Significance
0.8626
Supporting Reference Compounds
102
E-value
6715.58
Muscarinic acetylcholine receptor M2 structureClick to view 3D structureMuscarinic acetylcholine receptor M2P08172HumansPredicted (SEA)
Prediction Confidence Score
0.149
Applicability Domain
0.231 Low confidence
Statistical Significance
0.9883
Supporting Reference Compounds
373
E-value
7693.53
Muscarinic acetylcholine receptor M4 structureClick to view 3D structureMuscarinic acetylcholine receptor M4P08173HumansPredicted (SEA)
Prediction Confidence Score
0.149
Applicability Domain
0.231 Low confidence
Statistical Significance
0.9815
Supporting Reference Compounds
297
E-value
7641.13
5-hydroxytryptamine receptor 2C structureClick to view 3D structure5-hydroxytryptamine receptor 2CP28335HumansPredicted (SEA)
Prediction Confidence Score
0.149
Applicability Domain
0.179 Low confidence
Statistical Significance
0.993
Supporting Reference Compounds
823
E-value
7730.12
Voltage-gated inwardly rectifying potassium channel KCNH2 structureClick to view 3D structureVoltage-gated inwardly rectifying potassium channel KCNH2Q12809HumansPredicted (SEA)
Prediction Confidence Score
0.149
Applicability Domain
0.162 Low confidence
Statistical Significance
0.9966
Supporting Reference Compounds
1498
E-value
7758.76
5-hydroxytryptamine receptor 1A structureClick to view 3D structure5-hydroxytryptamine receptor 1AP08908HumansPredicted (SEA)
Prediction Confidence Score
0.147
Applicability Domain
0.179 Low confidence
Statistical Significance
0.9916
Supporting Reference Compounds
953
E-value
7719.76
Cytochrome P450 2C9 structureClick to view 3D structureCytochrome P450 2C9P11712HumansPredicted (SEA)
Prediction Confidence Score
0.147
Applicability Domain
0.164 Low confidence
Statistical Significance
0.9972
Supporting Reference Compounds
1245
E-value
7762.97
Click to view 3D structureFatty-acid amide hydrolase 1O08914Mus musculusPredicted (SEA)
Prediction Confidence Score
0.146
Applicability Domain
0.212 Low confidence
Statistical Significance
0.7485
Supporting Reference Compounds
46
E-value
5826.94
Cytochrome P450 3A4 structureClick to view 3D structureCytochrome P450 3A4P08684HumansPredicted (SEA)
Prediction Confidence Score
0.144
Applicability Domain
0.164 Low confidence
Statistical Significance
0.9983
Supporting Reference Compounds
1538
E-value
7771.69
5-hydroxytryptamine receptor 2A structureClick to view 3D structure5-hydroxytryptamine receptor 2AP28223HumansPredicted (SEA)
Prediction Confidence Score
0.144
Applicability Domain
0.179 Low confidence
Statistical Significance
0.9958
Supporting Reference Compounds
955
E-value
7752.23
Cytochrome P450 2D6 structureClick to view 3D structureCytochrome P450 2D6P10635HumansPredicted (SEA)
Prediction Confidence Score
0.144
Applicability Domain
0.164 Low confidence
Statistical Significance
0.9974
Supporting Reference Compounds
1130
E-value
7764.53
Thymidylate synthase ThyA structureClick to view 3D structureThymidylate synthase ThyAP9WFR9Mycobacterium tuberculosisPredicted (SEA)
Prediction Confidence Score
0.143
Applicability Domain
0.143 Low confidence
Statistical Significance
0.0343
Supporting Reference Compounds
1
E-value
266.789
Cytochrome P450 2C19 structureClick to view 3D structureCytochrome P450 2C19P33261HumansPredicted (SEA)
Prediction Confidence Score
0.142
Applicability Domain
0.164 Low confidence
Statistical Significance
0.9968
Supporting Reference Compounds
825
E-value
7760.4
Sodium-dependent dopamine transporter structureClick to view 3D structureSodium-dependent dopamine transporterQ01959HumansPredicted (SEA)
Prediction Confidence Score
0.142
Applicability Domain
0.154 Low confidence
Statistical Significance
0.9943
Supporting Reference Compounds
506
E-value
7740.7
D(4) dopamine receptor structureClick to view 3D structureD(4) dopamine receptorP51436Mus musculusPredicted (SEA)
Prediction Confidence Score
0.142
Applicability Domain
0.156 Low confidence
Statistical Significance
0.4334
Supporting Reference Compounds
16
E-value
3373.67
Click to view 3D structureSodium-dependent phosphate transport protein 2AQ06496Rattus norvegicusPredicted (SEA)
Prediction Confidence Score
0.141
Applicability Domain
0.141 Low confidence
Statistical Significance
0.0973
Supporting Reference Compounds
1
E-value
757.473
Click to view 3D structureSodium-dependent phosphate transport protein 2AQ60825Mus musculusPredicted (SEA)
Prediction Confidence Score
0.141
Applicability Domain
0.141 Low confidence
Statistical Significance
0.0973
Supporting Reference Compounds
1
E-value
757.473
Click to view 3D structure5-hydroxytryptamine receptor 2AP35363Mus musculusPredicted (SEA)
Prediction Confidence Score
0.141
Applicability Domain
0.156 Low confidence
Statistical Significance
0.8086
Supporting Reference Compounds
47
E-value
6294.58
Envelope phospholipase OPG057 structureClick to view 3D structureEnvelope phospholipase OPG057P04021Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strainWR))Predicted (SEA)
Prediction Confidence Score
0.14
Applicability Domain
0.14 Low confidence
Statistical Significance
0.1767
Supporting Reference Compounds
1
E-value
1375.36
Click to view 3D structureLysophosphatidic acid receptor 1P61794Rattus norvegicusPredicted (SEA)
Prediction Confidence Score
0.139
Applicability Domain
0.19 Low confidence
Statistical Significance
0.0544
Supporting Reference Compounds
6
E-value
423.578
Sodium-dependent noradrenaline transporter structureClick to view 3D structureSodium-dependent noradrenaline transporterP23975HumansPredicted (SEA)
Prediction Confidence Score
0.139
Applicability Domain
0.154 Low confidence
Statistical Significance
0.9959
Supporting Reference Compounds
451
E-value
7752.93
Cytochrome P450 1A2 structureClick to view 3D structureCytochrome P450 1A2P05177HumansPredicted (SEA)
Prediction Confidence Score
0.138
Applicability Domain
0.164 Low confidence
Statistical Significance
0.997
Supporting Reference Compounds
793
E-value
7761.88
Concentrations
Not Available
External Links
IdentifiersNot Available
References
Synthesis ReferenceNot Available
MSDSNot Available
General ReferencesNot Available