Perfluorotetradecanedioic acid dihydrazide (CED0006459)

Record Information

Version

1.0

Creation Date

2026-04-03 06:08:12 UTC

Update Date

2026-08-19 08:12:14 UTC

SynCED ID

CED0006459

Secondary Accession Numbers

CHEM062223

Identification

Common Name

Perfluorotetradecanedioic acid dihydrazide

Class

Small Molecule

Description

Perfluorotetradecanedioic acid dihydrazide (C14H6F24N4O2) is a chemical compound utilized across various industrial and consumer sectors. Perfluorotetradecanedioic acid dihydrazide belongs to the carboxylic acid derivatives, a subclass of carboxylic acids and derivatives within the organic compounds. With an average molecular weight of 718.19 g/mol, Perfluorotetradecanedioic acid dihydrazide is a heavy molecule. The compound is found in or released from 13 recorded sources. Within the energy, oil and gas sector as well as industrial manufacturing and chemical processing, it is used in lubricants. It is present in healthcare, pharmaceuticals and veterinary products via medical devices, and in food, food processing and cookware through food packaging. In the textiles, leather and furnishings sector, it is found in carpets, rugs, and synthetic textiles. Furthermore, it is associated with electrical and electronic equipment, including batteries, capacitors, cell phones, printed circuit boards, wires, cables, and one additional source. It is also found in one other sector. Recorded exposure routes for this compound include oral, inhalation, and touch.

Contaminant Type

PFAS

Chemical Structure

MOL SDF PDB SMILES InChI

Synonyms

Not Available

Chemical Formula

C₁₄H₆F₂₄N₄O₂

Average Molecular Mass

718.190 g/mol

Monoisotopic Mass

718.011 g/mol

CAS Registry Number

5102-53-4

IUPAC Name

Not Available

Traditional Name

Not Available

SMILES

NNC(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(=O)NN

InChI Identifier

InChI=1S/C14H6F24N4O2/c15-3(16,1(43)41-39)5(19,20)7(23,24)9(27,28)11(31,32)13(35,36)14(37,38)12(33,34)10(29,30)8(25,26)6(21,22)4(17,18)2(44)42-40/h39-40H2,(H,41,43)(H,42,44)

InChI Key

DVGAKXCCCMYSPK-UHFFFAOYSA-N

Chemical Taxonomy

Classification

Not classified

Biological Properties

Status

Detected and Not Quantified

Origin

Not Available

Cellular Locations

Not Available

Biofluid Locations

Not Available

Tissue Locations

Not Available

Applications

Not Available

Biological Roles

Not Available

Chemical Roles

Not Available

Organoleptic Effects

Not Available

Physical Properties

State

Not Available

Appearance

Not Available

Experimental Properties

Property	Value
Melting Point	Not Available
Boiling Point	Not Available
Solubility	Not Available

Predicted Properties

Not Available

Spectra

Not Available

Toxicity Profile

Toxicity Values

Not Available

Toxicity / Toxin Class

Not Available

Mechanism of Toxicity

Not Available

Carcinogenicity (IARC Classification)

Not Available

Minimum Risk Level

Not Available

Symptoms

Not Available

Treatment

Not Available

Health Effects

Health Effect	Relationship	Direction	Reference

Exposure Sources

Source ID	Source	Sector	Reference
CEDs000007	Pesticides?Pesticides are synthetic chemicals designed to prevent, destroy, or control pests that threaten crops and agricultural productivity.	Agriculture & land management	Not Available
CEDs000120	Wires and cables?Wires and cables are integral components in the transmission of electrical power and signals.	Electrical & Electronic Equipment	Not Available
CEDs000121	Printed circuit boards?Printed circuit boards (PCBs) are essential components in the manufacturing of electronic devices, serving as the backbone for electrical connections and circuit pathways.	Electrical & Electronic Equipment	Not Available
CEDs000125	Batteries?Batteries are devices that store and release electrical energy through electrochemical reactions.	Electrical & Electronic Equipment	Not Available
CEDs000130	Semiconductors?Semiconductors are materials that possess electrical conductivity between that of conductors and insulators, making them essential for various electronic applications, including transistors, diodes, and integrated circuits.	Electrical & Electronic Equipment	Not Available
CEDs000138	Lubricants?Lubricants are synthetic or petroleum-derived substances used to reduce friction between surfaces in machinery and equipment, enhancing operational efficiency and longevity.	Energy, oil & gas	Not Available
CEDs000147	Food packaging?Food packaging often utilizes synthetic chemicals, such as plastics and coatings, to enhance durability, moisture resistance, and shelf life.	Food, food processing & cookware	Not Available
CEDs000174	Lubricants?Lubricants are synthetic or petroleum-based substances used to reduce friction and wear between moving parts in machinery and equipment.	Industrial manufacturing & chemical processing	Not Available
CEDs000234	Medical devices?Medical devices often incorporate synthetic chemicals in their manufacturing processes, which can contribute to contamination in healthcare settings.	Healthcare, pharmaceuticals & veterinary products	Not Available
CEDs000451	Carpets and Rugs?Carpets and rugs are commonly manufactured using synthetic fibers such as nylon, polyester, and polypropylene, which can be derived from petrochemical sources.	Textiles, leather & furnishings	Not Available
CEDs000454	Synthetic textiles?Synthetic textiles are materials derived from man-made fibers, such as polyester, nylon, and acrylic, which are produced through chemical processes involving petrochemicals.	Textiles, leather & furnishings	Not Available
CEDs000490		Personal care & cosmetics	Not Available
CEDs000492	Cell phones?Cell phones contain a variety of synthetic chemicals and materials, including plastics, metals, and glass, which can contribute to environmental contamination.	Electrical & Electronic Equipment	Not Available
CEDs000493	Capacitors?Capacitors are electronic components that store and release electrical energy, often using dielectric materials that can include synthetic chemicals.	Electrical & Electronic Equipment	Not Available

Pathways

0 pathwaysPathway Source: PathBank

No pathways found

No metabolic pathways have been associated with this synthetic chemical

Targets

Structure	Protein	UniProt ID	Organism	Relationship	Details
Click to view 3D structure	Histone deacetylase-like amidohydrolase	Q70I53	Alcaligenes sp. (strain DSM 11172)	Predicted (SEA)	Prediction Confidence Score 0.331 Applicability Domain 0.382 Statistical Significance 1.30e-04 Supporting Reference Compounds 11 E-value 1.01204
Click to view 3D structure	Protein deacetylase HDAC6	Q9UBN7	Humans	Predicted (SEA)	Prediction Confidence Score 0.277 Applicability Domain 0.325 Statistical Significance 0.1285 Supporting Reference Compounds 553 E-value 1000.44
Click to view 3D structure	Histone deacetylase 8	Q9BY41	Humans	Predicted (SEA)	Prediction Confidence Score 0.239 Applicability Domain 0.333 Statistical Significance 0.2424 Supporting Reference Compounds 317 E-value 1886.91
Click to view 3D structure	Histone deacetylase 7	Q8WUI4	Humans	Predicted (SEA)	Prediction Confidence Score 0.237 Applicability Domain 0.333 Statistical Significance 0.1305 Supporting Reference Compounds 148 E-value 1015.62
Click to view 3D structure	Utrophin	E9Q6R7	Mus musculus	Predicted (SEA)	Prediction Confidence Score 0.229 Applicability Domain 0.229 Low confidence Statistical Significance 0.0249 Supporting Reference Compounds 1 E-value 193.533
Click to view 3D structure	Histone deacetylase 1	Q13547	Humans	Predicted (SEA)	Prediction Confidence Score 0.213 Applicability Domain 0.333 Statistical Significance 0.5933 Supporting Reference Compounds 497 E-value 4618.79
Click to view 3D structure	Acetylpolyamine amidohydrolase	Q48935	Mycoplana ramosa	Predicted (SEA)	Prediction Confidence Score 0.211 Applicability Domain 0.211 Low confidence Statistical Significance 9.00e-04 Supporting Reference Compounds 1 E-value 7.00643
Click to view 3D structure	Carbonic anhydrase 2	P00918	Humans	Predicted (SEA)	Prediction Confidence Score 0.191 Applicability Domain 0.208 Low confidence Statistical Significance 0.6829 Supporting Reference Compounds 472 E-value 5316.32
Click to view 3D structure	Carbonic anhydrase 1	P00915	Humans	Predicted (SEA)	Prediction Confidence Score 0.191 Applicability Domain 0.208 Low confidence Statistical Significance 0.629 Supporting Reference Compounds 407 E-value 4896.4
Click to view 3D structure	Carbonic anhydrase 7	P43166	Humans	Predicted (SEA)	Prediction Confidence Score 0.186 Applicability Domain 0.25 Low confidence Statistical Significance 0.581 Supporting Reference Compounds 242 E-value 4523.12
Click to view 3D structure	Cystathionine beta-lyase MetC	P06721	Escherichia coli K-12	Predicted (SEA)	Prediction Confidence Score 0.182 Applicability Domain 0.182 Low confidence Statistical Significance 0.0263 Supporting Reference Compounds 1 E-value 205.133
Click to view 3D structure	Phosphoglycerate kinase	P00560	Saccharomyces cerevisiae S288c	Predicted (SEA)	Prediction Confidence Score 0.176 Applicability Domain 0.176 Low confidence Statistical Significance 5.20e-04 Supporting Reference Compounds 1 E-value 4.04816
Click to view 3D structure	4-aminobutyrate aminotransferase, mitochondrial	P80147	Sus scrofa	Predicted (SEA)	Prediction Confidence Score 0.171 Applicability Domain 0.214 Low confidence Statistical Significance 7.50e-04 Supporting Reference Compounds 2 E-value 5.83869
Click to view 3D structure	Inward rectifier potassium channel 2	P35561	Mus musculus	Predicted (SEA)	Prediction Confidence Score 0.171 Applicability Domain 0.171 Low confidence Statistical Significance 0.1546 Supporting Reference Compounds 1 E-value 1203.78
Click to view 3D structure	Cyclic AMP-dependent transcription factor ATF-1	P18846	Humans	Predicted (SEA)	Prediction Confidence Score 0.17 Applicability Domain 0.174 Low confidence Statistical Significance 0.1021 Supporting Reference Compounds 3 E-value 794.607
Click to view 3D structure	Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2	O43314	Humans	Predicted (SEA)	Prediction Confidence Score 0.17 Applicability Domain 0.17 Low confidence Statistical Significance 0.0018 Supporting Reference Compounds 1 E-value 14.1686
Click to view 3D structure	Juvenile hormone esterase	Q9GPG0	Manduca sexta	Predicted (SEA)	Prediction Confidence Score 0.17 Applicability Domain 0.182 Low confidence Statistical Significance 0.0082 Supporting Reference Compounds 2 E-value 63.6028
Click to view 3D structure	Carbonic anhydrase 4	P22748	Humans	Predicted (SEA)	Prediction Confidence Score 0.17 Applicability Domain 0.25 Low confidence Statistical Significance 0.7196 Supporting Reference Compounds 193 E-value 5602.42
Click to view 3D structure	Carbonic anhydrase 9	Q16790	Humans	Predicted (SEA)	Prediction Confidence Score 0.169 Applicability Domain 0.2 Low confidence Statistical Significance 0.8393 Supporting Reference Compounds 372 E-value 6533.65
Click to view 3D structure	Liver carboxylesterase 1	P23141	Humans	Predicted (SEA)	Prediction Confidence Score 0.169 Applicability Domain 0.182 Low confidence Statistical Significance 0.307 Supporting Reference Compounds 55 E-value 2390.05
Click to view 3D structure	Cocaine esterase	O00748	Humans	Predicted (SEA)	Prediction Confidence Score 0.168 Applicability Domain 0.182 Low confidence Statistical Significance 0.2738 Supporting Reference Compounds 40 E-value 2131.59
Click to view 3D structure	Fatty-acid amide hydrolase 1	O00519	Humans	Predicted (SEA)	Prediction Confidence Score 0.167 Applicability Domain 0.182 Low confidence Statistical Significance 0.8 Supporting Reference Compounds 106 E-value 6228.02
Click to view 3D structure	Liver carboxylesterase	Q29550	Sus scrofa	Predicted (SEA)	Prediction Confidence Score 0.165 Applicability Domain 0.182 Low confidence Statistical Significance 0.1291 Supporting Reference Compounds 20 E-value 1005.42
Click to view 3D structure	CG8425-PA [Drosophila melanogaster]	A1ZA98	Drosophila melanogaster	Predicted (SEA)	Prediction Confidence Score 0.165 Applicability Domain 0.182 Low confidence Statistical Significance 0.0093 Supporting Reference Compounds 4 E-value 72.3998
Click to view 3D structure	Tyrosine-protein kinase Lck	P06239	Humans	Predicted (SEA)	Prediction Confidence Score 0.164 Applicability Domain 0.186 Low confidence Statistical Significance 0.9843 Supporting Reference Compounds 1130 E-value 7662.39