(2H-Perfluoroethoxy)methyloxirane (CED0150369)

Record Information

Version

1.0

Creation Date

2026-04-03 06:36:03 UTC

Update Date

2026-08-23 00:12:40 UTC

SynCED ID

CED0150369

Secondary Accession Numbers

CHEM062364

Identification

Common Name

(2H-Perfluoroethoxy)methyloxirane

Class

Small Molecule

Description

(2H-Perfluoroethoxy)methyloxirane belongs to the epoxides, a class of organoheterocyclic compounds within the organic compounds. This compound has the chemical formula C5H6F4O2 and an average molecular weight of 174.09 g/mol. The substance is found in or released from 13 recorded sources across multiple sectors. Within electrical and electronic equipment, it is associated with cell phones, capacitors, batteries, printed circuit boards, wires and cables, and one additional source. In the textiles, leather and furnishings sector, it is found in carpets, rugs, and synthetic textiles. It is also present in food packaging within the food, food processing and cookware sector, and in medical devices within the healthcare, pharmaceuticals and veterinary products sector. Additionally, it is used as a lubricant in both the energy, oil and gas sector and the industrial manufacturing and chemical processing sector, along with one more sector. Recorded routes of exposure for this compound include oral, touch, and inhalation.

Contaminant Type

PFAS

Chemical Structure

MOL SDF PDB SMILES InChI

Synonyms

Not Available

Chemical Formula

C₅H₆F₄O₂

Average Molecular Mass

174.095 g/mol

Monoisotopic Mass

174.030 g/mol

CAS Registry Number

85567-21-1

IUPAC Name

Not Available

Traditional Name

Not Available

SMILES

FC(F)C(F)(F)OCC1CO1

InChI Identifier

InChI=1S/C5H6F4O2/c6-4(7)5(8,9)11-2-3-1-10-3/h3-4H,1-2H2

InChI Key

HFNPKDDYCOMYLN-UHFFFAOYSA-N

Chemical Taxonomy

Classification

Not classified

Biological Properties

Status

Detected and Not Quantified

Origin

Not Available

Cellular Locations

Not Available

Biofluid Locations

Not Available

Tissue Locations

Not Available

Applications

Not Available

Biological Roles

Not Available

Chemical Roles

Not Available

Organoleptic Effects

Not Available

Physical Properties

State

Not Available

Appearance

Not Available

Experimental Properties

Property	Value
Melting Point	Not Available
Boiling Point	Not Available
Solubility	Not Available

Predicted Properties

Not Available

Spectra

Not Available

Toxicity Profile

Toxicity Values

Toxicity Value	Organism	Dose Descriptor	Route of Exposure	Predicted or Experimental	Toxicity Rating	Reference
1500.0 Log mg/kg [840:2700]	Rat	LD50	oral	predicted	Not Available	Not Available

Toxicity / Toxin Class

Not Available

Mechanism of Toxicity

Not Available

Carcinogenicity (IARC Classification)

Not Available

Minimum Risk Level

Not Available

Symptoms

Not Available

Treatment

Not Available

Health Effects

Health Effect	Relationship	Direction	Description	Reference

Exposure Sources

Source ID	Source	Sector	Reference
CEDs000007	Pesticides?Pesticides are synthetic chemicals designed to prevent, destroy, or control pests that threaten crops and agricultural productivity.	Agriculture & land management	Not Available
CEDs000120	Wires and cables?Wires and cables are integral components in the transmission of electrical power and signals.	Electrical & Electronic Equipment	Not Available
CEDs000121	Printed circuit boards?Printed circuit boards (PCBs) are essential components in the manufacturing of electronic devices, serving as the backbone for electrical connections and circuit pathways.	Electrical & Electronic Equipment	Not Available
CEDs000125	Batteries?Batteries are devices that store and release electrical energy through electrochemical reactions.	Electrical & Electronic Equipment	Not Available
CEDs000130	Semiconductors?Semiconductors are materials that possess electrical conductivity between that of conductors and insulators, making them essential for various electronic applications, including transistors, diodes, and integrated circuits.	Electrical & Electronic Equipment	Not Available
CEDs000138	Lubricants?Lubricants are synthetic or petroleum-derived substances used to reduce friction between surfaces in machinery and equipment, enhancing operational efficiency and longevity.	Energy, oil & gas	Not Available
CEDs000147	Food packaging?Food packaging often utilizes synthetic chemicals, such as plastics and coatings, to enhance durability, moisture resistance, and shelf life.	Food, food processing & cookware	Not Available
CEDs000174	Lubricants?Lubricants are synthetic or petroleum-based substances used to reduce friction and wear between moving parts in machinery and equipment.	Industrial manufacturing & chemical processing	Not Available
CEDs000234	Medical devices?Medical devices often incorporate synthetic chemicals in their manufacturing processes, which can contribute to contamination in healthcare settings.	Healthcare, pharmaceuticals & veterinary products	Not Available
CEDs000451	Carpets and Rugs?Carpets and rugs are commonly manufactured using synthetic fibers such as nylon, polyester, and polypropylene, which can be derived from petrochemical sources.	Textiles, leather & furnishings	Not Available
CEDs000454	Synthetic textiles?Synthetic textiles are materials derived from man-made fibers, such as polyester, nylon, and acrylic, which are produced through chemical processes involving petrochemicals.	Textiles, leather & furnishings	Not Available
CEDs000490		Personal care & cosmetics	Not Available
CEDs000492	Cell phones?Cell phones contain a variety of synthetic chemicals and materials, including plastics, metals, and glass, which can contribute to environmental contamination.	Electrical & Electronic Equipment	Not Available
CEDs000493	Capacitors?Capacitors are electronic components that store and release electrical energy, often using dielectric materials that can include synthetic chemicals.	Electrical & Electronic Equipment	Not Available
CEDs000519	Electrodes?Electrodes, used in various electrical and electronic applications, can be a source of synthetic chemical contamination due to the materials from which they are constructed and the processes involved in their manufacturing.	Electrical & Electronic Equipment	PubChem
CEDs000696	Nanotechnology?Nanotechnology involves the manipulation of materials at the molecular or atomic level, typically within the range of 1 to 100 nanometers.	Industrial manufacturing & chemical processing	PubChem
CEDs000739	Inks?Inks are complex mixtures composed of pigments or dyes, solvents, resins, and additives used primarily for printing and writing applications.	Paper, pulp & fiber products	PubChem
CEDs000744	Water, Wastewater, & Sewage Treatment?Water, wastewater, and sewage treatment processes are critical for managing and mitigating pollutants in water systems.	Wastewater, sanitation & biosolids	PubChem

Pathways

0 pathwaysPathway Source: PathBank

No pathways found

No metabolic pathways have been associated with this synthetic chemical

Targets

Structure	Protein	UniProt ID	Organism	Relationship	Details
Click to view 3D structure	Autotaxin	Q13822	Humans	Predicted (SEA)	Prediction Confidence Score 0.194 Applicability Domain 0.196 Low confidence Statistical Significance 0.0934 Supporting Reference Compounds 40 E-value 727.19
Click to view 3D structure	Lysophosphatidic acid receptor 3	Q8K5E0	Rattus norvegicus	Predicted (SEA)	Prediction Confidence Score 0.189 Applicability Domain 0.196 Low confidence Statistical Significance 0.0025 Supporting Reference Compounds 4 E-value 19.3845
Click to view 3D structure	Lysophosphatidic acid receptor 2	Q9HBW0	Humans	Predicted (SEA)	Prediction Confidence Score 0.175 Applicability Domain 0.196 Low confidence Statistical Significance 0.2179 Supporting Reference Compounds 30 E-value 1696.18
Click to view 3D structure	Cytochrome P450 3A4	P08684	Humans	Predicted (SEA)	Prediction Confidence Score 0.159 Applicability Domain 0.188 Low confidence Statistical Significance 0.9959 Supporting Reference Compounds 1538 E-value 7752.93
Click to view 3D structure	Muscarinic acetylcholine receptor M2	P08172	Humans	Predicted (SEA)	Prediction Confidence Score 0.156 Applicability Domain 0.211 Low confidence Statistical Significance 0.9801 Supporting Reference Compounds 373 E-value 7630.08
Click to view 3D structure	Inositol monophosphatase 1	P20456	Bos taurus	Predicted (SEA)	Prediction Confidence Score 0.155 Applicability Domain 0.155 Low confidence Statistical Significance 0.0844 Supporting Reference Compounds 1 E-value 657.047
Click to view 3D structure	Muscarinic acetylcholine receptor M4	P08173	Humans	Predicted (SEA)	Prediction Confidence Score 0.153 Applicability Domain 0.211 Low confidence Statistical Significance 0.9745 Supporting Reference Compounds 297 E-value 7586.17
Click to view 3D structure	Cytochrome P450 2D6	P10635	Humans	Predicted (SEA)	Prediction Confidence Score 0.151 Applicability Domain 0.188 Low confidence Statistical Significance 0.9958 Supporting Reference Compounds 1130 E-value 7752.23
Click to view 3D structure	Cytochrome P450 2C19	P33261	Humans	Predicted (SEA)	Prediction Confidence Score 0.151 Applicability Domain 0.188 Low confidence Statistical Significance 0.9948 Supporting Reference Compounds 825 E-value 7744.21
Click to view 3D structure	Cytochrome P450 2C9	P11712	Humans	Predicted (SEA)	Prediction Confidence Score 0.151 Applicability Domain 0.188 Low confidence Statistical Significance 0.9965 Supporting Reference Compounds 1245 E-value 7757.75
Click to view 3D structure	D(4) dopamine receptor	P51436	Mus musculus	Predicted (SEA)	Prediction Confidence Score 0.15 Applicability Domain 0.161 Low confidence Statistical Significance 0.3375 Supporting Reference Compounds 16 E-value 2627.26
Click to view 3D structure	Voltage-gated inwardly rectifying potassium channel KCNH2	Q12809	Humans	Predicted (SEA)	Prediction Confidence Score 0.15 Applicability Domain 0.155 Low confidence Statistical Significance 0.9964 Supporting Reference Compounds 1498 E-value 7757.05
Click to view 3D structure	Cytochrome P450 1A2	P05177	Humans	Predicted (SEA)	Prediction Confidence Score 0.149 Applicability Domain 0.188 Low confidence Statistical Significance 0.9933 Supporting Reference Compounds 793 E-value 7733.0
Click to view 3D structure	Sodium-dependent dopamine transporter	Q01959	Humans	Predicted (SEA)	Prediction Confidence Score 0.149 Applicability Domain 0.16 Low confidence Statistical Significance 0.9904 Supporting Reference Compounds 506 E-value 7709.95
Click to view 3D structure	5-hydroxytryptamine receptor 2B	Q02152	Mus musculus	Predicted (SEA)	Prediction Confidence Score 0.149 Applicability Domain 0.161 Low confidence Statistical Significance 0.4574 Supporting Reference Compounds 20 E-value 3560.59
Click to view 3D structure	Fatty-acid amide hydrolase 1	P97612	Rattus norvegicus	Predicted (SEA)	Prediction Confidence Score 0.148 Applicability Domain 0.224 Low confidence Statistical Significance 0.8805 Supporting Reference Compounds 102 E-value 6854.39
Click to view 3D structure	D(3) dopamine receptor	P30728	Mus musculus	Predicted (SEA)	Prediction Confidence Score 0.148 Applicability Domain 0.161 Low confidence Statistical Significance 0.1663 Supporting Reference Compounds 6 E-value 1294.4
Click to view 3D structure	Thymidylate synthase ThyA	P9WFR9	Mycobacterium tuberculosis	Predicted (SEA)	Prediction Confidence Score 0.148 Applicability Domain 0.148 Low confidence Statistical Significance 0.0231 Supporting Reference Compounds 1 E-value 179.832
Click to view 3D structure	Lysophosphatidic acid receptor 1	P61794	Rattus norvegicus	Predicted (SEA)	Prediction Confidence Score 0.147 Applicability Domain 0.196 Low confidence Statistical Significance 0.0267 Supporting Reference Compounds 6 E-value 207.702
Click to view 3D structure	5-hydroxytryptamine receptor 1A	Q64264	Mus musculus	Predicted (SEA)	Prediction Confidence Score 0.146 Applicability Domain 0.161 Low confidence Statistical Significance 0.8235 Supporting Reference Compounds 52 E-value 6411.12
Click to view 3D structure	5-hydroxytryptamine receptor 2A	P35363	Mus musculus	Predicted (SEA)	Prediction Confidence Score 0.145 Applicability Domain 0.161 Low confidence Statistical Significance 0.7573 Supporting Reference Compounds 47 E-value 5895.29
Click to view 3D structure	Sodium-dependent phosphate transport protein 2A	Q06496	Rattus norvegicus	Predicted (SEA)	Prediction Confidence Score 0.145 Applicability Domain 0.145 Low confidence Statistical Significance 0.0781 Supporting Reference Compounds 1 E-value 608.002
Click to view 3D structure	Sodium-dependent phosphate transport protein 2A	Q60825	Mus musculus	Predicted (SEA)	Prediction Confidence Score 0.145 Applicability Domain 0.145 Low confidence Statistical Significance 0.0781 Supporting Reference Compounds 1 E-value 608.002
Click to view 3D structure	Muscarinic acetylcholine receptor M1	P11229	Humans	Predicted (SEA)	Prediction Confidence Score 0.144 Applicability Domain 0.149 Low confidence Statistical Significance 0.9912 Supporting Reference Compounds 385 E-value 7716.57
Click to view 3D structure	Sodium-dependent noradrenaline transporter	P23975	Humans	Predicted (SEA)	Prediction Confidence Score 0.144 Applicability Domain 0.16 Low confidence Statistical Significance 0.9932 Supporting Reference Compounds 451 E-value 7732.3