Lixisenatide (CED0004623)

Record Information
Version1.0
Creation Date2026-04-04 18:12:18 UTC
Update Date2026-04-14 17:41:40 UTC
Accession NumberCHEM077371
Identification
Common NameLixisenatide
ClassSmall Molecule
Description
Lixisenatide is an organic compound with the formula C215H347N61O65S1. Lixisenatide belongs to the polypeptides, a class of organic polymers within the organic compounds. In terms of biological activity, it acts as an agonist of the Glucagon-like peptide 1 receptor (GLP1R). The compound is found in or released from three recorded sources, including antennas within electrical and electronic equipment, as well as pharmaceuticals and veterinary products such as blood glucose lowering drugs (excluding insulins) and insulins and analogues. The recorded route of exposure for lixisenatide is subcutaneous.
Contaminant TypeNot Available
Chemical Structure
MOLSDFPDBSMILESInChI
SynonymsNot Available
Chemical FormulaC215H347N61O65S1
Average Molecular MassNot Available
Monoisotopic Mass4855.544 g/mol
CAS Registry Number320367-13-3
IUPAC NameNot Available
Traditional NameNot Available
SMILESNot Available
InChI IdentifierInChI=1S/C215H347N61O65S/c1-16-115(10)173(210(337)256-141(68-74-170(299)300)194(321)261-148(94-122-98-232-126-50-24-23-49-124(122)126)199(326)258-143(89-111(2)3)196(323)247-134(58-32-40-83-223)189(316)262-149(96-160(226)285)180(307)235-100-161(286)233-104-165(290)274-85-42-60-156(274)207(334)267-154(108-280)206(333)265-151(105-277)181(308)237-101-162(287)239-117(12)213(340)276-87-44-62-158(276)214(341)275-86-43-61-157(275)208(335)268-153(107-279)204(331)249-132(56-30-38-81-221)187(314)246-131(55-29-37-80-220)186(313)245-130(54-28-36-79-219)185(312)244-129(53-27-35-78-218)184(311)243-128(52-26-34-77-217)183(310)242-127(176(227)303)51-25-33-76-216)272-201(328)146(92-120-45-19-17-20-46-120)260-197(324)144(90-112(4)5)257-190(317)135(59-41-84-231-215(228)229)255-209(336)172(114(8)9)271-177(304)116(11)240-182(309)138(65-71-167(293)294)251-192(319)139(66-72-168(295)296)252-193(320)140(67-73-169(297)298)253-195(322)142(75-88-342-15)254-191(318)137(63-69-159(225)284)250-188(315)133(57-31-39-82-222)248-203(330)152(106-278)266-198(325)145(91-113(6)7)259-200(327)150(97-171(301)302)263-205(332)155(109-281)269-212(339)175(119(14)283)273-202(329)147(93-121-47-21-18-22-48-121)264-211(338)174(118(13)282)270-164(289)103-236-179(306)136(64-70-166(291)292)241-163(288)102-234-178(305)125(224)95-123-99-230-110-238-123/h17-24,45-50,98-99,110-119,125,127-158,172-175,232,277-283H,16,25-44,51-97,100-109,216-224H2,1-15H3,(H2,225,284)(H2,226,285)(H2,227,303)(H,230,238)(H,233,286)(H,234,305)(H,235,307)(H,236,306)(H,237,308)(H,239,287)(H,240,309)(H,241,288)(H,242,310)(H,243,311)(H,244,312)(H,245,313)(H,246,314)(H,247,323)(H,248,330)(H,249,331)(H,250,315)(H,251,319)(H,252,320)(H,253,322)(H,254,318)(H,255,336)(H,256,337)(H,257,317)(H,258,326)(H,259,327)(H,260,324)(H,261,321)(H,262,316)(H,263,332)(H,264,338)(H,265,333)(H,266,325)(H,267,334)(H,268,335)(H,269,339)(H,270,289)(H,271,304)(H,272,328)(H,273,329)(H,291,292)(H,293,294)(H,295,296)(H,297,298)(H,299,300)(H,301,302)(H4,228,229,231)
InChI KeyXVVOERDUTLJJHN-UHFFFAOYSA-N
Chemical Taxonomy
ClassificationNot classified
Biological Properties
StatusDetected and Not Quantified
OriginNot Available
Cellular LocationsNot Available
Biofluid LocationsNot Available
Tissue LocationsNot Available
ApplicationsNot Available
Biological RolesNot Available
Chemical RolesNot Available
Organoleptic EffectsNot Available
Physical Properties
StateNot Available
AppearanceNot Available
Experimental Properties
PropertyValue
Melting PointNot Available
Boiling PointNot Available
SolubilityNot Available
Predicted PropertiesNot Available
Spectra
SpectraNot Available
Toxicity Profile
Mechanism of ToxicityNot Available
Carcinogenicity (IARC Classification)Not Available
Minimum Risk LevelNot Available
SymptomsNot Available
TreatmentNot Available
Toxicity ValuesNot Available
Health Effects
Health EffectRelationshipDirectionReference
Exposure Sources
Source IDSourceSectorReference
262Insulins and analoguesHealthcare, pharmaceuticals & veterinary productsNot Available
263Blood glucose lowering drugs, excl. insulinsHealthcare, pharmaceuticals & veterinary productsNot Available
506AntennasElectrical & Electronic EquipmentNot Available
Pathways
0 pathways

No pathways found

No metabolic pathways have been associated with this synthetic chemical

Targets
StructureProteinUniProt IDOrganismRelationshipDetails
Glucagon-like peptide 1 receptor structureClick to view 3D structureGlucagon-like peptide 1 receptorP43220HumansPredicted (SEA)56.8299
Click to view 3D structureSclerostinQ99P67Rattus norvegicusPredicted (SEA)48.7336
Click to view 3D structureDickkopf WNT-signaling pathway inhibitor 1A6I0Z0Rattus norvegicusPredicted (SEA)49.6678
Click to view 3D structureG-protein coupled receptor MthO97148Drosophila melanogasterPredicted (SEA)50.7577
Neuropeptide Y receptor type 2 structureClick to view 3D structureNeuropeptide Y receptor type 2P49146HumansPredicted (SEA)73.5675
Click to view 3D structureGlucagon-like peptide 2 receptorQ9Z0W0Rattus norvegicusPredicted (SEA)57.7641
Click to view 3D structureApical membrane antigen 1Q7KQK5Plasmodium falciparum (isolate 3D7)Predicted (SEA)56.2071
Click to view 3D structureGlucagon-like peptide 1 receptorO35659Mus musculusPredicted (SEA)59.3211
Glucagon receptor structureClick to view 3D structureGlucagon receptorP47871HumansPredicted (SEA)64.1478
Neuropeptide Y receptor type 1 structureClick to view 3D structureNeuropeptide Y receptor type 1P25929HumansPredicted (SEA)83.7658
Caveolin-1 structureClick to view 3D structureCaveolin-1Q03135HumansPredicted (SEA)61.1116
Glucagon-like peptide 2 receptor structureClick to view 3D structureGlucagon-like peptide 2 receptorO95838HumansPredicted (SEA)61.5009
Click to view 3D structureGlucagon receptorP30082Rattus norvegicusPredicted (SEA)65.4712
Gastric inhibitory polypeptide receptor structureClick to view 3D structureGastric inhibitory polypeptide receptorP48546HumansPredicted (SEA)58.1534
Click to view 3D structureAlpha-cobratoxinP01391Naja kaouthiaPredicted (SEA)70.9206
Click to view 3D structureGlucagon receptorQ61606Mus musculusPredicted (SEA)64.4592
Click to view 3D structureGlucagon-like peptide 1 receptorF8V479Macaca fascicularisPredicted (SEA)61.0338
Click to view 3D structureGlucagon-like peptide 1 receptorP32301Rattus norvegicusPredicted (SEA)44.4519
Prolactin-releasing peptide structureClick to view 3D structureProlactin-releasing peptideP81277HumansPredicted (SEA)85.8677
Click to view 3D structureAppetite-regulating hormoneQ9BDJ6Bos taurusPredicted (SEA)58.7762
Appetite-regulating hormone structureClick to view 3D structureAppetite-regulating hormoneQ9UBU3HumansPredicted (SEA)61.1116
Click to view 3D structureGlucagon-1O42143Xenopus laevisPredicted (SEA)85.712
Syntenin-1 structureClick to view 3D structureSyntenin-1O00560HumansPredicted (SEA)49.045
Melanocortin receptor 4 structureClick to view 3D structureMelanocortin receptor 4P32245HumansPredicted (SEA)163.016
Delta-type opioid receptor structureClick to view 3D structureDelta-type opioid receptorP41143HumansPredicted (SEA)314.511
Concentrations
Not Available
External Links
IdentifiersNot Available
References
Synthesis ReferenceNot Available
MSDSNot Available
General ReferencesNot Available