Silodosin (CED0007760)

Silodosin is an organic compound with the chemical formula C25H32F3N3O4 and an average molecular weight of 495.54 g/mol. Silodosin belongs to the indolecarboxylic acids and derivatives, a subclass of indoles and derivatives within the organic compounds. This compound is identified as being released from or found in two recorded sources: household cleaning and consumer products, specifically non electric simulated smoking devices, and healthcare, pharmaceuticals and veterinary products, where it is used as a drug for benign prostatic hypertrophy. The recorded route of exposure for this substance is oral. In terms of its biological activity, silodosin interacts with six recorded protein targets. It functions as an antagonist or blocker of the alpha-1A adrenergic receptor (ADRA1A), the alpha-1B adrenergic receptor (ADRA1B), and the alpha-1D adrenergic receptor (ADRA1D). Additionally, it targets the voltage-gated inwardly rectifying potassium channel KCNH2 as well as two other proteins.